Clinical trials: Allergic Rhinitis (Disorder)
Allergic Rhinitis, Allergic Rhinoconjunctivitis
Efficacy and Safety of Norketotifen in Adults With Allergic Rhinitis
This is a Phase 2a study to evaluate the efficacy and safety of Norketotifen (NKT) in subjects with allergic rhinitis.
- Trial name
- NCT03887026
- Testing
- Norketotifen
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Emergo Therapeutics, Inc.
Allergic Rhinitis, Chronic Urticaria
Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 6 Months to 11 Months
To determine the safety of levocetirizine in children ages 6-11 months with symptoms of allergic rhinitis or chronic idiopathic urticaria.
- Trial name
- BALL (NCT00628108)
- Testing
- Levocetirizine 1.25 mg
- Where
- 26 sites in United States
- Volunteers
- 69 people
- Sponsor
- UCB Pharma
Allergic Rhinitis, Grass Allergy
Compliance to the Treatment With GRAZAX® Tablets in Patients With Seasonal Grass Pollen Rhinoconjunctivitis
Adherence to treatment is crucial to the efficacy of sublingual immunotherapy of allergic diseases. GRAZAX® is a registered drug in Europe, with established efficacy in the treatment of allergic rhinitis, which has to be taken…
- Trial name
- GT-17 (NCT01728285)
- Testing
- Electronic compliance device (Memozax®)
- Where
- Italy
- Volunteers
- 261 people
- Sponsor
- ALK-Abelló A/S
Allergic Asthma, Allergy to House Dust Mite
Role of Indoor Pollutants on House Dust Mite Allergic Asthma
It seems that the aldehydes and NO2, at the levels found indoor, could be the aggravating factors for an allergic response. However this effect has not been demonstrated.
- Trial name
- NCT01019291
- Testing
- Formaldehyde and NO2 (Exposure to indoor pollutants)
- Where
- France
- Sponsor
- University Hospital, Strasbourg, France
Perennial Allergic Rhinitis, Rhinitis, Allergic
Efficacy and Safety of AM-301 on Allergic Symptoms of Perennial Allergic Rhinitis Sufferers
Alleviation of allergic symptoms induced by house dust mites when using the medical device AM-301. This clinical investigation explored the efficacy and safety of AM-301 when used to reduce symptoms of house dust mite sufferers.
- Trial name
- NCT05122143
- Testing
- Treatment A, Treatment B, Treatment C
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- Altamira Medica Ltd.
Perennial Rhinitis
Local IgE in Subjects With Allergic or Non-allergic Rhinitis
The purpose of the study is to investigate the incidence of non-allergic rhinitis on a not selected group of young students (n=100-300). Students will be selected by public posting.
- Trial name
- LISA (NCT02810535)
- Testing
- Observation
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Nasal Allergy
Budesonide Nasal Irrigation Versus Fluticasone Propionate Nasal Spray in Treating Allergic Rhinitis Patients
Budesonide is a medication of the corticosteroid type. Available as an inhaler, nebulization solution, The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease is used for allergic…
- Trial name
- NCT06858423
- Testing
- Budesonide buffered with 0.9% isotonic saline., Fluticasone propionate nasal spray., 0.9% saline for nasal irrigation.
- Where
- Egypt
- Volunteers
- 360 people
- Sponsor
- Benha University
Allergic Rhinitis
A Study of IL4Rα Monoclonal Antibody in Patients With Uncontrolled Seasonal Allergic Rhinitis.
Allergic rhinitis (AR) is a non-infectious chronic inflammatory disease of the nasal mucosa mainly mediated by immunoglobulin E after exposure to allergens in atopic individuals.
- Trial name
- NCT06028490
- Testing
- GR1802 injection-1, GR1802 injection-2
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zheng Liu ENT
Seasonal Allergic Rhinitis
Safety, Pharmacokinetics, and Efficacy of Bepotastine Besilate Nasal Product After Ragweed Pollen Exposure in an Environmental Chamber
The purpose of this study is to examine the safety and efficacy of bepotastine besilate nasal product in seasonal allergic rhinitis patients.
- Trial name
- NCT01222299
- Testing
- bepotastine besilate nasal product - low dose, bepotastine besilate nasal product - medium dose, bepotastine besilate nasal product - high dose
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Bausch & Lomb Incorporated
Allergy, Asthma
Roflumilast In-Vitro Basophil Release
This study is looking for allergic asthmatics. Lung and allergy testing will be done to verify. If qualified, blood will be drawn for laboratory studies.
- Trial name
- NCT00613587
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Creighton University
Allergic Rhinitis
The Dysbiosis of the Intestinal Microbiota in Individuals With Allergic Rhinitis (MICRORIN)
Allergic rhinitis (AR) is triggered by environmental allergens such as pollen and mites, and is associated with several symptoms such as itching and nasal congestion, sneezing or tearing and redness of the eyes.
- Trial name
- MICRORIN (NCT03946553)
- Where
- Spain
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain
Atopic Dermatitis, Allergic Rhinitis
Prevention Allergic Disease of Infant With Probiotics During Pregnancy and Neonatal Period
The purpose of this study is to determine whether childhood atopic disease decrease or not after allowing allergic mothers intake of probiotic (Lactobacillus GG) in second trimester, followed by infant intake for 6 months after…
- Conditions
- Atopic Dermatitis, Allergic Rhinitis, Asthma
- Trial name
- NCT00325273
- Testing
- Lactobacillus rhamnosus GG
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Chang Gung Memorial Hospital
Non-allergic Rhinitis
Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis
Chronic rhinitis is affecting more than 200 million people worldwide. Its prevalence is estimated to be as high as 30% of the Western population.
- Trial name
- NCT02288156
- Testing
- Capsaicin
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Rhinitis, Allergic, Perennial
Clinical Study, Non Inferiority Between Noex® 32µg Versus Budecort Aqua® 32µg in Treatment of Alergic Rhinitis
This study is to evaluate non inferiority of Eurofarma budesonide nasal spary x referral Astrazeneca budesonide. Half patients will receive Eurofarma medication and half patients will receive Astrazeneca medication.
- Trial name
- RINEX32 (NCT02972866)
- Testing
- Budesonide
- Where
- Brazil
- Sponsor
- Eurofarma Laboratorios S.A.
ALLERGIC RHINITIS
Repeated Nasal Challenge in Skin Prick-puncture Negative and Intradermal Positive Dust Mite Allergic Rhinitis Patients
Subjects who have a clinical history of perennial rhinitis symptoms associated with dust exposure or not associated with other perennial allergens, will have a positive challenge with Dermatophagoides pteronyssinus.
- Trial name
- DUSTMITE (NCT01179282)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Allergic Rhinitis Due to Grass Pollens
International Registry on the Quality of Life of Patients With Grass-pollen-induced Allergic Rhinitis
The purpose of the present study is to describe patient's perception of quality of life and effectiveness of ORALAIR® over a follow-up period up to 5 years, in real-life settings.
- Trial name
- ALTO (NCT02041624)
- Where
- France
- Volunteers
- 740 people
- Sponsor
- Stallergenes Greer
Seasonal Allergic Rhinitis, Rhinoconjunctivitis
Efficacy and Safety of PQ Grass in Subjects With Seasonal Allergic Rhinitis and/or Rhinoconjunctivitis Induced by Grass Pollen
The PQGrass306 (G306) clinical trial is the pivotal Phase III efficacy clinical trial of PQ Grass. The aim of the G306 pivotal clinical trial is to confirm the efficacy and safety of the optimal effective dose of PQ Grass 27600…
- Trial name
- NCT05540717
- Testing
- PQ Grass
- Where
- 102 sites in United States, Austria and 4 more
- Volunteers
- 555 people
- Sponsor
- Allergy Therapeutics
Grass Pollen Allergy, Hay Fever
Clinical Efficacy and Safety of gpASIT+TM to Treat Seasonal Allergic Rhinoconjunctivitis
The purpose of the study is to evaluate the efficacy and safety of grass pollen-derived peptides administrated orally to treat seasonal allergic rhinoconjunctivitis.
- Trial name
- NCT01308021
- Testing
- gpASIT+TM
- Where
- 19 sites in Belgium, France and 1 more
- Volunteers
- 202 people
- Sponsor
- BioTech Tools S.A.
Seasonal Allergic Rhinitis
Study to Assess the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Cetirizine Alone on Symptoms in Patients With Allergic Rhinitis
The aim of this study is to assess the efficacy on nasal congestion and other allergic symptoms and the onset of action of an oral combination of cetirizine and pseudoephedrine in comparison to the single substances under…
- Trial name
- NCT00334698
- Testing
- Cetirizine, Pseudoephedrine, Cetirizine with Pseudoephedrine
- Where
- Germany
- Volunteers
- 51 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Seasonal Allergic Rhinitis
Study of the Efficacy and Safety of MK-0476 in Japanese Pediatric Participants With Seasonal Allergic Rhinitis (MK-0476-519)
This study will evaluate the efficacy and safety of montelukast (MK-0476) in the treatment of Japanese pediatric participants with seasonal allergic rhinitis (SAR).
- Trial name
- NCT01857063
- Testing
- Montelukast
- Volunteers
- 220 people
- Sponsor
- Organon and Co
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