Clinical trials: Allograft
Chronic Lung Allograft Dysfunction Lung MRI (CLAD)
Chronic Lung Allograft Dysfunction MRI Study
This studies purpose is to confirm the efficacy and efficiency of using OE-MRI and MRI with hyperpolarized gas techniques and Iodinated contrast CT scan, this will enhance understanding of CLAD pathophysiology.
- Trial name
- NCT06406777
- Testing
- Spirometry, Contrast Lung Computed Tomography (CT) Scan, Oxygen enhanced magnetic resonance imaging (OE-MRI) Scan
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sean Fain
Maxillary Sinus, Allograft
Maxillary Sinus Augmentation Using CAD/CAM Allogenic Bone Blocks Versus Particulate Allogenic Grafts
28 patients will be included in this study with atrophic posterior maxillary ridge due to sinus pneumatization who will randomly assigned to two groups Group I: sinus lifting using CAD/CAM allogenic block through lateral window…
- Trial name
- NCT07604155
- Testing
- sinus lifting using CAD/CAM allogenic block, sinus lifting using particulate allogenic graft
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Tanta University
Immediate Implant Placement, Gap Filling With e-PRF
Extended Platelet Rich Fibrin Versus Allograft as Space Filling Material
Twenty-eight patients seeking prosthetic replacement of non-restorable single rooted maxillary teeth by dental implant will be selected from the outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of…
- Conditions
- Immediate Implant Placement, Gap Filling With e-PRF, Gap Filling With Allograft
- Trial name
- NCT07445776
- Testing
- Allograft, e-PRF
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Skin Graft (Allograft) Rejection, Skin Graft Complications
The Effect of Platelet Rich Plasma on Pain at Skin Graft Donor Sites
The purpose of this study is to compare post-operative skin graft donor site pain between those treated with standard wound care vs PRP. Secondarily the study is designed to compare time to complete donor site healing.
- Conditions
- Skin Graft (Allograft) Rejection, Skin Graft Complications, Skin Graft Detachment, PRP
- Trial name
- NCT03937765
- Testing
- PRP harvest and preparation
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Allograft
Efficacy of Fascia Lata Allograft and Platelet Rich Fibrin on the Periodontal Phenotype Around Dental Implant
To compare between the efficacy of fascia lata allograft and platelet rich fibrin versus subepithelial connective tissue graft on periodontal phenotype (thickness and width of keratinized tissue, labial bone thickness) around…
- Trial name
- NCT06219473
- Testing
- Fascia lata membrane, Platlet Rich fibrin membrane, subepithelial connective tissue graft
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
A-PRF, ALLOGRAFT
Sticky Bone Compared to A-PRF(Platlet Rich Fibrin) Effect on Alveolar Ridge Preservation
In this research investigators are going to detect the effect of using different type of materials(sticky bone\platlet rich fibrin ) compared to normal healing on the dimensional changes of alveolar crest after single rooted…
- Trial name
- NCT05536492
- Testing
- A-PRF, ALLOGRAFT
- Where
- Palestinian Territories
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Arab American University (Palestine)
Outcomes of Allograft
Long Term Outcomes of Osteochondral Allografts for Osteochondral Defects of the Knee
The purpose of this study is to evaluate the functional and clinical outcomes of patients receiving femoral condyle osteochondral allografts, to evaluate potential predisposing factors to failure of such grafts, and to compare…
- Trial name
- LongTermOC (NCT02308358)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Kidney; Complications, Allograft, Transplantation Infection
The Role of B Cells in Kidney Allograft Dysfunction
The purpose of this study is to understand the role of specific B cells in activating or repressing an anti-allograft immune response after kidney transplantation.
- Trial name
- NCT02294032
- Testing
- Immunosuppressive Agents
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Cardiac Allograft Vasculopathy
A P2X7R Single Nucleotide Mutation Promotes Chronic Allograft Vasculopathy
Heart transplantation (HT) is a lifesaving procedure for patients with end-stage heart failure and provides a better survival and quality of life if compared to medical treatment.
- Trial name
- NCT02082821
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Bone Diseases, Infectious, Disease of Bone
Spinal Infection Management With Structural Allograft
Background. Bone infections can involve the vertebral column, intervertebral disc space, spinal canal and soft tissues, can generate neurological deficit in addition to the destruction of the bone that causes functional…
- Conditions
- Bone Diseases, Infectious, Disease of Bone, Syndrome, Spine Infection
- Trial name
- NCT03265561
- Testing
- Bone allograft, Bone auto and allograft group
- Where
- Mexico
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Transplantation, Heart-Lung, Chronic Lung Allograft Dysfunction
Evaluation of Electrical Impedance Tomography for the Diagnosis of Chronic Rejection in Lung Transplants Recipients
Electrical impedance tomography (EIT) is non-invasive and provides functional imaging of the lung and it could be a useful tool to diagnose chronic lung allograft dysfunction (CLAD) and specially Bronchiolitis Obliterans Syndrome…
- Conditions
- Transplantation, Heart-Lung, Chronic Lung Allograft Dysfunction, Bronchiolitis Obliterans Syndrome
- Trial name
- CLAD (NCT02863835)
- Testing
- EIT, Salbutamol nebulisation and with CPAP
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Alveolar Bone Grafting, Allograft
Evaluation of Zimmer Puros® Allograft vs. Creos™ Allograft for Alveolar Ridge Preservation
The purpose of this study is to evaluate clinically, histologically and radiographically the healing of extraction sockets with Zimmer's Puros® allograft compared to creos™ (creo™ Nobel Biocare,), a low-cost allograft material…
- Conditions
- Alveolar Bone Grafting, Allograft, Dental Extraction, Dental Implant
- Trial name
- NCT02444052
- Testing
- Zimmer Puros Cancellous Allograft, Nobel Biocare Creos Cancellous Allograft
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cardiac Allograft Vasculopathy
Noninvasive Evaluation of Cardiac Allograft Vasculopathy
Abnormal peripheral endothelial function and alterations in circulating biomarkers that are associated with endothelial activation and inflammation correlate with angiographic evidence of cardiac allograft vasculopathy, defined…
- Trial name
- CAVII (NCT01305382)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota