Clinical trials: Alveolar Cleft
Alveolar Cleft Grafting
Alveolar Cleft Grafting Using Two Different Alloplastic Grafts
P-patients with unilateral alveolar clefts I-purabone with -β-tricalcium phosphate graft C-β-tricalcium phosphate graft alone O-clinical out come Outcome name Measurement device Measurement unit Esthetic satisfaction (Primary…
- Trial name
- NCT03016793
- Testing
- Puerarin, β- tricalcium phosphate, β- tricalcium phosphate alone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft of Alveolar Ridge
The Use of Self Inflating Tissue Expanders In The Treatment Of Alveolar Cleft
patient receiving treatment using the osmed expander will have enough soft tissue coverage securing the bone graft which will be placed in a later stage to close the alveolar cleft.
- Trial name
- NCT03010345
- Testing
- Osmed self inflating tissue expanders, Iliac bone graft
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nasoalveolar Fistula (Defect)
Clinical Assessment of Usage of Cleft Margin Flap With Anterior Palatal Closure in Closure of Naso-alveolar Defect.
During primary cleft lip repair in patients who were born with cleft lip and palate, usage of cleft margin flap with anterior palatal closure will be done in an attempt to close the Naso-alveolar fistula (defect) that usually…
- Trial name
- NCT03922438
- Testing
- usage of cleft margin flap with anterior palatal closure during primary cleft lip repair.
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Lip and Palate
Methods of Providing Information Prior to an Alveolar Bone Graft
Patients born with a cleft of the lip and/or palate may have a gap in the bone in the roof of their mouth and in the area of bone where the teeth develop.
- Trial name
- NCT04381078
- Testing
- ACE - AudioVisual Guide
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Alveolar Bone Grafting
Use of Particulate Cortico- Cancellous Anterior Iliac Graft with Periosteum Membrane in Unilateral Alveolar Cleft Grafting Versus Particulate Cortico-cancellous Anterior Iliac Grafting Alone.
In the past few years, periosteal membrane has been used in orthopedic surgery as well as periodontal surgery as a mechanism to promote bone healing without the ingrowth of fibrous tissues.
- Trial name
- periosteum (NCT06795919)
- Testing
- : delayed surgical repair of alveolar cleft using particulate cortico-cancellous anterior iliac bon
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nesma Mattar
Alveolar Cleft
Double Closure of Nasal Layer in Alveolar Cleft Grafting
The aim of this prospective study is to evaluate both clinically and radiologically the efficacy of using autologous platelets rich fibrin versus collagen membrane for nasal layer closure in secondary alveolar cleft repair.
- Trial name
- NCT05988086
- Testing
- platelet rich fibrin, collagen membrane
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanta University
Alveolar Bone Grafting, Quality of Life
Effect of Alveolar Bone Grafting
This study included patients who underwent secondary alveolar bone grafting by harvesting graft from the anterior iliac crest, in Oral and Maxillofacial Department, Faculty of Dentistry, Ankara University, Turkey, during the…
- Trial name
- NCT03549039
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ankara University
Alveolar Cleft
Evaluation of Secondary Alveolar Cleft Reconstruction
The rehabilitation of the disorganized maxilla is the primary objective of secondary alveolar bone grafting (SABG) for alveolar clefts, as the bony reconstruction of the discontinued maxillary arch would permit proper anterior…
- Trial name
- NCT06621719
- Testing
- Alveolar Cleft Reconstruction
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Alveolar Cleft
Partial Maxillary Expansion With Post Grafting Expansion vs. Pre Full Maxillary Expansion in Secondary Alveolar Cleft
Intermediate grafting with both pre- and post- grafting maxillary expansion with time span after grafting 6-8 weeks for consolidation and final retention for 3 months after finalization of expansion will get the advantages of…
- Trial name
- NCT05941988
- Testing
- pre grafting partial maxillary expansion with post grafting expansion
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bilateral Complete Cleft Lip And/or Alveolus and Acrylic Splint, and, Maxillary Deficiency
Evaluating the Impact of Prefabricated Acrylic Splints on Premaxillary Stability in Alveolar Cleft Bone Graft Repairs: a Randomized Controlled Trial
Rationale for conducting the research: Bilateral alveolar clefts pose significant management challenges, with current treatments like autogenous bone grafting showing instability in up to 40% of cases within a year, risking graft…
- Conditions
- Bilateral Complete Cleft Lip And/or Alveolus and Acrylic Splint, and, Maxillary Deficiency, Stability
- Trial name
- RCT (NCT06807645)
- Testing
- Clinical Trial Intervention Description General Study Setup Objective: To compare the efficacy of using a custom-made prefabricated acrylic splint versus no splint in maintaining premaxillary stabilit
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Unilateral Cleft Lip
The Effect of Use of Dermal Fat Graft as a Barrier Membrane
a study conducted to assess the use of dermal fat graft use as barrier membrane over grafted bone
- Trial name
- NCT05334602
- Testing
- Addition of dermal fat graft as protection over bone graft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cleft Lip and/or Palate, Cleft Lip Bilateral
Conventional Versus Modified Pre-surgical Naso-Alveolar Molding Treatment in Cleft Lip and Palate Infants
The aim of this study is to evaluate and compare clinically conventional Pre-surgical Naso-Alveolar Molding (PNAM) treatment versus Modified Naso-Alveolar Molding protocol (MPNAM) in cleft lip and palate patients in terms of: 1.
- Trial name
- NCT06494098
- Testing
- Nasoalveolar Molding, Addition silicone impression
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Cleft
Evaluation of Autogenous Tooth- Derived Graft With Bovine Bone For Surgical Repair of Unilateral Alveolar Cleft
The aim of this study is evaluation of autogenous tooth-derived graft combined with bovine bone for surgical repair of unilateral alveolar cleft .
- Trial name
- NCT06855875
- Testing
- autogenous tooth graft combined with bovine bone, bovine bone
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cleft Lip and Palate
Bone Tissue Engineering With Dental Pulp Stem Cells for Alveolar Cleft Repair
Iliac crest autogenous bone graft is accepted as the most effective method for secondary alveolar cleft repair. However this method is associated with complications.
- Trial name
- CLOSE (NCT03766217)
- Testing
- Mesenchymal stem cells associated with biomaterials, Iliac crest autogenous bone graft
- Where
- Brazil
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hospital Sirio-Libanes
Alveolar Cleft
Assessment of Nanocrystalline Hydroxyapatite Versus Autogenous Bone Grafts : A Comparative Clinical Study in Alveolar Cleft Grafting
This work aims to evaluate Nanocrystalline Hydroxyapatite versus Autogenous bone grafts in alveolar cleft grafting
- Trial name
- NCT04693559
- Testing
- secondary alveolar bone graft, harvesting of the autogenous bone graft, Nanocrystalline Hydroxyapatite
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cleft Palate
Effect of Cleft Palate Repair Using Alveolar Extension Technique on Eruption and Growth
This study aimed to evaluate clinically the "Alveolar extension" technique for palatoplasty in cases of primary closure of cleft palate regarding its effect on: 1. Eruption of Primary dentition. 2.
- Trial name
- NCT05286398
- Testing
- Palatoplasty, Addition silicone impression
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cleft Lip and Palate
Alveolar Cleft Hard- and Soft Tissue Reconstruction With an Autogenous Tooth Derived Particulate Graft
The present study aims at clinical and radiographic evaluation of the safety and efficacy of Bonmaker ATB powder combined with a novel split thickness papilla curtain flap in the treatment of alveolar cleft defects.
- Trial name
- NCT05971914
- Testing
- Autogenous tooth derived particulate graft and a novel split thickness papilla curtain flap
- Where
- Hungary
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Cleft Lip and Palate, Unilateral Cleft Lip
Influence of Presurgical Orthodontic Molding on the Growth of Newborns With Unilateral Cleft Lip Palate
Orofacial clefts are the second most common birth deformity and vary in etiology and phenotype, e.g. isolated cleft palate, cleft lip or cleft lip palate.
- Trial name
- NCT05081258
- Testing
- passive Alveolar Molding, Nasoalveolar Molding
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg
Cleft Lip and Palate, Rhinoplasty
Single Stage Versus Multiple Staged Repair of Nasal & Alveolar Deformities in Patients With Cleft Lip and Palate
Cleft lip and palate patients are commonly seen among maxillofacial patients. Patients with cleft lip and palate have evident cosmetic nasal deformities.
- Trial name
- NCT06510881
- Testing
- Rhinoplasty with or without cleft alveolus repair
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Alveolar Cleft
Alveolar Cleft Grafting by Double Iliac Bone Blocks Versus Iliac Spongy Bone From Anterior Iliac Crest
Reconstruction of Alveolar Cleft Using Double Iliac Corticocancellous Blocks in comparison with the gold standard technique ( cancellous bone ) both from anterior iliac crest.
- Trial name
- NCT05283005
- Testing
- Grafting of the alveolar cleft
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University