Clinical trials: Alveolar Process Atrophy, open to volunteers
Tooth Extraction, Tooth Extraction Site Healing
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether β-TCP (Beta-Tricalcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Conditions
- Tooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- BTCPARPBV (NCT07638319)
- Testing
- Neocement Inject P® (Beta-Tricalcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Alveolar Bone Loss
VST vs Modified Periosteal Inhibition Technique
Losing a tooth in the upper front of the mouth is common, and many people choose a dental implant to replace it. When a tooth is removed, the thin layer of bone in front of the socket - the buccal, or front, bone - often shrinks…
- Trial name
- VST (NCT07784764)
- Testing
- VST, Mucoperiosteal inhibition
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tanta University
Laser Therapy, Periodontal Diseases
Odontogenic Graft Obtained From Human Tooth and Low Level Laser Therapy
This clinical trial aims to evaluate the effectiveness of an odontogenic graft obtained from extracted human teeth, with and without adjunctive low-level laser therapy (LLLT), on bone regeneration following posterior tooth…
- Conditions
- Laser Therapy, Periodontal Diseases, Bone Loss in Jaw, Alveolar Bone Loss
- Trial name
- NCT07615361
- Testing
- Autogenous Tooth-Derived Bone Graft, Low-Level Laser Therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Alveolar Bone Loss, Maxillary Sinus Disease
Efficacy of Bioactive Glass vs. Xenograft in Maxillary Sinus Augmentation
This randomized controlled study aims to evaluate the clinical, radiographic, and histologic efficacy of using bioactive glass bone graft (UNIGRAFT by Biomed Inc., USA) compared to a conventional xenograft in maxillary sinus…
- Conditions
- Alveolar Bone Loss, Maxillary Sinus Disease, Tooth Loss
- Trial name
- BIOXENO (NCT07125846)
- Testing
- Bioactive Glass Bone Graft (UNIGRAFT), Xenograft Bone Graft (Bio-Oss)
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Alveolar Bone Loss, Sinus Floor Augmentation
Impact of Alveolar Ridge Preservation on the Potential Need for Sinus Floor Elevation: A 10-year Retrospective Radiographical Study
This research aims to investigate the influence of alveolar ridge preservation, after extraction of maxillary posterior teeth, on the potential need of sinus floor augmentation procedures (that include lateral or crestal sinus…
- Conditions
- Alveolar Bone Loss, Sinus Floor Augmentation, Sinus Pneumatization, Alveolar Bone Atrophy
- Trial name
- NCT07526129
- Testing
- Alveolar ridge preservation using bony biomaterials
- Where
- Lebanon
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Alveolar Bone Loss, Alveolar Ridge Deficiency
Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation Using Customized Porous Zirconia Shell
The goal of this clinical study is to learn whether a custom-made porous zirconia shell can support good-quality new bone when widening the lower back jaw before dental implant placement.
- Trial name
- NCT07841158
- Testing
- Customized porous zirconia shell
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Mohammed Mahmoud Abed
Periodontal Diseases, Hyperuricemia
Evaluation of the Effect of Hyperuricemia on Alveolar Bone Loss
Periodontitis is a multifactorial disease characterized by chronic inflammation of the gum tissue and alveolar bone destruction, and is known to be associated with various systemic diseases.
- Conditions
- Periodontal Diseases, Hyperuricemia, Oxidative Stress
- Trial name
- NCT07666126
- Testing
- Collection of gingival crevicular fluid (GCF) and serum samples, Measurement of periodontal clinical parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Alveolar Bone Loss, Dental Implant
Socket Preservation - A Randomized Clinical Implementation in a Student Setting
Preserving the ridge dimension after tooth extraction aims to avoid the need for bone augmentation procedures before implant placement.
- Conditions
- Alveolar Bone Loss, Dental Implant, Bone Augmentation
- Trial name
- NCT06539299
- Testing
- Socket Preservation
- Volunteers
- 51 people
- Sponsor
- Sigmund Freud PrivatUniversitat
Alveolar Bone Loss, Alveolar Ridge Augmentation
Evaluation of Guided Tissue Regeneration With Autogenous Bone Chips and CGF During Implant Placement
CGF membranes will be prepared using a swing-lock centrifuge. A full-thickness mucoperiosteal flap will be elevated in a narrow alveolar ridge. Implants will be inserted.
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Augmentation, Dental Implant
- Trial name
- CGF (NCT07521514)
- Testing
- concentrated growth factor (CGF) Membrane
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Cairo University
Bone Loss, Osteoclastic, Bone Loss, Alveolar
Autogenous Mesenchymal Stem Cell Culture-Derived Signalling Molecules as Enhancers of Bone Formation in Bone Grafting
This study aims to evaluate bone formation in grafts in terms of its quality (density), quantity (volume) and maturation obtained with the application of a tissue-engineered bone grafting compound containing concentrated…
- Conditions
- Bone Loss, Osteoclastic, Bone Loss, Alveolar, Alveolar Bone Loss, Alveolar Bone Atrophy
- Trial name
- NCT04998058
- Testing
- Maxillary sinus floor elevation grafting with synthetic bone substitute.
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Alveolar Bone Loss, Sinus Floor Augmentation
Two Bovine Xenografts in Lateral Window Sinus Augmentation With or Without Bone Marrow Blood
The goal of this clinical trial is to learn whether adding a small amount of blood taken from the jawbone marrow improves new bone formation when two different bone graft materials are used in maxillary sinus lift surgery.
- Conditions
- Alveolar Bone Loss, Sinus Floor Augmentation, Edentulous Alveolar Ridge
- Trial name
- NCT07904065
- Testing
- Deproteinized Bovine Bone Mineral (Bio-Oss), Deproteinized Bovine Bone Mineral (InterOss), Mandibular Bone Marrow Blood Aspiration
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad del Desarrollo
Intrabony Defect, Periodontal Diseases
RGD With Minimally Invasive Non-Surgical Technique in Treatment of Periodontal Intrabony Defect
Periodontal regeneration is a complex process that involves coordinated activities and interactions of many cell types, extracellular matrix, cytokines, and specific growth factors to restore tissue integrity.
- Conditions
- Intrabony Defect, Periodontal Diseases, Alveolar Bone Loss
- Trial name
- MINST + RGD (NCT06936605)
- Testing
- RGD Peptide
- Volunteers
- 45 people
- Sponsor
- Minia University
Alveolar Ridge Preservation, Horizontal Alveolar Bone Loss
Radiographic and Histomorphometric Assessment for Alveolar Ridge Preservation Using Autogenous Tooth Graft From Extracted Tooth Combined With Simvastatin 1:1 Versus Autogenous Tooth Graft
This study will be held to overcome the previous limitations related to bone loss after teeth extraction by taking advantages from both Autogenous tooth graft and Simvastatin which will offer a promising synergistic approach for…
- Conditions
- Alveolar Ridge Preservation, Horizontal Alveolar Bone Loss, Vertical Alveolar Bone Loss, Delayed Implant
- Trial name
- ARP (NCT06879171)
- Testing
- Alveolar ridge preservation
- Volunteers
- 26 people
- Sponsor
- Cairo University
Alveolar Bone Loss, Esthetic Zone Implant Rehabilitation
Immediate Implant Placement With Autogenous Maxillary Tuberosity Graft in the Esthetic Zone
Immediate implant placement in the esthetic zone is often associated with buccal bone deficiency, which may compromise esthetic outcomes and long-term implant stability.
- Trial name
- TUBERO-IMPLANT (NCT07460076)
- Testing
- Immediate Implant Placement With Maxillary Tuberosity Autogenous Graft
- Where
- Vietnam
- Volunteers
- 15 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Alveolar Bone Atrophy, Guided Bone Regeneration
Efficacy and Safety of Additive Manufacturing Personalized Titanium Mesh in Guided Bone Regeneration
This goal of this single-blind, simple randomized, positive-controlled prospective study is to evaluate the effects of additive-manufactured personalized titanium mesh and traditional titanium mesh in guided bone regeneration for…
- Trial name
- NCT06692244
- Testing
- Guided Bone Regeneration Surgery Using Additive-Manufactured Personalized Titanium Mesh, Guided Bone Regeneration Surgery Using Prefabricated Titanium Mesh
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Hospital of Stomatology, Sun Yat-Sen University
Atrophy of Edentulous Maxillary Alveolar Ridge, Alveolar Bone Atrophy
Morphological Characteristics of Anterior Maxillary Bone and Dynamic Navigation in Full-Arch Implant Placement
The goal of this clinical trial is to evaluate the effectiveness of dynamic navigation in full-arch dental implant placement in patients with complete maxillary edentulism.
- Trial name
- NCT06974253
- Testing
- Nasopalatine Implants, Trans-Sinus Implants, and Trans-Nasal Implants for Full-Arch Rehabilitation
- Where
- Vietnam
- Volunteers
- 20 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Periodontal Bone Loss, Periodontal Defect
Polynucleotides and Hyaluronic Acid vs Enamel Matrix Proteins in the Treatment of Intrabony Defects
The goal of this clinical trial is to compare two periodontal regenerative treatments in adults with Stage III or IV periodontitis and infrabony periodontal defects ≥3 mm.
- Conditions
- Periodontal Bone Loss, Periodontal Defect, Periodontitis Stage III, Periodontitis Stage IV
- Trial name
- PN-HAVSEMPIND (NCT07589959)
- Testing
- Regenerative periodontal surgery using Regenfast® (hyaluronic acid + polynucleotides) with Bio-Oss® graft, Regenerative periodontal surgery using Emdogain® (enamel matrix derivative) with Bio-Oss® graft
- Volunteers
- 40 people
- Sponsor
- Shashi Dadlani
Tooth Loss / Rehabilitation, Tooth Extraction
Ovate Pontic Versus Essix Provisional After Tooth Extraction and Alveolar Ridge Preservation (Pontic-Essix)
This randomized controlled trial compares two provisional socket-sealing concepts following single non-molar tooth extraction and alveolar ridge preservation: a fixed, tooth-supported, 3D-printed ovate pontic provisional…
- Conditions
- Tooth Loss / Rehabilitation, Tooth Extraction, Alveolar Bone Loss, Alveolar Ridge Augmentation
- Trial name
- Pontic-Essix (NCT07748871)
- Testing
- Bio-Oss Collagen, Mucograft Seal, Fixed 3D-printed ovate pontic provisional restoration
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Bern
Bone Loss, Bone Loss, Age-related
Minimally Invasive Sinus Lift Through the Interradicular Septum
This study aims to describe a new approach for the reconstruction of the alveolar process in the sinus area. This minimally invasive approach will access the maxillary sinus through the alveolar process, elevating the sinus…
- Conditions
- Bone Loss, Bone Loss, Age-related, Atrophy; Alveolar Process, Surgical Procedure, Unspecified
- Trial name
- NCT05237570
- Testing
- Interradicular septum window
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Murcia
Periodontal Diseases, Periodontal Bone Loss
3D Printed Customized Bone Graft for Alveolar Regeneration: Longitudinal Cohort Evaluation
This study will evaluate the behavior of the implant-supported restorations (prosthesis) placed into the areas grafted with the 3D printed customized bone (personalized graft produced to fit a specific bone defect), as well as…
- Trial name
- NCT07405918
- Testing
- Clinical evaluation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos