Clinical trials: Ambulation Disorder, Neurologic
Spinal Cord Injury, Spinal Cord Injury Subacute
Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury
Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (< 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to…
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Subacute, Locomotion, Gait Disorder, Sensorimotor
- Trial name
- CIMELocomotion (NCT07375745)
- Testing
- Protocol 2: Gait training combined with an effective tSCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Down Syndrome
Treadmill Training and Orthotic Use in Infants With Down Syndrome
This study determines the effect of orthotic use in combination with treadmill training on the development of gross motor skills and walking onset in infants with Down syndrome.
- Trial name
- NCT00825175
- Testing
- Treadmill Training, Supramalleolar Orthoses
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Stroke
Characteristics of Balance Control to Unexpected Loss of Balance During Standing and Walking in Post-stroke Individuals
aim: To examine the effect of a perturbation-based balance training on balance reaction characteristics in post stroke individuals.
- Trial name
- NCT02619175
- Testing
- Stroke Subjects Perturbation-Based Balance Training, Stroke Subjects Weight Shifting and Gait training
- Where
- Israel
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nachum Soroker, MD
Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Relapsing-Remitting
Exercise Effects in Multiple Sclerosis
A growing body of work suggests that regular exercise can support symptom management and improve physical function for people living with multiple sclerosis (MS).
- Conditions
- Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Secondary Progressive, Multiple Sclerosis, Chronic Progressive
- Trial name
- NCT05496881
- Testing
- Exercise Group 1, Exercise Group 2, Exercise Group 3
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- University of Regina
Cerebrovascular Accident
Videographic Feedback and Walk Rehabilitation in Post-Cerebrovascular Accident
Cerebrovascular Accident affects the majority of the elderly population and its frequency is constantly increasing. The resulting deficits are numerous and lead in particular to an alteration in the quality of walking and…
- Trial name
- CoDévi (NCT05024981)
- Testing
- Videographic feedback, Classic reeducation
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Stroke
Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal
Achieving functional ambulation post stroke continues to be a challenge for stroke survivors, clinicians, and researchers. In the effort to enhance outcomes of motor training, cortical priming using brain stimulation has emerged…
- Trial name
- NCT04477330
- Testing
- Transcranial direct current stimulation (tDCS), Ankle motor training, High intensity interval speed based treadmill training (HIISTT)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Illinois Chicago
Parkinson Disease
Digital Wearable Walking Aid for Freezing of Gait in Parkinson´s Disease
The objective of this study is to investigate the effects of relatively long-term use of a wearable device that provides personalized and intelligent cues (e.g. only when FOG is detected) on FOG.
- Trial name
- NCT03978507
- Testing
- Intelligent cueing, Feedback about the number of steps
- Where
- 2 sites in Belgium, Israel
- Volunteers
- 62 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Spinal Cord Injuries, Brown Sequard
Effects of Breathing and Walking Treatments on Recovery Post-Spinal Cord Injury
Change to Reflect What Was Done and reason Changes Were Made. The purpose of this study is to determine (1) if a specific breathing treatment (intermittent hypoxia) can promote changes in breathing function and (2) if pairing…
- Conditions
- Spinal Cord Injuries, Brown Sequard, Central Cord Syndrome
- Trial name
- NCT01272011
- Testing
- Intermittent Hypoxia, Locomotor Training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- VA Office of Research and Development
Multiple Sclerosis
Patient Centered Outcomes Analysis for MS Using a Mobile Application
Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) that can impact all aspects of nervous system function.
- Trial name
- NCT04281160
- Testing
- BeCare Mobile App
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BeCare Link LLC
Stroke
Comparison of Dual-Task Timed Up and Go Test (Cognitive) and 3-m Backwards Walk Test
Two balance assessment tools that have been used recently have attracted considerable attention: the Dual-Task Timed Up and Go Test (cognitive) (DTUG) and the 3-m Backward Walk Test (3MBWT).
- Trial name
- NCT05211349
- Testing
- Dual-Task Timed Up and Go Test (cognitive), 3-m Backward Walk Test, Modified Four Square Step Test
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Neurological Diseases or Conditions
Rebound Exercise in Neurological Disorders
This study will be a pretest-posttest interventional trial investigating the use of rebound exercise in community-dwelling individuals with neurological disorders.
- Trial name
- NCT05526508
- Testing
- Rebound exercise
- Where
- 2 sites in United Kingdom
- Volunteers
- 52 people
- Sponsor
- Buckinghamshire New University
Spinal Cord Injury
Combination Therapy With Dalfampridine and Locomotor Training for Chronic, Motor Incomplete Spinal Cord Injury
The purpose of this study is to determine the efficacy, safety, and tolerability of treatment with dalfampridine in combination with locomotor training in persons with chronic, motor incomplete SCI.
- Trial name
- NCT01621113
- Testing
- Dalfampridine
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Kessler Foundation
Cerebral Palsy
The Effect of a Comprehensive Rehabilitation Program Using Robotic Walking and Functional Electrical Stimulation Technologies on Balance and Walking in Children With Cerebral Palsy
The aim of this study was to investigate the effect of a comprehensive rehabilitation program using robotic walking and functional electrical stimulation technologies on balance and gait in children with cerebral palsy.
- Trial name
- NCT06403891
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara City Hospital Bilkent
Multiple Sclerosis
FES: Effect on Walking in the Real World and Participation in Daily Life in People With Multiple Sclerosis.
Multiple sclerosis (MS) is a chronic, neurodegenerative disease and the most common cause of non- traumatic disability in young adults.
- Trial name
- FES in MS (NCT07706114)
- Testing
- Use of functional electrical stimulation for extended duration on the participants' weaker limb
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Francisco
Cerebral Palsy
Ischemic Conditioning to Enhance Function (I-C-FUN) in Children With Cerebral Palsy
The purpose of this research study is to determine if remote limb ischemic conditioning (RLIC) can increase skeletal muscle power, enhance learning of motor (dynamic balance) task, and improve walking performance in children with…
- Trial name
- I-C-FUN (NCT04598711)
- Testing
- RLIC, Muscle Power training, Balance training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- East Carolina University
Neuropathic Pain
Virtual Walking and Neuromulation to Reduce Neuropathic Pain After a Spinal Cord Injury
The goal of this single-subject design is to evaluate an intervention combining neuromodulation, virtual reality, and muscle vibration to reduce neuropathic pain in individuals following a spinal cord injury.
- Trial name
- NCT07254767
- Testing
- Transcranial Direct Current Stimulation (tDCS) combined with virtual reality and muscle vibration
- Volunteers
- 10 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Stroke, CVA (Cerebrovascular Accident)
Cognition and Motor Learning Post-stroke
This project seeks to determine how post-stroke cognitive impairment moderates motor learning during walking in older adults with chronic stroke and identify brain structural markers that mediate this relationship.
- Trial name
- NCT04829071
- Testing
- Explicit motor learning, Implicit motor learning
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Southern California
Spinal Cord Injuries
Recovery of Walking in Persons With Complete Spinal Cord Injury
We documented the impact of 1 year of underwater treadmill training and supplemental overground walk training in five adults with chronic motor-complete SCI (cSCI) who had not undergone programmed epidural spinal cord stimulation…
- Trial name
- NCT04237363
- Testing
- Exercise
- Volunteers
- 5 people
- Sponsor
- Middle Tennessee State University
Spinal Cord Injuries (SCI)
VR-Integrated C-Mill® Combined With Conventional Therapy in Motor-Incomplete SCI
This study investigates the effects of C-Mill® treadmill training, which integrates virtual reality and gamified tasks, combined with conventional physiotherapy, on walking ability, mobility, functional independence, and…
- Trial name
- NCT07141784
- Testing
- C-Mill® Treadmill Training Combined with Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people
- Sponsor
- Ankara City Hospital Bilkent
Stroke, Cerebrovascular Disease
Functional Changes and Home Discharge After Inpatient Stroke Rehabilitation
This retrospective observational study will evaluate whether changes in functional status during inpatient rehabilitation are associated with discharge destination in patients with stroke treated at a post-acute rehabilitation…
- Trial name
- NCT07502326
- Testing
- Inpatient Rehabilitation
- Where
- South Korea
- Volunteers
- 119 people
- Sponsor
- SeongKi Min
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