Clinical trials: Ambulation Disorder, Neurologic
Parkinson's Disease
Ambulosono Rasagiline Musical Walking Study
This study will investigate the effects of a contingency-based musical walking intervention program called Ambulosono on neural mechanisms in the brain.
- Trial name
- NCT02207387
- Testing
- Azilect, Exercise, Music
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Parkinson Disease, Parkinson Disease 10
Effects of Nordic Walking in Parkinson Disease Patients
The aim of this study was to evaluate and compare the effects of a Nordic and free walking training program on clinical, functional and biomechanical parameters of gait, in people with PD.
- Trial name
- Walking (NCT03355521)
- Testing
- Nordic Walking, Free Walking
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Federal University of Rio Grande do Sul
Walking Impairment, Multiple Sclerosis
Safety and Efficacy of ADS-5102 in Patients With Multiple Sclerosis and Walking Impairment
This is a multi-center, randomized, double-blind, placebo-controlled, 2-arm, parallel group study of ADS-5102 extended release (ER) capsules, an investigational formulation of amantadine, dosed once daily at bedtime for the…
- Trial name
- NCT02471222
- Testing
- ADS-5102
- Where
- 15 sites in United States
- Volunteers
- 60 people
- Sponsor
- Adamas Pharmaceuticals, Inc.
Crouch Gait, Cerebral Palsy (CP)
Robotic Knee Orthosis-assisted Walking in CP
Robotic exoskeletons are becoming increasingly accepted to provide upright mobility in individuals with neurological disorders. These devices can assist in overcoming gravitational forces and reduce energy consumption.
- Trial name
- NCT06887764
- Testing
- RKO-assisted walking in individuals with CP
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hospital for Special Surgery, New York
Parkinson Disease
Effects of Nordic Walking and Free Walking on Arm Swing Parameters and Gait in Parkinson's Disease
People with Parkinson's Disease(PD) present a series of alterations such as muscle stiffness and motor slowing, which gradually affect the swinging movement of the arms and legs, altering the ability to walk, increasing the risk…
- Trial name
- NCT06342271
- Testing
- Nordic walking training, Free Walking training
- Volunteers
- 28 people
- Sponsor
- University of Talca
Fall Injury, Walking, Difficulty
Attentional Focus Instructions and Conscious Movement Processing in Older Adults
This study aims to provide a novel scientific contribution through addressing critical knowledge gaps, examining the effects of attentional focus instructions on real-time (state) conscious movement processing propensity, gait…
- Conditions
- Fall Injury, Walking, Difficulty, Gait, Unsteady
- Trial name
- NCT05411536
- Testing
- Walking trials
- Where
- China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Obesity & Overweight, Headache
Investigation of the Relationship Between Gray and White Matter Volumes, Walking Exercise, and Body Fat Percentage in Adults With a Body Mass Index Above 25
This study examines the relationship between walking exercise, body fat percentage changes, and brain gray and white matter volumes in overweight and obese adults with headache complaints.
- Conditions
- Obesity & Overweight, Headache, Sedentary Lifestyle, Body Fat Percentage
- Trial name
- NCT07425093
- Testing
- Walking Exercise Program, Dietary Intervention, Brain MRI Morphometry
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Amasya University
Multiple Sclerosis, Poststroke/CVA Hemiparesis
Efficacy of Split Gait in the Treatment of Dynamic Asymmetries in Subjects With Pathologic Claudication
Walking on a split-belt treadmill (each of the two belts running at a different speed) imposes an asymmetrical gait, mimicking limping that has been observed in various pathologic conditions.
- Conditions
- Multiple Sclerosis, Poststroke/CVA Hemiparesis, Parkinson Disease, Amputation
- Trial name
- ESPLICA (NCT04635436)
- Testing
- Split-belt treadmill walking.
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Auxologico Italiano
Stroke
Effects of rTMS Combined With Dual-Task Gait Training on Walking and Cognition After Stroke
This randomized, double-blind, placebo-controlled trial will investigate whether repetitive transcranial magnetic stimulation (rTMS) applied to the dorsolateral prefrontal cortex (DLPFC) can enhance the effects of dual-task gait…
- Trial name
- NCT07356687
- Testing
- active rTMS with dual-task training
- Where
- Hong Kong
- Volunteers
- 184 people
- Sponsor
- The Hong Kong Polytechnic University
Healthy, Thalamic Pain Syndrome
Gait Parameters Analysis in Post-stroke Patients and in Elderly Fallers
A large proportion of falls in older people occurs when walking. Most studies have recently demonstrated correlation between the variations in spatiotemporal gait parameters and fall risk in elderly and in several diseases.
- Conditions
- Healthy, Thalamic Pain Syndrome, Fallers
- Trial name
- GAITRITE (NCT01443052)
- Testing
- Gait analysis
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Joint Pain, Trouble Balancing
Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots
Patients who undergo foot and ankle surgery are often made weight-bearing as tolerated (WBAT) in a controlled ankle movement (CAM) boot during their recovery and rehabilitation process.
- Trial name
- NCT03848949
- Testing
- Evenup
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Rush University Medical Center
Stroke, Ischemic, Cerebrovascular Accident
Effects of High-intensity Interval Aerobic Training on Balance, Walking Capacity, and Quality of Life in Patients With Sub-acute Stroke
Hemiplegia is one of the most common sequelae of stroke. Stroke is the leading cause of disability in adults all around the world.
- Trial name
- NCT04835740
- Testing
- High intensity Interval Training
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Akhtar Saeed Medical and Dental College
Stroke
Effects of Power and High-Intensity Gait Training for Functional Mobility an Ambulation in Chronic Stroke
This randomized controlled trial aims to determine the combined effect of power training and high-intensity gait training on functional mobility and locomotion following chronic stroke.
- Trial name
- NCT07249658
- Testing
- power training + high-intensity gait training, power training, high-intensity gait training
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Stroke, Depression
Post-Stroke Optimization of Walking Using Explosive Resistance
The investigators will study the effects of a 12 week strength training program on individuals who have had a stroke and are depressed to see if this type of exercise training helps treat depression and improves walking function.
- Trial name
- POWER-D (NCT03826771)
- Testing
- Power training, Stretching
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Medical University of South Carolina
Traumatic Brain Injury
Study to Improve Ambulation in Individuals With TBI Using Virtual Reality -Based Treadmill Training
The purpose of this research study is to test the effectiveness of virtual reality (VR) based treadmill training on walking ability.
- Trial name
- NCT05130658
- Testing
- Virtual reality treadmill training, Treadmill Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Multiple Sclerosis, Healthy Controls Group - Age and Sex-matched
Measurement Properties of the Walking Adaptability Ladder Test and Foot Tap Test in Multiple Sclerosis
Walking and motor control impairments are among the most common manifestations experienced by people with multiple sclerosis (pwMS) and may already be present in individuals with mild disability.
- Trial name
- NCT07505355
- Where
- 4 sites in Belgium, Italy and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Lower Limb Spasticity
Trial to Test the Effectiveness of Vibrotactile Stimulation for Lower Limb Spasticity
The goal of this clinical trial is to find out if Vibrotactile Stimulation (VTS) can help improve mobility and reduce spasticity (muscle stiffness) in people with lower limb spasticity.
- Trial name
- NCT07447934
- Testing
- Vibrotactile Stimulation (Static Use), Vibrotactile Stimulation (Dynamic Use), Vibrotactile Stimulation (Neurophysiological Mechanism)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Weill Medical College of Cornell University
Parkinson Disease
Effects of Walking and Respiratory Muscle Training on Pulmonary Function and Functional Exercise Capacity in PD
The purpose of this randomised and controlled study is to investigate the effects of walking training combined with respiratory muscle training on pulmonary function, respiratory muscle strength, and functional exercise capacity.
- Trial name
- NCT04834258
- Testing
- Walking and respiratory training, Respiratory muscle training
- Volunteers
- 30 people
- Sponsor
- Marmara University
Freezing of Gate, Parkinson Disease
Effectiveness of Botulinum Toxin in Freezing of Gate in Parkinson's Disease Walking in Parkinson's Disease.
Freezing of gait is a symptom of Parkinson's disease (PD) that becomes more evident with the evolution of the disease, and which presents an important difference compared to the other signs and symptoms: does not respond…
- Conditions
- Freezing of Gate, Parkinson Disease, Botulinum Toxin
- Trial name
- NCT06094309
- Testing
- Botulinum toxin type A injection
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Centro Hospitalar de Lisboa Central
Fibromyalgia, Foot Core
Foot Core Intervention for Fibromyalgia
This quasi-experimental study was designed to evaluate the effects of an eight-week foot core training program on foot pain, foot function, and pressure pain sensitivity in individuals with fibromyalgia.
- Trial name
- FOOTCORE-FM (NCT07388199)
- Testing
- Foot Core
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Valencia
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