Clinical trials: Ambulation Disorder, Neurologic
Arthritis, Asthma
Mobility Assessment in Multi-morbidity
Multimorbidity (the presence of two or more coexisting long-term conditions) is a significant challenge facing the NHS, especially given UK's ageing population and the association with high levels of illness burden and healthcare…
- Conditions
- Arthritis, Asthma, Atrial Fibrillation, Bronchiectasis
- Trial name
- Multi-mobility (NCT06473168)
- Volunteers
- 55 people
- Sponsor
- Northumbria University
Parkinson Disease
Efficacy of Brisk Walking in Parkinson's Disease
Parkinson's disease (PD) is the second most common neuro-degenerative disease in older people. Falls are common among people PD with the incidence rate up to 70% and have strong associations with the severity of the disease…
- Trial name
- NCT04048291
- Testing
- Brisk walking and balance training, Upper limb exercise
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
4-point vs 4-roll Canne as Walking Aids After Stroke
Stroke patients frequently necessitate walking aids such as 4-point canne. However, the 4-point canne has to be lifted by the patient which limited gait speed.
- Trial name
- 4roll (NCT02279069)
- Testing
- 4-roll canne
- Where
- Belgium
- Volunteers
- 32 people
- Sponsor
- University Hospital of Mont-Godinne
Gait, Unsteady
Virtual Reality Training for Walking Improvement in the Elderly
Safe walking needs the older adult to anticipate and respond quickly to external demands and sudden environmental changes. The practice of complex and challenging situations of the usual daily walking is very important to prevent…
- Trial name
- NCT05623462
- Testing
- The C-Mill virtual reality treadmill, Conventional Physical Therapy Program
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Orthopedic Equine Varus Deformity
Talonavicular Arthrodesis and Surgical Treatment of Ankle and Varus Foot
This study should refine our surgical indications and to establish a decision tree of medical and surgical treatment of this common and troublesome strain functionally which is equino-varus.
- Trial name
- talobot (NCT02790346)
- Testing
- arthrodesis talonavicular, tendon gestures
- Where
- France
- Volunteers
- 33 people
- Sponsor
- University Hospital, Montpellier
Multiple Sclerosis
FAME - Fampyra Outcome Measures Study: a Study of Different Outcome Measures on the Effect of Fampyra
Fampridine-SR is registered for the treatment of walking incapacity in MS patients. Two pivotal trials show that app. 40% of MS patients with walking incapacity can improve walking speed averagely 25% when recieving the drug.
- Trial name
- FAME (NCT01656148)
- Testing
- Fampridine-SR
- Where
- 4 sites in Denmark
- Volunteers
- 108 people
- Sponsor
- University of Southern Denmark
Hemianopsia, Homonymous Hemianopia
Feasibility Test of Virtual Reality Obstacle Detection for Low Vision Walking
The investigators are developing a new test of pedestrian hazard detection in virtual reality (VR) head-mounted display (HMD) headset, which shows virtual oncoming pedestrians in 3D while subjects are walking in real-world…
- Conditions
- Hemianopsia, Homonymous Hemianopia, Tunnel Vision, Visual Field Defect, Peripheral
- Trial name
- NCT05141604
- Testing
- Field expansion view
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Parkinson Disease
Effect of Multimodal Exercise Training on Walking Economy in Individuals With Parkinson's Disease
Sustained ambulation is a challenge for individuals with Parkinson's disease (PD) as walking economy is frequently compromised. There are also various disease-related skeletal muscle alterations that may contribute to performance…
- Trial name
- NCT03864393
- Testing
- Multimodal overground locomotor training
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- George Mason University
Stroke, Cerebrovascular
Effects of Dual Task-Oriented Circuit Training on Walking Recovery in Sub-acute Stroke
This pilot study aims to assess the feasibility, safety, and initial efficacy of an integrated Dual Task-Oriented Circuit Training (DTOCT) program for individuals in the subacute phase of stroke recovery.
- Trial name
- DTOCT-Stroke (NCT07494357)
- Testing
- Dual task oriented circuit training, Task Oriented Circuit Training, Dual task training
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- Universitas Padjadjaran
Alzheimers Disease, Mild Cognitive Impairment
Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease
In people with Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), reduced capacity for locomotor adaptation is a fundamental but poorly understood mechanism that can be a sensitive biomarker of cognitive-motor…
- Trial name
- NCT06484244
- Testing
- 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Spinal Cord Injuries (SCI), Paralysis, Lower Limbs
Epidural Electrical Stimulation to Restore Standing and Walking in Patients With Chronic Paralysis Due to Spinal Cord Injury: A Study on Motor Recovery, Spasticity Reduction, and Quality of Life Improvement Through Neuromodulation and Intensive Rehabilitation
Spinal cord injury (SCI) is a major cause of morbidity and disability worldwide, significantly impacting patients' quality of life and functional independence.
- Trial name
- EPISTIM-SCI (NCT06847295)
- Testing
- Epidural Electrical Stimulation (EES) using an implanted paddle lead and pulse generator combined with a 12-month intensive rehabilitation program.
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo General Hospital
Multiple Sclerosis, Walking Impairment
A Safety and Efficacy Study of ADS-5102 in Patients With Multiple Sclerosis and Walking Impairment
This study assessed the long-term safety and tolerability of ADS-5102 in subjects with MS and walking impairment who had completed the double-blind, placebo-controlled study of ADS-5102 in subjects with MS (ADS-AMT-301).
- Trial name
- NCT03567057
- Testing
- ADS-5102, 274 mg
- Where
- 92 sites in United States, Canada
- Volunteers
- 424 people
- Sponsor
- Adamas Pharmaceuticals, Inc.
Multiple Sclerosis, Upper Extremity Problem
Arm Swing During Walking in Early Multiple Sclerosis
Multiple sclerosis (MS) is the most common central nervous system inflammatory demyelinating disease which causes motor and sensory deficits, cerebellar symptoms, and balance problems.
- Conditions
- Multiple Sclerosis, Upper Extremity Problem, Gait Disorders, Neurologic
- Trial name
- NCT05821257
- Testing
- Evaluation of the arm swing during gait, Functional Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Stroke
Gait Training in Post-Stroke Hemiparesis Hemiparesis
The focus of this study is to optimize the delivery of a combined strength and aerobic training regimen to individuals with post stroke hemiparesis and reduce overuse and inefficiencies associated with the nonparetic leg during…
- Trial name
- NCT04877249
- Testing
- Split-belt treadmill training
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns, Muscle Weakness
Reallocating Rehabilitation Time to Wii Fit or Pilates After Lower-Limb Burn Injury
This randomized controlled trial will evaluate whether reallocating part of a fixed-duration supervised rehabilitation session to Wii Fit or Pilates will improve functional outcomes in adults with healed lower-extremity burns.
- Conditions
- Burns, Muscle Weakness, Exercises, Functional Performance
- Trial name
- NCT06081504
- Testing
- Wii fit exercises program, Pilates exercises program, Standard physical therapy program
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Stroke
Augmentation of Locomotor Adaptation Post-Stroke
This project will evaluate two different methods of normalizing the center of mass acceleration (COMa) in individuals post-stroke, specifically focusing on rates and pattern of recovery to analyze walking-specific adaptations as…
- Trial name
- NCT02892084
- Testing
- tDCS
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Multiple Sclerosis
Effects of Motor Imagery and Action Observation in People With Multiple Sclerosis
It was planned to examine the effects of motor imagery and action observation applied in addition to standard rehabilitation in people with multiple sclerosis on walking, fatigue, and trunk control.
- Trial name
- NCT05377476
- Testing
- Motor Imagery training, Action Observation training, standard rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Hacettepe University
Cerebral Palsy
Effects of TOT on Walking in Children With CP
The purpose of the study was to determine the effects of task oriented training (TOT) on walking and balance in children with spastic Cerebral Palsy (CP).
- Trial name
- NCT04561349
- Testing
- Task oriented training, Conventional rehabilitation treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Stroke
Stroke Training to Advance Balance During Locomotor Experiences (STABLE) Trial
The goal of this clinical trial is to learn if a treadmill gait training performed with a new robotic device will improve walking balance and everyday participation in walking activities for adults who have had a stroke.
- Trial name
- STABLE (NCT07802470)
- Testing
- High intensity gait training in Movement Amplification Environment, High intensity gait training in natural environment
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Northwestern University
Traumatic Brain Injury, TBI
Walking After Traumatic Brain Injury in Older Adults
The purpose of this research is to learn if different behavioral interventions can change walking behaviors over 12-weeks, in older adults who have previously suffered a non-penetrating mild or moderate TBI.
- Conditions
- Traumatic Brain Injury, TBI, Mild Traumatic Brain Injury, Moderate Traumatic Brain Injury
- Trial name
- NCT06222502
- Testing
- Planning, Reminders, and Micro-Incentives, Health Education
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Timothy Morris
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