Clinical trials: Amino Acid Absorption
Protein Malabsorption
Protein Digestion and Amino Acid Absorption in the Aging Gastrointestinal Tract
Rationale: Worldwide, the aging population is increasing. Aging is associated with loss of independence and increased risk of co-morbidity.
- Trial name
- AgingGut (NCT06553794)
- Testing
- Gastroscopy with duodenal mucosal tissue biopsies
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Renin-Angiotensin Aldosterone System (RAS)
Human Intestinal Amino Acid Absorption and the Role of a Local RAS
This study is to find out what role a local intestinal RAS (renin angiotensin system) plays in the context of amino acid absorption in the human intestinal tract and how this RAS and thus the amino acid absorption is influenced…
- Trial name
- NCT04524494
- Testing
- biopsy of intestinal tissue, blood draw, urine collection
- Where
- 2 sites in Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital Basel
Muscle Protein Synthesis, Amino Acid
Influence of Carbohydrate on Amino Acid Absorption From Dietary Protein (ICADP)
10 young males will be recruited to participate in a randomized double blinded crossover study to investigate the influence of concomitant intake of two different types of carbohydrate with protein hydrolysate on the absorption…
- Trial name
- ICADP (NCT03303729)
- Testing
- Meat Hydrolysate, Cluster Dextrin
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Protein Absorption and Amino Acid Availability, Metabolomics
Measurement of Acute Metabolite Changes Following Consumption of Microalgae Drinks
Protein consumption is essential for various physiological processes, with microalgae and plant proteins gaining increasing attention due to their health benefits.
- Trial name
- NCT07791420
- Testing
- Bead-milled microalgae, Non-bead-milled microalgae, Whey protein isolate
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Chronic Kidney Failure
Chronic Kidney Disease in Relation to Alterations in Protein and Amino Acid Metabolism and Function
Weight loss commonly occurs in patients with chronic kidney disease (CKD), negatively influencing their quality of life, treatment response and survival.
- Trial name
- NCT01890811
- Testing
- Boost High Protein
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas A&M University
Protein Absorption and Amino Acid Availability
MA of Tryptophan in Cornmeal in Healthy Adults>60y
The world's population will reach 12 billion by this century's end. As the human population increases, the world faces the continuous challenge of optimizing a limited food supply.
- Trial name
- NCT07272668
- Testing
- Tryptophan
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Protein Digestion, Gastrointestinal Microbiome
Effect of Probiotics on Amino Acid Absorption
The goal of this clinical trial is to test effects of consuming probiotics in healthy adults. The main question it aims to answer is: Do consuming probiotics affect a healthy adult's ability to absorb amino acids from plant…
- Trial name
- NCT05752266
- Testing
- AMILI Probiotic pills
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Technology
Fractional Zinc Absorption
Determination of Pre-Absorptive Dissociation of Zinc From a Zinc Amino Acid Complex in Healthy Men
Zinc may be absorbed from diet via zinc transporter mediated pathways, or, when coupled with amino acids, via amino acid transporter pathways.
- Trial name
- NCT03934346
- Testing
- Zinc amino acid complex
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Amino Acid Absorption, Probiotic
Changes in Amino Acid Absorption After Adding a Probiotic to an Acute Protein Feeding
The purpose of this study is to examine the rate and concentration of amino acid absorption after a three-week pattern of milk protein supplementation with and without the addition of a single strain probiotic.
- Trial name
- NCT06701604
- Testing
- Single Strain Probiotic + Milk Protein
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Amino Acid, Exercise
Investigation of TWK10 Administration on the Effects of Amino Acid Absorption
The most common problem among sports people is that no matter how much protein food or products they eat, their sports performance cannot be improved, resulting in failure to achieve breakthroughs in sports performance.
- Conditions
- Amino Acid, Exercise, Probiotic, Body Composition
- Trial name
- NCT05412667
- Testing
- TWK10
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chi-Chang Huang
Absorption of Amino Acids and Peptides
Pharmacokinetic Effect of AstraGin on Arginine Absorption and Nitric Oxide Production in Healthy Subjects
AstraGin increases the absorption of amino acids and peptides in Caco-2 cells and in normal and TNBS-induced rats. Given the potential beneficial applications of AstraGin for health, the effects on L-arginine uptake and nitric…
- Trial name
- NCT05024123
- Testing
- AstraGin
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Protein Malabsorption
The Incorporation of Dietary Protein-Derived Amino Acids in Duodenal Epithelium
Rationale: Aging is accompanied by a blunted muscle protein synthetic response to protein ingestion.This anabolic resistance may be related to decreased postprandial amino acid release in the circulation, due to greater amino…
- Trial name
- GutFeeding (NCT06091852)
- Testing
- Intrinsically labelled milk protein
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Amino Acid Absorption
Changes in Amino Acid Absorption After Adding a Probiotic to an Acute Protein Feeding
The purpose of this study is to examine the pharmacokinetic pattern of amino acid absorption after a two-week pattern of milk protein supplementation with and without the addition of Bacillus coagulans GBI-30, 6086.
- Trial name
- NCT04427020
- Testing
- Milk protein + GBI-30, Milk protein
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Dietary Zinc Absorption
Effects of Dietary Folate and Phytate Zinc Absorption: Zinc Amino Acid Complexes vs. Zinc-chloride
The purpose of this study is to determine the effects of consuming a small breakfast of juice and toast with added phytate or with taking a folic acid supplement on the absorption of a small amount of zinc that is either bound to…
- Trial name
- NCT05273710
- Testing
- Regular toast and juice, High phytate toast and juice, Regular toast and juice, with folic acid
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Healthy Aging
The Bioavailability of Multiple Novel, Sustainable, Non-animal Derived Protein Sources
The progressive age-related loss of muscle mass is termed sarcopenia. Consequences of sarcopenia are, but not limited to, decreased muscle strength, frailty, and an increased risk for the development of chronic metabolic…
- Trial name
- NOVA (NCT04297137)
- Testing
- Protein ingestion
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Pea Proteins, Muscle Damage
Effects of Pea Proteins on Muscle Damage and Recovery
This study is a double-blind, randomized, placebo-controlled, crossover clinical trial of N=40 recreationally active men to be recruited a single investigational center in Ohio (i.e., The Center for Applied Health Sciences).
- Conditions
- Pea Proteins, Muscle Damage, Amino Acid Change
- Trial name
- NCT05657314
- Testing
- Active Comparator
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Healthy
cGMP: Metabolism and Appetite Modulation
Phenylketonuria is an inborn error of phenylalanine metabolism. Although the phenylalanine-restricted diet is recognized as the mainstay of therapy, little is known about the impact of protein substitutes on the metabolism of…
- Trial name
- NCT06794515
- Testing
- cGMP-AAs alone (20 g of protein equivalent), cGMP-AAs (20 g of protein equivalent) + 50 g of low-protein bread + 160 g of unpeeled apple, cGMP-AAs (20 g of protein equivalent) + 50 g of low-protein bread + 10 g of olive oil
- Where
- Portugal
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Healthy Participants, Hypertension
Human Intestinal Amino Acid Absorption and the Role of a Local (Renin)-Angiotensin System (RAS)
Aim of this trial is to investigate the expression and localisation of different amino acid transporters and their regulatory proteins derived from the regulatory proteins of the local renin angiotensin system (RAS) in the…
- Trial name
- NCT01252368
- Testing
- hypertension
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Amino Acid Absorption, Amino Acid Plasma Profile
Spoonable Bioavailability
The key research objective is to characterise the amino acid (AA) bioavailability for 4 hours following consumption of a single serving of a high protein spoonable yoghurt, compared to a micellar casein drink or a flavoured…
- Conditions
- Amino Acid Absorption, Amino Acid Plasma Profile, Amino Acids, Essential
- Trial name
- BOLT_Part A (NCT06733142)
- Testing
- Test Product: Yoghurt, Micellar casein drink
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Glyn Howatson
Chronic Heart Failure, Pulmonary Disorder, Chronic Obstructive
Method To Measure Protein Digestion & Absorption
The aim of the present study is to validate a new method in healthy volunteers and those diagnosed with COPD and CHF that is able to measure protein digestion and absorption simultaneously.
- Trial name
- NCT02065141
- Testing
- sip feeding with stable isotope infusion
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Texas A&M University