Clinical trials: Amino Acids, Essential
Military Operational Stress Reaction, Malnutrition (Calorie)
Physiological Response to Protein and Energy-enhanced Food Products During Winter Military Training
Soldiers commonly lose muscle mass during training and combat operations that produce large energy deficits (i.e., calories burned > calories consumed).
- Conditions
- Military Operational Stress Reaction, Malnutrition (Calorie), Weight Loss, Muscle Wasting
- Trial name
- NCT05210205
- Testing
- EAA, Energy Dense, Control
- Where
- Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Older Adults Without Any Specific Clinical Condition
Essential Amino Acid Supplementation Enhances Post-prandial Amino Acid Availability Following a Standard-protein Breakfast in Older Adults
Healthy older adults and those who have acute and chronic conditions suffer from reduced protein intake and are at risk of developing both chronic and acute sarcopenia.
- Trial name
- NCT07754760
- Testing
- Essential amino acid supplement
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Muscle Protein Synthesis, Whole-body Protein Balance
Essential Amino Acids and Protein Kinetics During Caloric Deprivation
The amount of essential amino acids (EAA) necessary to maximally stimulate muscle protein synthesis and optimize whole-body net protein balance during caloric deprivation has not been determined.
- Trial name
- NCT03372928
- Testing
- Standard EAA, High EAA
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Healthy Males
The Importance of Non-essential Amino Acids for Maintaining Skeletal Muscle Protein Synthesis Rates in Healthy Young Men
Background: Protein intake is important for maintaining skeletal muscle mass. These proteins consist of a collection of small building blocks which are called amino acids.
- Trial name
- NEAA (NCT06687343)
- Testing
- EAA Supplement, NEAA Supplement, Maltodextrin Supplement
- Where
- Netherlands
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Old Age
Modulation of Muscle Protein Metabolism by Essential Amino Acids
The investigators plan to explore the ability of amino acids, the building blocks of proteins in our bodies and in the food we eat, to stimulate muscles to grow and stay strong.
- Trial name
- Aj1B (NCT01890369)
- Testing
- 15g Mixed Essential Amino Acids, 3g Leucine, 15g Mixed Essential Amino Acid REFEED
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Muscle Loss, Muscle Anabolism
Essential Amino Acids Supplementation and Muscle Protein Synthesis
The modern warfighter faces numerous physiological challenges including sleep deprivation, sustained intense physical activity, and caloric restriction, the combined effects of which may result in the loss of lean body mass and…
- Trial name
- NCT01366924
- Testing
- Essential Amino Acids, Endurance exercise
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Healthy Subjects
Pea vs Whey Protein Supplementation With Resistance Training on Young Adults' Strength, Body Composition, and Metabolic Parameters
The goal of this clinical trial is to compare the impact of pea protein or whey protein supplementation during a progressive resistance exercise (PRE) regimen on body composition and strength in young adults who are not…
- Trial name
- NCT07420933
- Testing
- Protein Isolate, Progressive Resistance Exercise Training (PRE)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Sarcopenia
Effect of an EAA/Whey Composition on Protein Metabolism
Sarcopenia, a progressive loss of muscle mass, strength and function, is an inevitable natural process of aging. While it may be impossible to completely reverse the progress of sarcopenia, it is well established that intake of…
- Trial name
- NCT03502941
- Testing
- 6.3 g of EAAs mixture and whey protein isolate, 12.6 g of EAAs mixture and whey protein isolate, 12.6 g of whey protein isolate
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Anterior Cruciate Ligament Reconstruction, Muscular Atrophy
Nutritional Intervention to Enhance Recovery After Arthroscopic Knee Surgery in Adults
Loss of skeletal muscle mass (atrophy) and strength in the lower limb are consequences of elective knee surgery as result of prolonged disuse from limb immobilization and impaired mobility, as well as pathophysiological trauma.
- Trial name
- NCT06233825
- Testing
- Omega-3 Fatty Acids and Essential Amino Acids, Safflower Oil and Non-Essential Amino Acids
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Chris McGlory, PhD
Sarcopenia
Effect of Exercise and Protein Supplementation on Muscle Function in Patients With Hemodialysis
Sarcopenia can be easily observed in patients with hemodialysis. However, there were few studies on the precise concept and diagnostic criteria for sarcopenia in patients with hemodialysis.
- Trial name
- NCT04927208
- Testing
- exercise and nutritional support
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Chungnam National University Hospital
Skeletal Muscle, Extracellular Matrix
Effects of Essential and Non-Essential Amino Acids on Post-Exercise Muscle Collagen Synthesis in Young Men
The purpose of this study is to assess which amino acids are affecting acute muscle collagen synthesis in response to supplementation and exercise.
- Conditions
- Skeletal Muscle, Extracellular Matrix, Amino Acids Metabolism, Exercise
- Trial name
- PECS (NCT04596553)
- Testing
- Essential Amino Acid, Collagen Peptide
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Energy Deficit
Effects of Essential Amino Acid-enriched Whey and Carbohydrate Co-ingestion on Protein Kinetics
Previous work conducted by the Investigators demonstrates that an essential amino acid(EAA)-enriched whey protein combination format is an efficient EAA/protein format to support enhanced whole-body protein balance and sustain…
- Trial name
- NCT04621175
- Testing
- EAA+W & Carbohydrate, EAA+W & EAA
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Malnutrition Elderly, Protein Malnutrition
The Effect of a Plant-based, Protein-dense Sauce on Essential Amino Acid Concentrations and Gut Fullness in Older Adults
The goal of this clinical trial is to determine whether meals fortified with plant-based high protein sauce (ProSauce) provide better metabolic availability of essential amino acids compared to meals with standard lower-protein…
- Trial name
- ProSauce (NCT06965699)
- Testing
- ProSauce, low-protein sauce
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Amino Acids, Essential, Metabolism
Impact of Amino Acids to Enhance Anabolism After Home-based Exercise
An adequate quantity of lean body mass is vital for optimal health and performance, and is accrued when net protein balance (NPB) is positive.
- Conditions
- Amino Acids, Essential, Metabolism, Exercise
- Trial name
- B2B (NCT04850820)
- Testing
- Novel essential amino acid supplementation, Branched-chain amino acid supplementation (BCAA), Isocaloric carbohydrate supplementation
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Nutrition Deficiency Due to A Particular Kind of Food
Quality of Protein From the Common Bean
Dietary Protein quality is based on digestion of proteins to amino acids and the bioavailability of the amino acids to maintain good health and body function.
- Trial name
- NCT04118517
- Testing
- Using intrinsically labelled bean protein to assess bioavailability of amino acids in healthy adults
- Where
- Jamaica
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Bioavailability of Amino Acids
Amino Acids in the Blood After Eating Yoghurt and Milk Proteins
Participants will visit the study site twice in a fasting state. Participants asked to consume one of the two study products in a random order. Participants will consume one serving of the study product (T = 0 minutes).
- Trial name
- NutraFerm2 (NCT07243730)
- Testing
- Full fat yogurt (fermented), Generic full fat pasteurized milk (non-fermented)
- Where
- Netherlands
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Amino Acid Absorption, Amino Acid Plasma Profile
Spoonable Bioavailability
The key research objective is to characterise the amino acid (AA) bioavailability for 4 hours following consumption of a single serving of a high protein spoonable yoghurt, compared to a micellar casein drink or a flavoured…
- Conditions
- Amino Acid Absorption, Amino Acid Plasma Profile, Amino Acids, Essential
- Trial name
- BOLT_Part A (NCT06733142)
- Testing
- Test Product: Yoghurt, Micellar casein drink
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Glyn Howatson
Increased Metabolic Requirement, Healthy
Effect of Non-essential Amino Acids on Protein Requirements for Endurance Athletes
Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).
- Trial name
- EA3 (NCT02874638)
- Testing
- BASE egg protein, BCAA-enriched egg protein, small amount of essential amino acids
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Protein Deposition
Protein Source on Plasma Amino Acid Concentrations In Older Adults
This study will determine the effect of the same ounce-equivalents of fresh pork versus nuts, beans, and eggs on postprandial plasma essential amino acid availability in older adults.
- Trial name
- S55 (NCT04243395)
- Testing
- Pork, Egg, Black beans
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Purdue University
Protein Deposition
Protein Source on Plasma Amino Acid Concentrations
This study will determine the effect of the same ounce-equivalents of fresh pork versus nuts, beans, and eggs on postprandial plasma essential amino acid availability in adults. Each participant will receive all four treatments.
- Trial name
- NCT03649568
- Testing
- Pork, Egg, Black beans
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Purdue University