Clinical trials: Amputation of Upper Limb
Prosthesis User, Prosthesis
Optimize Pattern Recognition Control of Powered Upper Limb Prosthesis
This study is focused on optimizing methods for controlling upper-limb myoelectric prosthetic arms. If you are enrolled in this study you would be expected to visit one of the research sites for approximately 5 in-lab visits…
- Conditions
- Prosthesis User, Prosthesis, Prosthetic, Upper Limb Amputation
- Trial name
- NCT07850544
- Testing
- Condition A: Electrode Configuration, Condition B: Electrode Configuration, Condition C: Electrode Configuration
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Liberating Technologies, Inc.
Amputation, Lower Limb
Virtual Reality in the Rehabilitation in Patients With Lower Limb Amputation.
The goal of this clinical trial is to test the impact of virtual reality on rehabilitation for the patients after a major amputation.
- Conditions
- Amputation, Lower Limb, Rehabilitation, Activities of Daily Living
- Trial name
- NCT05773560
- Testing
- virtual reality rehabilitation
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Erlangen
Amputation, Amputation, Traumatic
Evaluation of Dexterous Terminal Device
Liberating Technologies, Inc. (LTI) has developed Pointdexter, a dexterous prosthetic fingertip that is integrated into a commercial prosthetic hand and allows for an additional fine grasp.
- Conditions
- Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Limb; Absence, Congenital, Upper
- Trial name
- NCT05840601
- Testing
- Pointdexter, Comparator
- Sponsor
- Liberating Technologies, Inc.
Amputation of Upper Limb, Agenesis of Upper Limb
Using Sensorimotor Reorganization Following Upper Limb Amputation to Improve Prosthetic Control
Amputation of an upper limb results in a disruption of the sensorimotor loop and a reorganization of the nervous system, leading to the emergence of a phantom limb and the adaptation of compensatory motor strategies.
- Trial name
- REINVENT (NCT07666204)
- Testing
- Caracterisation, Mapping, Phantom sensations
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Upper Limb Amputation Below Elbow
Evaluation of a Multi-electrode Prosthesis Control System for Real-world Tasks Performance in Individuals With Upper Limb Transradial Amputation
This study tests how well the Phantom X prosthesis control system works. The system helps control a prosthetic hand using muscle signals from the arm. You'll wear a non-invasive version for one day in the clinic.
- Trial name
- EMPOWER (NCT07071584)
- Testing
- Cutaneous Prosthesis Control System
- Where
- 2 sites in United States
- Sponsor
- Phantom Neuro Inc.
Prostheses, Upper Limb Amputation Below Elbow
Wireless Prosthetic Control Effectiveness Study
The goal of this proposed project is to evaluate the effectiveness of our novel wireless electrode system, which the investigators refer to as the Asterisk system, on transradial prosthesis users.
- Trial name
- NCT06821412
- Testing
- ASTERISK System, Wired Configuration
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Liberating Technologies, Inc.
Lower Limb Amputation Above Knee (Injury)
C-Leg 3 and C-Leg 4 Study in Transfemoral Amputees
The aim of this post-market study is to confirm that the microprocessor controlled prosthetic knee components (C-Leg 3 and C-Leg 4) in comparison to mechanical knee joints can bring additional benefit to the users primarily on…
- Trial name
- NCT02765035
- Testing
- C-Leg 4, C-Leg 3
- Where
- 2 sites in Austria, Belgium
- Volunteers
- 18 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Peripheral Arterial Disease, Peripheral Vascular Disease
The Effect of Ischemic Conditioning on Strength and Ambulation in Subjects with PAD
Lower limb amputation is common in the United States, with approximately 150,000 amputations annually. Most individuals walking with a prosthesis demonstrate asymmetrical loading-i.e., they favor the amputated side by placing…
- Conditions
- Peripheral Arterial Disease, Peripheral Vascular Disease, Amputation, Lower Limb Amputation Knee
- Trial name
- NCT04937179
- Testing
- Ischemic Conditioning High - Active Comparator
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Illinois at Chicago
Amputation
Enhanced Tactile (Touch) Spatial Acuity in Upper Limb Amputees
This study will examine whether tactile (touch) abilities at the lip are more acute in people with upper limb amputation compared with healthy normal volunteers.
- Trial name
- NCT00028210
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Traumatic Amputation of Arm
Interface Kinematics of Transhumeral Prosthetic Sockets Using XROMM
The purpose of this pilot study was to conduct a head-to-head comparison of two designs for transhumeral level upper limb prosthetic sockets: a traditional socket design and a socket design hypothesized to provide greater…
- Trial name
- NCT01546675
- Testing
- Skeletal Stabilization
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- US Department of Veterans Affairs
Prosthesis User, Congenital Amputation of Upper Limb
Pattern Recognition Prosthetic Control
This study investigates whether simultaneous electromyographic (EMG)-based pattern recognition control of an upper limb prostheses increases wear time among users.
- Conditions
- Prosthesis User, Congenital Amputation of Upper Limb, Amputation; Traumatic, Limb
- Trial name
- Simultaneous (NCT04272593)
- Testing
- EMG-Pattern Recognition Controller
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Coapt, LLC
Amputation
Effectiveness of Frontal Plane Adaptability in a Novel Foot Prosthesis
People with lower extremity amputation (LEA) have persistent problems with balance, falls, residual limb pain, functional mobility, cognitive attention during gait, and satisfaction with participation in daily activities, despite…
- Trial name
- NCT06214026
- Testing
- META-Arc foot locked, META-Arc foot unlocked
- Where
- 3 sites in United States
- Volunteers
- 96 people
- Sponsor
- University of Washington
Upper Limb Amputation, Postural Control
The Relationship Between Lost Extremity Percentage and Postural Control, Neck and Low Back Pain, Daily Living Activities, and Reaction Time in Individuals With Unilateral Upper Limb Amputation
This observational study aims to examine the relationship between the percentage of limb loss and functional outcomes in individuals with unilateral upper limb amputation.
- Conditions
- Upper Limb Amputation, Postural Control, Neck Pain, Low Back Pain
- Trial name
- NCT07677969
- Testing
- This is an observational study. No interventional procedures are performed. All assessments are non-invasive measurements.
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Hacettepe University
Amputation, Traumatic, Prosthesis User
Evaluation of a Non-invasive Sensory Feedback System in Hand Prostheses
Implication and evaluation of a non-invasive sensory feedback system in hand prostheses in everyday life.
- Trial name
- NCT03876405
- Testing
- smartskin non-invasive sensory feedback
- Volunteers
- 7 people
- Sponsor
- Lund University Hospital
Below Elbow Amputation
Enhancing Upper Limb Prostheses With Radio Frequency Identification
The purpose of this study is to determine if Radio Frequency Identification (RFID) can lead to greater prosthesis function and control.
- Trial name
- RFIDIBT (NCT01967004)
- Testing
- Morph
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Infinite Biomedical Technologies
Upper Limb Amputation Below Elbow (Injury), Wrist Disarticulation
Evaluation of the Phantom X Implantable EMG Sensor System for Myoelectric Prosthesis Control
The CYBORG Study is a first-in-human clinical investigation evaluating the safety and performance of the Phantom X System, an implantable electromyography (EMG) sensor array designed to provide control of upper-limb prostheses.
- Conditions
- Upper Limb Amputation Below Elbow (Injury), Wrist Disarticulation, Transradial Amputation
- Trial name
- CYBORG (NCT07325708)
- Testing
- Phantom X multielectrode EMG sensor array implant for upper limb prosthesis control
- Where
- 2 sites in Australia
- Volunteers
- 10 people
- Sponsor
- Phantom Neuro Inc.
Transradial Amputation
Evaluation of Upper Extremity Prosthesis
The purpose of this study is to evaluate a design of prosthesis that is inexpensive and able to fit a multitude of individuals. This may offer an off the shelf item for those that cannot afford a customized prosthesis, or wish to…
- Trial name
- NCT00584103
- Testing
- Alpha P Control, Beta P Experimental
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Oklahoma
Amputation, Amputation; Traumatic, Hand
Dexterous Partial Hand Prosthesis Outcomes
Liberating Technologies, Inc. (LTI) has developed a dexterous prosthetic fingertip that will be fit onto an i-Digits™ partial hand prosthesis and allow for an additional fine grasp.
- Conditions
- Amputation, Amputation; Traumatic, Hand, Limb; Absence, Congenital, Upper, Prosthesis User
- Trial name
- NCT05038566
- Testing
- Pointdexter
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Prosthesis, Amputation
Functional Outcomes of Voice Recognition Prosthesis
The purpose of this study is to evaluate the use of a voice activated prosthesis interface controller for functional outcomes as compared to standard prosthesis control.
- Conditions
- Prosthesis, Amputation, Prosthesis User
- Trial name
- NCT04595071
- Testing
- Voice Activated Prosthetic Interface (VAPI) Controller
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Lower Limb Amputation Above Knee, Below Knee Amputation
Determining the Effects of Ischemic Conditioning and Neuromuscular Electrical Stimulation on Overall Function After Lower Limb Amputation
The goal of this clinical trial is to learn if ischemic conditioning and neuromuscular electrical stimulation improves muscle strength and walking behavior in those with limb loss.
- Trial name
- NCT07664995
- Testing
- Blood pressure cuff, Neuromuscular Electrical Stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Illinois at Chicago