Clinical trials: Analgesia, Epidural
Epidural; Analgesia, Local Infiltration
Comparison of Epidural Analgesia With Intra-Articular Infiltration Analgesia
The results of combining infiltrative analgesia applied by orthopedists with epidural analgesia applied by anesthesiologists after knee replacement surgery will be compared.
- Trial name
- NCT06872528
- Testing
- Recording the amount of medication and the number of complications according to observational follow-up
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Acute Post Operative Pain, Laparotomy
PIB for Post-operative Analgesia After Laparotomy : Determining the Optimum Dose
Pain control after surgery is a crucial component of postoperative recovery. Thus, in open abdominal surgery, the use of TEA (Thoracic epidural analgesia) has become a gold standard.
- Conditions
- Acute Post Operative Pain, Laparotomy, Epidural Analgesia
- Trial name
- PIBDOSE (NCT05534945)
- Testing
- Programmed intermittent epidural bolus 5 ml, Programmed intermittent epidural bolus 6 ml, Programmed intermittent epidural bolus 7 ml
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Epidural Analgesia for Labour and Delivery
M-mode Ultrasonography for Epidural Catheter Identification and Confirmation of Correct Catheter Position
In France, 80% of women choose epidural analgesia for delivery and birth. The localization of the epidural space is classically achieved by loss of resistance to saline.
- Trial name
- ETEMERC (NCT05897814)
- Testing
- Location of the epidural analgesia catheter
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Labor Epidural Analgesia, Perfusion Index
Perfusion Index Variability During Epidural Labor Analgesia
This prospective, single-centre observational study evaluates changes in the peripheral Perfusion Index (PI) - a non-invasive parameter derived from the pulse-oximetry photoplethysmographic waveform - in women receiving epidural…
- Conditions
- Labor Epidural Analgesia, Perfusion Index, Pain
- Trial name
- NCT07831967
- Testing
- Epidural (or opioid-only combined spinal-epidural) labor analgesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Gdansk
Failed Epidural Analgesia, Post-partum Recovery
Failing Epidural Analgesia During Labor
This prospective multicenter observational study is being conducted at the Gregorio Marañón University General Hospital and the La Paz University Hospital in Madrid, Spain.
- Trial name
- FEA25 (NCT07473609)
- Testing
- No Intervention: Observational Cohort
- Where
- 2 sites in Spain
- Volunteers
- 500 people
- Sponsor
- Nicolas Brogly
Bilateral Rectus Sheath Block, Thoracic Epidural Analgesia
Bilateral RSB vs TEA Epidural Analgesia for Postoperative Pain Control After Open Gastrectomy: A Randomized Controlled Trial
Patients indicated for elective open gastrectomy were screened, enrolled, and randomised between October 2021 and September 2023.
- Trial name
- NCT07634731
- Testing
- Bilateral Rectus Sheath Block and Thoracic Epidural Analgesia for Postoperative Pain Control After Open Gastrectomy.
- Where
- Latvia
- Volunteers
- 60 people
- Sponsor
- Igors Ivanovs
Labor Pain, Epidural Analgesia
Epidural vs. Dural Puncture Epidural in Labor Analgesia
Childbirth is an intense physical and psychological experience. Epidural analgesia (EP) remains the gold standard in labor pain management.
- Trial name
- NCT06849726
- Testing
- Standard Epidural Analgesia, Dural Puncture Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Medipol University
Labor Pain, Epidural Analgesia for Labour and Delivery
Early Labor Pre-Marking for Epidural Analgesia: Ultrasound vs Manual Palpation
The goal of this clinical trial is to learn if finding and marking the best spot on the back early in labor helps doctors perform epidural pain relief more successfully in pregnant women.
- Conditions
- Labor Pain, Epidural Analgesia for Labour and Delivery, Neuraxial Ultrasound
- Trial name
- NCT07669441
- Testing
- Preprocedural Spinal Ultrasound, Conventional Landmark Palpation
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Epidural Analgesia, Epidural Analgesia for Labour and Delivery
EpiFaith Resident Learning Curve Trial
This study aims to evaluate the impact of the EpiFaith® syringe on the learning curve of anesthesia residents for the labor epidural technique.
- Conditions
- Epidural Analgesia, Epidural Analgesia for Labour and Delivery, Learning Curve
- Trial name
- NCT07395622
- Testing
- EpiFaith epidural syringe, Control (glass) syringe
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Labour Analgesia, Epidural Anaesthesia
Higher vs Lower Lumber Epidural Catheter Insertion During Labour: A Randomised Trial to Compare Efficacy.
This study will randomise pregnant women to labour epidural at a higher versus a lower lumbar level. Outcomes relating to success or failure of the epidural catheter at this level will be assessed.
- Trial name
- NCT06850636
- Testing
- Epidural Analgesia
- Where
- Ireland
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- The Rotunda Hospital
Labor, Obstetric, Epidural Analgesia, Obstetric
Integrated Intrapartum Supportive Care and Pushing Strategies in Women Receiving Low-Dose Epidural Analgesia
This prospective, three-arm, non-randomized quasi-experimental study aims to evaluate integrated intrapartum supportive care combined with different pushing strategies among women at 37-42 weeks of gestation who receive low-dose…
- Conditions
- Labor, Obstetric, Epidural Analgesia, Obstetric, Labor Duration
- Trial name
- NCT07663500
- Testing
- Integrated Care with Immediate Pushing, Integrated Care with Spontaneous Pushing Group, Standard Routine Care
- Where
- Taiwan
- Volunteers
- 159 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Pregnant Women, Labor Pain
Neuraxial Labor Analgesia and Offspring Neurodevelopment
How perinatal factors affect the long-term development of children has always been an issue of much concern. This study is designed to explore the potential impact of maternal neuraxial labor analgesia exposure on offspring…
- Conditions
- Pregnant Women, Labor Pain, Analgesia, Epidural, Infants
- Trial name
- NCT04964206
- Testing
- Neuraxial labor analgesia, No neuraxial labor analgesia
- Where
- 2 sites in China
- Volunteers
- 4,645 people
- Sponsor
- Dong-Xin Wang
Thoracic Epidural Analgesia, Gastric Cancer
General Anesthesia and General Anesthesia Combined With Thoracic Epidural Anesthesia
This randomized controlled trial investigated whether adding thoracic epidural analgesia to general anesthesia affects intraoperative neuromuscular blockade and opioid requirements in patients undergoing gastric cancer surgery.
- Trial name
- NCT05907811
- Testing
- Neuromuscular blocker usage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Total Knee Anthroplasty, Epidural Analgesia
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Postoperative Analgesia After Total Knee Arthroplasty
The goal of this clinical trial is to compare two different epidural analgesia delivery methods for pain control after total knee arthroplasty in adults undergoing elective surgery.
- Trial name
- NCT07605208
- Testing
- Programmed intermittent epidural bolus 6 ml, continuous epidural infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Epidural Analgesia, Labor Pain
Dexmedetomidine-esketamine-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia
Sufentanil-ropivacaine combination is commonly used for epidural labor anesthesia, but is associated with some adverse events. Dexmedetomidine and esketamine, each has been effectively used for neuraxial anesthesia in combination…
- Conditions
- Epidural Analgesia, Labor Pain, Sufentanil, Dexmedetomidine
- Trial name
- NCT07145775
- Testing
- sufentanil-ropivacaine combination, dexmedetomidine-esketamine-ropivacaine combination 1, dexmedetomidine-esketamine-ropivacaine combination 2
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
Open Abdominal Surgery, Epidural Analgesia
"Diagnostic Accuracy of Ultrasound Compared to Epidurography for Epidural Catheter Localization"
The goal of this clinical trial is to evaluate the effectiveness of ultrasound for locating epidural catheters compared to the gold standard, epidurography.
- Trial name
- NCT06556836
- Testing
- Doppler color and M-Mode ultrasound, Epidurography
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Pregnancy Related, Analgesia, Epidural
Dural Puncture Epidural vs Standard Epidural Analgesia in Labor
This randomized prospective study compares Dural Puncture Epidural (DPE) and Standard Epidural Analgesia in term laboring women.
- Conditions
- Pregnancy Related, Analgesia, Epidural, Labor Pain
- Trial name
- DPE-LABOR (NCT07278895)
- Testing
- Dural Puncture Epidural (DPE), Standard Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
General Anesthesia, Chronic Pain, Postoperative
Risk Factors for Chronic Postoperative Pain After Elective Nephrectomy
Chronic postoperative pain (CPP) is typically defined as pain persisting for 3 months or more after surgery[1]. CPP is a common and increasingly prevalent morbidity, leading to long-term psychological issues, reduced quality of…
- Conditions
- General Anesthesia, Chronic Pain, Postoperative, Acute Pain, Postoperative, Surgery
- Trial name
- NCT06673979
- Testing
- Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people
- Sponsor
- Istanbul University - Cerrahpasa
Epidural Analgesia for Labour and Delivery
Cross-legged Versus Traditional Sitting Position for the Success of Epidural Analgesia During Labor
The success of an epidural analgesia catheter placement depends on the parturient position. A poor posture can increase the number of punctures, patient discomfort, and risk of complications.
- Trial name
- IP3 (NCT04754282)
- Testing
- Position of labouring women for epidural analgesia catheter placement : Traditional Sitting Position (TSP), Position of labouring women for epidural analgesia catheter placement : Cross-legged Sitting Position (CSP)
- Where
- France
- Volunteers
- 457 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Epidural Analgesia, Obstetric, Maternal Satisfaction
Impact of Patient Choice for Epidural Potency on Maternal Satisfaction
This clinical trial will compare two different approaches to epidural analgesia during labor to see which approach leads to higher patient satisfaction after delivery.
- Trial name
- NCT07414407
- Testing
- Patient-selected epidural management, Standard epidural management
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stanford University