Clinical trials: Analgesia, Postoperative
Therapy, Pain Management
Intrathecal Ketamine, Dexmedetomidine and Both With Bupivacaine for Postoperative Abdominal Cancer Surgery Pain
Currently, opioids are widely used for pain relief, but they often provide sub-optimal analgesia with occasional serious side effects.
- Trial name
- NCT02455609
- Testing
- intrathecal drug administration, Dexmedetomidine, ketamine
- Volunteers
- 90 people
- Sponsor
- Assiut University
Pain, Shoulder, Post Operative Pain
The Role of Neurofeedback Training and Pain Management in Post-operative Shoulder Rehabilitation
The primary aim is to compare the efficacy of neurofeedback training (NFT) and pain management protocol (PMP) in pain reduction, restoration of shoulder function, and improved cognitive performance as the post-operative…
- Trial name
- NCT05948007
- Testing
- Neurofeedback training, Pain management protocol
- Sponsor
- Chang Gung Memorial Hospital
Postoperative Pain, Acute, Emergence Delirium
Comparing Ketamine and Fentanyl in Pediatric Tonsillectomy: Pain Control and Emergence Delirium Outcomes (KVFPT)
This study is designed to compare the effectiveness of two medications, ketamine and fentanyl, in managing pain and preventing delirium in children aged 3 to 8 years who are undergoing tonsillectomy and adenoidectomy surgery.
- Trial name
- KVFPT (NCT06630364)
- Testing
- ketamine, fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Medipol University
Postoperative Pain
Deep Subgluteal Block vs PENG Combined With LFCN Block for Analgesia After Hip Arthroplasty
This randomized, prospective study aims to compare the clinical efficacy of ultrasound-guided Deep Subgluteal Block (DSGB) versus Pericapsular Nerve Group (PENG) block combined with Lateral Femoral Cutaneous Nerve (LFCN) block…
- Trial name
- DSG-PENG (NCT07770932)
- Testing
- 0.25% Bupivacaine for Deep Subgluteal Block, 0.25% and 0.125% Bupivacaine for PENG+LFCN Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Postoperative Pain
Adjuvants With Intrathecal Bupivacaine for Postoperative Analgesia
The aim of this study is to compare the postoperative analgesic effect of intrathecal dexmedetomidine combined with bupivacaine and midazolam combined with bupivacaine in high tibial osteotomy.
- Trial name
- NCT06082232
- Testing
- Dexmedetomidine, Midazolam, Bupivacain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Thoracic Surgery, Pneumonectomy
Personalized Postoperative Pain Management Following Thoracic Surgery in Adults
The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research.
- Conditions
- Thoracic Surgery, Pneumonectomy, Lobectomy, Segmentectomy
- Trial name
- NCT05525923
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- OpalGenix, Inc
Arthroplasty, Replacement, Knee, Anesthesia, Conduction
Adductor Canal Vs Adductor Canal Plus SPANK Block for Postoperative Pain in Knee Arthroplasty Surgery
This study will prospectively investigate the efficacy of Adductor canal block with periarticular infiltration Vs Adductor canal block, Periarticluar infiltration and Sensory posterior articular nerve of the knee block in…
- Conditions
- Arthroplasty, Replacement, Knee, Anesthesia, Conduction, Acute Pain
- Trial name
- NCT04290442
- Testing
- adductor canal block, SPANK, Ropivacaine
- Where
- United States
- Sponsor
- Bruce Ben-David
Postoperative Pain, Gas Bloat Syndrome
The Effect of Kinesio Taping and Breathing Exercises on Pain Management
A randomised clinical trial in a single centre.The aim of this study is to evaluate the effect of kinesio taping and breathing exercises on pain management applied after benign gynecological abdominal operations.
- Conditions
- Postoperative Pain, Gas Bloat Syndrome, Defecation Disorders
- Trial name
- NCT04412122
- Testing
- Kinesio Taping, Breathing Exercise, Kinesio Taping+Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Postoperative Pain, Acute, Shoulder Pain
Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block for Analgesia in Arthroscopic Shoulder Surgery
This study aimed to evaluate the effectiveness of serratus posterior superior intercostal plane (SPSIP) block in managing postoperative pain in patients undergoing arthroscopic shoulder surgery.
- Conditions
- Postoperative Pain, Acute, Shoulder Pain, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- SPSIP (NCT07394673)
- Testing
- Group SPSIP: Serratus Posterior Superior İntercostal Plane Block (SPSIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Postoperative Pain Management, RATS Surgery
Compairing R-ICNB and C-ICNB for Postoperative Pain Management After Minimal-invasive Anatomical Lung Resection
This is a pilot study in which a total of 6 people will participate. This study aims to optimize the postoperative pain management of an anatomically minimally invasive lung resection (RATS) by comparing 2 pain-relieving…
- Trial name
- NCT07099469
- Where
- Belgium
- Volunteers
- 6 people
- Sponsor
- University Hospital, Antwerp
Post-operative Pain, Osteoarthritis
Evaluation of the Use of Spinal Epimorph in Total Knee Arthroplasty
The purpose of this study is to determine the contribution of spinal epimorph to patient's perioperative pain management in Total Knee Arthroplasty (TKA).
- Trial name
- NCT01667445
- Testing
- Epimorph, Spinal analgesia
- Where
- Canada
- Volunteers
- 113 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Pain
Clinical Pharmacist-Led Perioperative Pain Management in Orthopedic Surgery: An Effectiveness Evaluation
This study aims to evaluate the effectiveness of a clinical pharmacist-led perioperative pain management model in orthopedic surgery. It is a randomized controlled trial involving patients undergoing major orthopedic procedures.
- Trial name
- NCT07688486
- Testing
- Clinical Pharmacist-Led Pain Management, Standard Perioperative Care
- Volunteers
- 600 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Pain, Postoperative
Pharmacokinetics of Levobupivacaine After Cesarean Section
Transversus abdominis plane (TAP) block provides effective analgesia and is now a standard of care for analgesia after cesarean section. There is no information on levobupivacaine pharmacokinetics post TAP after pregnancy.
- Trial name
- NCT02852720
- Testing
- Levobupivacaine, Spinal anesthesia, Peripheral vein canulation
- Where
- Chile
- Volunteers
- 12 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Anxiety, Cesarean Section Complications
The Effect of Pre-operative Videotape Before a Planned Cesarean Section on Anxiety Level
The study aim is to examine the relationship between providing information to women prior to elective cesarean delivery and anxiety levels around surgery. the patients will be assigned into two groups - intervention and control.
- Conditions
- Anxiety, Cesarean Section Complications, Pain, Postoperative, Analgesia
- Trial name
- NCT04177966
- Testing
- pre-prepared video describing the cesarean surgery, general information
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Pain Management
Comparing the Effectiveness of Hyalone and Calcium Hydroxide in Reducing Post-operative Pain and Promoting Periapical Healing.
This protocol presents a randomized clinical trial comparing Hyalone (hyaluronic acid) with calcium hydroxide as intracanal medicaments in mandibular first molars with necrotic pulp and symptomatic apical periodontitis.
- Trial name
- HCPH (NCT07821866)
- Testing
- Hyalone, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Pain Management, Arthroplasty Total Hip Replacement
QLESP Block Versus PENG+LFCN Block for Total Hip Arthroplasty
Total hip arthroplasty (THA) is a common surgery to replace damaged hip joints, but many patients experience significant pain after surgery, which can delay recovery and increase the need for strong pain medications (opioids).
- Trial name
- QLESP (NCT07771829)
- Testing
- QLESP Block, PENG+LFCN Block, ropivacaine
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Huazhong University of Science and Technology
Pain Postoperative
Pregabalin and Analgesia After Laparoscopic Cholecystectomy
The purpose of this study is to evaluate how effective is the preoperative administration of pregabalin 600mg, to attenuate postoperative pain and opioids consumption after laparoscopic cholecystectomy.
- Trial name
- NCT01321801
- Testing
- Pregabalin
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Larissa University Hospital
Endometriosis; Peritoneum, Postoperative Pain
LTAP Block in Endometriosis Surgery - a Randomised Controlled Double-blind Trial
The purpose of this study is to compare the efficacy and safety of laparoscopically inserted transversus abdominis plane block (LTAP) in comparison to local wound analgesia in laparoscopic surgery due to suspected or diagnosed…
- Trial name
- NCT04735770
- Testing
- Postoperative pain management: LTAP block or local wound anesthesia with levobupivacaine
- Where
- Finland
- Volunteers
- 46 people
- Sponsor
- Oulu University Hospital
Anesthesia, Analgesia
Subcostal Approach to Anterior Quadratus Block Versus Thoracic Paravertebral Block for Laparoscopic Nephrectomy
In this study, it was aimed to evaluate the effects of subcostal anterior quadratus lumborum block (S-QLB3) and thoracic paravertebral block (TPVB) on postoperative acute pain scores and opioid consumption in the first 24 hours…
- Conditions
- Anesthesia, Analgesia, Acute Pain, Patient Controlled Analgesia
- Trial name
- NCT05191966
- Testing
- Subcostal Anterior Quadratus Lumborum Block, Thoracic Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ondokuz Mayıs University
Surgical Injury, Stress, Physiological
Effect of a Bundle of Non-pharmacological Interventions on the Stress Response to Surgery
Rationale: Surgical trauma and post-surgical pain induce a physiological stress response that can be detrimental to the patient.
- Conditions
- Surgical Injury, Stress, Physiological, Stress, Psychological, Pain, Postoperative
- Trial name
- SPACU-lab (NCT05638152)
- Testing
- implementation of a bundle of non-pharmacological interventions aimed at stress reduction
- Volunteers
- 90 people
- Sponsor
- The Netherlands Cancer Institute
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