Clinical trials: Analgesia, Postoperative
Pain
Bupivacaine Pain Pumps to Decrease Mastectomy Post-Operative Pain
This double-blind, randomized, controlled clinical trial comparing patient-reported pain and pain medication/narcotic use between patients randomized to treatment (bupivacaine) or placebo (saline) delivered via pain pump to the…
- Trial name
- NCT01494259
- Testing
- Bupivacaine, Saline
- Where
- United States
- Sponsor
- Johns Hopkins University
Arteriovenous Malformation
Effect of Dexmedetomidine Combined With Sufentanil for Postoperative Intravenous Analgesia in Neurosurgery
The purpose of this study is to determine effect of combined medication of sufentanil and dexmedetomidine in patient controlled analgesia after neurosurgery.
- Trial name
- NCT02552459
- Testing
- Sufentanil, dexmedetomidine 1, dexmedetomidine 2
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Postoperative Pain
Pain Management for Pectus Excavatum Repair
The objective of this study is to scientifically evaluate two different management strategies for post-operative pain after pectus excavatum repair.
- Trial name
- NCT00413582
- Testing
- Epidural Analgesia, Patient-Controlled IV Analgesia
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Children's Mercy Hospital Kansas City
Gastric Cancer (GC), Stomach Neoplasms
TEAS Timing for Gastrectomy Recovery (TEAS-TIME Trial)
The goal of this clinical trial is to learn if transcutaneous electrical acupoint stimulation (TEAS) works to help people recover faster after laparoscopic surgery for stomach cancer.
- Trial name
- NCT07714980
- Testing
- Transcutaneous Electrical Acupoint Stimulation
- Where
- 13 sites in China
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Acute Postoperative Pain, Lower Limb Surgery
Tapentadol vs Pregabalin for Postoperative Pain in Lower Limb Surgery
This pilot randomised controlled trial compared 72-hour oral premedication with tapentadol (50 mg every 12 hours) versus pregabalin (75 mg every 24 hours) for preventing acute postoperative pain in 46 patients undergoing elective…
- Trial name
- NCT07587645
- Testing
- Tapentadol, Pregabalin
- Where
- Mexico
- Volunteers
- 46 people
- Sponsor
- ISSSTE Hospital Regional "Gral. Ignacio Zaragoza"
Living Donors
Postoperative Analgesia After Laparoscopic Living Donor Nephrectomy
The aim of the study is to investigate if perioperative administration of pregabalin vil reduce postoperative pain and the postoperative need for intravenous opioids compared with todays standard treatment which consist of…
- Trial name
- NCT01059331
- Testing
- Pregabalin, Sugar pill
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Pain, Postoperative, Pain
Use of Local Infiltration Analgesia Following Total Hip Arthroplasty
The primary aim of this study is to evaluate if multiple postoperative administrations with a solution of ropivacaine, ketorolac and epinephrine into the operating field through a catheter would affect morphine consumption.
- Trial name
- NCT01344395
- Testing
- ropivacaine and ketorolac, Ketorolac
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Intertransverse Process Block, Subcostal Transverse Abdominis Plane Block
Intertransverse Process Block Versus Subcostal Transversus Abdominis Plane Block After Laparoscopic Sleeve Gastrectomy
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Subcostal Transversus Abdominis Plane Block (TAPB) in patients undergoing laparoscopic sleeve…
- Conditions
- Intertransverse Process Block, Subcostal Transverse Abdominis Plane Block, Sleeve Gastrectomy, Postoperative Pain
- Trial name
- NCT07591129
- Testing
- Intertransverse Process Block, The Subcostal Transversus Abdominis Plane Block (TAPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Pain Management, Laparoscopic Cholecystectomy Surgery
EOIPB in Laparoscopic Cholecystectomy: Impact on Opioid Consumption Guided by ANI and Analgesia Quality
The aim of the study was to evaluate the response of regional anesthesia to remifentanyl consumption in patients undergoing laparoscopic cholecystectomy surgery.
- Trial name
- NCT06869837
- Testing
- Group EOİPB
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun University
Post Operative Pain
Superior Trunk Block Applied for Upper Arm Surgery
Nerve blocks applied with ultrasonography are currently used for many post-operative pain and operations. Providing adequate area analgesia is the primary goal of clinicians, as early mobilization is suggested after shoulder and…
- Trial name
- NCT05474014
- Testing
- superior trunk block, intravenous patient-controlled analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Macromastia, Post-operative Pain
Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty
The main question this randomized control trial aims to answer is: Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who undergo bilateral reduction…
- Trial name
- NCT05898087
- Testing
- Marcaine 0.25 % Injectable Solution, Saline
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Total Hip Replacement, Ultrasound Guided Supra-inguinal Fascia Iliaca Block
The Efficacy of Pain Control After Total Hip Replacement Between Ultrasound Guided Supra-inguinal Fascia Iliaca Block and Intrathecal Morphine
Total hip replacement is one of major orthopedic surgery which result in severe postoperative pain especially at first 24 hours.
- Conditions
- Total Hip Replacement, Ultrasound Guided Supra-inguinal Fascia Iliaca Block, Intrathecal Morphine, Postoperative Pain
- Trial name
- NCT04104204
- Testing
- Intrathecal morphine, Ultrasound guided supra-inguinal fascia iliaca block
- Where
- Thailand
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Peripheral Arterial Occlusive Disease
Interest of a Bi-truncal Nerve Block (Femoral + Sciatic) Extended, Systematically Associated With General Anesthesia, in the Femoropopliteal Bypass: Study of Post-operative Analgesia and Peripheral Circulation Downstream
The aim of this study is to assess, in patients scheduled for femoropopliteal bypass, the benefit of a double peripheral nerve block (femoral + sciatic) with levobupivacaine and clonidine in a single dose, performed before…
- Trial name
- BLOC-FEMPOP (NCT01785693)
- Testing
- levobupivacaine, clonidine
- Where
- France
- Volunteers
- 47 people
- Sponsor
- University Hospital, Clermont-Ferrand
Postoperative Pulmonary Complications (PPCs), Abdominal Surgeries
Can Ultrasound-Guided Fascial Plane Blocks Reduce Postoperative Pulmonary Complications After Major Abdominal Surgery?
This prospective observational study aims to evaluate whether the use of ultrasound-guided fascial plane blocks is associated with a lower incidence of postoperative pulmonary complications in adult patients undergoing elective…
- Conditions
- Postoperative Pulmonary Complications (PPCs), Abdominal Surgeries, Postoperative Pain Management
- Trial name
- FPB-PPC (NCT07394816)
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Hemorrhoid
Laser Hemorrhoidoplasty Versus Open Hemorrhoidectomy for Postoperative Pain
Hemorrhoidal disease is a common condition that can cause symptoms such as rectal bleeding and protrusion of tissue through the anal canal.
- Trial name
- NCT07846904
- Testing
- Open Milligan-Morgan Hemorrhoidectomy, Laser Hemorrhoidoplasty
- Volunteers
- 68 people
- Sponsor
- Allied Hospital Faisalabad
Pain, Acute, Opioid Use
Comparison of Short-term Sustained-release Opioid in Open Abdominal Urologic Surgeries
The advantage of slow-release opioid allows for less fluctuation in drug (pain killer) levels in the blood and an extended period within the effective range for pain relief.
- Trial name
- NCT05375916
- Testing
- Hydromorphone
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Alberta
Knee Osteoarthritis
Investigation of the Effect of Proximal and Distal Adductor Canal Block in Knee Replacement Surgery
to investigate the effect of adductor canal block applied with two different approaches in the treatment of pain after TKA surgery on pain control and functional mobility.
- Trial name
- NCT06188806
- Testing
- ADDUKTOR CANAL BLOCK, CONTROL GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Umraniye Education and Research Hospital
Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children
Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population
The goal of this randomized clinical trial is to determine if administration of Exparel via local infiltration for medial patellofemoral ligament (MPFL) reconstruction procedures in pediatric orthopaedic sports medicine patients…
- Conditions
- Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Trial name
- NCT06559215
- Testing
- Exparel
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Pain, Postoperative
PIB Versus CI Through a Popliteal Sciatic Nerve Catheter for Analgesia Following Major Ankle Surgery
This is a clinical study to investigate and compare a new programmed intermittent bolus (PIB) delivery method for continuous popliteal sciatic nerve block for pain relief in patients undergoing major ankle surgery compared with…
- Trial name
- NCT02707874
- Testing
- CI 0.2% ropivacaine, PIB 0.2% ropivacaine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Postoperative Pain, Opioid Use
STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery Trial
Overprescribing opioids is considered a major contributor to the opioid crisis. Hill et al. demonstrated that within a general surgery practice, over 70% of the prescribed opioid pills were never taken.
- Conditions
- Postoperative Pain, Opioid Use, Prolapse; Female, Incontinence
- Trial name
- STOP-PAIN (NCT04491617)
- Testing
- Standard opioid prescribing, Restrictive opioid prescribing
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- The Cleveland Clinic
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