Clinical trials: Analgesia, Postoperative
Caesarean Section, Postoperative Analgesia
Analgesic Effects of Intrathecal Morphine and Transversalis Plane Block After Cesarean Delivery
A comparison of postoperative pain levels, patient satisfaction, and side effects is planned between patients who received morphine during spinal anesthesia for cesarean section and patients who did not receive morphine but…
- Trial name
- NCT07490795
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 117 people
- Sponsor
- Vezirköprü State Hospital
Pain, Post Operative Nausea and Vomiting
Satisfactory Analgesia Minimal Emesis in Day Surgeries
Currently nearly 70% or more surgeries are being done as ambulatory (day care) procedures as they offer significant benefit to the patients as well as to the hospitals.
- Trial name
- SAME-Day (NCT02223377)
- Testing
- Morphine, Hydromorphone
- Where
- 2 sites in Canada
- Volunteers
- 402 people
- Sponsor
- McMaster University
Acute Pain
Paravertebral Catheters for VATS Procedures
Level I randomized prospective outcomes study comparing two groups of patients. One group will receive Dilaudid patient controlled analgesia (PCA) post-operatively.
- Trial name
- NCT02361775
- Testing
- Paravertebral catheter, opioid iv pca, Ropivacaine
- Volunteers
- 50 people
- Sponsor
- University of Minnesota
Pecto-Intercostal Fascial Block, Transversus Thoracis Muscle Plane Block
Pecto-Intercostal Fascial Block Versus Transversus Thoracic Muscle Plane Block in Cardiac Surgery
The aim of this study is to compare the effect of Ultrasound-Guided Pecto-Intercostal Fascial Block versus Transversus Thoracis Muscle Plane Block on Postoperative Pain Analgesia in Cardiac Surgery
- Conditions
- Pecto-Intercostal Fascial Block, Transversus Thoracis Muscle Plane Block, Cardiac Surgery, Postoperative Analgesia
- Trial name
- NCT05115357
- Testing
- Pecto-Intercostal Fascial Block, Transversus Thoracis Muscle Plane Block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Supracondylar Humerus Fracture
Post-operative Pain Management in Children With Supracondylar Humerus Fractures
There are two common and concurrently used strategies for pain management following surgical treatment of supracondylar humerus (elbow) fractures in children: opioids vs over the counter pain medications.
- Trial name
- NCT05640674
- Testing
- Ibuprofen, Hydrocodone/acetaminophen, Acetaminophen
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Baylor College of Medicine
Quadratus Lumborum Block, Abdominoplasty
Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery
Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery.
- Conditions
- Quadratus Lumborum Block, Abdominoplasty, Analgesia, Locoregional Anesthesia
- Trial name
- QLB (NCT04670224)
- Testing
- QLB anesthesia, Intravenous anesthesia without QLB
- Where
- France
- Volunteers
- 286 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Postoperative Analgesia, Thoracic Surgery
Comparison of Erector Spina Plane Block and Thoracic Paravertebral Block for Analgesia After Thoracotomy
This study aims to compare the postoperative analgesic efficacy of ultrasound-guided erector spinae plane block (ESPB) and thoracic paravertebral block (TPVB) in patients undergoing thoracotomy.
- Trial name
- NCT06778161
- Testing
- nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Elzem SEN
Pain, Post Operative, Cesarean Section Complications
Erector Spinae Plane Block (ESPB) Versus Quadratus Lumborum Block (QLB) for Postoperative Analgesia After Caesarean Section
Management of pain after caesarean section represents an important anesthesiologic issue, since it is often suboptimal, leading to delayed functional recovery and chronic pain.
- Conditions
- Pain, Post Operative, Cesarean Section Complications, Anesthesia, Local, Obstetric Anesthesia Problems
- Trial name
- NCT05348083
- Testing
- ESPB
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Oxycodone
Oxycodone in Combination With Parathoracic Nerve Block is Used for Postoperative Analgesia in Lung Cancer
In this study, the effect of oxycodone combined with ultrasound-guided paravertebral nerve block on the postoperative analgesic effect of thoracoscopic lung cancer was investigated, and the effect and reasonable dose of oxycodone…
- Trial name
- NCT05742256
- Testing
- Oxycodone 1mg/kg, Oxycodone 1.5mg/kg, Sufentanil
- Volunteers
- 159 people
- Sponsor
- Qianfoshan Hospital
Post Operative Pain, Femur Fracture
Volume Dependent Effect of Pericapsular Nerve Block
In PENG block technique, the local anesthetic agent is injected between the psoas tendon and the pubic ramus to block the sensory branches of the nerves which innervates the hip capsule for providing analgesia without causing…
- Trial name
- NCT05256056
- Testing
- Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Postoperative Pain, Gas Bloat Syndrome
The Effect of Kinesio Taping and Breathing Exercises on Pain Management
A randomised clinical trial in a single centre.The aim of this study is to evaluate the effect of kinesio taping and breathing exercises on pain management applied after benign gynecological abdominal operations.
- Conditions
- Postoperative Pain, Gas Bloat Syndrome, Defecation Disorders
- Trial name
- NCT04412122
- Testing
- Kinesio Taping, Breathing Exercise, Kinesio Taping+Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Osteoarthritis, Hip, Hip Osteoarthritis
Intravenous Dexamethasone (0 vs 4 vs 8 mg) as an Adjunct to PENG Block for Postoperative Analgesia in Total Hip Arthroplasty: A Randomized Double-Blind Trial
his study will test whether giving dexamethasone through a vein can improve pain control after total hip replacement surgery. Dexamethasone is commonly used to reduce nausea and may also help with pain, but it is not clear which…
- Trial name
- NCT07581470
- Testing
- Dexamethasone 4mg, Dexamethasone 8mg
- Where
- Poland
- Volunteers
- 198 people
- Sponsor
- Poznan University of Medical Sciences
Pain, Postoperative, Osteoarthritis, Knee
Analgesic Efficacy of Pre-operative Dose of Ketorolac and Gabapentin
Evaluation of the analgesic efficacy of a pre-operative dose of ketorolac and gabapentin in reducing post-operative pain scores in patients undergoing TKA
- Trial name
- NCT07047040
- Testing
- Ketorolac Tromethamine 30 MG/ML Prefilled Syringe, Gabapentin, Empty Medication Capsules
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Assiut University
Acute Pain, Post Operative Pain
Intrathecal Hydromorphone for Postoperative Pain of Anorectal Surgery
Anorectal problems, such as hemorrhoids, fistula, fissures, Etc., often require surgical treatment. Patients often have postoperative pain after these surgeries, which increases discomfort and hospital length of stay.
- Conditions
- Acute Pain, Post Operative Pain, Anorectal Disorder, Analgesia
- Trial name
- IMPAS (NCT05579223)
- Testing
- Intrathecal Hydromorphone Mono Injection
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Post-op Pain
Study to Assess Dopamine Receptor Modulation With Rotigotine to Enhance Morphine Analgesia in the Dental Model
Narcotics are widely used as the mainstay of pain treatment, although increasing doses are required over time as the individual becomes tolerant to their effects.
- Trial name
- NCT02123979
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Breast Diseases
Serratus Posterior Superior Interfascial Plane Block for Breast Surgery
Regional techniques can be used for postoperative pain control following breast surgery. Ultrasound (US) guided serratus posterior superior block (SPSPB) is a new interfacial plane block defined by Tulgar et al in 2023.
- Trial name
- NCT05972083
- Testing
- Analgesia management; group S and C
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Pain, Postoperative
Perioperative Analgesic Efficiency of Quadratus Lumborum Block vs Epidural in Radical Cystectomy
This study is performed to measure the perioperative analgesic efficiency of bilateral quadratus lumborum block versus epidural analgesia in bladder cancer patients undergoing radical cystectomy
- Trial name
- NCT04133051
- Testing
- Quadratus Lumborum Block Using Bupivacaine 0.2%, Epidural Analgesia Using Bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- National Cancer Institute, Egypt
Complications; Cesarean Section
Preoperative Cesarean Section Intravenous Acetaminophen and Postoperative Pain Control
To evaluate the use of maternal opiates for pain control post cesarean delivery in those patients that received intravenous acetaminophen 1000 mg in 150 mL of normal saline, infused 30 minutes prior to incision compared to…
- Trial name
- NCT02694653
- Testing
- Acetaminophen
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Inguinal Hernia Bilateral, Postoperative Pain
M-TAPA vs OSTAP for Postoperative Analgesia in Laparoscopic Inguinal Hernia
This randomized controlled trial aims to compare the postoperative analgesic efficacy of M-TAPA block and OSTAP block in patients undergoing laparoscopic inguinal hernia repair.
- Trial name
- NCT07522853
- Testing
- Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA), Oblique Subcostal Transversus Abdominis Plane Block (OSTAP), Standard Analgesia use (paracetamol, contramal)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Postoperative Pain After Breast Augmentation Surgery, Postoperative Analgesia
Effect of Adding Ultrasound-Guided PECS II Block to Standard Multimodal Analgesia in Breast Augmentation Surgery
This randomized, controlled clinical study will evaluate the effect of an ultrasound-guided PECS II block on postoperative pain control in patients undergoing elective augmentation mammoplasty.
- Trial name
- NCT07879053
- Testing
- Ultrasound-Guided PECS II Block, Standard multimodal analgesia
- Volunteers
- 50 people
- Sponsor
- Ergun Gunduz
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