Clinical trials: Analgesia, Postoperative
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Postoperative Pain, Post Operative Analgesia
Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy
Dexamethasone has been recognized as an antiemetic agent after surgeries, and the combination of dexamethasone and tramadol remained stable in solution up to 5 days. In addition, i.v.
- Conditions
- Postoperative Pain, Post Operative Analgesia, Patient-Controlled Analgesia, Abdominal Surgeries
- Trial name
- DTMPCA (NCT00564603)
- Testing
- Dexamethasone Sodium Phosphate Injection, 0.9% Saline
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Nanjing Medical University
S-ketamine, Esketamine
Safety and Efficacy Evaluation of S (+) - Ketamine in Children
A multicenter, randomized, open-label, active controlled pragmatic clinical trial that evaluates the safety and efficacy of S (+) -ketamine for postoperative acute pain in children in perioperative settings.
- Conditions
- S-ketamine, Esketamine, Acute Pain, Postoperative Pain
- Trial name
- NCT04834427
- Testing
- Conventional therapy + S (+)-Ketamine, Conventional therapy
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Chinese PLA General Hospital
Pain, Postoperative
Randomized Study Comparing the Use of Epidural Analgesia to Intravenous Narcotics for Laparoscopic Colorectal Resection.
Laparoscopic colorectal surgery (LCS) has gained wide acceptance in the treatment of various pathology from diverticular disease to colon cancer.
- Trial name
- NCT02086123
- Testing
- Epidural Analgesia, Parenteral Analgesia (Intravenous)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of California, Irvine
Postoperative Pain
REGIONAL ANALGESIA TECHNIQUES FOR EFFECTIVE RECOVERY TO CORONARY ARTERY BYPASS SURGERIES: A RETROSPECTİVE STUDY IN A SINGLE CENTER EXPERIENCE
Background Pain after cardiac surgery is both multifocal and multifactorial. Sternotomy, sternal retraction, internal mammary dissection, posterior rib dislocation or fracture, possible brachial plexus injury, and mediastinal and…
- Trial name
- NCT05282303
- Testing
- CABG operation
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- V.K.V. American Hospital, Istanbul
Obstructive Sleep Apnea
Multimodal Postoperative Analgesia Following OSA Surgery
Assessment of the clinical efficacy and adverse effects of multimodal analgesic regimen consisting of nalbuphine combined with ketorolac using IV continuous infusion silicon device (Accufuser) for postoperative analgesia…
- Trial name
- NCT04483427
- Testing
- Nalbuphine, ketorolac, accufuser
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Bahaa Mohammed Refaie
Pain, Postoperative
Spinal Morphine for Postoperative Analgesia in Urology
The study was performed in urology patients elicited for open prostatectomy or open nephrectomy. Comparison of analgesic effect between group (M) with spinal morphine before general anaesthesia and group without this intervention…
- Trial name
- NCT03675646
- Testing
- Morphine
- Where
- Czechia
- Volunteers
- 98 people
- Sponsor
- Charles University, Czech Republic
Postoperative Analgesia, Laparoscopic Hysterectomy
Preemptive Analgesia in Laparoscopic Hysterectomy
The aim of this study is to evaluate the effects of ibuprofen and paracetamol administered for pre-emptive analgesia to patients undergoing laparoscopic hysterectomy on pain scores during the first 24 hours postoperatively, the…
- Trial name
- NCT07401927
- Testing
- Ibuprofen, Parasetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Giresun University
Hysterectomy, Myoma
Morphine vs. Oxycodone for Postoperative Pain Management
The purpose of this study is to determine whether oxycodone provides better analgesia compared to morphine after laparoscopic hysterectomy or myomectomy.
- Conditions
- Hysterectomy, Myoma, Postoperative Pain, Opioids
- Trial name
- NCT00528177
- Testing
- Morphine and oxycodone
- Where
- Norway
- Volunteers
- 90 people
- Sponsor
- Ullevaal University Hospital
Injury of Anterior Cruciate Ligament
Adductor Canal Block: Continuous Infusion Versus Automatic Intermittent Bolus
The aim of this prospective, randomized , blinded study is to compare two different infusion techniques (continuous VS intermittent automatic bolus) to assess the effects of postoperative analgesia after Day-Case anterior…
- Trial name
- NCT02589288
- Testing
- Continuous Infusion of ropivacaine 0.2%, Automatic Intermittent Bolus of ropivacaine 0.2%
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- ASST Gaetano Pini-CTO
Acute Pain, Surgery
Clinical Study to Evaluate Clinical Impact of PGx-Guided Treatment for Patients Undergoing Elective Spinal Surgical Procedures
The purpose of this study is to evaluate the effect of pharmacogenetic (PGx) guided treatment when implemented into the pre-operative process for patients undergoing an elective spinal surgical procedure and requiring…
- Trial name
- NCT02599870
- Testing
- NeuroIDgenetix Test Panel
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- AltheaDx
Pain, Postoperative
Bupivacaine Hydrochloride for Pain Control in Cutaneous Surgery
The purpose of this study is to determine if the addition of bupivacaine HCl injections will improve pain control after skin surgery. This is a randomized clinical trial.
- Trial name
- NCT04260854
- Testing
- Bupivacaine Hydrochloride, Saline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postoperative Pain, Dental Implant
Laser Photobiomodulation After Dental Implant Surgery: A Comparison of 650 nm and 810 nm Diode Lasers
The goal of this clinical trial is to evaluate the effectiveness of laser light therapy, known as photobiomodulation (PBM), in reducing pain after dental implant surgery.
- Trial name
- NCT06988722
- Testing
- 650 nm Diode Laser PBM, 810 nm Diode Laser PBM
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Institute of Laser Enhanced Sciences
Pain, Referred
Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section
The purpose of this study is to determine if giving an injection of numbing medication at the incision at the end of cesarean will help control pain AFTER cesarean delivery.
- Trial name
- NCT03383588
- Testing
- Bupivacaine, Morphine, Fentanyl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Pain
Parasternal Nerve Block Using Bupivacaine for Postoperative Analgesia in Children Undergoing Cardiac Surgery
All pediatric patients who undergo cardiac surgery require analgesic medications for postoperative pain control and many require sedation to facilitate comfort with cares.
- Trial name
- NCT02512861
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Postoperative Pain
Efficacy of Tramadol With Ropivacaine for Modified Pectoral Nerve Block in Breast Cancer Surgery
In this study the investigators will compare the post operative opoid consumption for patient undergoing modified radical mastectomy.
- Trial name
- NCT07775053
- Testing
- Pectoral Nerve Block
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sargodha Medical College
Postoperative Pain Management
Multicenter Study for Pediatric Subjects Evaluating Pharmacokinetics and Safety of EXPAREL
Primary Objective: To evaluate the pharmacokinetics (PK) of EXPAREL in pediatric subjects aged 6 to less than 17 years undergoing various types of surgeries.
- Trial name
- PLAY (NCT03682302)
- Testing
- Exparel, 0.5% Bupivacaine HCl
- Where
- 17 sites in United States
- Volunteers
- 98 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Postoperative Pain, Laparoscopic Cholecystectomy
Evaluation of the Efficacy of Regional Anaesthesia for Analgesia After Laparoscopic Cholecystectomy
Postoperative pain is important for patient comfort, wound healing and earlier mobilisation. Different procedures are used by clinicians for this purpose.
- Conditions
- Postoperative Pain, Laparoscopic Cholecystectomy, Regional Anesthesia
- Trial name
- NCT06008002
- Testing
- M-TAPA block, EXORA block, Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Cardiac Surgery Patient, Postoperative Pain
Effect of Intraoperative Morphine on Postoperative Pain After CABG
Ethics committee approval was obtained for this study, which was planned as a prospective, randomized, controlled, single-center trial to be conducted in patients undergoing coronary artery bypass grafting (CABG) surgery between…
- Conditions
- Cardiac Surgery Patient, Postoperative Pain, Pain After Surgery
- Trial name
- NCT07472959
- Testing
- In this study, morphine administration, which is routinely and frequently used in our operating room for patients undergoing CABG, was applied as an additional intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Postoperative, Analgesia
IV Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy
This double-blinded, placebo-control trial clinical trial aims to investigate the effect of IV oxytocin infusion on peri-operative opioid consumption following a minimally invasive hysterectomy under general anesthesia.
- Conditions
- Pain, Postoperative, Analgesia, Postoperative Pain, Pain, Post Operative
- Trial name
- NCT05608070
- Testing
- Oxytocin
- Sponsor
- Beth Israel Deaconess Medical Center
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