Clinical trials: Analgesia, Postoperative
Tonsillectomy
Celecoxib After Tonsillectomy
Tonsillectomy is one of the most common pediatric surgical procedures in the United States. Postoperative pain is substantial, with typical regimens employing narcotic derivatives and acetaminophen for 1-2 weeks after surgery.
- Trial name
- NCT02934191
- Testing
- Celecoxib, Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Children's Hospital of Philadelphia
Postoperative Pain
Effect of Local Anesthetic Infiltration for Postoperative Pain Control in Laparoscopic Abdominal Surgery: A Prospective Randomized Study
Brief Summary Postoperative pain remains a common problem after laparoscopic abdominal surgery despite the minimally invasive nature of these procedures.
- Trial name
- NCT07747584
- Testing
- Bupivacaine, Standard Perioperative Analgesia
- Where
- Pakistan
- Volunteers
- 166 people
- Sponsor
- Allied Hospital Faisalabad
Orthopaedics Wound Dressings
Comparative Efficacy of Advanced and Traditional Wound Dressings in Post-Operative Orthopedic Care
Title: Comparative Efficacy of Advanced and Traditional Wound Dressings in Post-Operative Orthopedic Care: A Randomized Controlled Trial Objective: The primary objective of this study is to evaluate and compare the efficacy of…
- Trial name
- NCT06540040
- Testing
- Aquacel Ag, OPSITE, MEPILEX POST OP BORDER
- Where
- India
- Volunteers
- 320 people
- Sponsor
- Nidhi Srivastava
Kidney Stones
Dual Approach External Oblique Fascial Plane Block Versus Erector Spinae Plane Block for Post Operative Analgesia in Percutaneous Nephrolithotomy
Here is a patient-friendly, ClinicalTrials.gov-compliant Brief Summary written in plain language, avoiding technical jargon as much as possible while remaining accurate.
- Trial name
- BLOCK-PCNL (NCT07359391)
- Testing
- Erector Spinae Plane Block, Dual External Oblique Fascial Plane Block, General Anesthesia
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Pain, Postoperative
Comparative Evaluation of Two Different Post-Operative Analgesia After Hallux Valgus Correction
Background: Recent studies showed the efficiency of several techniques of anesthesia in foot surgery. The new mini-invasive surgical approaches should require less analgesia and rapid motor recovery after surgery.
- Trial name
- NCT03396991
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pain, Postoperative
Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients
This is a prospective, randomized, double-blinded, placebo controlled trial Potential subjects will be identified from the Pre-Surgical Anesthesia Clinic visit.
- Trial name
- IV APAP SF (NCT01394718)
- Testing
- Intravenous Acetaminophen
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Children's Hospital of Philadelphia
Postoperative Pain
Intravenous Paracetamol Compared Dexketoprofen for Postoperative Analgesia After Septoplasty
The investigators conducted a prospective, randomized, double blind study to compare the effectiveness of intravenous paracetamol and dexketoprofen for preventing pain during first 24 hours postoperative period in adult patient…
- Trial name
- NCT02602197
- Testing
- Paracetamol, Dexketoprofen
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baskent University
Pain, Postoperative
Effect of Ketamine on Analgesia Post-Cardiac Surgery
Randomized, controlled, double-blind pilot study evaluating the effect of an intraoperative infusion of intravenous Ketamine on the quantity of opioid consumed postoperatively in coronary artery bypass surgery patients receiving…
- Trial name
- NCT02925858
- Testing
- Normal Saline Flush, 0.9% Injectable Solution_#1, Ketamine Hydrochloride
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Jewish General Hospital
Post Operative Analgesia
Interest of Continuous Ropivacaine Administration Through an Elastomeric Pump (Pain Buster) for the Surgery of Latissimus Dorsi and Serratus Micro Anastomotic Flaps
Continuous bupivacaine administration through an elastomeric pump (Pain Buster) has been found effective for post operative analgesia in a large range of surgery.
- Trial name
- NCT00724685
- Testing
- Naropeine (Ropivacaine)
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Nantes University Hospital
Pain, Postoperative
Local Analgesia to Prevent Pain in Patient Undergoing Removal of the Uterus Through Vaginal Route
Following a hysterectomy, women tend to experience high levels of pain, and many require strong pain killers after the procedure.
- Trial name
- NCT03099720
- Testing
- Ropivacaine
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Cholecystitis, Cholecystitis, Acute
M-Tapa Block vs External Oblique Intercostal Block for Laparoscopic Cholesistectomy
Ultrasound (US)-guided Modified Perichondral Approach Thoracoabdominal Nerve (M-TAPA) block is a novel block that provides effective analgesia in the anterior and lateral abdominal walls after laparoscopic surgery, and local…
- Trial name
- NCT05502159
- Testing
- M-TAPA, EOB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Surgery
Collecting Outcomes and Managing Pain After Surgery
The primary aim of this study is to measure pain and psychosocial patient reported outcomes, objective functionality, and actual daily at home opioid usage in orthopedic patients.
- Trial name
- COMPAS (NCT03834818)
- Testing
- COMPAS Participants
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Duke University
Hernia
EXPAREL Infiltrated Into the TAP for Postoperative Analgesia in Unilateral Abdominal Hernia Repair
Phase 4 study evaluating the effectiveness of EXPAREL when infiltrated into the the Transversus Abdominis Plane (TAP).
- Trial name
- 702 (NCT01801124)
- Testing
- EXPAREL
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Pain Postoperative
Pregabalin and Analgesia After Laparoscopic Cholecystectomy
The purpose of this study is to evaluate how effective is the preoperative administration of pregabalin 600mg, to attenuate postoperative pain and opioids consumption after laparoscopic cholecystectomy.
- Trial name
- NCT01321801
- Testing
- Pregabalin
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Larissa University Hospital
Nausea, Vomiting
Effect of Dexamethasone Combined With Ondansetron on Postoperative Nausea and Vomiting in Patients With Patient-controlled Analgesia After Video-assisted Thoracoscopic Surgery
The purpose of this study is to study the effect of dexamethasone combined with ondansetron on postoperative nausea and vomiting in patients with patient-controlled analgesia after video-assisted thoracoscopic surgery.
- Trial name
- NCT01007500
- Testing
- Dexamethasone, Ondansetron
- Where
- South Korea
- Volunteers
- 123 people
- Sponsor
- Yonsei University
Pain
Postoperative Analgesic Effects of Dexmedetomidine for Transversus Abdominis Plane Block
the aim of this study is evaluate postoperative analgesic effects of dexmedetomidine added to bupivacaine on TAP block in patients undergoing lower abdominal surgery.
- Trial name
- TAP (NCT02064530)
- Testing
- Bupivacaine, Dexmedetomidine, serum physiologic
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University
Mastectomy, Nerve Block
Effect of Pectoralis Block on Analgesia After Simple Mastectomy
The pectoralis block, including pecs I and II block, is a novel technique first described in 2011 as an alternative to paravertebral blockade for analgesia following breast surgery.
- Conditions
- Mastectomy, Nerve Block, Analgesia, Postoperative
- Trial name
- NCT03143530
- Testing
- Pectoralis block, Normal saline injection, Ropivacaine Injection
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Cholecystectomy, Laparoscopic, Cholecystectomy, Robotic
Opiranserin for Minimally Invasive Cholecystectomy
The purpose of this study is to evaluate whether the combination therapy of opiranserin and acetaminophen is non-inferior to the combination of non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen for postoperative…
- Trial name
- NCT07620665
- Testing
- Opiranserin+Acetaminophen, Acetaminophen+NSAIDs
- Where
- 2 sites in South Korea
- Volunteers
- 88 people
- Sponsor
- Gangnam Severance Hospital
Arthroplasty, Replacement, Knee, Pain, Postoperative
BiFeS vs. iPACK in Postoperative Knee Arthroplasty Analgesia
The Biceps Femoris Short Head (BiFeS) block is a new fascial plane block technique targeting the sensory innervation of the posterolateral capsule of the knee while preserving motor function.
- Conditions
- Arthroplasty, Replacement, Knee, Pain, Postoperative, Anesthesia, Regional
- Trial name
- NCT07360392
- Testing
- Biceps Femoris Short Head Block (BiFeS), Infiltration Between The Popliteal Artery and The Capsule of The Knee, Adductor Canal Block
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Amasya University
Postoperative Pain Management
Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Plus Biceps Femoris Short Head Block in Patients Undergoing Knee Arthroscopy
This prospective, randomized, controlled, and multicenter clinical study aims to compare the postoperative analgesic efficacy of two regional anesthesia techniques commonly used in knee arthroscopy: adductor canal block (ACB) and…
- Trial name
- bifes knee (NCT07242339)
- Testing
- Adductor Canal Block (ACB) Only, biceps femoris short head block + Adductor Canal Block (ACB)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
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