Clinical trials: Analgesia Post Fracture
Hip Fracture of Intertrochanteric Type
Postoperative Analgesia With Local Infiltration After Hip Fracture Of Intertrochanteric Type
Reducing pain is an essential factor for early mobilization after osteosynthesis of intertrochanteric fractures. Systemic opioids have side effects that might obstruct mobilization and induce delirium and nausea.
- Trial name
- NCT01119209
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 74 people
- Sponsor
- Odense University Hospital
Discectomy, Vertebral Fractures
Comparative Study Between ESPB Versus IV Morphine as Postoperative Analgesia After Spine Surgeries .
Postoperative pain is often severe in patients undergoing lumbar surgery. Due to postoperative pain, patients are unwilling to get out of bed at an early stage, which affects their recovery.
- Trial name
- NCT05350696
- Testing
- Erector Spinae plane block (plain pubivicaine), Intravenous morphine group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Rib Fractures, Wounds and Injuries
Comparison of Epidural and Paracostal Catheter Placement for Pain Control After Rib Fractures
The investigators plan to compare the incidence of successful placement of epidural pain catheters versus paracostal catheters for the control of pain and prevention of pulmonary complications for adult trauma patients with blunt…
- Trial name
- NCT02295098
- Testing
- Thoracic epidural catheter placement, Paracostal catheter placement
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Colorado, Denver
Elderly, Hip Fracture Surgery
Dexmedetomidine Supplemented Analgesia and Delirium After Hip Fracture Surgery
Delirium is common in the elderly after hip fracture surgery, and is associated with worse outcomes. The investigators hypothesize that, for elderly patients after hip fracture surgery, dexmedetomidine supplemented analgesia can…
- Conditions
- Elderly, Hip Fracture Surgery, Patient-controlled Analgesia, Dexmedetomidine
- Trial name
- NCT04955249
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Peking University First Hospital
Lower Extremities Fracture
Comparison Between Dexamethasone and Morphine as an Adjuvant to Bupivacaine for Post-operative Analgesia
The study aimed to compare the effectivity of dexamethasone 8 mg and morphine 2 mg as an adjuvant to epidural bupivacaine 0,125% 12,5mg for post-operative analgesia in lower extremities.
- Trial name
- NCT03051022
- Testing
- Dexamethasone 8 mg, Morphine 2 mg
- Where
- Indonesia
- Volunteers
- 64 people
- Sponsor
- Universitas Indonesia
Tibial Plateau Fracture, Pain, Postoperative
Saphenous Nerve Block After Tibial Plateau ORIF
Fractures of the tibial plateau, while very painful, typically do not receive nerve blocks. This is because of a concern that the numbness from a nerve block would "mask" the typically painful symptoms of compartment syndrome, a…
- Trial name
- NCT04314570
- Testing
- Saphenous Nerve Block with Ropivacaine Treatment, Saphenous Nerve Block with Saline Control
- Sponsor
- Stanford University
Fractures, Closed, Pain, Postoperative
Pain and Narcotic Usage After Orthopaedic Surgery
This study aims to 1) observe the course of pain, 2) utilization of opioid pain medication, and 3) possible effect of a behavioral intervention delivered via an automated mobile phone messaging robot in patients undergoing…
- Conditions
- Fractures, Closed, Pain, Postoperative, Pain Catastrophizing, Pain, Acute
- Trial name
- NCT03991546
- Testing
- Acceptance and Commitment Therapy Delivered via an Automated Mobile Messaging Robot
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Christopher Anthony
Supracondylar Humerus Fracture
NSAIDs vs Opioids for Post-op Pain in Supracondylar Humerus Fractures
The purpose of this study is to determine if using the combination of acetaminophen (also known as Tylenol) and ibuprofen (also known as Motrin or Advil) will provide equal or better pain control as compared to…
- Trial name
- NCT04905563
- Testing
- Acetaminophen-Hydrocodone, Acetaminophen and Ibuprofen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Le Bonheur Children's Hospital
Pain, Postoperative
The Effect of Femoral Nerve Block on Opioid Requirements After Surgery for a Femur Fracture in Children
This study evaluates the effect of a femoral nerve block on opioid requirements following femoral fracture fixation with flexible nails in the paediatric population. This is a double blind, prospective randomized clinical trial.
- Trial name
- NCT00175591
- Testing
- Administration of a femoral nerve block (bupivacaine HCL)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of British Columbia
Femoral Neck Fracture
Fascia Iliaca Block in the Emergency Department for Analgesia After Femoral Neck Fracture
Femoral neck fracture is very common in the elderly and can produce severe to moderate pain. As this pathology is not life-threatening, waiting time in the emergency department may be prolonged due to the high number of…
- Trial name
- NCT02433548
- Testing
- Fascia iliaca block
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Rib Fractures
Early Percutaneous Cryoablation for Pain Control After Rib Fractures Among Elderly Patients
The purpose of this study is to provide long-term pain control for elderly patients with rib fractures in order to minimize their risk of complications and return them to baseline functional capacity
- Trial name
- EPERC (NCT04482582)
- Testing
- Cryoneurolysis, Standard of Care
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Stanford University
Orthopedic Surgery of Lower Extremity
Evaluation of Continuous Saphenous Nerve Block to Supplement a Continuous Sciatic Nerve Block After Ankle Surgery
A nerve block catheter is a small tube placed next to a nerve through a needle, and the needle is then removed. Numbing medicine is dripped through the tube to reduce pain sensation from the nerve.
- Trial name
- NCT01167907
- Testing
- 0.2% ropivacaine, saline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Wake Forest University Health Sciences
Post-operative Pain Management, Hip Fracture Surgery
Comparison of Analgesic Efficacy of PENB Block with FICB in Post Operative Hip Fracture Patients
This study was done to evaluate two different interventions for postoperative pain control in patients undergoing hip surgeries. Fifty patients, divided in two equal groups, were included in the study.
- Trial name
- NCT05810012
- Testing
- PENG block, FICB Block
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Pain Medicine Department
Orthopedic Procedures, Arthroplasty
Post Surgical Multimodal Analgesia With Oral Strong Opioids
This is a prospective observational case study, focusing on the clinical effectiveness of oral strong opioids for pain management following common orthopedic surgeries.The study aims to evaluate the effectiveness of multimodal…
- Conditions
- Orthopedic Procedures, Arthroplasty, Fracture Fixation
- Trial name
- ORORA (NCT06554457)
- Testing
- Multimodal analgesia with oral strong opioids
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Pain Management
Local Anesthesia for Facial Fractures
The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics.
- Trial name
- LAFF (NCT06429501)
- Testing
- Bupivacaine/Epinephrine, Saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Femoral Neck Fractures, Femur Head Necrosis
Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG)
The goal of this clinical trial is to study the analgesic effect of liposomal bupivacaine plus bupivacaine for Pericapsular Nerve Group (PENG) block in postoperative pain management following hip replacement surgery.
- Conditions
- Femoral Neck Fractures, Femur Head Necrosis, Hip Fractures
- Trial name
- PENG (NCT06565910)
- Testing
- Liposomal bupivacaine plus bupivacaine, Ropivacaine
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Huazhong University of Science and Technology
Distal Radius Fractures
Mechanical Modalities vs. Standard Care for Edema and Pain Management After DRF Fixation
This single-blinded, randomized controlled trial (RCT) will evaluate the added benefit of mechanical modalities (continuous passive motion (CPM) and intermittent pneumatic compression (IPC)) when integrated into standard therapy…
- Trial name
- NCT06913920
- Testing
- Continuous Passive Motion (CPM), Intermittent Pneumatic Compression (IPC), Standard Therapy Program
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al Hayah University In Cairo
Closed Non Comminuted Long Bone Fractures
Continuous Lornoxicam Infusion for Orthopaedic Surgery
Perioperative continuous infusion of lornoxicam would be an effective and safe regimen to reduce the patient controlled morphine consumption after orthopaedic surgery.
- Trial name
- NCT01718756
- Testing
- Continuous infusion, Scheduled
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University
Femoral Neck Fracture
Postoperative Analgesia With Local Infiltration After Femoral Neck Fracture
Reducing pain is an essential factor for early mobilization after osteosynthesis of femoral neck fractures. Systemic opioids have side effects that might obstruct mobilization and induce delirium and nausea.
- Trial name
- NCT00529425
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Distal Radius Fracture, Pain Management
Narcotic Versus Non-narcotic Medication for Pain Management After Wrist/Hand Fractures
The purpose of this study is to evaluate two drug options for pain control in patients following wrist injury. Participants will be randomized to one of the 2 pain relief treatments to determine what treatment provides the most…
- Conditions
- Distal Radius Fracture, Pain Management, Metacarpal Fracture
- Trial name
- NCT03375593
- Testing
- Hydrocodone 5Mg/Acetaminophen 500Mg Tab, Acetaminophen 500Mg Tab, Ibuprofen 600 mg tab
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's