Clinical trials: Anaphylaxis Food
Food Hypersensitivity, Peanut Hypersensitivity
Mechanisms Underlying Peanut Allergic Reactions in TRACE Peanut Study Participants: Extension Study
Food allergy affects up to 10% of the population. The mainstay of management involves dietary avoidance and provision of rescue medication in the event of an accidental reaction.
- Trial name
- TRACEextension (NCT02665793)
- Testing
- DBPCFC to peanut cookie, Single-dose DBPCFC to peanut flour, Single-dose DBPCFC to peanut butter
- Volunteers
- 17 people
- Sponsor
- Imperial College London
Peanut Hypersensitivity
The Effect of Extrinsic Factors on Food Allergy
Food allergy is a common problem, affecting 5-8% of the population. Peanut allergy causes reduced quality of life due to the perceived high risk of severe reactions.
- Trial name
- Ex-Factor (NCT01429896)
- Testing
- Food challenge
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Anaphylactic Reaction, Anaphylaxis
Steroid Use in Treatment of Allergic Reactions to Food
In this study, the investigators want to find out whether a specific medication commonly used for severe allergic reactions is really necessary.
- Conditions
- Anaphylactic Reaction, Anaphylaxis, Allergy in Children, IgE Mediated Food Allergy
- Trial name
- SAFARI (NCT07341776)
- Testing
- Antihistamines, Systemic corticosteroids, Adrenaline (rescue medication)
- Where
- 2 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Johannes Trueck
Peanut Allergy, Peanut Hypersensitivity
A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy
The overall aims of this study are to demonstrate that treatment with PVX108 immunotherapy has an acceptable safety profile and is effective for reducing clinical reactivity to peanut protein in children and adolescents with…
- Conditions
- Peanut Allergy, Peanut Hypersensitivity, Peanut-Induced Anaphylaxis, Immune System Diseases
- Trial name
- NCT05621317
- Testing
- PVX-108
- Where
- 14 sites in United States, Australia
- Volunteers
- 90 people
- Sponsor
- Aravax Pty Ltd
Peanut and Tree Nut Allergy
Accidental Reactions in Peanut/Tree Nut Allergic Children
Food allergy is an immune reaction, triggered by food protein allergens, of varying severity, from mild local reaction to life threatening anaphylaxis and fatalities.
- Trial name
- ALLERGY (NCT05671471)
- Where
- France
- Volunteers
- 147 people
- Sponsor
- University Hospital, Lille
Food; Allergy, Anaphylactic Shock, Asthma in Children
Omalizumab in Severe Asthmatics With Food Allergy
A prospective assessment of the impact of Omalizumab in terms of efficacy, safety, and quality of life (FA-QoL) in patients with moderate/severe asthma and history of anaphylaxis to peanut, tree nuts, fish, egg, milk, and/or…
- Trial name
- OSAFA (NCT06316414)
- Testing
- Omalizumab
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Peanut Allergic Subjects
Peanut Oral Immunotherapy in Children With Peanut Allergy (Peanut Flour)
Many children who are allergic to peanuts do not outgrow their allergy and have very severe allergic reactions called anaphylaxis.
- Trial name
- PeanutFlour (NCT02203799)
- Testing
- Peanut Oral Immunotherapy (POIT)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Baylor College of Medicine
Food Hypersensitivity, Immune System Diseases
Oral Immunotherapy in Food Allergy in Finland
The outcomes of oral immunotherapy (OIT) in food allergy study will provide more knowledge of oral immunotherapy. So far the OIT has showed in clinical experiments to be a interesting way to increase the unresponsiveness in…
- Conditions
- Food Hypersensitivity, Immune System Diseases, Anaphylaxis
- Trial name
- NCT02640014
- Testing
- Milk
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- Helsinki University Central Hospital
Wheat Allergy, Anaphylaxis Food
Major Allergen in Wheat Anaphylaxis in Thai Population
To study Major allergen in Wheat anaphylaxis in Thai population To study and compare demographic data between group of wheat anaphylaxis
- Conditions
- Wheat Allergy, Anaphylaxis Food, Anaphylaxis Exercise
- Trial name
- NCT03487315
- Testing
- immunoblot
- Where
- Thailand
- Volunteers
- 36 people
- Sponsor
- Mahidol University
Food Allergy, Anaphylaxis Food
Inhibition of Anaphylaxis by Ibrutinib
This is a phase II open label study on the use of Ibrutinib on the inhibition of food-induced anaphylaxis in adults with food allergy.
- Trial name
- NCT03149315
- Testing
- Ibrutinib
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Eczema, Egg Allergy
Promoting Tolerance to Peanut in High-Risk Children
This study will evaluate whether early exposure to peanuts promotes tolerance and provides protection from developing peanut allergy in children who are allergic to eggs or who have severe eczema.
- Conditions
- Eczema, Egg Allergy, Food Allergy
- Trial name
- LEAP (NCT00329784)
- Testing
- Peanut Consumption Group
- Where
- United Kingdom
- Volunteers
- 640 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Idiopathic Anaphylaxis, Drug Anaphylaxis
Cause of Unexplained Anaphylaxis
This study will explore the possible cause of unexplained, or idiopathic, anaphylaxis. Anaphylaxis is a rapid, life-threatening, severe reaction that occurs suddenly after contact with an allergy-causing substance, usually a…
- Conditions
- Idiopathic Anaphylaxis, Drug Anaphylaxis, Venom Anaphylaxis, Food Anaphylaxis
- Trial name
- NCT00719719
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Fish Allergy, Food Hypersensitivity
FASC: Fish Allergy in Spanish Children - A Study of New Cases of Fish Allergy in Children and Adolescents
Fish allergy is one of the leading causes of food-induced allergic reactions in children, but the clinical presentation and patterns of sensitization vary considerably among patients and geographical regions.
- Conditions
- Fish Allergy, Food Hypersensitivity, IgE-Mediated Food Allergy
- Trial name
- FASC (NCT07727148)
- Volunteers
- 120 people
- Sponsor
- Carmelo Escudero
Food Hypersensitivity, Anaphylaxis
A Registry for the Food Allergy Community
The FARE Patient Registry will serve as a prospective, observational food allergy reporting system that stores detailed health and other basic information about patients' real-world experiences with food allergies, to encourage…
- Conditions
- Food Hypersensitivity, Anaphylaxis, Eosinophilic Esophagitis, Food Sensitivity
- Trial name
- FPR (NCT04653324)
- Where
- United States
- Volunteers
- 23,000 people
- Sponsor
- Food Allergy Research & Education
Food Allergy
One-year Survey of Anaphylaxis in Outpatient Children Allergic to Peanuts, Walnuts/Hazelnuts, Shellfish
In Italy, few data about anaphylaxis due to peanuts in pediatric age are available, conversely data about walnuts/hazelnuts, shellfish/mollusks anaphylaxis have not yet been collected.
- Trial name
- NCT02640560
- Testing
- Food allergy questionnaire, Control Questionnaire
- Volunteers
- 200 people
- Sponsor
- Stefania La Grutta, MD
Peanut Hypersensitivity, Anaphylaxis
PEAnut Anaphylaxis Predictors
Peanut allergy can be life-threatening. Current diagnostic techniques for peanut allergy have high sensitivity, but not high specificity.
- Trial name
- PEAAP (NCT02424136)
- Testing
- Questionnaire, Peanut Skin prick test, Fraction of exhaled nitric oxide
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- John Hunter Children's Hospital
Milk Allergy, Anaphylaxis
Safety of Oral Immunotherapy for Cow's Milk Allergy in School-aged Children
The purpose of this study is to study the number of Participants with Adverse Events as a Measure of Safety and Tolerability.
- Trial name
- NCT01361347
- Testing
- milk
- Where
- Finland
- Volunteers
- 28 people
- Sponsor
- Tampere University Hospital
Food Allergy, Anaphylaxis
Potential Allergens in Wine: Double-blind Placebo-controlled Trial
This study is designed to identify whether wines which are produced using the common potential food allergens such as proteins derived from fish, milk or egg are likely to contain sufficient food allergens to cause allergic…
- Trial name
- NCT00163735
- Testing
- Administration of wine fined with potential food allergens
- Where
- Australia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Allergy, Peanut, Peanut Allergy
Evaluating the Safety and Efficacy of Oral Encapsulated Microbiota Transplantation Therapy in Peanut Allergic Patients
This is a phase II trial that aims at evaluating the safety and tolerability of oral encapsulated fecal microbial transplantation therapy (MTT) in peanut allergic patients.
- Conditions
- Allergy, Peanut, Peanut Allergy, Peanut Hypersensitivity, Peanut-Induced Anaphylaxis
- Trial name
- NCT05695261
- Testing
- Microbial Transplantation Therapy, Antibiotic, Oral Immunotherapy (OIT)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Rima Rachid
Food Allergy
Registry of Food Allergy Oral Immunotherapy Treatment
The purpose of this patient registry is to demonstrate safety and efficacy of food oral immunotherapy in food allergic patients. Factors that lead to adverse reactions will be identified.
- Trial name
- NCT03059589
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Food Allergy Support Team