Clinical trials: Anatomical Pathological Condition
Sarcopenia
Effect of an EAA/Whey Composition on Protein Metabolism
Sarcopenia, a progressive loss of muscle mass, strength and function, is an inevitable natural process of aging. While it may be impossible to completely reverse the progress of sarcopenia, it is well established that intake of…
- Trial name
- NCT03502941
- Testing
- 6.3 g of EAAs mixture and whey protein isolate, 12.6 g of EAAs mixture and whey protein isolate, 12.6 g of whey protein isolate
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Healthy Volunteer, Muscular Atrophy, Spinal
Ability of Muscle Imaging and Motor Function Measure (MFM) to Detect Changes in Disease Progression in Ambulant Spinal Muscular Atrophy Patients Compared to Healthy Volunteers.
This non-drug, single center, 24-week, longitudinal study in ambulant spinal muscular atrophy (SMA) patients and in age- and gender-matched healthy volunteers will assess the detection of disease progression by magnetic resonance…
- Trial name
- NCT02044029
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Sarcopenia, Muscle Loss
Effect of Strength Training and Protein Ingestion in Old Versus Very-old
From 3 interventiongroups in the project with ClinicalTrials.gov ID NCT02034760, namely: HRTW: Heavy Strength Training x3/week \& 20g whey protein twice daily.
- Trial name
- NCT02105922
- Testing
- Heavy Resistance Training, Light Intensity Training, Protein Whey
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Pelvic Anatomy, Retroperitoneum
Systematic Anatomical Description of the Female Pelvic Retroperitoneum in Cadavers
This observational descriptive cadaveric study aims to describe the main anatomical relationships of the female pelvic retroperitoneum using standardized anatomical dissection.
- Conditions
- Pelvic Anatomy, Retroperitoneum, Cadaveric Study, Surgical Anatomy
- Trial name
- RETRO-PELVIS (NCT07522931)
- Testing
- Anatomical Dissection
- Where
- 2 sites in Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari de Bellvitge
Sarcopenia, Liver Cirrhosis
Microbiome and Sarcopenia in Patients With Liver Cirrhosis
Protein-energy malnutrition (PEM) occurs in 65-90% of patients with liver cirrhosis. Severity of malnutrition correlates with progression of liver disease and leads to sarcopenia in 30-70% of cirrhotic patients.
- Trial name
- NCT03080129
- Testing
- Fresubin energy
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Alzheimer's Disease (AD), Neurodegenerative Disease
A Biomarker-chip Assay in Preserved Red Blood Cells for the Diagnosis of Alzheimer's Disease
The ADCHIP study (ST0067) is a non-interventional, monocentric, prospective study conducted by Amoneta Diagnostics and the Leenaards Memory Center (Lausanne, Switzerland).
- Conditions
- Alzheimer's Disease (AD), Neurodegenerative Disease, Dementia, Frontotemporal Dementia (FTD)
- Trial name
- ADCHIP (NCT07307872)
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Amoneta Diagnostics SAS
Hysteroscopy, Minimally Invasive Surgical Procedures
Implementation of Hysteroscopy in Flanders and the Netherlands
By means of a questionnaire the investigators will study the implementation of hysteroscopy in Flanders and the Netherlands
- Conditions
- Hysteroscopy, Minimally Invasive Surgical Procedures, Polyp, Myoma
- Trial name
- NCT02853695
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- University Ghent
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Fibrosis, Scarring
High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin
The goal of this study is to establish the safety of high fluence LED-RL from 160 J/cm2 up to 640 J/cm2 in healthy subjects. The hypothesis is that high fluence LED-RL phototherapy is safe in human skin.
- Conditions
- Fibrosis, Scarring, Scar, Wounds
- Trial name
- NCT02630303
- Testing
- LED-RL Phototherapy, Mock Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jared Jagdeo, MD, MS
Calculus, Dental, Periodontal Diseases
Development of a New Toothpaste for the Removal of Dental Calculus.
Periodontal disease is amongst the most prevalent oral diseases worldwide and in North America. According to the 2007/09 Canadian Health Measures Survey, 16% of Canadian adults and 24% of older adults, 60 to 79 years of age, were…
- Conditions
- Calculus, Dental, Periodontal Diseases, Periodontal Inflammation
- Trial name
- NCT04381403
- Testing
- Bio-descaling D-Tart toothpaste, Crest® toothpaste
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Faleh Tamimi
Nerve Block, Anesthesia, Local
Cutaneous Anesthesia of the Lateral Femoral Cutaneous Nerve
The purpose of this study is to investigate and describe the anatomical differences in distribution of the blocked area following a perineural LFCN (Lateral Femoris Cutaneous Nerve) block with either 8 ml or 16 ml of Ropivacaine…
- Conditions
- Nerve Block, Anesthesia, Local, Pain, Postoperative, Anatomical Distribution
- Trial name
- NCT03138668
- Testing
- Ropivacaine Injection
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Cancer of Skin, Cancer of Kidney
Low-moderate Intensity Pedaling During Immunotherapy Administration
The purpose of this study is to determine the feasibility pedaling using an under-the desk bike during immunotherapy infusions. Also, the study hopes to evaluate how pedaling impacts quality of life and treatment response…
- Conditions
- Cancer of Skin, Cancer of Kidney, Cancer of Bladder, Exercise, Aerobic
- Trial name
- NCT04127318
- Testing
- Pedaling Group
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Low Back Pain
Serum Cytokine Levels in Patients with Lumbal Disc Herniation and Effectiveness of Exercise
The aim of the study is to investigate serum cytokine levels and the efficacy of lumbar stabilization exercises in patients with lumbar disc herniation with and without neurological deficits.
- Trial name
- NCT04912388
- Testing
- Lumbal stabilization excercises, Conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Alzheimer's Disease
CNS and Plasma Amyloid-Beta Kinetics in Alzheimer's Disease
Alzheimer's disease (AD) is the most common cause of dementia and currently has no disease modifying treatments or simple accurate diagnostic tests.
- Trial name
- NCT02021682
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Muscle Wasting, Protein Intake
Effects of Ketones on Muscle Wasting During Caloric Restriction in Lean Females
Because of these anabolic properties of ketone bodies and the fact that ketone bodies prevent muscle protein breakdown for gluconeogenesis during energetic stress, ketone bodies can be a promising strategy to prevent or treat…
- Conditions
- Muscle Wasting, Protein Intake, Ketosis, Caloric Restriction
- Trial name
- NCT04744142
- Testing
- Ketone supplementation, Increased protein intake
- Where
- Belgium
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Uterine Prolapse
Randomized Controlled Trial Comparing Acellular Collagen Biomesh (Pelvisoft) to Polypropylene Mesh(Pelvitex) for Sacral Colpopexy
This research protocol is a randomized controlled trial. It is being done to compare and find out the relative differences between the materials, (Pelivisoft) "natural organic mesh" to poly propylene mesh (Pelvitex) "manmade…
- Trial name
- NCT00564083
- Testing
- sacral colpopexy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Prolapse
Affixing Polypropylene Mesh Using Barbed Suture (Quill™ Srs) During Laparoscopic Sacrocolpopexy Randomized Controlled Trial (Quill Lsc)
1.0 STUDY OBJECTIVE 1.1 PRIMARY OBJECTIVE - To compare two methods of polypropylene mesh attachment during laparoscopic sacrocolpopexy (LSC): running technique using self-anchoring 1 barbed delayed absorbable suture (Quill™ SRS…
- Trial name
- QUILL-LSC (NCT01551992)
- Testing
- Quill suture vs. Interrupted suture
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Antibiotic Prophylaxis, Wound Infection
The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients
This study aims to investigate the impact of antibiotic prophylaxis on reducing wound infection rates following open repair of primary elective groin hernias in high-risk patients.
- Conditions
- Antibiotic Prophylaxis, Wound Infection, Groin Hernia
- Trial name
- NCT06576154
- Testing
- Cefazolin 1000 MG
- Where
- Syria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Alopecia, Androgenetic
Role of Vitamin D in Androgenetic Alopecia
Androgenetic alopecia is a common form of diffuse hair loss in both men and women,It primarily affects the top and front of the scalp with different clinical presentations and there are numerous classification systems for grading…
- Trial name
- NCT03154528
- Testing
- serum vitamin D level by ELISA
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetes, Plaque
DD2-Coronary Plaque Morphology and Plaque Progression
However, there is only very sparse information regarding the atherosclerotic burden and cardiovascular biomarkers in the early stages of type-2 diabetes, as the vast majority of studies have concerned diabetes populations with…
- Conditions
- Diabetes, Plaque, Atherosclerosis
- Trial name
- DD2plaque (NCT03022344)
- Testing
- Cardiac CT
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark