Clinical trials: Anesthesia, Epidural
Labor Pain
Use of Standardized Algorithm for the Management of Epidural Analgesia for Labor and Delivery
Programmed Intermittent Epidural Bolus (PIEB) has become a standard technique for labour analgesia in many departments of anesthesia.
- Trial name
- NCT04814199
- Testing
- Algorithm
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pain, Postoperative, Adverse Reaction to Epidural Anesthesia
Pediatric Caudal Anesthesia Block. And Pain Control
Caudal epidural block CEB is the most commonly performed neuraxial block to provide effective pain relief and analgesia in patients undergoing infra-umbilical pediatric surgery.
- Conditions
- Pain, Postoperative, Adverse Reaction to Epidural Anesthesia, Anesthesia, Caudal
- Trial name
- CEB (NCT05581940)
- Testing
- Group A Caudal Epidural Anesthesia with bupivacaine 0.25% and group B with opioid intervenors
- Where
- Bahrain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Labor Pain
Parturient Controlled Epidural Analgesia (PCEA) With or Without a Basal Infusion for Early Labor
Patient Controlled Epidural Analgesia is a widely used and effective means of adult pain management. However, Parturient Controlled Epidural Analgesia (PCEA) is a relatively new approach to pain control for the women in labor.
- Trial name
- NCT00871442
- Testing
- No Basal Infusion, Basal infusion, PCEA solution (bupivacaine and fentanyl)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neil Roy Connelly, MD
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Influence of Maternal Postioning on Spread of Local Anesthetic After Epidural Analgesia
The purpose of this study is to determine if a lateral positioning of the pregnant woman after epidural analgesia increases the incidence of unilateral functioning epidurals.
- Trial name
- NCT02617823
- Testing
- lateral position
- Where
- 2 sites in Sweden
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Region Skane
Epidural Space Depth
Ultrasound Guidance for Epidural Analgesia and Anesthesia
Most women delivering by cesarean at BC Women's receive regional anesthesia; which includes spinal, epidural, or combined spinal-epidural anesthesia.
- Trial name
- NCT02436109
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Epidural Analgesia, Postoperative Pain
Comparison of the Incidence of Inadequate Epidural Analgesia Between Protocol Based and Current Practice
Epidural analgesia is the recommended analgesic technique in patients having surgery with severe postoperative pain such as thoracic and upper abdominal surgery.
- Trial name
- NCT04111406
- Testing
- Current practice, Protocol based
- Where
- Thailand
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pleural Effusion, Malignant, Pleural Mesothelioma
A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia
Video-assisted thoracic surgery (VATS) is usually performed with general anesthesia and single lung ventilation. However, performing thoracic surgery under awake regional anesthesia has several potential advantages including…
- Conditions
- Pleural Effusion, Malignant, Pleural Mesothelioma, Pleural Empyema, Pulmonary Diseases or Conditions
- Trial name
- VATS (NCT05077111)
- Testing
- Thoracic Epidural Anesthesia, General Anesthesia with One Lung Ventilation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mohamed Reda Ashour
Labor Pain
Changes in Velocimetric Indices of Uterine and Umbilical Arteries Before and After Combined Spinal-epidural Analgesia in Laboring Women
Combined spinal-epidural (CSE) for labor analgesia has been used for many years and is practiced commonly at our institution, especially when the patient requests immediate pain relief.
- Trial name
- NCT05512065
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Post-dural Puncture Headache, Post-dural Puncture Backache
Long-term Effects of Accidental Dural Puncture in Patients Having Had an Epidural Blood Patch (LEAP)
Accidental dural puncture (ADP) during placement of an epidural catheter for anesthesia and analgesia is a well known complication. Previous studies have found audiometric deterioration following ADP.
- Trial name
- LEAP (NCT02149680)
- Where
- 2 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Postoperative Pain After Total Knee Arthroplasty, Postoperative Pain
Postoperative Pain and Analgesic Use After Total Knee Arthroplasty
This prospective observational study evaluates postoperative pain intensity and analgesic consumption in patients undergoing total knee arthroplasty (TKA) under different anesthesia techniques.
- Conditions
- Postoperative Pain After Total Knee Arthroplasty, Postoperative Pain, Analgesic Consumption
- Trial name
- NCT07457814
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Labouring Parturients Requiring/Requesting Epidural Analgesia as Part of Their Peri-partum Care
A Comparison Study Of Two Different Techniques For Identifying The Epidural Space In Parturients In Labour
The purpose of this study is to determine whether the use of the Epidrum device to identify the epidural space in labouring parturients reduces morbidity, when compared to standard loss of resistance techniques.
- Trial name
- NCT01574391
- Testing
- Epidrum
- Where
- Ireland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Maternity Hospital, Ireland
Labor Pain
Does Ultrasound Scanning of the Lumbar Spine Improve Patient Satisfaction and the Ease of Insertion Epidurals?
Ultrasound scanning of the back has been shown to increase success when used to guide epidural catheter insertion. However, this technique is not applied widely in clinical practice.
- Trial name
- NCT00996905
- Testing
- Portable ultrasound machine
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Pain
CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens
Analgesia in labour is not readily available in many parts of Sub-Saharan Africa. The overall cost of Epidural services in terms of human personnel and financial implication makes this inaccessible to many women in labour.
- Trial name
- SSS (NCT03117595)
- Testing
- Bupivacaine-fentanyl, Bupivacaine-fentanyl morphine
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Beckley
Acute Postoperative Pain
Ultrasound Guided Bilateral Erector Spinae Block Versus Caudal in Lumbar Spine Surgeries
Major lumbar spine surgeries are associated with severe postoperative pain that usually lasts for at least 3 days.Caudal epidural analgesia has a crucial role in providing effective pain relief post lumbar spine surgeries by…
- Trial name
- NCT05351203
- Testing
- caudal block, Erector spinae block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Analgesia, Epidural
Effects of an Educational Tool on Knowledge and Risk Retention About Epidural Analgesia in Parturients.
The purpose of this study if to assess the basic knowledge of parturients about epidural analgesia, including an assessment of risks and benefits, but also risks associated with the procedure, and the impact of giving an…
- Trial name
- NCT05355103
- Testing
- Educational tool about epidural analgesia
- Where
- Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Urinary Tract Infections
Early or Late Foley Removal After Thoracotomy
Is the early removal of Foley catheter safe in patients undergoing general thoracic surgery with an epidural catheter in place?
- Trial name
- NCT01611519
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain, Postoperative, Anesthesia
Anaesthesiological Involvement in Postoperative Pain Treatment
This study aims to investigate the current organization and management of postoperative pain in Denmark, especially for invasive pain treatment modalities (epidural infusions, PCA and regional blocks), in a national survey…
- Conditions
- Pain, Postoperative, Anesthesia, Epidural Analgesia, Acute Pain
- Trial name
- NCT03496194
- Where
- Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Epidural Block, Oesophageal Cancer
The Hemodynamic Effect Between Two Types of Anesthesia in Esophageal Surgery
Continuous Paravertebral block (PVB) was reported to provide less episodes of hypotension than continuous thoracic epidural block (TEB).
- Conditions
- Epidural Block, Oesophageal Cancer, Oesophagectomy
- Trial name
- HEMOBLOC (NCT03185403)
- Testing
- paravertebral block, thoracic epidural block, ropivacaine
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
To Compare Efficacy of Dexmedetomidine in Bilateral Quadratus Lumborum vs Lumbar Epidural Blocks on Analgesia After Major Lower Abdominal Surgery
Clinical Efficacy and Safety of Dexmedetomidine as an Adjuvant in Quadratus Lumborum Versus Epidural Block in Postoperative Lower Abdominal Cancer Surgeries
Clinical efficacy and safety of dexmedetomidine as an adjuvant in quadratus lumborum versus epidural block in postoperative patients
- Trial name
- NCT06130670
- Testing
- nerve block
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University