Clinical trials: Anesthesia, Local
Regional Anesthesia, Pain
Nociception Index Level (NOL) Perioperative Monitoring During Regional Anesthesia
This prospective observational study was conducted to assess pain using NOL index under locoregional anesthesia for orthopedic surgery of the upper limb.
- Conditions
- Regional Anesthesia, Pain, Intraoperative Monitoring
- Trial name
- NOL and LRA (NCT06300606)
- Testing
- NOL monitoring
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- American Hospital of Paris
Anesthesia, Regional
Intra-individual Reproducibility in Nerve Block Duration
An interventional randomized controlled crossover trial, to illuminate if durations in nerve block durations are predictable within the same subject.
- Trial name
- NCT03310047
- Testing
- Infusion, Lidocaine, 0.5%, 5 mL, Infusion, Lidocaine, 0.5%, 10 mL
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Anticoagulants and Bleeding Disorders, Surgery
Residual Anti-Xa Activity After Last Treatment Dose of Enoxaparin
The main objective of this study is to determine the time interval following the last treatment dose of enoxaparin at which the amount of anti-Xa level activity is reliably less than 0.2 international unit per milliliter (IU/mL)…
- Conditions
- Anticoagulants and Bleeding Disorders, Surgery, Regional Anesthesia Morbidity
- Trial name
- NCT03296033
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Wake Forest University Health Sciences
Pain
MEOPA Versus Local Anesthesia for Analgesia During Chorionic Villus Sampling.
determine if efficiency of MEOPA anesthesia is at least equivalent to local anesthetics into the chorionic villus sampling in the first trimester of pregnancy
- Trial name
- MELIBIO (NCT02573987)
- Testing
- Oxygen/nitrous oxide equimolar mix, Lidocaine
- Where
- France
- Volunteers
- 192 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Postoperative Analgesia, Anesthesia; Functional
Comparison of Two Regional Technics In Knee Artroplasty
Purpose: This prospective, randomised, controlled, single-blind, multicentre study was designed to investigate the effects of peripheral nerve block methods (applied using unilateral spinal anaesthesia [USA] on elderly patients…
- Trial name
- CTRTIKA (NCT03021421)
- Testing
- intratechal (subarachnoidal )injection, lombar plexus and sciatic nerve injection
- Volunteers
- 60 people
- Sponsor
- Ordu University
Pilonidal Cyst and Sinus Without Abscess, Pilonidal Sinus Disease
The Effect of Local Anesthesia Techniques on Postoperative Pain After Laser Treatment of Pilonidal Sinus
"Assessment of postoperative pain with conventional and tumescent local anesthesia in the laser treatment of pilonidal sinus." The aim of this study is to: examine the possible difference in postoperative pain between two local…
- Conditions
- Pilonidal Cyst and Sinus Without Abscess, Pilonidal Sinus Disease, Pilonidal Sinus Treatment, Laser Ablation
- Trial name
- NCT07408414
- Testing
- local anesthesia using 2% lidocaine, SiLaC, Questionnaire and physical examination
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Opća županijska bolnica Požega
Healthy Volunteers
Does Perineural Dexamethasone Prolong Duration of a Nerve Block?
The purpose of this study is to investigate whether dexamethasone as an adjuvant to ropivacaine for adductor canal block increases duration of the sensory block, when controlling for a systemic effect using a paired design and…
- Trial name
- NCT02351804
- Testing
- Ropivacaine + dexamethasone
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Anterior Cruciate Ligament Reconstruction, Regional Anesthesia, Saphenous Nerve Block
Comparing Subsartorial Saphenous Nerve Blocks With and Without Dexamethasone for Anterior Cruciate Ligament Reconstruction
For patients undergoing Anterior Cruciate Ligament reconstruction surgery, the postoperative period can be a painful experience without adequate pain management.
- Trial name
- NCT01586806
- Testing
- Bupivacaine Only, Bupivacaine with 1 mg of Dexamethasone, Bupivacaine with 4 mg of Dexamethasone
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Hospital for Special Surgery, New York
Regional Anesthesia Block, Brachial Plexus Blocks
Comparison Between Ultrasound-Guided Costoclavicular and Lateral-Sagittal Infraclavicular Brachial Plexus Blocks in Adult Distal Upper Limb Surgeries
The aim of the study is to compare the onset time of the costoclavicular approach of brachial plexus block with that of the lateral-sagittal infraclavicular approach in adults distal upper limb surgeries.
- Trial name
- NCT07517809
- Testing
- Costoclavicular brachial plexus block, Lateral-sagittal infraclavicular brachial plexus block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Breast Surgery
Pectoralis Block vs Paravertebral Nerve Blocks for Breast Surgery
Following painful surgical procedures of the breast, postoperative analgesia is often provided with a nerve block called a "paravertebral" block.
- Trial name
- NCT04742309
- Testing
- Pecs-2 block (single injection), Paravertebral block (single injection)
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of California, San Diego
Healthy
The Impact of Local Anesthetic Dilution on Possible Blinding for Nerve Blocks
This study aims to determine the appropriate dosage of a placebo anesthetic to enable future placebo-controlled studies that can more accurately examine the effects of nerve blocks.
- Trial name
- NCT06668116
- Testing
- Ropivacaine 0,1%
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Regional Anesthesia Morbidity
Efficacy of SAP Block Versus ESP Block in VATS Surgery
During VATS (Video assisted thoracic surgery) small incisions are made in the patient's chest through which a camera and instruments are inserted to allow a lung operation to be performed.
- Trial name
- ESPvSAP (NCT03862612)
- Testing
- regional anaesthesia with Levobupivicaine 0.25% 30mls with two methods either erector spinae plane block or serratus anterior plane block
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- Mater Misericordiae University Hospital
Pediatric Cancer
Continuous Erector Spinae Block for Post Analgesia in Pediatric Patients
The aim of this study is to evaluate the analgesic efficacy of erector spinae plane block in pediatric cancer patients undergoing open nephrectomy
- Trial name
- NCT04613830
- Testing
- Bupivacaine Hydrochloride, Tramadol hydrochloride
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Achilles Tendinopathy
Achilles Tendinopathy Treated With Training and Injections
The purpose of this study is to compare in a randomized double blinded controlled trial the effect of heavy slow resistance exercises combined with ultrasound guided injections with local anesthetic with or without…
- Trial name
- NCT02580630
- Testing
- Reduction in running and jumping, Training, Ultrasound guided injection with Glucocorticosteroid
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Bispebjerg Hospital
Ankle Fractures
WALANT and Spinal Anesthesia Comparison of Clinical Result in Ankle Fractures
The application of the WALANT technique for foot and ankle surgery (joint fusion, implant removal and tendon repair, etc.) is limited. In our study, using the WALANT technique for ARIF in ankle fractures.
- Trial name
- NCT06077344
- Testing
- WALANT in Ankle Fractures (Wide-Awake Local) Anesthesia No Tourniquet) and Applied Under Spinal Anesthesia Comparison of Clinical Results of Surgical Treatment;ANT Procedure comparation, Applied Under Spinal Anesthesia of Clinical Results of Surgical Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Delirium
Rate of Postoperative Delirium and Postoperative Cognitive Dysfunction After Spinal Anesthesia
The aim of this investigation is to compare the standard of general anesthesia used in these patients with these short-acting local anesthetics (Chloroprocain (Ampres®) and Prilocain (Takipril®)) for spinal anesthesia as well as…
- Trial name
- NCT03715244
- Testing
- Spinal anesthesia with short-acting local anesthetics, General anesthesia (current standard)
- Where
- Germany
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Choroid Disease, Carotid Stenosis
Ophthalmologic Outcomes in Patients With Carotid Artery Stenosis
The retinal vessels have been shown to reflect vascular changes inherent to systemic pathologies, even when no ocular disease is identified.
- Conditions
- Choroid Disease, Carotid Stenosis, Carotid Atherosclerosis, Retinal Disease
- Trial name
- NCT05623293
- Testing
- eye - Optcial coherence tomography
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Universidade do Porto
Ankylosing Spondylitis (AS), Back Pain
Efficacy of the Erector Spinae Plane Block for Persistent Back Pain in Patients With Ankylosing Spondylitis
Despite adequate control of disease activity with standard medical therapies, there remains an ongoing need for complementary and interventional approaches for the management of persistent back pain in patients with ankylosing…
- Conditions
- Ankylosing Spondylitis (AS), Back Pain, ESPB, Regional Anesthesia
- Trial name
- NCT07633730
- Testing
- Erector spinae plane block(ESBP)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Marmara University
Soft Tissue Injuries
Effectiveness of Phentolamine Mesylate as a Reversing Agent for Local Anesthesia in Children
Local anaesthesia is considered one of the most alarming and non-comfortable dental procedures for children. This goes back to the persisting effect of the local anaesthesia after finishing dental procedures.
- Trial name
- NCT05448807
- Testing
- OraVerse
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Inguinal Hernias
Local Anaesthetic Following Hernia Repair
Inguinal hernia repair is a common surgical procedure. The major current debates revolve around laparoscopic hernia repair. The most recent Cochrane review concluded that laparoscopic inguinal hernia repair was associated with…
- Trial name
- NCT00471692
- Testing
- Ropivicaine
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Royal Hobart Hospital