Clinical trials: Anesthesia, Recovery
Laparoscopy, Anesthesia Recovery Period
Deep Neuromuscular Block for Laparoscopic Surgery
Trial summary: deep neuromuscular block is proposed as a technique to improve operative conditions for laparoscopy. Early clinical data would suggest that there may also be patient benefits beyond the operative period related to…
- Trial name
- DEEPBLOCK (NCT03034577)
- Testing
- Sugammadex, Neostigmine
- Where
- 4 sites in Australia
- Volunteers
- 350 people
- Sponsor
- University of Melbourne
Residual Neuromuscular Blockade
Thumb vs Great Toe Recovery
Researches are comparing the accuracy of measuring muscle relaxation in the thumb versus the great toe.
- Trial name
- NCT04312256
- Testing
- TetraGraph
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Mayo Clinic
Postoperative Pain, Adverse Effects
Continuous Interscalene Block Results in Superior Recovery Throughout the First Postoperative Week
The investigators undertook this prospective, randomized trial to compare the recovery profile throughout the first postoperative week in patients receiving continuous (CISB) interscalene brachial plexus block, single injection…
- Trial name
- NCT01881776
- Testing
- ISB
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Delayed Emergence From Anesthesia, Postoperative Delirium
Trajectory of Recovery in the Elderly
The purpose of this study is to understand how elderly individuals regain their cognitive skills following general anesthesia. The investigators will compare an age stratified group of volunteers who will be evaluated with a…
- Conditions
- Delayed Emergence From Anesthesia, Postoperative Delirium, Postoperative Cognitive Dysfunction
- Trial name
- TORIE (NCT02275026)
- Testing
- Functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anesthesia
Optimizing Post-operative Recovery in Bariatric Patients With Obstructive Sleep Apnea Undergoing Outpatient Surgery: A Comparison of Sugammadex and Neostigmine
This study assesses the efficacy of sugammadex against neostigmine for hastening recovery from neuromuscular blockade and optimizing pulmonary function in obese patients with obstructive sleep apnea presenting for outpatient…
- Trial name
- NCT04570150
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Diego
Post-anesthesia Recovery, Orientation
Use of Ketamine vs Methohexital for Electroconvulsive Therapy (ECT) on Patient Recovery and Re-orientation Time
When undergoing ECT treatments, patient recovery time and re-orientation time may be shorter using ketamine for induction than using methohexital.
- Trial name
- NCT01567852
- Testing
- Ketamine, Methohexital
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of New Mexico
Lung Cancer
Comparison of Emergence and Oxygenation During One-lung Ventilation With Desflurane and Propofol Anesthesia
Which is more adequate general anesthetic agent, desflurane or propofol, for emergence and recovery time, and perioperative oxygenation in lung resection surgery?
- Trial name
- NCT02324283
- Testing
- desflurane, propofol
- Where
- Japan
- Volunteers
- 80 people
- Sponsor
- Juntendo University
Hypercapnia
Improved Patient Recovery After Anesthesia With Hypercapnia Hyperpnoea
The proposed study will measure the time from the end of surgery until the time patients meet the discharge criteria from the postoperative anesthesia care unit and the time from the end of surgery until the patients regained…
- Trial name
- NCT00708526
- Testing
- standard of care for phase one anesthesia care, Quick Emergence Device
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Utah
Postoperative Pain, Postoperative Nausea and Vomiting
Low Doses of Ketamine and Postoperative Quality of Recovery
There are evidences that intraoperative administration of low doses of ketamine may contribute to control the postoperative pain by acting on the N-methyl-D-aspartate (NMDA) channel, reducing the effects related to the tolerance…
- Trial name
- NCT02571153
- Testing
- Ketamine 0.4 mg/kg, Normal saline, Ketamine 0.2 mg/kg
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Gastrostomy
Transversus Abdominis Plane Block on Stress Response
This study evaluates the effect of transversus abdominis plane(TAP) block combined with general anesthesia on perioperative stress response in patients undergoing radical gastrectomy.
- Trial name
- NCT03035916
- Testing
- Transversus abdominis plane block, Epidural anesthesia, control
- Where
- China
- Volunteers
- 91 people
- Sponsor
- Jilin University
Anesthesia
EEG Studies of Sevoflurane-Induced General Anesthesia
The investigators are performing this research study to find out how and where the anesthetic drugs sevoflurane and ketamine act in the brain.
- Trial name
- NCT03503578
- Testing
- Sevoflurane, Ketamine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Intraoperative Complication, Malignant Female Reproductive System Neoplasm
Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery
This randomized clinical trial studies epidural anesthesia within an enhanced recovery pathway (ERP) in reducing pain in patients undergoing gynecologic surgery.
- Conditions
- Intraoperative Complication, Malignant Female Reproductive System Neoplasm, Pain
- Trial name
- NCT02423876
- Testing
- Epidural analgesia, Intraoperative Complication Management and Prevention, Pain Therapy
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Wisconsin, Madison
Anesthesia
EEG Studies of Ketamine General Anesthesia
We are doing this research study to find out how and where ketamine acts in the brain. Ketamine is an anesthetic (a drug or agent used to decrease or eliminate the feeling of pain by putting you in an unconscious state).
- Trial name
- NCT03553758
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Brain Activity Under Sedation
EEG Studies of Induction and Recovery From Propofol Induced General Anesthesia
The purpose of this study is to investigate how the commonly used anesthetic drug propofol works in the brain to produce loss of consciousness.
- Trial name
- NCT01543633
- Testing
- Propofol
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Neuromuscular Blockade
Incidence of Incomplete Postoperative Neuromuscular Recovery From Anesthesia (P07535)(Completed)
This is a multicenter, observational study in adult participants undergoing different types of elective surgical procedures requiring general anesthesia.
- Trial name
- INSPIRE (NCT01181349)
- Testing
- Neuromuscular Blocking Agent (NMBA)
- Volunteers
- 350 people
- Sponsor
- Merck Sharp & Dohme LLC
Postoperative Respiratory Condition
Effect of Neuromuscular Reversal With Sugammadex on Postoperative Recovery Profile
Suboptimal reversal of neuromuscular blockage after surgery is possibly related to unfavorable postoperative respiratory conditions and elevated pain levels.
- Trial name
- Neuropa (NCT02243943)
- Testing
- Sugammadex, Neostigmine
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Leiden University Medical Center
Postoperative Nausea and Vomiting, Respiratory Conditions Due to Other External Agents
A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery
The investigators will track bariatric patients who received sugammadex versus neostigmine in the post anesthesia care unit until discharge and assess their length of stay and possible nausea / vomiting / hypoxia episodes.
- Trial name
- NCT03276026
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Delayed Emergence From Anesthesia
Recovery Profile Comparison Between Remifentanil-propofol or Desflurane Anesthesia Monitored With Bispectral Index.
Bispectral monitoring anesthesia with remifentanil-desflurane has a better post-operative recovery than remifentanil-propofol.
- Trial name
- NCT02631525
- Testing
- Desflurane, Propofol
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Postoperative Pain
A Comparison of Intra-op Ketamine vs Placebo in Patients Having Spinal Fusion
Postoperative pain is severe after major spine surgery. Opioids such as morphine and hydromorphone are routinely used for postoperative pain control.
- Trial name
- NCT02424591
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- NYU Langone Health
Recovery Following Cholecystectomy
Multi-dose Acetaminophen for Patients Undergoing General Anesthesia
Study Objective The aim of the proposed study is to examine the effect of Q4 hour multidose IV acetaminophen on patients' readiness for discharge.
- Trial name
- NCT02832687
- Testing
- Acetaminophen, normal saline
- Where
- 3 sites in United States
- Volunteers
- 88 people
- Sponsor
- Rutgers, The State University of New Jersey