Clinical trials: Anesthesia, Recovery
Pain
The Effect of Intraoperative Esmolol to Improve Postoperative Quality of Recovery and Pain After Ambulatory Surgery
Seventy percent of surgeries performed in the United States are done in an outpatient setting.Pain Control after ambulatory surgery is very challenging because patients do not have access to fast and potent intravenous…
- Trial name
- NCT01782898
- Testing
- Esmolol administered at a rate of 0.5 mg/kg followed by an infusion of 5-15 mcg/kg/min
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Northwestern University
Surgery, Anesthesia
Propofol Versus Sevoflurane Recovery After Gynecological Surgery
80% of 25 million American who undergo surgery describe moderate to severe pain. The use of multimodal analgesic techniques can attenuate patient's postoperative pain and several different medication have been found to be…
- Trial name
- NCT01755234
- Testing
- Sevoflurane, Propofol
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Northwestern University
Adverse Effect of Other General Anesthetics
Effect of Flumazenil on Recovery From General Anesthesia With Isoflurane
Background and objectives: The inhalational anesthetic isoflurane is widely used in general anesthetics. Its mechanism of action involves interaction with the receptor of gamma-amino butyric acid (GABA), which is also the binding…
- Trial name
- NCT02157428
- Testing
- Flumazenil, saline
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Post-operative Pain, Post-cardiac Surgery
Paravertebral Block for Improvement of Quality of Recovery Following Cardiac Surgery
This study aims to evaluate the efficacy of bilateral, paravertebral blockade (intervention) against sham blocks (control) placed prior to sternotomy in improving quality of recovery following cardiac surgery.
- Conditions
- Post-operative Pain, Post-cardiac Surgery, Cardiac Disease
- Trial name
- NCT06008821
- Testing
- Bilateral paravertebral block with 0.25% ropivicaine with 1:400,000 epinephrine
- Where
- Canada
- Volunteers
- 224 people
- Sponsor
- University of British Columbia
Patient Reported Outcome Measures, Quality of Recovery
Translation and Validation of the Turkish Version of the ObsQoR-11 Questionnaire
Ciechanowicz et al. developed and validated a postpartum recovery score for women with a caesarean section: the ObsQoR-11. The psychometric validation of the ObsQoR-11 confirms its reliability, its response to change, its…
- Conditions
- Patient Reported Outcome Measures, Quality of Recovery, Cesarean Section, General Anesthesia
- Trial name
- ObsQoR-11T (NCT04744311)
- Testing
- ObsQoR-11T Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Delayed Recovery From Anaesthesia
Measurement of Psychomotor Recovery After Anesthesia Using 4CRT
The aim of the investigation is to validate the SmartPhone-based 4-Reaction Choice Time Test (4CRT) as a measure for recovery of the psychomotor function in patients after general anesthesia.
- Trial name
- 4CRT (NCT02232139)
- Testing
- Midazolam
- Where
- Germany
- Volunteers
- 124 people
- Sponsor
- University Medicine Greifswald
Rocuronium, Muscle Weakness
General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery
Neuromuscular blocking agents are often used during general anesthesia. Also, general anesthesia may be performed without use of neuromuscular blocking agents.
- Conditions
- Rocuronium, Muscle Weakness, General Anaesthesia
- Trial name
- NCT04760912
- Testing
- Rocuronium, General anesthesia for surgery
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
Regional Anesthesia Morbidity, Pain, Postoperative
Efficacy of Ultrasound Guided ESP Vs Video-assisted PVB Catheter Placement in Minimally Invasive Thoracic Surgery
Minimally Invasive Thoracic Surgery (MITS) is a surgical method used to perform lung surgery through small incisions between the ribs and includes both Video-Assisted Thoracic Surgery (VATS) and Robotic assisted Thoracic Surgery…
- Conditions
- Regional Anesthesia Morbidity, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04729712
- Testing
- Anaesthesiologist-administered ultrasound guided Erector Spinae block with catheter insertion, Surgeon-administered video-assisted Paravertebral block with catheter insertion
- Where
- 2 sites in Ireland
- Volunteers
- 80 people
- Sponsor
- Mater Misericordiae University Hospital
Rhinoplasty, Depth of Anesthesia
Processed EEG Monitoring During Controlled Hypotension in Patients Undergoing Rhinoplasty
This prospective observational study evaluates intraoperative processed electroencephalography parameters in adult patients undergoing elective rhinoplasty under total intravenous anesthesia with controlled hypotension.
- Conditions
- Rhinoplasty, Depth of Anesthesia, Surgical Bleeding, Postoperative Recovery
- Trial name
- NCT07671781
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Gazi University
Anesthesia, Regional, Anesthesia and Analgesia
Difference in Occurrence of Rebound Pain in Patients Undergoing Surgery Under Popliteal Block or Ankle Block
This is a monocentric, comparative prospective randomized controlled trial. Patients will be randomised into 2 groups and will receive either a sciatic popliteal nerve block or an ankle block (single dose locoregional block…
- Trial name
- CBFR (NCT05734469)
- Testing
- Forefoot bone surgery
- Volunteers
- 90 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Anesthesia Recovery
"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"
Prospective Randomized non inferiority Trial involving adult patients undergoing elective surgery under general anesthesia.56 Patients will be enrolled in 2 groups : full dose sugammadex vs half dose sugammadex for reversal of…
- Trial name
- NCT02375217
- Testing
- Sugammadex, Neostigmine, glycopyrrolate
- Where
- Lebanon
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Pain, Postoperative, Nausea and Vomiting, Postoperative
QUALITY OF RECOVERY AFTER INTRAOPERATIVE MORPHINE OR METHADONE
Introduction. Despite the advantages associated with the use of remifentanil during total intravenous anesthesia (TIVA), it has been observed a frequent difficulty in the control of postoperative pain due to the risk of…
- Trial name
- NCT03045133
- Testing
- Methadone, Morphine
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Cervical Incompetence in Pregnancy as Antepartum Condition
Hyperbaric Prilocaine Compared With Hyperbaric Bupivacaine in Cervical Cerclage?
Patients that have a "cervical stitch" (cervical cerclage) require an anaesthetic. The most common choice is a spinal block. This is an injection in the back that makes the lower half of the body become temporarily numb and weak.
- Trial name
- PRILOCC (NCT04394533)
- Testing
- Prilocaine (Hyperbaric 2%), Bupivacaine (Hyperbaric 0.5%)
- Where
- United Kingdom
- Volunteers
- 129 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Anesthesia, Psychomotor Status
Driving Skills Recovery Following Procedural Sedation for Gastrointestinal Endoscopy
This is a prospective cohort study that will analyze psychomotoric recovery using a commercially available driving simulator following sedation for endoscopic procedures in subjects undergoing elective outpatient endoscopic…
- Trial name
- NCT04350424
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Postoperative Recovery, General Anaesthesia
Intercultural Adaptation and Validation of the Ukrainian Quality of Recovery-15 Questionnaire
The Quality of Recovery 15-questionnaire (QoR-15) is used to assess postoperative quality of recovery after surgery and anesthesia from the patient's perspective.
- Conditions
- Postoperative Recovery, General Anaesthesia, Validation, Questionnaire
- Trial name
- NCT07510360
- Testing
- Quality of Recovery-15 questionnaire, Ukrainian version
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rostyslav Voloshchuk
Postoperative Quality of Recovery
Validation of the German Quality of Recovery-15 Questionnaire
The Quality of Recovery 15-questionnaire (QoR-15) is used to assess postoperative quality of recovery after surgery and anesthesia from the patient's perspective.
- Trial name
- NCT04528524
- Testing
- Questionnaire
- Where
- Germany
- Volunteers
- 186 people
- Sponsor
- Marlene Fischer
Anesthesia
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block…
- Trial name
- EKAT-TeleTPS (NCT03747146)
- Testing
- Continuous Adductor Canal Catheter (ACC)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Postoperative Pain, Spinal Fusion Surgery
TLIP Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery
This prospective randomized controlled study aims to compare the effects of ultrasound-guided thoracolumbar interfascial plane (TLIP) block versus retrolaminar block on postoperative quality of recovery in patients undergoing…
- Conditions
- Postoperative Pain, Spinal Fusion Surgery, Degenerative Lumbar Spine Diseases
- Trial name
- TLIP-RLB-QoR (NCT07609212)
- Testing
- Thoracolumbar interfascial plane block, Retrolaminar block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Emergence Delirium, Anesthesia
Study on the Correlation Between Plasma Orexin Levels During the Recovery Period and Emergence Delirium in Elderly Patients
To explore the relationship between plasma orexin levels during the recovery period of elderly patients undergoing general anesthesia and the occurrence of emergence delirium, and to evaluate its sensitivity and specificity as an…
- Trial name
- NCT07726875
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Ruijin Hospital
Respiratory Aspiration, Hyperglycemia
Maltodextrin Versus Sugar Water Carbohydrate Loading and Gastric Volume in Geriatric Lower Limb Orthopedic Surgery
Before surgery, patients are asked to fast so the stomach is empty and stomach contents cannot enter the lungs during anesthesia. Long fasting is uncomfortable and can raise blood sugar and stress responses in older adults.
- Conditions
- Respiratory Aspiration, Hyperglycemia, Inflammation
- Trial name
- CHO-GERIGAS (NCT07872683)
- Testing
- Maltodextrin carbohydrate drink, Sugar water
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Udayana University