Clinical trials: Anesthesia, Recovery
Hip Osteoarthritis, Total Hip Arthroplasty (THA)
QIPB vs SI-FICB for Postoperative Analgesia After Total Hip Arthroplasty
Total hip arthroplasty (THA) causes moderate-to-severe postoperative pain. The PROSPECT guideline recommends the supra-inguinal fascia iliaca compartment block (SI-FICB) for THA, whereas evidence for newer…
- Conditions
- Hip Osteoarthritis, Total Hip Arthroplasty (THA), Postoperative Pain, Acute Pain
- Trial name
- NCT07683663
- Testing
- Supra-Inguinal Fascia Iliaca Compartment Block, Quadro-Iliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Dokuz Eylul University
Adenotonsillectomy, Preoperative Anxiety
Timing Of Midazolam İn Children Undergoing Adenotonsillectomy: Effects On Stress, Cortisol, And Recovery
This study is a prospective, randomized, controlled clinical trial designed to evaluate the optimal timing of midazolam administration in children undergoing adenotonsillectomy.
- Conditions
- Adenotonsillectomy, Preoperative Anxiety, Surgical Stress Response, Postoperative Pain
- Trial name
- Timing-Midazol (NCT07622641)
- Testing
- Midazolam (Oral), Midazolam (Intravenous)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Erzurum City Hospital
Agitated; State, Acute Reaction to Stress
Does Low Flow Anesthesia Reduce Postanaesthetic Emergence Agitation?
In this study, the investigators aimed to compare postanesthetic agitation in patients undergoing laparotomic gynecological surgery under general anesthesia using sevoflurane at a fresh gas flow rate of 2 L / min with fresh gas…
- Trial name
- NCT03862391
- Testing
- Analgesics, Antiemetics
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Postoperative Pain
Effects of Regional Anesthesia Following Mastectomy
Patients of breast surgery dated between April 2016 and March 2021 will be scanned in three groups; solely induced general anesthesia, general anesthesia induced with Erector Spinae Plane Block, and general anesthesia induced…
- Trial name
- NCT05276440
- Volunteers
- 182 people
- Sponsor
- Koc University Hospital
Postpartum Recovery, Mother-infant Bonding
Labor Epidural Analgesia and Mother-Infant Bonding After Vaginal Delivery
This prospective observational cohort study aims to evaluate the association between postpartum recovery quality and mother-infant bonding in women undergoing vaginal delivery.
- Conditions
- Postpartum Recovery, Mother-infant Bonding, Labor Pain
- Trial name
- NCT07582289
- Testing
- Labor Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ataturk University
Radical Prostatectomy, Postoperative Pain
Postoperative Pain, Recovery and Discharge Following Robot-assisted Laparoscopic Prostatectomy
Prostate cancer is the commonest cancer form in men in Northern Europe. Management of the cancer often includes surgical removal of the primary tumor.
- Trial name
- RAPID (NCT03639389)
- Testing
- Bupivacaine, Analgesics
- Where
- 2 sites in Sweden
- Volunteers
- 211 people
- Sponsor
- Karolinska Institutet
Pulmonary Nodules, Early Stage Lung Cancer (I and II)
Tubeless Strategy for Enhanced Recovery After Sublobar Resection
This is a prospective, randomized controlled clinical trial conducted at a single center. The study aims to evaluate whether a "tubeless" strategy can enhance recovery for patients undergoing minimally invasive thoracoscopic…
- Conditions
- Pulmonary Nodules, Early Stage Lung Cancer (I and II), Thoracoscopic Surgery, Sublobar Resection
- Trial name
- NCT07409129
- Testing
- Laryngeal Mask Airway, Thoracic Paravertebral Block with Local Anesthetic, Non-intubated Anesthesia
- Where
- China
- Volunteers
- 138 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Quality of Life, Pain, Postoperative
Quality of Recovery After General or Spinal Anesthesia for Inguinal Hernia Repair
Different anesthetic techniques have been proposed for carrying out Inguinal hernia repair, including local anesthesia, regional and general.
- Conditions
- Quality of Life, Pain, Postoperative, Personal Satisfaction, Postoperative Complication
- Trial name
- NCT02696122
- Testing
- Local Group, Spinal anesthesia
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Patients Undergoing Spine Surgery
Comparison of Postoperative QoR-15 Scores Between Propofol and Remimazolam
Remimazolam is a ultra-short-acting benzodiazepine, and unlike conventional benzodiazepine drugs, it is rapidly metabolized in plasma and not accumulates in the body for long periods of infusion or even with high dose…
- Trial name
- NCT04994704
- Testing
- Propfol group, Remimazolam group
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Opioid-Free Anesthesia, Laparoscopic Sleeve Gastrectomy
Effect of Opioid-free Analgesia and Anesthesia on the Quality of Postoperative Recovery and Nausea Vomit in Patients Receiving Laparoscopic Sleeve Gastrectomy
The purpose of the intraoperative use of opioids is to reduce the amount of sedative medication and to ensure effective analgesia.
- Conditions
- Opioid-Free Anesthesia, Laparoscopic Sleeve Gastrectomy, Postoperative Vomiting, Postoperative Recovery
- Trial name
- NCT06305221
- Testing
- Opioid-free Analgesics (esketamine, dexmedetomidine), Opioid Anesthetics (sufentanil and remifentanil)
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Beijing Friendship Hospital
Anesthesia; Sexual, Analgesia
The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section
The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section…
- Trial name
- NCT05758233
- Testing
- Patients undergoing transversalis fascia plane block, Patients undergoing transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Enhanced Recovery After Surgery, Mortality
Impact of Anesthesia-related Enhanced Recovery After Surgery Components on Mortality After Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD), one of the most complex and invasive abdominal surgeries, is associated with long length of stay (LOS) and high morbidity and mortality rates.
- Trial name
- NCT06256133
- Testing
- Enhanced Recovery After Surgery protocol
- Where
- South Korea
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Breast Diseases
MAC vs TIVA Ambulatory Breast Augmentation
hypothesis: the combination of LA with remifentanil and ketofol [monitored anesthesia care (MAC)] for ambulatory breast augmentation may result in results in better QoR on day of surgery as compared with total i.v.
- Trial name
- NCT03764267
- Testing
- Remifentanil, general anesthetic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cholecystectomy, Laparoscopic, Noise
The Effect of Noise Control During Anesthesia Induction in Laparoscopic Cholecystectomy Surgery
This study aims to determine the effects of active and passive noise control method and headphone usage and noise level during anesthesia induction in laparoscopic cholecystectomy surgery on hemodynamic parameters, pain, nausea…
- Conditions
- Cholecystectomy, Laparoscopic, Noise, Anesthesia Induction
- Trial name
- Anesth-noise (NCT06666686)
- Testing
- Active noise control headphone, Passive noise control headphone
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Fracture of Ankle
Analgesic Benefits of Perineural Versus Intravenous Dexamethasone in Patients Receiving Sciatic Nerve Block
Patients scheduled to have foot and ankle surgery will typically receive a single shot sciatic nerve block to serve as the primary anesthetic and as part of a multi-modal post-operative analgesic plan.
- Trial name
- NCT01616173
- Testing
- Dexamethasone, Saline
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Postoperative Pain
Comparison of Interpectoral+Serratus Anterior Block With Erector Spinae Block in Minimally Invasive Cardiac Surgery
Adequate pain management after minimally invasive cardiac surgery is essential for early ambulation and patient satisfaction. However, an incision similar to thoracotomy surgery is made by entering between the ribs, and a…
- Trial name
- NCT05743231
- Testing
- interpectoral area block + serratus anterior area block group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Intratracheal, Dexmedetomidine
Effect of Intratracheal Dexmedetomidine Administration on Recovery From General Anesthesia in Pediatrics Undergoing Lower Abdominal Surgery:
The incidence of intratracheal tube-induced laryngeal irritation, including coughing, bucking, and cardiovascular stimulation, on emergence from general anesthesia has been reported to occur in 38% and 96% of cases.
- Trial name
- NCT04385602
- Testing
- Intratracheal dexmedetomidine, Saline Solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Analgesia
Effect of Intrathecal Morphine on Urinary Bladder Function and Recovery in Patients Having a Cesarean Delivery
The enhanced recovery anesthesia concept has been widely adopted, including cesarean delivery. Modern obstetrical anesthesia aims to offer an experience to a patient undergoing a cesarean delivery similar to normal vaginal…
- Trial name
- NCT05042817
- Testing
- 100 mcg morphine, 0.9% NaCl, 50 mg prilocaine + 2.5 mcg sufentanil
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University of Liege
Anesthesia Recovery
"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"
Prospective Randomized non inferiority Trial involving adult patients undergoing elective surgery under general anesthesia.56 Patients will be enrolled in 2 groups : full dose sugammadex vs half dose sugammadex for reversal of…
- Trial name
- NCT02375217
- Testing
- Sugammadex, Neostigmine, glycopyrrolate
- Where
- Lebanon
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Surgery, Anesthesia
Intravenous Sedation Versus General Anesthesia in Patients Undergoing Minor Gynecologic Surgery
The use of deep sedation may improve the quality of recovery of patients undergoing minor gynecologic procedures. These patients may also have shorter hospital stays and potentially lower healthcare costs.
- Conditions
- Surgery, Anesthesia, Pain
- Trial name
- NCT01890707
- Testing
- General Anesthesia, Deep Sedation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Northwestern University