Clinical trials: Anesthesia
Aortic Aneurysm, Thoracic
Impact of Anesthesia on the Dimension of the Ascending Aorta
The aim of this study is to evaluate the accuracy and reliability of intra-operative TEE after the induction of anesthesia when assessing proximal thoracic aorta diameters in a cohort of aortic aneurysm patients.
- Trial name
- NCT03431870
- Testing
- Trans-esophageal echocardiography
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Cardiac Output, Hypotension
Cardiac Output Changes During Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Cesarean Section
Spinal block leads to the reduction of systemic vascular resistance (SVR) which may effect the cardiac output. Ngan Kee et al. has showed that spina block with 0.5% hyperbaric bupivacaine for Cesarean section combined with…
- Conditions
- Cardiac Output, Hypotension, Anesthesia, Spinal
- Trial name
- NCT02737813
- Testing
- Isobaric marcaine, Hyperbaric marcaine
- Where
- Thailand
- Volunteers
- 168 people
- Sponsor
- Mahidol University
Anesthesia Intubation Complication
Tracheal Palpation of Sliding Cuff to Assess Endotracheal Tube Location
Correct endotracheal tube (ETT) placement is important. Proper ETT position is achieved when the distal tip is in mid-trachea with the head in neutral alignment.
- Trial name
- NCT02502461
- Testing
- cuff palpation
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Saskatchewan
Pregnancy Related, Cesarean Section Complications
Predictive Hemodynamic Monitoring During Elective Cesarean Section
Single shot spinal anesthesia (SA) is the most commonly used technique for Caesarean section (CS) . SA is associated with maternal hypotension (Post Spinal Hypotension - PSH) often accompanied by nausea, vomiting, bradycardia and…
- Conditions
- Pregnancy Related, Cesarean Section Complications, Hypotension on Induction, Anesthesia Complication
- Trial name
- PREDICTION (NCT06729827)
- Testing
- Hypotension prediction Index - HPI
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Anesthesia
The TI.VA Algorithm: A First-in-Humans Test.
The TI.VA algorithm is a new method to titrate the anesthetic drug concentrations whenever the planned level of anesthesia results to be not appropriate to blunt the patient's reaction to surgical stimulation.
- Trial name
- TIVAly (NCT05199883)
- Testing
- TI.VA algorithm: decision support system
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Anesthesia, Local
Quadratus Lumborum Block (Transmuscular Approach) VS. TransversusAbdominus Plane Block(Unilateral Posterior Approach) for Perioperative Analgesia in Patients Undergoing Flank Incision Surgeries.
Severe perioperative pain experienced after surgical procedures performed by flank incision is mainly related to incision of many muscles.
- Trial name
- NCT03744923
- Testing
- transmuscular QL block, Transversus Abdominus Plane block
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Anesthesia, Trachea
Simplification and Implementation of Awake Fibreoptic Orotracheal Intubation
Awake fibreoptic intubation (AFOI) is a classic and standard method for some special patients which is also difficult for anesthesiologists to learn and master. The procedure is sometimes hard and often takes about 20-30 min.
- Conditions
- Anesthesia, Trachea, Intubation
- Trial name
- NCT03343496
- Testing
- Awake fiberoptic intubation (AFOI)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Fudan University
Surgery
Evaluating Outcomes in Cardiac Surgery Patients Who Receive Sugammadex vs. Placebo
This is a prospective randomized blinded controlled trial that will enroll 175 subjects undergoing cardiopulmonary bypass at NorthShore University HealthSystem.
- Trial name
- NCT05801679
- Testing
- Sugammadex
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Endeavor Health
Analysis of Anaesthesia Depth
Prediction of Propofol Effect Compartment Concentrations
The goal of this observational study is to learn about the prediction of the effect of Propofol by means of EEGs. The main questions it aims to answer are: Develop models that can reliably predict the effect of Propofol Select…
- Trial name
- Propo2022 (NCT05940142)
- Where
- Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karl Landsteiner University of Health Sciences
Cesarean Section Complications, Hemodynamic Instability
Norepinephrine in Caesarian Section
Postspinal hypotension is a frequent maternal complication in caesarian delivery under neuraxial anesthesia which is most commonly treated with the administration of phenylephrine infusion.
- Conditions
- Cesarean Section Complications, Hemodynamic Instability, Foetal Stress
- Trial name
- NCT05264870
- Testing
- Norepinephrine
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Arthroscopic Knee Surgery, Ropivacaine
The Optimal Dosage of Ropivacaine for Arthroscopic Knee Surgery
Fast-track Surgery (FTS ) refers to the application of various proven effective methods in perioperative period to reduce stress and complications and accelerate the recovery of patients.Nowadays, FTS has been successfully…
- Conditions
- Arthroscopic Knee Surgery, Ropivacaine, Combined Spinal Epidurai Anesthesia, ED50
- Trial name
- NCT04759742
- Testing
- ropivacaine
- Where
- China
- Volunteers
- 115 people
- Sponsor
- Yanchao Yang
Dexmedetomidine Analgesia, Knee Surgery
Intravenous Regional Analgesia of Dexmedetomidine
Dexmedetomidine is a highly selective α₂-adrenergic receptor agonist that exerts its effects by inhibiting the release of norepinephrine at presynaptic nerve terminals, leading to reduced sympathetic activity; This mechanism…
- Trial name
- Dexmedetomidin (NCT07131579)
- Testing
- Normal Saline, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Anesthesia, Surgery--Complications
Intraoperative Protective Ventilation for Obese Patients Undergoing Gynaecological Laparoscopic Surgery
Background. The use of a comprehensive strategy providing low tidal volumes, peep and recruiting maneuvers in patients undergoing open abdominal surgery improves postoperative respiratory function and clinical outcome.
- Trial name
- Inprove4large (NCT03157479)
- Testing
- Intravenous anesthetic, Crystalloid Solutions, Esophageal pressure measurement
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Catholic University of the Sacred Heart
Parkinson's Disease
Sub-thalamic Nucleus Stimulation in Parkinson Disease
Deep brain stimulation (DBS) is an established procedure for the symptomatic treatment of Parkinson's disease. This procedure performed in two steps using electrophysiology.
- Trial name
- PARKEO (NCT01817088)
- Testing
- New targeting procedure without electrophysiology, Classical neurosurgical procedure
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bordeaux
Endotracheal Intubation
Comparison of Two Type of Laryngeal Mask : I-Gel & LMA ProSeal
The i-gel is a new supra glottic airway device with a non inflatable cuff and an oesophageal vent. The aim of this study is to compare this device to the LMA ProSeal. The study is approved by the institutional ethic committee.
- Trial name
- I-Gel (NCT00624403)
- Testing
- Laryngeal mask insertion (LMA ProSeal), Laryngeal mask insertion (I-Gel)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Bordeaux
Dental Anesthesia
MRI and Local Anesthesia
The purpose of this research is to investigate the utility of using dental-dedicated MRI as a measurement tool to observe and evaluate the administration of local anesthesia in dental patients.
- Trial name
- MRI and LA (NCT07602686)
- Testing
- ddMRI
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Minnesota
Morbid Obesity
The Ultrasound Guided Versus Land-mark Location Method for Performing Spinal Anesthesia in Obese Parturients
This study will be investigated whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the lateral position in morbidly obese pregnant women with BMI ≥ 40 who…
- Trial name
- NCT05342922
- Testing
- Ultrasound group, Landmark group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Spinal Anaesthesia, Herniorrhaphy
Assessment of the Impact of Two Dexmedetomidine Dosages Added with Bupivacaine in Ultrasound-Guided Transversus Abdominis Plane Block for Postoperative Analgesia Following Inguinal Hernia Repair
The principal outcome assessed was the duration until the initial request for analgesia post-surgery. The secondary outcomes encompassed the total quantity of analgesics administered (ketorolac, paracetamol, and morphine) within…
- Conditions
- Spinal Anaesthesia, Herniorrhaphy, Transversus Abdominis Plane Block
- Trial name
- NCT06703229
- Testing
- The Transversus Abdominis Plane (TAP) block, The transverse abdominis plane (TAP) block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Helwan University
Anaesthesia, Anesthesia Depth Monitoring
Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients
Perioperative assessment of adequate depth of anesthesia and analgesia is currently a recommended part of routine anesthesia practice for all surgical procedures.
- Trial name
- ANIGAPP (NCT07245654)
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Regional Anesthesia Morbidity
Safety of Regional Anesthesia in Ukraine: the Survey
The common using of ultrasound navigation makes an opportunity to develop the regional anesthesia. Regional anesthesia reduces the length of stay in the hospital, reduces the intensity of perioperative pain and decrease opioid…
- Trial name
- NCT05478629
- Testing
- Survey
- Where
- Ukraine
- Volunteers
- 182 people
- Sponsor
- Bogomolets National Medical University