Clinical trials: Anesthesia Complication
Pain, Postoperative
Regional Anesthesia for Head and Neck Reconstruction
By utilizing regional anesthesia blocks at the surgery tissue donor sites, it can potentially reduce post-operative pain while also reducing the use of opioids.
- Trial name
- NCT04304716
- Testing
- Regional Anesthesia
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Perioperative Inflammatory Response, Postoperative Pain
Suprazygomatic Maxillary Nerve Block Effect on Systemic Inflammatory Response in Cleft Palate Surgeries
the aim is to determine the value of adding bilateral supra zygomatic maxillary nerve block to general anesthesia in attenuating the systemic inflammatory response in paediatrics.
- Trial name
- NCT05495750
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alaa Mohamed Abdel Salam Ibrahim Soliman
Sore-throat, Dysphonia
No Post Intubation Laryngeal Symptoms
The purpose of the study is to test a novel endotracheal tube support device that reduces pressure of the tube on the voice box for prevention of post intubation laryngeal symptoms including sore throat, change in voice and…
- Conditions
- Sore-throat, Dysphonia, Dysphagia, Intubation Complication
- Trial name
- No-PILS (NCT05383417)
- Testing
- EndoClip
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Cesarean Section Complications
Effect of Three Weight-adjusted Vasopressors for Elective Cesarean Delivery
This study compared the effects of prophylactic infusion of metaraminol, phenylephrine and norepinephrine adjusted according to body weight on fetal acid-base balance and maternal hemodynamics.
- Trial name
- NCT04991662
- Testing
- metaraminol, Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Neuromuscular Block, Residual, Pain
Methylprednisolone vs Dexamethasone: Effects on Sugammadex Reversal, Pain, and Nausea in Adults
This randomized controlled trial aims to compare the effects of intravenous methylprednisolone and dexamethasone on the reversal time of rocuronium by sugammadex in adult patients undergoing elective septoplasty or rhinoplasty.
- Conditions
- Neuromuscular Block, Residual, Pain, Postoperative Nausea
- Trial name
- NCT07187037
- Testing
- Methylprednisolone (MP), Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Postoperative Nausea and Vomiting
Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections
Patients who present for scheduled (non-emergent) cesarean section will be given either intravenous dexamethasone or placebo prior to receiving a duramorph containing spinal anesthetic.
- Trial name
- NCT01734161
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pain, Acute, Anesthesia, Local
Intracervical Anesthesia and Pain Associated With Intrauterine Contraceptive Insertion
The primary aim of our study is to evaluate the effect of intracervical anesthesia on pain scores immediately following levonorgestrel-releasing intrauterine system (LNG-IUS) insertion in nulligravida women.
- Conditions
- Pain, Acute, Anesthesia, Local, IUD Insertion Complication
- Trial name
- NCT03111342
- Testing
- Anesthesia, Dry-needling
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Lower Extremity Problem, Gynecologic Disease
Comparison of the Effect of Remimazolam and Propofol on Perioperative Hypothermia Under Spinal Anesthesia
After dividing the patients into two groups, sedation is performed with propofol and remimazolam, respectively, after spinal anesthesia. Compare the patient's body temperature change after surgery.
- Conditions
- Lower Extremity Problem, Gynecologic Disease, Urinary Tract Disease
- Trial name
- NCT05574257
- Testing
- Propofol, Remimazolam
- Where
- South Korea
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Intubation; Difficult or Failed, Postoperative Pain
The Comparison of Direct Macintosh Laryngoscopy and HugeMed Video Laryngoscope for Nasotracheal Intubation in Children
Forty-four patients aged 4-10 years who applied to Aydın Adnan Menderes University Faculty of Dentistry for dental treatment under general anesthesia will be selected and divided into 2 groups by simple randomization.
- Trial name
- NCT05121597
- Testing
- HugeMed Videolaryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Nerve Block, Anesthesia, Local
Cutaneous Anesthesia of the Lateral Femoral Cutaneous Nerve
The purpose of this study is to investigate and describe the anatomical differences in distribution of the blocked area following a perineural LFCN (Lateral Femoris Cutaneous Nerve) block with either 8 ml or 16 ml of Ropivacaine…
- Conditions
- Nerve Block, Anesthesia, Local, Pain, Postoperative, Anatomical Distribution
- Trial name
- NCT03138668
- Testing
- Ropivacaine Injection
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Post Operative Pain, Acute
A Comparative Study Between Ultrasound Guided Thoracic Paravertebral Block VS Serrartus Anterior Muscle Block in VATS as Regard Their Effectiveness in Post-operative Analgesia
A comparative study between ultrasound guided thoracic paravertebral block VS ultrasound guided serrartus anterior muscle block in video-assisted thoracoscopic surgeries as regard their effectiveness in post-operative analgesia
- Trial name
- NCT05971368
- Testing
- thoracic paravertebal block, serratus anterior muscle block
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Postoperative
The Efface of Ketamine vs. Lidocaine in the Management of Pain After Laparoscopic Cholecystectomy
This prospective interventional study conducted at Liaquat National Hospital and Medical College compared the analgesic efficacy of ketamine and lidocaine in managing postoperative pain after laparoscopic cholecystectomy.
- Trial name
- NCT07248384
- Testing
- IV ketamine 0.5 mg/kg, IV Lidocain 60 mg/kg
- Where
- Pakistan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Frailty, Sarcopenia
Investigation of the Effects of Frailty and Sarcopenia on Postoperative Recovery and Complications in Geriatric Patients
After obtaining ethical approval, 42 patients with American Society of Anesthesiologists (ASA) scores I-III who were scheduled for surgery under general anesthesia were included in our prospective study.
- Trial name
- NCT06889714
- Testing
- ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Postoperative Cognitive Dysfunction
Implementation of a Cognitive Training Program to Reduce the Risk of Postoperative Cognitive Dysfunction
Background: The postoperative cognitive dysfunction (POCD) is a frequent complication, often underestimated and leads to a negative impact on the quality of life for patients and their families.
- Trial name
- NCT03620968
- Testing
- cognitive training
- Where
- Spain
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Centro Medico Teknon
Postoperative Pain
The Analgesic Efficacy of Wound Infiltration With Tramadol
This double-blind, randomized trial examined whether tramadol wound infiltration decreased postoperative pain following cesarean delivery under general anesthesia or reduced the need for analgesics in the immediate postoperative…
- Trial name
- NCT02518438
- Testing
- Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yeditepe University Hospital
Prosthesis Failure, Dental
Clinical Success of Anterior and Posterior Crowns in a Group of Children Treated Under General Anesthesia
This incidence study aims to evaluate the clinical success of anterior and posterior full-coverage restorations among a group of Egyptian children treated under general anesthesia.
- Trial name
- NCT06201481
- Testing
- anterior and posterior full coverage crowns
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Neostigmine
Observational Study in Bariatric Surgery
Obesity in the world represents a growing share of the general population. At hospital, the management of these patients could be problematic especially when calculating the drug dosage.
- Conditions
- Obesity, Neostigmine, Residual Neuromuscular Blockade
- Trial name
- NEOCURE (NCT04244266)
- Testing
- NO INTERVENTION, it is an observational study
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Nausea and Vomiting, Postoperative
Propofol Versus Dexmedetomidine on the Incidence of Postoperative Nausea and Vomiting
Post-operative nausea and vomiting are a leading cause of recovery room delays and low patient satisfaction. Complications such as suture line tension, wound hemorrhage and dehiscence, elevated intracranial pressure, pulmonary…
- Trial name
- NCT05875077
- Testing
- Dexmedetomidine, Propofol
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia, Pediatric
Paediatric Microcuff Pressure Study
In paediatric anaesthesia, use of cuffed endotracheal (ET) tubes is subject to much debate. The concern is the possibility of damage to tracheal mucosa by excessive pressure from the cuff.
- Conditions
- Anesthesia, Pediatric, Intubation Complication
- Trial name
- MicroCuff (NCT03240354)
- Testing
- Saline cuff, Control
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Postoperative Pain, Opioid Use
SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A
The suprazygomatic maxillary nerve (SZMN) block is a well-established, safe and effective regional technique for pain management following cleft palate procedures, however, have not been studied for patients undergoing…
- Trial name
- SZMN (NCT04797559)
- Testing
- SZMN Block
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University