Clinical trials: Anesthesia Complications
Perioperative Complication
A Pilot Study of the Effects of 4 vs 3 Hours of Preoperative Fasting in Breast-feeding Infants
In the new guideline from ESAIC breast-feeding should be encouraged until 3 hours before anesthesia. This recommendation was based mainly on gastric emptying studies in neonates with small sample sizes and single center…
- Trial name
- BMRCT (NCT05573165)
- Testing
- 3 hours of preoperative fasting for breast milk, 4 hours of preoperative fasting for breast milk
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Uppsala University Hospital
Vital Sign Monitoring, Post Operative Complications
Continuous Vital Sign Monitoring Versus Routine Spot-checks in Patients After Non-cardiac Surgery
The "COME ON, NOW!" trial is a randomized, single-center trial in patients recovering from non-cardiac surgery on normal wards investigating whether continuous vital sign monitoring - compared to routine spot-checks by nurses …
- Conditions
- Vital Sign Monitoring, Post Operative Complications, Non-cardiac Surgery, RCT
- Trial name
- COME ON NOW (NCT07385092)
- Testing
- Unblinded continuous vital sign monitoring, Blinded continuous vital sign monitoring
- Where
- Germany
- Volunteers
- 264 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Fraily, Abdominal Surgery
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
This is a bicentric, prospective, non-pharmacological, randomized study designed to compare the efficacy and safety of awake neuraxial anesthesia with sedation versus general anesthesia in frail patients undergoing elective major…
- Conditions
- Fraily, Abdominal Surgery, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- SAFE-AWARENESS (NCT07486336)
- Testing
- Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Postoperative Pain, Coronary Artery Bypass Grafting
Serratus Anterior Plane and PECS II Blocks After Coronary Artery Bypass Grafting
This prospective randomized placebo-controlled trial was designed to evaluate the effects of ultrasound-guided bilateral pectoralis (PECS II) and serratus anterior plane (SAP) blocks on postoperative recovery in adult patients…
- Trial name
- NCT06793436
- Testing
- Bilateral Serratus Anterior Plane Block, Bilateral PECS II Block
- Where
- Turkey (Türkiye)
- Volunteers
- 243 people
- Sponsor
- Yuzuncu Yil University
Cesarean Section Complications, Sleep Disturbance
Sleep Quality After Cesarean Delivery
Surgery causes poor sleep quality for several reasons eg. increasing stress hormonal production, pain, starvation, and environmental procedure namely noise, light, and nursing procedures.
- Conditions
- Cesarean Section Complications, Sleep Disturbance, Perioperative Complication
- Trial name
- NCT05757401
- Where
- Thailand
- Volunteers
- 286 people
- Sponsor
- Mahidol University
Ventilation Therapy; Complications
Optimal PEEP in Pediatric Patients Under 17 Years of Age.
This study aimed to investigate the differences in positive end-expiratory pressure titration in the supine and prone positions by age in pediatric patients under 17 years of age who received general anesthesia and then evaluate…
- Trial name
- NCT05726877
- Testing
- ventilation strategy
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Seoul National University Hospital
Urolithiasis
Comparison of General Anaesthesia and Sedation on the Stone Fragmentation in Lithotripsy
The aim of the study is to compare the impact intravenous sedation versus general anesthesia on the efficacy of stone fragmentation in extracorporeal shock wave lithotripsy treatment.
- Trial name
- NCT01361516
- Testing
- Anaesthesia and Lithotripsy
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Hadassah Medical Organization
Postpartum Hemorrhage
Carbetocin Versus Ergometrin in the Prevention of Postpartum Hemorrhage
In the present study will be compared Carbetocin with ergometrin in the prevention of postpartum haemorrhage (PPH) in parturients that are undergoing caesarean section and are not presenting risk factors for PPH.
- Trial name
- NCT04300452
- Testing
- Carbetocin, Ergometrine Maleate
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Intubation;Difficult, Awake Intubation
Airtraq Versus Fiberoptic for Awake Tracheal Intubation
The airway management is a vital act in anesthesia. The gold standard technique for planned very difficult intubation is nasotracheal fiberoptic intubation. The success rate with this procedure is 98.8%.
- Conditions
- Intubation;Difficult, Awake Intubation, Airway Complication of Anesthesia
- Trial name
- NCT03539185
- Testing
- Videolaryngoscope Airtraq, Fiberoptic bronchoscope
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Caen
General Anesthesia, Geriatric Patient
Sevoflurane and Propofol Anesthesia on Postoperative Delirium
Delirium is defined as an acute onset and fluctuating course of mental status change with inattention and an altered level of consciousness.
- Trial name
- NCT01995214
- Testing
- Propofol, Sevoflurane
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Huazhong University of Science and Technology
Regional Anesthesia Morbidity, Postoperative Pain
Approach to Continuous Sciatic Nerve Block for Orthopedic Procedures in Day Surgery With Two Different Techniques
We will enroll patients submitted to feet elective orthopaedic surgery that require analgesia through continuous peripheral nerve block (CNPB) of the sciatic nerve.
- Trial name
- NCT02029404
- Testing
- Tibial nerve group, Tibial peroneal nerve group
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
Blood Pressure, Intraoperative Hypotension
Perioperative Personalized Blood Pressure Management: IMPROVE-multi
Rates of major complications and mortality in the first weeks after surgery remain very high: postoperative mortality is still around 2% in central Europe and the United States.
- Conditions
- Blood Pressure, Intraoperative Hypotension, Postoperative Complications, Surgery
- Trial name
- IMPROVE (NCT05416944)
- Testing
- Personalized blood pressure management
- Where
- Germany
- Volunteers
- 1,272 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Neuromuscular Block
Sugammadex and Neostigmine at Shallow Neuromuscular Blockade
This study is designed to compare recovery times after reversal of a residual neuromuscular block (TOF-ratio 0.5) with different doses of either neostigmine or sugammadex.
- Trial name
- SUNDRO (NCT00895609)
- Testing
- Sugammadex, Neostigmine, Saline
- Where
- Germany
- Volunteers
- 99 people
- Sponsor
- Technical University of Munich
PONV, Opioid Use
Opioid Free Versus Opioid Balanced Anesthesia
OPIOID FREE VERSUS OPIOID BALANCED ANAESTHESIA IN MIDDLE EAR SURGERY AIM OF THE WORK Primary aim: To compare between opioid and opioid free anaesthesia on post-operative nausea and vomiting in middle ear surgery Secondary aim…
- Trial name
- NCT03809949
- Testing
- Fentanyl Opioid anesthesia, Saline Nonopioid anesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- University of Alexandria
Delirium on Emergence
Post Anesthesia Emergence and Behavioral Changes in Children Undergoing MRI
Children who receive general anesthesia may become agitated (emergence delirium) in the recovery period. This occurs more often after inhalational anesthetics, particularly sevoflurane and desflurane than after propofol.
- Trial name
- NCT02111447
- Testing
- Propofol, Sevoflurane, Isoflurane
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- State University of New York at Buffalo
Elective Cesarean Section, Preeclampsia
Ultrasonography for Fluid Assessment in Parturients With Preeclampsia Undergoing Cesarean Section
Preeclampsia is a multifocal syndrome reported in 2-8 % of pregnancies. It is diagnosed in the second half of pregnancy by two separate measurements of systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg…
- Trial name
- NCT04370847
- Testing
- Spinal Anesthesia, Intrathecal Bupivacaine, Intrathecal Fentanyl
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Post Operative Pain, Regional Anesthesia
Sub Omohyoid Suprascapular Nerve Block Versus Interscalene Nerve Block
Shoulder surgery can be very painful surgery after which the use of opioids is often required. The well-known side-effects of opioids (e.g.
- Conditions
- Post Operative Pain, Regional Anesthesia, Nerve Block
- Trial name
- NCT05796778
- Testing
- subomohyoid plane block, Interscalene brachial plexus block
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Minia University
Retained Products of Conception, Hysteroscopy
Predictors of Successful Office Operative Hysteroscopy Using a Mini-Resectoscope
The goal of this observational study is to identify predictors of successful removal of benign intrauterine pathology using a mini-resectoscope during office operative hysteroscopy without anesthesia in adult women with suspected…
- Conditions
- Retained Products of Conception, Hysteroscopy, Endometrial Polyp Benign, Endometrial Polyp
- Trial name
- NCT07875985
- Testing
- Office Operative Hysteroscopy Using the Karl Storz Mini-Resectoscope Without Anesthesia
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Pain, Postoperative, Anesthesia, Local
Improving Pain Relief Following Laparoscopic Ventral Hernia Repair
Aim The general aim of this study is to improve post-operative pain and reduce morphine consumption following laparoscopic ventral hernia repair (LVHR).
- Conditions
- Pain, Postoperative, Anesthesia, Local, Hernia, Ventral, Laparoscopy
- Trial name
- NCT02785276
- Testing
- AutoFuser Pain Pump, Ropivacaine, Normal Saline (0.9%)
- Where
- New Zealand
- Sponsor
- University of Auckland, New Zealand
Adverse Effect
Phenylephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia
The purpose of this study is to investigate the suitable infusion dose of phenylephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04576663
- Testing
- Normal saline, Phenylephrine
- Volunteers
- 95 people
- Sponsor
- General Hospital of Ningxia Medical University
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