Clinical trials: Anesthesia Conduction
Anesthesia
Gaze Training on Task Performance Regional Anaesthesia
Regional anaesthesia is the performance of spinal, epidural or peripheral nerve blocks to allow patients to undergo surgery awake and to provide post-operative pain relief.
- Trial name
- NCT04426227
- Testing
- Gaze training, Discovery learning
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Mastectomy, Mastectomy Plus Axillary Lymph Node Dissection
Effect of Serratus and Pectoralis II Plane Block Versus Pectoralis II Alone on Acute Postoperative Pain After Mastectomy
The goal of this randomized controlled clinical trial is to determine whether adding a serratus anterior plane block (SAPB) to a pectoralis II (PECS II) block improves pain relief and reduces the need for opioids in adult women…
- Conditions
- Mastectomy, Mastectomy Plus Axillary Lymph Node Dissection, Nerve Block; Pain Medication, Pectoralis Nerve Block
- Trial name
- PECS (NCT07881237)
- Testing
- Serratus Anterior Plane Block (SAPB) group, Pectoral nerve block (PECS)
- Where
- Lebanon
- Volunteers
- 80 people
- Sponsor
- Lebanese American University
ERAS
Effect of Regional Anesthesia on Enhanced Recovery After Spine Surgeries
This study will be carried out on 80 patients who will be presented for different spine surgeries under general anesthesia and regional anesthesia technique in Tanta university hospitals.
- Trial name
- NCT04586257
- Testing
- Erector spinae plane block, Throacolumbar interfacial plane block
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Tanta University
Kidney Transplant; Complications, Pain, Postoperative
Postoperative Pain Control Following Renal Transplant
This study aims to compare the effectiveness of a regional anesthetic block vs systemic intravenous (IV) lidocaine in controlling post-operative pain in kidney transplantation patients.
- Trial name
- NCT05044429
- Testing
- Intravenous Lidocaine, Transversus abdominis plane (TAP) block, Quadratus Lumborum (QL) Block
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- George Washington University
Colon Cancer
Regional Anesthesia in Colon Rectal Surgery
This study will compare recurrence rates in patients with colorectal cancer who will be randomly assigned to epidural anesthesia/analgesia combined with general anesthesia or to general anesthesia followed by opioid analgesia.
- Trial name
- NCT00684229
- Testing
- Regional anesthesia and analgesia, general anesthesia followed by opioid analgesia
- Where
- 3 sites in United States, Argentina and 1 more
- Sponsor
- The Cleveland Clinic
Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Ankle Fracture - Lateral Malleolus
Rebound Pain Following Regional Anaesthesia for Ankle Fracture Surgery
Regional anaesthesia is a commonly used and effective analgesic modality in orthopaedic surgery. The benefits of peripheral nerve blocks (PNB) include better pain relief, limited opioid consumption and high patient…
- Conditions
- Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Ankle Fracture - Lateral Malleolus, Ankle Fracture - Medial Malleolus, Rebound Pain
- Trial name
- NCT06864312
- Testing
- continuous infusion of levobupivacaine, oxycodone
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- University College Cork
Postoperative Pain, Acute, Regional Anesthesia
Comparation of Bilateral and Unilateral Erector Spinae Plane Block
Although laparoscopic cholecystectomy is a minimally invasive surgery with many advantages, it is one of the operations with high postoperative pain scores. Opioids are frequently used to prevent postoperative pain.
- Conditions
- Postoperative Pain, Acute, Regional Anesthesia, Multimodal Analgesia
- Trial name
- NCT05152602
- Testing
- Bilateral Erector spinae plane block, Unilateral Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara City Hospital Bilkent
Channelopathies, Brugada Syndrome
Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies
Patients with cardiac channelopathies needing restorative dental treatment will be included in two sessions of the study, using local dental anesthetic: lidocaine 2% with epinephrine and lidocaine 2% without vasoconstrictor.
- Conditions
- Channelopathies, Brugada Syndrome, Long QT Syndrome, Ventricular, Tachycardia
- Trial name
- SLDAPCC (NCT03182777)
- Testing
- Dental restorative procedure
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- University of Sao Paulo General Hospital
Osteo Arthritis Knee, Gonarthrosis
The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement
Total knee replacement (TKR) is considered the most effective and safe method of radical treatment of late stages of knee osteoarthritis.
- Trial name
- NCT05487053
- Testing
- Single-shot adductor canal block, Continuous femoral nerve block
- Where
- Russia
- Volunteers
- 220 people
- Sponsor
- Negovsky Reanimatology Research Institute
Lower Limb Injuries, Fracture
Regional Anaesthesia for Painful Injuries After Disasters
The goal of the RAPID study is to fundamentally transform the way serious injuries are managed after earthquakes and other disasters by introducing a novel and cost-effective method for pain control.
- Trial name
- RAPID (NCT02698228)
- Testing
- Bupivacaine (femoral nerve block), Morphine, Ultrasound
- Sponsor
- Epicentre
Chronic Post-surgical Pain, Acute Postoperative Pain
CROPS Study: Chronification of Post-Surgical Pain and Risk Assessment
Chronic post-surgical pain (CPSP) represents a major clinical problem associated with impaired functional recovery, reduced quality of life, prolonged opioid use, and increased healthcare utilization.
- Conditions
- Chronic Post-surgical Pain, Acute Postoperative Pain, Cardiac Surgery
- Trial name
- CROPS (NCT07629453)
- Testing
- Standard Multimodal Opioid-Based Analgesia, Regional Anesthesia-Based Analgesia
- Volunteers
- 180 people
- Sponsor
- Kočan Ladislav
Post-operative Pain, Gynecologic Surgery
Ultrasound Guided Posterior Quadratus Lumborum Block for Postoperative Analgesia in Gynecologic Surgery
The challenge to achieve adequate analgesia has led to the development of directed, multi-modal protocols specific to management of post-laparoscopy pain in effort to decrease the amount of additional administration of narcotic…
- Conditions
- Post-operative Pain, Gynecologic Surgery, Regional Anesthesia
- Trial name
- NCT04549090
- Testing
- QL (quadratus lumborum) block administration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pedram Bral
Other Surgical Procedures
Ultrasound-guided Axillary Plexus Block - Dose Reduction of Prilocaine
Clinical aim: Does reducing the dose of local anesthetic in ultrasound-guided axillary plexus anesthesia have any effect on the success rate and additional parameters of block quality? Methodology: In this prospective cohort…
- Trial name
- NCT01309360
- Testing
- midazolam, prilocaine 1%
- Volunteers
- 120 people
- Sponsor
- Helios Research Center
Ventral Hernia, Postoperative Pain
Evaluation of Ultrasound-guided Erector Spinae Block for Postoperative Analgesia in Laprascopic Ventral Hernia Repair.
Ventral hernia repair is associated with significant postoperative pain, and regional anesthetic techniques are of potential benefit.
- Conditions
- Ventral Hernia, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT04438369
- Testing
- Erector Spinae Plane Block
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Ostfold Hospital Trust
Postoperative Pain, Anesthesia
Regional Anesthesia Versus General Anesthesia
Patients undergoing laparoscopic gynecological surgery will receive regional anesthesia or general anesthesia with endotracheal intubation.
- Trial name
- NCT03830086
- Testing
- Midazolam, Sufentanil, Propofol
- Where
- 2 sites in Italy
- Volunteers
- 28 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Regional Anaesthesia
Comparison Between Ultrasound Guided Femoral 3 in 1 Block Versus Blind Fascia Iliaca Block Before Spinal Anaesthesia
This study aimed to evaluate the efficacy of ultrasound guided femoral 3 in 1 block versus the blind technique single shot fascia iliaca compartment block as an analgesia method in patients prior positioning for spinal…
- Trial name
- IKH (NCT03139617)
- Testing
- Fascia Iliaca Compartment Block (FICB), 3 in 1 femoral block (FNB)
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- Universiti Sains Malaysia
Injuries, Hand, Anesthesia Conduction
Cardiovascular Safety Research: Bupivacaine With Vasoconstrictor Versus Ropivacaine in Brachial Plexus Block
The purpose of this study is to determine if bupivacaine (75% levobupivacaine plus 25% racemic bupivacaine) with vasoconstrictor is effective and safety as ropivacaine in brachial plexus block for orthopedic surgery.
- Conditions
- Injuries, Hand, Anesthesia Conduction, Anesthetics, Local
- Trial name
- NCT00523289
- Testing
- Bupivacaine, Ropivacaine
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Anxiety, Stress (Psychology)
Cellphone Access for Lowered Maternal Anxiety and Stress in Cesarean Sections
This study looks at whether allowing mothers to use their personal cellphone during a planned cesarean section (C-section) under spinal anesthesia can reduce stress and anxiety and improve their overall birth experience.
- Trial name
- CALMAS-CS (NCT07759726)
- Testing
- Cell Phone Use
- Where
- Lebanon
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Regional Anesthesia, Pain, Postoperative
Analgesic Efficacy of Single-shot Erector Spinae Block for Thoracic Surgery
The erector spinae plane (ESP) block is a novel regional anesthetic technique for the treatment of thoracic, cervical, and abdominal pain.
- Trial name
- AnESTh (NCT03419117)
- Testing
- ESP block
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hip Surgery, Postoperative Pain Management
Comparison of Intermittent Bolus vs. Continuous Infusion PENG Block for Postoperative Pain in Hip Surgery
This retrospective study evaluates the effects of two different administration methods of the Pericapsular Nerve Group (PENG) Block on postoperative pain control, opioid consumption, and recovery in patients undergoing hip…
- Conditions
- Hip Surgery, Postoperative Pain Management, Pericapsular Nerve Group Block (PENG Block), Regional Anesthesia
- Trial name
- ICPENG (NCT06834243)
- Testing
- Intermittent Bolus PENG Block, Continuous Infusion PENG Block
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Onur Baran
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