Clinical trials: Anesthesia Management
Anesthesia, Pain Management
NoL Monitor Performances of Nociceptive and Non-nociceptive Stimuli Discrimination During Robotic Surgery
Anesthesia quality and safety have improved over the past decades, thanks to improved monitoring devices. No nociception monitoring is currently part of the standard of care.
- Trial name
- ROBOTNOL (NCT04566536)
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Airway Management Assessment, Supraglottic Airways
The Insertion of I-gel and Classic LMA in Different Head Positions in Elderly Patients
This prospective, randomized, double-blind clinical study aims to evaluate the insertion success of two supraglottic airway devices, the classic Laryngeal Mask Airway (LMA) and the I-gel, in different head and neck positions in…
- Conditions
- Airway Management Assessment, Supraglottic Airways, Supraglottic Airways for General Anesthesia, Laryngeal Mask Airways
- Trial name
- NCT07027293
- Testing
- STANDART HEAD POSITION, HEAD ROTATION POSITION, Classic laryngeal mask airway (LMA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Cicatrix
Fractional Laser Assisted Topical Anesthesia
The purpose of this study is to assess the efficacy of skin anesthesia using fractional laser assisted delivery of articaine hydrochloride 40 mg/ml and epinephrine 10 µg/ml solution (AHES) compared to standard anesthesia with…
- Trial name
- NCT02548533
- Testing
- AFXL, AHES, EMLA cream
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- Netherlands Institute for Pigment Disorders
Amputation, Anesthesia, Local
Use of Long-acting Bupivacaine In Lower Extremity Amputation
The purpose of this investigator-initiated study is to assess the use of liposomal bupivacaine in major extremity amputation and its effects on post-operative opioid narcotic use, length of stay, and in-hospital costs.
- Conditions
- Amputation, Anesthesia, Local, Opioid Use
- Trial name
- NCT04360421
- Testing
- Liposomal bupivacaine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Loma Linda University
Airway Management
Compare the Efficacy of Different Laryngeal Mask Size Selection Methods in General Anesthesia in Children
The laryngeal mask is widely used in general anesthesia in children. Selection of an appropriately sized laryngeal mask airway (LMA) is critical to ensure safe and effective use of the device.
- Trial name
- NCT03845998
- Testing
- use the three-finger method, use the weight-related method
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Analgesia, Pain, Postoperative
Comparison Between the Caudal Block and Other Methods of Postoperative Pain Relief in Children Undergoing Circumcision
Prospective, randomized, case-controlled trial study. Observation post-operatively: Aims: This study aimed to compare the effectiveness of the caudal block CB with other methods of postoperative pain release.
- Conditions
- Analgesia, Pain, Postoperative, Pain, Acute
- Trial name
- paincontrol (NCT06086106)
- Testing
- caudal block, Dorsal Penile Nerve Block DPNB, Systemic opioids
- Where
- Bahrain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Anesthesia, General, Fluid Therapy
Management of Intraoperative Fluids in Ambulatory Surgery
This is a single-center prospective randomized control trial (RCT) to determine whether the continuous monitoring of the plethysmographic variability index (PVI) during low-risk surgeries, can be used to optimize the…
- Conditions
- Anesthesia, General, Fluid Therapy, Ambulatory Surgical Procedures
- Trial name
- MIFAS (NCT03193320)
- Testing
- Fluid therapy protocol
- Where
- Venezuela
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- Policlinica Metropolitana
Anesthesia, Sedation
Automated Postoperative Sedation After Cardiac Surgery
This study compares automated administration of propofol and remifentanil guided by the Bispectral index (BIS) versus manual administration for sedation after cardiac surgery.
- Conditions
- Anesthesia, Sedation, Surgery, Cardiac
- Trial name
- SEPOCA (NCT03517735)
- Testing
- EasyTiva (algorithm is the property of Medsteer SAS), Propofol, Remifentanil
- Where
- France
- Volunteers
- 7 people
- Sponsor
- CMC Ambroise Paré
Airway Management, Tracheal Intubation
Comparison of Intubation Using Video Laryngeal Mask and Video Laryngoscope in Elective Surgical Patients
This study compares two airway devices that are commonly used during elective surgery: the video laryngeal mask airway (VLM) and the video laryngoscope (VLS). Both are part of routine anesthesia practice.
- Conditions
- Airway Management, Tracheal Intubation, Elective Surgeries, Videolaryngoscopy
- Trial name
- NCT07057908
- Testing
- Video Laryngoscope Intubation with Bougie, Video Laryngeal Mask Airway (SaCoVLM) Intubation with Bougie
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people
- Sponsor
- Samsun University
Female, Male
Towards a Sex-specific "Female Enhanced Recovery After Cardiac Surgery'' (F-ERAS) Pathway:
The aim of this study is to evaluate the differences between men and women undergoing cardiac surgery. We will look at perioperative factors such as body weight, body surface area, previous medical history, pharmacokinetics…
- Conditions
- Female, Male, Surgery,Cardiac
- Trial name
- F-ERAS (NCT06175650)
- Testing
- Cardiac surgery
- Where
- Netherlands
- Volunteers
- 5,500 people
- Sponsor
- Jennifer Breel
Postoperative Pain, Open Nephrectomy
Modified External Oblique Intercostal Plane Block Versus Erector Spinae Plane Block for Open Nephrectomy
This prospective, randomized, assessor-blinded clinical trial aims to compare the postoperative analgesic efficacy of ultrasound-guided Erector Spinae Plane Block (ESPB) and Modified External Oblique Intercostal Plane Block…
- Trial name
- EOIPB-ON (NCT07726550)
- Testing
- Erector Spinae Plane Block, Modified External Oblique Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Namik Kemal University
Atrial Fibrillation, Ablation
The Deep Sedation for Ablation Study
Catheter ablation (CA) is an established therapeutic option for patients with symptomatic atrial fibrillation (AF). During the procedure, patients are usually sedated and analgesized, most commonly by administration of Propofol…
- Conditions
- Atrial Fibrillation, Ablation, Sedation, Propofol
- Trial name
- NCT03844841
- Testing
- Propofol, Dexmedetomidine
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postoperative Pain Management
Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Plus Biceps Femoris Short Head Block in Patients Undergoing Knee Arthroscopy
This prospective, randomized, controlled, and multicenter clinical study aims to compare the postoperative analgesic efficacy of two regional anesthesia techniques commonly used in knee arthroscopy: adductor canal block (ACB) and…
- Trial name
- bifes knee (NCT07242339)
- Testing
- Adductor Canal Block (ACB) Only, biceps femoris short head block + Adductor Canal Block (ACB)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Surgery
AI-driven Clinical Decision Support for Perioperative Blood Orders
20 million patients have surgery in the United States every year, with approximately 1 million of those patients requiring life-saving blood transfusion.
- Trial name
- SPATH (NCT07223853)
- Testing
- S-PATH clinical decision support system, Usual care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Anesthesiology Management
Recovery From Anesthesia After Robotic Assisted Radical Cystectomy
Robot-assisted radical cystectomy (RARC) requires specific surgical conditions: steep Trendelenburg position, prolonged pneumoperitoneum, effective neuromuscular block until the final stages of surgery.
- Trial name
- NCT03144453
- Testing
- Sugammadex Injectable Product, Neostigmine, Atropine
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Regina Elena Cancer Institute
Lumbar Spinal Fusion
Efficacy of TLIP Block for Postoperative Analgesia of Lumbar Spinal Fusion
Spinal surgery is associated with severe pain in the immediate postoperative period. In a recent study evaluating pain intensity on the first day after surgery in a large range of surgical procedures, among the six most painful…
- Trial name
- ETLA (NCT04593953)
- Testing
- TLIP
- Where
- 2 sites in France
- Volunteers
- 94 people
- Sponsor
- CMC Ambroise Paré
Anesthesia, Extubation
Anesthesia Quality Improvement and Patients With Planned ICU Admission
Intensive care unit (ICU) is an important part of perioperative management for high-risk patients but is associated with higher medical costs. Improper ICU admission may produce overtreatment without beneficial effects.
- Conditions
- Anesthesia, Extubation, Intensive Care Unit, Postoperative Complications
- Trial name
- NCT05626153
- Testing
- Routine anesthesia care, Improved anesthesia care
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Peking University First Hospital
Traumatic Rib Fracture(s), Traumatic Rib Fracture
Erector Spinae Plane vs Serratus Anterior Plane Catheter Infusions for Acute Pain Management in Patients With Traumatic Rib Fractures
Rib fractures happen in about 10-20% of patients with blunt trauma and can be serious, with higher death rates in older adults. These injuries often lead to lung problems like pneumonia, collapsed lung areas (atelectasis), fluid…
- Trial name
- NCT07756047
- Testing
- Erector spinae plane catheter, Serratus plane catheter
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- Sunnybrook Health Sciences Centre
Anesthesia Ergonomics, Anesthesia Airway Management
Effect of Anesthesia Equipment Position on Anesthesiologists' Performance
The purpose of this study is to determine if the position of the anesthesia machine affects the ability of anesthesiologists to manage a crisis situation and perform critical tasks.
- Conditions
- Anesthesia Ergonomics, Anesthesia Airway Management, Simulation in Training Center
- Trial name
- NCT07518849
- Testing
- Simualted laryngospasm crisis
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Mask Ventilation, General Anesthesia
Prediction of Difficult Mask Ventilation Using 3D-Facescan and Machine Learning
The aim of this study is to prove feasibility and assess the diagnostic performance of a machine learning algorithm that relies on data from 3D-face scans with predefined motion-sequences and scenes (MASCAN algorithm), together…
- Trial name
- MASCAN (NCT05411406)
- Where
- Germany
- Volunteers
- 423 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf