Clinical trials: Anesthesia Spinal
Caesarean Section, Spinal Anesthesia
Evaluating the Effectiveness of Ondansetron Versus Dexamethasone Versus Placebo for the Control of Intraoperative Nausea and Vomiting in Patients Undergoing Lower-segment Caesarean Section Under Spinal Anesthesia
The goal of this randomized controlled trial is to evaluate the effectiveness of Ondansetron, Dexamethasone, and Placebo for intraoperative nausea and vomiting in patients undergoing caesarian section under spinal anesthesia.
- Trial name
- ODP (NCT05583214)
- Testing
- Ondansetron 8mg, Dexamethasone 8mg, Normal saline
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muhammad Mubariz
Shivering
Comparison of Prophylactic Use of Tramadol Versus Ketamine for Prevention of Post Spinal Anesthesia Shivering
The goal of this clinical trial is to compare the effectiveness of tramadol versus ketamine in preventing shivering after spinal anesthesia in adult patients (ages 20-65) undergoing elective lower abdominal or inguinoscrotal…
- Trial name
- KETRA4PSAS (NCT07043049)
- Testing
- Tramadol, Ketamine
- Where
- 2 sites in Pakistan
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Syed Muhammad Abbas
Spine Fracture
Comparison Of Deep Versus Moderate Neuromuscular Blockade on Intra-Operative Blood Loss During Spinal Surgery
Reduction of intra-operative blood loss
- Trial name
- NCT05294926
- Testing
- Rocuronium, nerve stimulator
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Assiut University
Lower Limb Surgeries
Effect of Height Based vs Conventional Dose of Spinal Anesthesia in Lower Limb Surgeries
This study aim is to compare height based dose of spinal anesthesia vs conventional dose. Hypothesis is height based dose has less hemodynamics changes compared to conventional dosing.
- Trial name
- NCT07751835
- Testing
- Height based dose of hyperbaric bupivacaine 0.5%
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Pain, Postoperative
Comparing Analgesic Effects of Wound Infiltration Using Bupivacaine, Tramadol, and Tramadol Plus Bupivacaine
The goal of this study's clinical trial is to compare in post-operative analgesic effectiveness of wound infiltration using bupivacaine, tramadol, and tramadol plus bupivacaine in patients undergoing elective cesarean section…
- Trial name
- NCT06076707
- Testing
- bupivacain-tramadol
- Where
- Ethiopia
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Wollo University
Postdural Puncture Headache
Examination of Postdural Puncture Headache Frequency, Predisposing Factors and Treatment
Post-dural puncture headache (PDPH) is one of the most important complications of neuraxial blocks and lumbar interventions for cerebrospinal fluid (CSF) examination.
- Trial name
- PDPH (NCT06394024)
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Mustafa Soner Ozcan
Cesarean Section Complications, Hemodynamic Instability
Norepinephrine in Caesarian Section
Postspinal hypotension is a frequent maternal complication in caesarian delivery under neuraxial anesthesia which is most commonly treated with the administration of phenylephrine infusion.
- Conditions
- Cesarean Section Complications, Hemodynamic Instability, Foetal Stress
- Trial name
- NCT05264870
- Testing
- Norepinephrine
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Pre-Eclampsia, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Electroencephalographic Effects of Spinal Anaesthesia During Caesarean Delivery in Preeclampsia
Neuraxial anesthesia has been associated with delayed brainstem conduction and decreasing afferent sensory transmission, thereby modifying reticulo-thalamo-cortical mechanisms regulating arousal.
- Trial name
- NCT03917342
- Testing
- EEG measure
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Procedural Sedation
Dexmedetomidine and Midazolam Nebulization as Sedation During Cesarean Delivery in Pre-eclampsia
Null hypothesis: There is no difference between the effects of nebulization of dexmedetomidine and midazolam as procedural sedation during cesarean delivery under spinal Anesthesia in pre-eclamptic parturients Alternative…
- Trial name
- NCT04873596
- Testing
- Nebulized dexmedetomidine, Nebulized midazolam
- Where
- Egypt
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Surgery Ambulatory
Spinal or Intravenous Dexmedetomidine in Ambulatory Surgery
The primary objective of this double blind randomized study is to determine the effect of dexmedetomidine on onset and duration of the sensory and motor block and on the influence on bladder function after spinal anesthesia with…
- Trial name
- NCT02282319
- Testing
- spinal dexmedetomidine 0.5 mcg, spinal chloroprocaine 40 mg, IV dexmedetomidine 0.5 mcg/kg
- Where
- 2 sites in Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Anesthesia, Anorectal Surgery
Spinal Anesthesia Versus General Anesthesia Using Laryngeal Mask Airway for Anorectal Surgeries in Prone Position
Anorectal surgeries are of the commonest elective surgeries that are performed worldwide under different types of anaesthesia. The aim of this prospective interventional study was to compare the use of general anaesthesia (GA)…
- Trial name
- NCT04214977
- Testing
- Spinal Anesthesia for Anorectal Surgeries in Prone Position, General Anesthesia Using Laryngeal Mask Airway for Anorectal Surgeries in Prone Position
- Where
- Jordan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Shivering
Role of Intravenous Dexmedetomidine in Reducing Shivering After Shivering Cesarean Section Due to Spinal Anesthesia
"After spinal anesthesia, some patients may experience shivering, which can be uncomfortable and even lead to complications. Dexmedetomidine is a medication that can help prevent or reduce this shivering.
- Trial name
- NCT06711913
- Testing
- Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Hip Replacement
Quadratus Lumborum Block Versus Fascia Iliaca Nerve Block for Patients Undergoing Total Hip Replacement
Investigators hypothesise that for patients undergoing elective total hip replacements, a single injection Transmuscular Quadratus Lumborum (TQL) block, when compared to a single injection Fascia Iliaca Block (FIB), will provide…
- Trial name
- NCT03551860
- Testing
- TQL, FIB
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
Caesarean Section
Optimization of Hemodynamic Conditions During Caesarean Section Under Spinal Anaesthesia
The purpose of this study is to determine wether intravenous Phenylephrine, administered as start bolus and following continuous infusion (specific dosage per weight), or optimal lower limb bandaging is more effective in…
- Trial name
- NCT01278238
- Testing
- Phenylephrine, Lower limb compression
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Anestesiavdelingen Baerum Sykehus
Spinal Anesthesia
Hyperbaric Prilocaine 2% vs Hyperbaric Bupivacaine 0.5% in Caesarean Section
Comparison between effects of hyperbaric bupivacaine 0.5% vs Hyperbaric prilocaine 2% in spinal anesthesia of women undergoing elective caesarean section such as onset time of sensory and motor block, duration of sensory and…
- Trial name
- NCT06680167
- Testing
- Spinal anesthesia (heavy bupivacaine 0.5%), spinal anesthesia (hyperbaric Prilocaine 2%)
- Where
- Egypt
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Sohag University
Inguinal Hernias
Ilioinguinal Nerve Block With Local Anesthetic vs. Placebo in Inguinal Hernia Repair Under Spinal Anesthesia
Postoperative pain management remains a critical area of concern in surgical practices, especially in procedures involving the lower abdomen and pelvis.
- Trial name
- NCT07049835
- Testing
- Ilioinguinal/iliohypogastric Nerve Block
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Spinal Anesthesia, Post Operative Analgesia
Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients
Lower segment C section is one of the most commonly performed surgeries worldwide. It is performed in spinal anesthesia. During Spinal Anesthesia a local anesthetic drug is administered in a space surrounding spinal cord and it…
- Trial name
- NCT07088146
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Hypotension, Spinal Anaesthesia
The Effects of Keeping the Patient in a Sitting Position for One Minute After Spinal Anesthesia
The aim of this study was to examine the effect of keeping the patient in a sitting position for 1 minute after spinal anaesthesia in elective caesarean operations, primarily on the formation of hypotension and secondarily on…
- Trial name
- NCT03834259
- Testing
- sitting position, supine position
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Anesthesia
Application of Combined Lumbar Plexus and Sciatic Nerve Block
The research is to study the effectiveness and safety of combined lumbar plexus and sciatic nerve block by the guide of peripheral nerve stimulator (PNS) in unilateral knee replacement.There have be some papers which supported…
- Trial name
- NCT02084368
- Testing
- Nerve block, Combined spinal and epidural anesthesia, Ropivacaine
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Hypotension
Measuring Cardiac Output and Stroke Volume Using the Physioflow Impedance Device in Pregnant Patients
Pregnant patients having a cesarean section (CS) under spinal anesthesia experience a variety of hemodynamic changes, such as hypotension due to decreases in cardiac output (CO), stroke volume (SV) and/or systemic vascular…
- Trial name
- NCT00573274
- Testing
- Physioflow Impedance
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital