Clinical trials: Anesthesia Spinal
Hypotension Drug-Induced
Norepinephrine Addition in Spinal Anesthesia of Caesarean Section
The objective is to compare efficacy of prophylactic norepinephrine bolus versus Infusion in prevention of hypotension which occurs frequently after spinal anesthesia for caesarean section.
- Trial name
- NASA (NCT03626454)
- Testing
- Norepinephrine Bolus, Norepinephrine infusion, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Total Knee Arthroplasty
Single-injection Adductor Canal Block for Total Knee Arthroplasty Under Spinal Anesthesia
This study evaluates the effect of the single-injection adductor canal block in patients receiving total knee arthroplasty under spinal anesthesia.
- Trial name
- NCT04400708
- Testing
- adductor canal block, control group
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Anesthesia Local
Comparison of Combined Sciatic(Winnie's) Femoral Nerve Block, and Subarachnoid Block Anesthesia for Lower Limb Surgery
60 ASA grades- I, II or III patients, undergoing lower limb surgeries, will be randomly allocated in 2 groups of 30 patients each.
- Trial name
- NCT02713685
- Testing
- Subarachnoid block, combined Femoral and Sciatic nerve block
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
Atelectasis, Cesarean Section
The Effect of Oxygen Therapy on Atelectasis
In pregnancy, cephalal shift of the diaphragm caused by the enlarged uterus reduces the functional residual capacity and may increase the closure volume and predispose the pregnant woman to airway closure, leading to atelectasis.
- Conditions
- Atelectasis, Cesarean Section, Hypotension
- Trial name
- NCT05509764
- Testing
- lung ultrasound score
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Postoperative Pain, Pain
Comparison of Analgesic Efficacy of Intrathecal Bupivacaine Versus Bupivacaine Plus Dexmedetomidine in Patients Undergoing Orthopedic Surgeries.
Clinical Trial Overview: Intrathecal Bupivacaine vs. Bupivacaine + Dexmedetomidine Primary Objective Duration of Analgesia:** To compare the mean duration of postoperative pain relief between hyperbaric bupivacaine alone versus…
- Conditions
- Postoperative Pain, Pain, Orthopaedic Surgery, Anesthesia, Spinal
- Trial name
- NCT07866508
- Testing
- Dexmedetomidine plus Hyperbaric Bupivacaine, Hyperbaric bupivacaine % 0.5
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Post-spinal Shivering
Prophylactic Tramadol Versus Magnesium Sulphate for Prevention of Post-Spinal Shivering
This randomized controlled trial compared prophylactic intravenous tramadol and magnesium sulphate for the prevention of post-spinal shivering among women undergoing elective cesarean section under spinal anesthesia.
- Trial name
- TRAM-MAGS (NCT07838662)
- Testing
- Tramadol, Magnesium Sulphate
- Where
- Pakistan
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Punjab Rangers Teaching Hospital Lahore
Postdural Puncture Headache
Effect of Coffee on Postdural Puncture Headache After Cesarean Section
The purpose of this study is to investigate the effects of postoperative coffee consumption on postdural puncture headache (PDPH) and analgesic use in women undergoing cesarean section with spinal anesthesia.
- Trial name
- NCT07410741
- Testing
- Coffee Consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Postoperative Pain
The Analgesic Efficacy of Bilateral Erector Spinae Plane Block in Comparison With Intrathecal Morphine After Elective Cesarean Section
The aim of this study was to assess the analgesic efficacy of bilateral erector spinae plane block in comparison with intrathecal morphine after elective cesarean section under spinal anesthesia.
- Trial name
- NCT03935412
- Testing
- Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Anesthesia, Spinal
The Effect of Spinal Anesthesia on Hemodynamics
In this study, it was planned to provide more stable hemodynamics in geriatric patients with low-dose spinal anesthesia. We will compare 7.5mg hyperbaric bupivacaine with 5mg hyperbaric bupivacaine.
- Trial name
- NCT05896631
- Testing
- 7.5 mg hyperbaric bupivacaine, 5 mg hyperbaric bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Smoking Cigarette, Spinal Anaesthesia
Does Smoking Effect Spinal Anesthesia?
Background In the last 10 years, the rate of smoking in women of childbearing age has increased gradually. The smoking affects general anesthesia negatively.
- Conditions
- Smoking Cigarette, Spinal Anaesthesia, Pregnancy, Cesarean Section
- Trial name
- NCT05343845
- Testing
- Observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Hypotension
Management Arterial Hypotension During Planned Caesarean Section, Intravenous Ephedrine/Phenylephrine Mixture Versus Intravenous Baby Noradrenaline
Comparison of two practices of obstetrical services between the CHU of Clermont Ferrand and the HFME Lyon-Bron in the management of arterial hypotension during an elective cesarean section
- Trial name
- ARTEMIS (NCT05513066)
- Where
- 2 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Shivering Caused by Spinal Anesthesia
COMPARISON OF INTRAVENOUS DEXMEDETOMEDINE AND TRAMADOL FOR POST OPERATIVE SHIVERING AFTER SPINAL ANESTHESIA FOR CAESAREAN SECTION
To compare the mean time of cessation of post-operative shivering after receiving intravenous dexmedetomidine versus tramadol in patients undergoing caesarean delivery under spinal anaesthesia.
- Trial name
- NCT07332572
- Testing
- Tramadol, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Healthy
Dexamethasone Intravenous Versus Intrathecal in Spinal Anesthesia
The purpose of this study is to compare the the effect of intravenous and the intrathecal dexamethasone when added to spinal anesthesia in cesarean section.
- Trial name
- NCT05470530
- Testing
- Dexamethasone
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy Female Volunteer
Fentanyl Versus Midazolam as an Adjunct to Spinal Anesthesia
It is well documented in the practice of anesthesia the effectiveness of bupivacaine when added with other adjuvants including midazolam, opioids, and ketamine during neuraxial spinal block for cesarean delivery, however…
- Trial name
- Spinal Block (NCT06917898)
- Testing
- Spinal Anesthesia with Bupivacaine and Fentanyl, Spinal Anesthesia with Bupivacaine and Midazolam
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Cesarean Section
The Effects of a Head Elevated Ramped Position During Elective Cesarean Delivery After Combined Spinal Epidural (CSE) Anesthesia
This study will randomly allocate 180 women undergoing elective C-sections under combined spinal epidural (CSE) Anesthesia at BC Women's Hospital to one of three groups: Standard Pillow under Head (Control), Head Elevated in…
- Trial name
- NCT01161693
- Testing
- TROOP® elevation pillow
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pyrexia, Abdominal Delivery
Combined Anesthesia for Labor and Maternal Temperature
Maternal intra-partum fever commonly complicates the process of labour. Its occurrence is often regarded as being synonymous with the presence of chorioamnionitis.
- Trial name
- feveranalg (NCT01078519)
- Testing
- Combined epidural and spinal anesthesia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Pain
Effect of Shotblocker on Procedure-related Pain, Satisfaction and Comfort in Patients Receiving Spinal Anesthesia
Although spinal anesthesia, which is increasingly common today, is a fast and reliable method, many patients are afraid of this procedure due to their fear of needles.
- Trial name
- NCT06163027
- Testing
- Shotblocker, Shotblocker(Plasebo)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Hemodynamic Stability
Comparative Analytical Study of Intravenous Bolus Dose of Mephentermine and Phenylephrine for Hemodynamic Stability During Elective Cesarean Section Under Spinal Anesthesia at KIST Medical College and Teaching Hospital
Hemodynamics changes with spinal anesthesia is mainly due to sympathetic block which causes mainly hypotension \& bradycardia. Post spinal hypotension usually leads to various adverse maternal and fetal outcomes.
- Trial name
- NCT05706727
- Testing
- Intravenous bolus dose of Mephentermine and mephentermine, intravenous bolus dose of phenylephrine 50 mcg
- Where
- Nepal
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- KIST Medical and Teaching Hospital
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean Section
The purpose of the study is to determine if norepinephrine is more effective as a continuous intravenous (IV) infusion compared to continuous IV ephedrine associated with crystalloid loading for maintaining blood pressure during…
- Conditions
- Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension, Complications; Cesarean Section
- Trial name
- NCT02477501
- Testing
- Norepinephrine, Ephedrine
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Hypotension
Closed-loop Double-vasopressor Automated System to Treat Hypotension During Spinal Anaesthesia for Caesarean Section
Hypotension occurs commonly during spinal anesthesia for caesarean section with maternal and fetal adverse effects. The investigators developed a double-vasopressor automated system incorporating continuous non-invasive arterial…
- Trial name
- NCT04025918
- Testing
- Vasopressor automated delivery system, Phenylephrine, Ephedrine
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital