Clinical trials: Anesthesia for Cesarean Delivery
Hypotension
Can Passive Leg Raise Prevent Spinal Anesthesia-induced Hypotension During Cesarean Section?
All over the world, spinal anesthesia is widely used in cesarean sections due to its superiority over general anesthesia. Due to reasons such as increased sensitivity to local anesthetics and increased intra-abdominal pressure in…
- Trial name
- NCT04673253
- Testing
- Passive leg Raise, control
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Antalya Training and Research Hospital
Cesarean Section, Hypotension
Prediction of Hypotension During Cesarean Delivery Using Positional Change of Hemodynamic Parameters
This was a prospective observational study between January 2022 and June 2022. The investigators included parturients aged 18 to 45 years, consenting, classified ASA II and III, scheduled for elective or emergency cesarean…
- Conditions
- Cesarean Section, Hypotension, Anesthesia, Spinal, Heart Rate
- Trial name
- NCT05685212
- Where
- Tunisia
- Volunteers
- 121 people
- Sponsor
- Mongi Slim Hospital
Anesthesia, Spinal
Spinal Marginally Hyperbaric Ropivacaine for Cesarean Delivery
BACKGROUND: One previous study has confirmed that the marginally hyperbaric solutions of bupivacaine can maintain good quality of anesthesia and get a more steadily hemodynamic status than commonly hyperbaric solutions, some…
- Trial name
- NCT03142880
- Testing
- hyperbaric ropivacaine
- Volunteers
- 120 people
- Sponsor
- Qilu Hospital of Shandong University (Qingdao)
Cesarean Section, Obese Parturient
"Ultrasound vs. Landmark Technique for Spinal Anesthesia in Obese Women Undergoing Cesarean Section"
The goal of this clinical trial is to evaluate whether the ultrasound-assisted technique improves the accuracy and safety of spinal anesthesia compared to the traditional landmark technique in obese women undergoing a cesarean…
- Conditions
- Cesarean Section, Obese Parturient, Ultrasound Guided Subarachnoid Block
- Trial name
- NCT07601542
- Testing
- Landmark-Guided Spinal Anesthesia, Ultrasound-Assisted Spinal Anesthesia
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangladesh Medical University
Spinal Anesthesia Induced Hypotension, Caeserian Section
AI Prediction of Post-Induction Hypotension in Cesarean Sections With Spinal Anesthesia
The cesarean section, medically necessary for both the mother and the baby in certain cases, is a life-saving operation.The most commonly used anesthesia method worldwide is spinal anesthesia.
- Trial name
- NCT06158542
- Testing
- Spinal Anesthesia, Blood Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 370 people
- Sponsor
- Hacettepe University
Postdural Puncture Headache, Postoperative Nausea and Vomiting
Ondansetron and Dexamethasone for Prevention of PDPH, Nausea, and Vomiting
This prospective, randomized, double-blind, placebo-controlled study was conducted at the Obstetrics and Gynecology Department of El-Minia University Hospital from October 2018 to October 2019.
- Conditions
- Postdural Puncture Headache, Postoperative Nausea and Vomiting, Obstetric Anesthesia Problems
- Trial name
- PDPH-N/V (NCT07068230)
- Testing
- Ondansetron 8mg, Dexamethasone, Saline
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Hypoxia, Hyperoxia
Different Preoxygenation Methods In Cesarean Section
The study aimed to evaluate different preoxygenation methods (tidal volume for 3 minutes and 4 deep breaths) in pregnant women with oxygen reserve index (ORI).
- Trial name
- NCT05395975
- Testing
- Oxygen Reserve Index
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Hypotension
Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hypotension After Spinal Anesthesia in Parturients
The purpose of this study is to compare the effect of TEAS on hypotension after spinal anesthesia in patients undergoing cesarean section
- Trial name
- THSAP (NCT01930227)
- Testing
- TEAS, Non-acupoint stimulation
- Where
- 2 sites in China
- Volunteers
- 150 people
- Sponsor
- wangqiang
Pre-Eclampsia
Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia
The purpose of this study is to compare the effect of albumin versus routine care on hemodynamic response and stability in pre-eclamptic patients during cesarean delivery.
- Trial name
- NCT06107335
- Testing
- Human Albumin (colloid), Lactated Ringer's Injection (crystalloid), Edwards HemoSphere monitor with ClearSight-Acumen finger cuff
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- The University of Texas Health Science Center, Houston
Anaesthesia, Spinal
Pain Control and Side Effects in Cesarean Section Anesthesia: Comparison of Intrathecal Morphine and Fentanyl
Intrathecal opioids are frequently combined with local anesthetics to optimize spinal anesthesia for cesarean delivery. Fentanyl, a lipophilic opioid, offers rapid onset and enhanced intraoperative analgesia.
- Trial name
- FvMinSACS (NCT07144410)
- Testing
- fentanyl + morphine, fentanyl
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Oradea
Acceptability of Health Care
The Correlation Between Family Member Presence and The Consent for Regional Anaesthesia for Caesarean Section
Patient's safety and satisfaction are major concerns of anesthesiologists and obstetricians. According to evidence guidelines, and quality markers, regional anesthesia is preferred over general in obstetric surgery.
- Trial name
- BSU (NCT04614220)
- Testing
- Presence of Family member
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
Postoperative Pain After Cesarean Section
TAP vs. ESP Blocks for Post-Cesarean Analgesia
This study compares the effectiveness of two ultrasound-guided nerve blocks (TAP block and ESP block) versus standard pain management for relieving pain after a planned cesarean section.
- Trial name
- RCT-TAP-ESP-CS (NCT07853482)
- Testing
- Ropivacaine, Ultrasound-guided Nerve Block, Ketoprofen and Paracetamol
- Where
- Russia
- Volunteers
- 162 people
- Sponsor
- Maternity Hospital - State Budgetary Institution of the Rostov Region, Taganrog
Caesarean Section, Anesthesia; Reaction
The Effects of Different Anesthetic Techniques on QT, Corrected QT (QTc), and P Wave Dispersions in Cesarean Section
This study evaluates the effects of different anesthetic techniques on QT, QTc, and Pwd in cesarean section. Half of participants received general anesthesia, while the other half received spinal anesthesia Electrocardiography…
- Trial name
- NCT03134677
- Testing
- Bupivacaine, Sevoflurane
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trakya University
Obstetric Anesthesia, Spinal Anesthesia
ED50 Determination of Hydroxyethylstarch for Treatment of Hypotension During Cesarean Section Under Spinal Anesthesia
The purpose of this trial is to determine the effective volume of hydroxyethylstarch 130/0.4 which would prevent the occurence of maternal hypotension in 50% of healthy pregnant women undergoing a cesarean section under spinal…
- Conditions
- Obstetric Anesthesia, Spinal Anesthesia, Hypotension, Fluid Therapy
- Trial name
- NCT01415284
- Testing
- Hydroxyethylstarch 130/0.4
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Spinal Anesthesia for Cesarean Section
Comparison of Fractionated Versus Bolus Administration of Different Doses of Hyperbaric Bupivacaine Combined With Opioids in Spinal Anesthesia for Caesarean Section
This study aimed to compare the effectiveness and safety of fractionated versus bolus administration of different doses of hyperbaric bupivacaine (0.06 and 0.07 mg/cm height) combined with opioids in spinal anesthesia for…
- Trial name
- NCT07249814
- Testing
- Fractionated anesthesia, Bolus anesthesia
- Where
- Ukraine
- Volunteers
- 99 people
- Sponsor
- Bogomolets National Medical University
Cesarean Section Complications, Hypotension
Continuous Infusion of Norepinephrine vs Phenylephrine During Spinal Anesthesia for Cesarean Section (INPEACE)
The goal of this clinical trial is to compare norepinephrine and ephedrine in maintaining blood pressure during spinal anaesthesia for elective cesarean delivery.
- Trial name
- INPEACE (NCT06248593)
- Testing
- Continuous infusion of Norepinephrine, Continuous infusion of Phenylephrine
- Where
- 2 sites in Morocco
- Volunteers
- 140 people
- Sponsor
- Hassan II University
General Anesthesia Versus Spinal Anesthesia on BNP Hormone Levels Preoperatively and Postoperatively in Parturient Cardiac Patient Undergoing C.S
Effect of Different Types of Anesthesia on Perioperative Brain Natriuretic Peptide Levels in Parturient Cardiac Patient Undergoing Elective Cesarean Section
comparing the effect of general anesthesia versus spinal anesthesia on brain natruretic peptide hormone levels preoperatively and postoperatively in parturient cardiac patient undergoing cesarean section
- Trial name
- NCT03460184
- Testing
- G.A Group A:
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post-operative Nausea and Vomiting
Effect of Using Azithromycin Versus Placebo With Dexamethasone in Prevention of Post-spinal Nausea and Vomiting.
Postoperative nausea and vomiting is defined as any nausea, retching, or vomiting occurring during the first 24-48 h after surgery in inpatients.
- Trial name
- NCT03165123
- Testing
- Oral Azithromycin tablet, Intravenous dexamethasone
- Volunteers
- 160 people
- Sponsor
- Assiut University
Cesarean Section, Anesthesia, General
Comparing Inhalational Anesthesia and TIVA on Maternal and Neonatal Hemodynamics in Elective Cesarean Section
This prospective, double-blind, randomized controlled trial compares the effects of total intravenous anesthesia (TIVA) versus sevoflurane-based inhalational anesthesia on maternal hemodynamics, depth of anesthesia, and early…
- Conditions
- Cesarean Section, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- NCT07513870
- Testing
- Propofol, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Medipol University
Well-Being, Psychological
The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During Routine Cesarean Delivery
This study aims to explore the experience that the patient has as they undergo a routine Cesarean Delivery (CD). The indication for undergoing a routine CD varies amongst patients, but usually there is either an obstetric or…
- Trial name
- PAS-EDU-RCD (NCT06368570)
- Testing
- Interview
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital