Clinical trials: Anesthesia for Cesarean Delivery
Pregnancy Related, Cesarean Section Complications
Predictive Hemodynamic Monitoring During Elective Cesarean Section
Single shot spinal anesthesia (SA) is the most commonly used technique for Caesarean section (CS) . SA is associated with maternal hypotension (Post Spinal Hypotension - PSH) often accompanied by nausea, vomiting, bradycardia and…
- Conditions
- Pregnancy Related, Cesarean Section Complications, Hypotension on Induction, Anesthesia Complication
- Trial name
- PREDICTION (NCT06729827)
- Testing
- Hypotension prediction Index - HPI
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cesarean Section
Development of a Risk Prediction Model for Post-Spinal Anesthesia Hypotension During Cesarean Delivery Using Heart Rate, Blood Pressure, Perfusion Index, ECG Waveforms, and SpO₂ Waveforms
Spinal anesthesia is the preferred anesthetic technique for patients undergoing cesarean section. Compared with general anesthesia, spinal anesthesia offers multiple advantages.
- Trial name
- NCT07689825
- Testing
- Standard clinical spinal anesthesia and routine intraoperative monitoring
- Where
- China
- Volunteers
- 145 people
- Sponsor
- Peking University Shenzhen Hospital
Cesarean Delivery, General Anesthesia
The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry
The SOAP registry is a prospective, multicenter, electronic registry. The goal is to investigate the indications, mode of airway management, predisposing factors, and obstetric and anesthetic outcomes of pregnant patients who…
- Trial name
- NCT06030063
- Where
- 35 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Yale University
Cesarean Section
Fluid Management for Cesarean Section
Cesarean section-associated hypotension is one of the pivotal factors to influence the Apgar Score of children and related with the stable hemostasis during the whole process of labor.
- Trial name
- FMCS (NCT00488111)
- Testing
- Ringer's Lactate, 6% Starch
- Where
- China
- Volunteers
- 850 people
- Sponsor
- Nanjing Medical University
Parturients, Elective Cesarean Delivery
Maternal Satisfaction After Spinal Anesthesia for Cesarean Delivery
The goal of this observational study is to evaluate the impact of four different spinal anesthesia regimens on maternal satisfaction following cesarean delivery.
- Trial name
- NCT07438171
- Testing
- Bupivacaine %0.5 (hyperbaric), Bupivacaine %0.5 (hyperbaric) and morphine, Bupivacaine %0.5 (hyperbaric), morphine and fentanyl 15
- Volunteers
- 200 people
- Sponsor
- University of Novi Sad
Respiratory Depression
Observation of Respiration Following Regional Anaesthesia With Intrathecal Opioids for Caesarean Section
Spinal Administration of opioids offers segmental analgesia, but has side effects including pruritus, nausea and vomiting, urinary retention, hypotension, and respiratory depression, both early and delayed.
- Trial name
- NCT00544947
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- NHS Greater Clyde and Glasgow
Pregnancy
Evaluation of Ultrasound (US) Assistance for Anesthesia Trainees for Caesarean Section Spinal Placement
Parturients receiving spinal anesthetic for Cesarean section will be randomized to have/not have pre-spinal ultrasound examination of their back.
- Trial name
- NCT01444638
- Testing
- Ultrasound examination
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Post-operative Pain
Intrathecal Morphine vs. Intrathecal Morphine and Regional Anesthesia After Cesarean Section.
The objective of the study is to optimize post-operative analgesia and improve patient satisfaction while reducing total opioid consumption after cesarean section
- Trial name
- NCT06114121
- Testing
- erector spinae plane block (ESP), Duramorph, Ropivacaine
- Sponsor
- University of Miami
Spinal Anesthesia, Cesarean Section
Predicting Spinal Hypotension in Cesarean Section
This prospective observational study investigates the predictive value of anthropometric and hemodynamic indices for spinal anesthesia-induced hypotension (SAIH) during cesarean section.
- Conditions
- Spinal Anesthesia, Cesarean Section, Hypotension
- Trial name
- prediction (NCT07499947)
- Where
- Turkey (Türkiye)
- Volunteers
- 321 people
- Sponsor
- TC Erciyes University
Morbid Obesity
Apneic Oxygenation for Morbid Obese Parturient in cs
The aim of this study is to compare the effect of apneic preoxygenation to conventional preoxygenation on the oxygen desaturation in morbid obese parturient performing elective caesarean section under general anesthesia.
- Trial name
- NCT05021549
- Testing
- nasal prong
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obstetric Anesthesia Problems
Evaluation of the Level of Oxidative Stress in Relation to the Type of Anesthesia in Parturients Whose Delivery Was Completed by Caesarean Section
The goal of this observational study is to assess the level of oxidative stress during cesarean section depending on the type of anesthesia applied and to determine the factors that can affect the level of oxidative stress.
- Trial name
- NCT05973435
- Testing
- Blood sampling
- Where
- Serbia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Clinic Dr Dragisa Misovic-Dedinje
Anesthesia, General, Anesthesia, Spinal
The Effect of General and Spinal Anesthesia on Neutrophil-to-lymphocyte Ratio
The aim of the study was to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV)…
- Conditions
- Anesthesia, General, Anesthesia, Spinal, Umbilical Cord
- Trial name
- NCT05409885
- Testing
- General anesthesia, Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Postoperative Pain
Adding Different Additives to Bupivacaine-fentanyl Mixture in Spinal Anesthesia for Cesarean Section
Spinal anesthesia is widely used in cesarean section, but it is associated with high incidence of side effects. To reduce the occurrence of side effects, intrathecal adjuvant was recommended to use in spinal anesthesia, with the…
- Trial name
- NCT04464616
- Testing
- spinal anaesthesia
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Caesarean Section, Spinal Anesthesia
Evaluating the Effectiveness of Ondansetron Versus Dexamethasone Versus Placebo for the Control of Intraoperative Nausea and Vomiting in Patients Undergoing Lower-segment Caesarean Section Under Spinal Anesthesia
The goal of this randomized controlled trial is to evaluate the effectiveness of Ondansetron, Dexamethasone, and Placebo for intraoperative nausea and vomiting in patients undergoing caesarian section under spinal anesthesia.
- Trial name
- ODP (NCT05583214)
- Testing
- Ondansetron 8mg, Dexamethasone 8mg, Normal saline
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muhammad Mubariz
Analgesia, Acute Pain
Comparison of the Effects of QLB 2 and QLB 3 on Post-operative Analgesia in Cesarean Section Surgery
This study evaluates the post-operative analgesic effects of quadratus lomborum block 2 and 3 (QLB 2, 3) in patients having cesarean section with spinal anesthesia.
- Conditions
- Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT04364906
- Testing
- Regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Hypotension, Obstetrical Complication of Anesthesia
Comparison of Norepinephrine and Ephedrine on Hypotension After Spinal Anesthesia in Parturients
Incidence of hypotension is high in parturients after spinal anesthesia. Ephedrine could be used to treat hypotension but lead to lower fetal pH as well.
- Conditions
- Hypotension, Obstetrical Complication of Anesthesia, Complications; Cesarean Section
- Trial name
- NCT02542748
- Testing
- Norepinephrine, Ephedrine
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Air Force Military Medical University, China
Cesarean Sections
Thoracic vs Lumbar Spinal Anesthesia for Cesarean Delivery
This randomized controlled trial aims to compare the effects of thoracic segmental spinal anesthesia and conventional lumbar spinal anesthesia on postoperative recovery in patients undergoing elective cesarean section.
- Trial name
- NCT07567612
- Testing
- Thoracic Segmental Spinal Anesthesia, Lumbar Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University Research Hospital
Intraoperative Nausea-retching-vomiting Episodes, Nausea Scores Will be Evaluated on the Verbal Analog Scale (VAS)
Antibiotic Prophylaxis and Nausea and Vomiting in Cesarean Section Under Regional Anesthesia.
The incidence of intraoperative nausea and vomiting in patients who undergo caesarean section (C/S) under regional anesthesia is approximately 30-80%.
- Trial name
- NCT04697277
- Testing
- Antibiotic prophylaxis timing (before skin incision and after cord clamping) for caesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Baskent University Ankara Hospital
Cesarean Delivery
Cesarean Anesthesia Blood Gas
This prospective observational cohort study will evaluate maternal and fetal blood gas parameters in women undergoing cesarean delivery under spinal or general anesthesia.
- Trial name
- NCT07861633
- Testing
- Anesthesia Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Bagcilar Training and Research Hospital