Clinical trials: Anesthesia for Cesarean Delivery
Complications; Cesarean Section, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Phenylephrine Dose and Mode of Administration for Spinal Anesthesia Induced Hypotension
Three different regimens of phenylephrine are being evaluated to see if one is superior over the other in the maintenance of cardiac output while keeping normotension and/or treating hypotension experienced when receiving spinal…
- Trial name
- NCT02101047
- Testing
- Phenylephrine
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Low Back Biomechanical Dysfunctions
Pain Pressure Threshold Values Versus the Biomechanical-Viscoelastic Findings of L4-5 Supraspinous Ligament in Women Who Underwent Cesarean Delivery With Spinal Anaesthesia
Cesarean delivery is a major obstetric surgery that aims to save the lives of mothers and their neonates from complications that may be related to high-risk pregnancy and difficult delivery (Teguete et al., 2012).
- Trial name
- NCT05367323
- Testing
- Pressure algometry (Baseline 2.2-Pound Dolorimeter) and Myoton PRO device (MyotonPRO; Myoton AS, Tallinn, Estonia)
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- South Valley University
Gestational Diabetes Mellitus (GDM), Obstetric Anesthesia
ULTRASOUND ASSESSMENT OF GASTRİC VOLUME IN PREGNANT WOMEN UNDERGOİNG ELECTİVE CESAREAN SECTİON, WITH AND WITHOUT GESTATİONAL DIABETES MELLITUS
THE PRIMARY OBJECTIVE OF THIS STUDY IS TO COMPARE GASTRIC VOLUME PRIOR TO ELECTIVE CESAREAN SECTION BETWEEN PREGNANT WOMEN DIAGNOSED WITH GESTATIONAL DIABETES MELLITUS (GDM) AND THOSE WITHOUT GDM.
- Trial name
- GDM (NCT07816705)
- Testing
- GASTRIC ULTRASONOGRAPHY
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Cesarean Section Complications
Effect of Three Weight-adjusted Vasopressors for Elective Cesarean Delivery
This study compared the effects of prophylactic infusion of metaraminol, phenylephrine and norepinephrine adjusted according to body weight on fetal acid-base balance and maternal hemodynamics.
- Trial name
- NCT04991662
- Testing
- metaraminol, Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Hemodynamics
Non-invasive vs Invasive Cardiac Output Monitoring During Cesarean Section
This study aims to evaluate the consistency of hemodynamic monitoring between NICAP and NICCO technologies (T20A; Chongqing, China) and the traditional pulse wave analysis method (EV1000; USA).
- Trial name
- NCT06473818
- Testing
- Non-invasive monitoring, Invasive monitoring
- Where
- China
- Volunteers
- 45 people
- Sponsor
- General Hospital of Ningxia Medical University
Hypotension Symptomatic, Obstetric Anesthesia Problems
Prevention of Hypotension During Cesarean Section
The aim of this double-blind randomized study will be to compare a fixed-rate prophylactic noradrenaline infusion to a fixed-rate prophylactic phenylephrine infusion during elective cesarean section under combined spinal-epidural…
- Conditions
- Hypotension Symptomatic, Obstetric Anesthesia Problems, Cesarean Section Complications, Vasoconstriction
- Trial name
- NOR-PHEN (NCT03842046)
- Testing
- phenylephrine infusion, norepinephrine infusion
- Where
- 2 sites in Greece
- Volunteers
- 82 people
- Sponsor
- Aretaieion University Hospital
Pain Levels
Dural Puncture Epidural Versus Epidural Anesthesia for Cesarean Delivery
This study will compare two anesthetics techniques called Dural Puncture Epidural (DPE) and Standard Epidural as to which of the two can provide faster and potentially better at providing pain relief for cesarean sections.
- Trial name
- NCT03915574
- Testing
- 25G Dural Puncture Epidural, Standard Epidural
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- University of Arkansas
Pregnancy Related
Pulmonary Echography and BNP Value Pre- and Post- Elective Cesarean Section in Spinal Anesthesia
Pregnancy is characterized by many biohumoral changes: circulation, respiratory mechanics, oncotic pressure, vascular permeability and many other systems are affected.
- Trial name
- NCT03851679
- Testing
- B-Type natriuretic peptide (BNP) serum values, Pulmonary echography, urine collection
- Volunteers
- 80 people
- Sponsor
- University of Udine
Post Operative Pain
The Safety and Efficacy of Surgical Rectus Sheath Block for Postoperative Analgesia After Elective Cesarean Delivery
All participants will receive spinal anaesthesia and will be randomly divided into 2 equal groups. In Group 1, 20 ml of local anesthetic solution will be administered bilaterally to the rectus sheath space under direct vision…
- Trial name
- NCT06020196
- Testing
- surgical rectus sheath block, subdermal local anaesthetic infiltration
- Where
- Egypt
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ahmed M Maged, MD
Obstetric Anesthesia Problems
Evaluation of the Level of Oxidative Stress in Relation to the Type of Anesthesia in Parturients Whose Delivery Was Completed by Caesarean Section
The goal of this observational study is to assess the level of oxidative stress during cesarean section depending on the type of anesthesia applied and to determine the factors that can affect the level of oxidative stress.
- Trial name
- NCT05973435
- Testing
- Blood sampling
- Where
- Serbia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Clinic Dr Dragisa Misovic-Dedinje
Epidural Anesthesia, Spinal Ultrasound
Ultrasound Versus Palpation for Epidural Catheterization
The study will assess the benefit of using spinal ultrasound before epidural catheter insertion compared to the conventional palpation technique in women undergoing cesarean section.
- Trial name
- NCT02410226
- Testing
- Double-space combined spinal-epidural anesthesia, Preprocedure spinal ultrasound
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Anesthesia, Obstetrical, Anesthesia, Spinal
Phenylephrine and Hypotension During Spinal Anesthesia for Cesarean Section
Pregnant women with a positive preoperative Supine stress test were found to be a subgroup at increased risk of symptomatic hypotension after spinal anesthesia
- Trial name
- NCT02958215
- Testing
- Phenylephrine
- Where
- Egypt
- Volunteers
- 980 people
- Sponsor
- Assiut University
Hypotension, Pregnancy
ET50 With Fentanyl for Post Caesarean Section Spinal Hypotension
Hypotension is extremely common after induction of spinal anesthesia for cesarean delivery. Anesthetic blockade of the sympathetic outflow of the spinal cord causes vasodilation, and is one cause of this hypotension.
- Trial name
- ET-50-Fent (NCT01896960)
- Testing
- Bupivacaine with 15 micrograms of fentanyl
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pain, Postoperative
The Effect of IV Dexamethasone on the Duration of Analgesia of Spinal Anaesthesia for C-Sections at a Jamaican Hospital
Dexamethasone is one of many adjuncts tested to prolong the duration of spinal anesthesia and its analgesic effect. The intent of this, a single-site, double-blinded, randomized controlled trial, is to determine if a single…
- Trial name
- NCT04624360
- Testing
- Dexamethasone
- Where
- Jamaica
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Hypotension
Up-Down Determination of the ED90 of Metaraminol to Treat Hypotension During Cesarean Section
The purpose of this study is to find the best dose of metaraminol to be used in patients during elective cesarean sections.
- Trial name
- NCT01108874
- Testing
- Metaraminol
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cardiac Output, Hypotension
Cardiac Output Changes During Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Cesarean Section
Spinal block leads to the reduction of systemic vascular resistance (SVR) which may effect the cardiac output. Ngan Kee et al. has showed that spina block with 0.5% hyperbaric bupivacaine for Cesarean section combined with…
- Conditions
- Cardiac Output, Hypotension, Anesthesia, Spinal
- Trial name
- NCT02737813
- Testing
- Isobaric marcaine, Hyperbaric marcaine
- Where
- Thailand
- Volunteers
- 168 people
- Sponsor
- Mahidol University
Cesarean Section, Transversus Abdominis Plane (TAP) Block
The Effect of TAP Block on Maternal-Infant Bonding
Cesarean delivery is a common surgical procedure that is typically performed under spinal anesthesia. Postoperative pain management has a significant impact on both the mother's physical recovery and the quality of…
- Trial name
- NCT06858891
- Testing
- Transversus abdominis plane (TAP) block
- Volunteers
- 132 people
- Sponsor
- Adiyaman University Research Hospital
Spinal Anesthesia, Cesarean Section
The Role of Carotid Flow Time-Based Fluid Administration in Caesarean Section
It has been reported that corrected carotid flow time (FTc) may indicate the responsiveness of spontaneously breathing patients to fluid therapy.
- Trial name
- NCT06048497
- Testing
- Corrected carotid flow time measurement guided fluid preload
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Cukurova University
Spinal Anesthesia Induced Hypotension, Caeserian Section
AI Prediction of Post-Induction Hypotension in Cesarean Sections With Spinal Anesthesia
The cesarean section, medically necessary for both the mother and the baby in certain cases, is a life-saving operation.The most commonly used anesthesia method worldwide is spinal anesthesia.
- Trial name
- NCT06158542
- Testing
- Spinal Anesthesia, Blood Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 370 people
- Sponsor
- Hacettepe University
Post-spinal Shivering
Prophylactic Tramadol Versus Magnesium Sulphate for Prevention of Post-Spinal Shivering
This randomized controlled trial compared prophylactic intravenous tramadol and magnesium sulphate for the prevention of post-spinal shivering among women undergoing elective cesarean section under spinal anesthesia.
- Trial name
- TRAM-MAGS (NCT07838662)
- Testing
- Tramadol, Magnesium Sulphate
- Where
- Pakistan
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Punjab Rangers Teaching Hospital Lahore