Clinical trials: Anesthesia for Cesarean Delivery
Cesarean Section, Dexamethasone
Intravenous Dexamethasone Effectiveness in Post Caesarean Section Analgesia
The management of postpartum pain is essential to ensure early rehabilitation for parturients. Intravenous dexamethasone has a potent analgesic action when used in the context of general anesthesia.
- Conditions
- Cesarean Section, Dexamethasone, Postoperative Pain, Spinal Anesthesia
- Trial name
- NCT05535036
- Testing
- Dexamethasone 4mg
- Where
- Tunisia
- Volunteers
- 84 people
- Sponsor
- Mongi Slim Hospital
Anesthesia, Spinal and Epidural, Adverse Effect
Intravenous Bolus of Phenylephrine vs. Norepinephrine in Preventing Hypotension After Spinal Anesthesia
The purpose of the study is to determine if an intravenous bolus of phenylephrine is more effective compared to an intravenous bolus of norepinephrine associated with crystalloid loading for maintaining blood pressure during a…
- Conditions
- Anesthesia, Spinal and Epidural, Adverse Effect, Hypotension, Complications, Cesarean Section
- Trial name
- NorPN (NCT02854787)
- Testing
- Phenylephrine, Norepinephrine
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Cesarean Section, Anesthesia, Spinal
Comparison of Standard and Minidose Spinal Anesthesia for Cesarean Section Operation Using Marcaine Spinal 0.5% Heavy
The objectives of this study is to test a combination of low dose local anesthetic Bupivacaine diluted in patient's CSF with lipophilic opiate Fentanyl for optimal spinal anesthesia during Cesarean Section.
- Conditions
- Cesarean Section, Anesthesia, Spinal, Local Anaesthetics Causing Adverse Effects in Therapeutic Use
- Trial name
- NCT01303731
- Testing
- Bupivacaine and Fentanyl, Bupivacaine
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Emetic Attacks During Caesarean Delivery With Spinal Anesthesia
Comparison Between Drugs for Control of Emetic Attacks During Caesarean Delivery
Single shot spinal anesthesia is widely used for most surgical operations especially in obstetric such as hysterectomy, tubal ligation after vaginal delivery, cesarean and curettage etc.; however, in general, cesarean is…
- Trial name
- NCT06300346
- Testing
- Propofol
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hypotension, Anesthesia
Intramuscular Phenylephrine HCL for Prevention of Spinal Anesthesia Induced Hypotension
Background: Spinal anesthesia (SA) is preferred over general anesthesia in Cesarean section (CS) due to its better safety profile but SA induced hypotension remains a big challenge for the clinical Anesthetist.
- Trial name
- NCT05348980
- Testing
- Phenylephrine Hydrochloride 4 mg, Phenylephrine Hydrochloride 8 mg
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
Post-Surgical Complication
Comparsion of IV Dexmedetomidine, Tramdol and Ketamine for Post Spinal Anesthesia Shivering.
To study control of post spinal shivering in patients undergoing lower segment cesarean section using dexmedetomidine, tramadol and ketamine
- Trial name
- NCT05311722
- Testing
- Dexmedetomidine, Ketamine, Tramadol
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Medical College
Effects of Anesthesia Spinal and Epidural in Pregnancy
The Relationship Between Perfusion Index and Pleth Variability Index and Hemodynamics in Spinal Anesthesia
In routine practice, the preferred anesthesia method in cesarean section operations is spinal anesthesia, but it causes hypotension in a significant part of the patients.
- Trial name
- NCT05174260
- Testing
- perfusion index, pleth variable index
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Adiyaman University
Caesarean Delivery, Hypotension Postprocedural
Comparison of Classic and Sequential Spinal Techniques for Preventing Hypotension During Cesarean Delivery.
Given the clinical importance of maternal hypotension, the potential advantages of sequential spinal dosing warrant formal evaluation in a prospective, adequately powered randomized controlled trial.
- Trial name
- NCT07327866
- Testing
- Classic group, Sequential group
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Al-Azhar University
Anesthesia; Adverse Effect, Spinal and Epidural, Headache, Complications; Anesthesia, Spinal and Epidural, in Pregnancy
Comparison of Two Spinal Needles Regarding Postdural Puncture Headache
The aim of the study is to observe the rate of postdural puncture headache observed after spinal anesthesia in cesarean section patients. Two kind of spinal anesthesia needles will be used: 1.
- Trial name
- NCT01821807
- Where
- Turkey (Türkiye)
- Volunteers
- 256 people
- Sponsor
- Adiyaman University Research Hospital
Cesarean Section Complications
Vasopressor Prophylaxis After Spinal Anesthesia
Norepinephrine has been recently introduced as a prophylactic vasopressor during Cesarean delivery with promising results ; However, the optimum dose for efficient prophylaxis with the least side effects is not known.
- Trial name
- NCT03234816
- Testing
- Norepinephrine 0.05 mcg /Kg/min, Norepinephrine 0.1 mcg /Kg/min, Norepinephrine 0.15 mcg /Kg/min
- Where
- Egypt
- Volunteers
- 270 people
- Sponsor
- Cairo University
Patient Reported Outcome Measures, Quality of Recovery
Translation and Validation of the Turkish Version of the ObsQoR-11 Questionnaire
Ciechanowicz et al. developed and validated a postpartum recovery score for women with a caesarean section: the ObsQoR-11. The psychometric validation of the ObsQoR-11 confirms its reliability, its response to change, its…
- Conditions
- Patient Reported Outcome Measures, Quality of Recovery, Cesarean Section, General Anesthesia
- Trial name
- ObsQoR-11T (NCT04744311)
- Testing
- ObsQoR-11T Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Anesthesia, Perinatal Morbidity
General Anesthesia for Cesarean Section, Maternal and Perinatal Outcomes
To evaluate the maternal and perinatal outcomes that occur in obstetric patients undergoing cesarean section surgery under general anesthesia at the Fray Antonio Alcalde Civil Hospital of Guadalajara.
- Conditions
- Anesthesia, Perinatal Morbidity, Maternal-Fetal Relations
- Trial name
- NCT06160583
- Where
- Mexico
- Volunteers
- 5,000 people
- Sponsor
- Hospital Civil de Guadalajara
Anxiety, Stress (Psychology)
Cellphone Access for Lowered Maternal Anxiety and Stress in Cesarean Sections
This study looks at whether allowing mothers to use their personal cellphone during a planned cesarean section (C-section) under spinal anesthesia can reduce stress and anxiety and improve their overall birth experience.
- Trial name
- CALMAS-CS (NCT07759726)
- Testing
- Cell Phone Use
- Where
- Lebanon
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Postoperative Pain, Caesarean Section
Intraperitoneal Hydrocortisone for Postoperative Pain and CRP Following Caesarean Section
The purpose of this study is to evaluate the clinical efficacy of intraperitoneal hydrocortisone 100 mg administration in reducing postoperative pain and inflammatory response in patients undergoing elective Caesarean section…
- Conditions
- Postoperative Pain, Caesarean Section, Peritoneal Inflammation
- Trial name
- NCT07892547
- Testing
- hydrocortisone, Nornal Saline
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Raditsya Mada Gautama, MD
Anesthesia, Spinal, Cesarean Section
Post Spinal Anesthesia Hypotension and Preoperative Hydration
Study of the impact of preoperative oral rehydration on the incidence of spinal anesthesia-induced hypotension for scheduled cesarean section.
- Trial name
- NCT04450667
- Testing
- Nutricia PreOp
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Postoperative Pain
Intravenous Ketamine and Postoperative Pain Following Cesarean Section.
The purpose of this study is to investigate the analgesic effect of low-dose intravenous ketamine in pregnant mothers undergoing cesarean section under Bupivacaine spinal anesthesia.
- Trial name
- NCT03018301
- Testing
- Ketamine, Normal saline
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Preeclampsia
Ephedrine, Phenylephrine and Metaraminol Effects on Maternal Cardiac Output, Uterine Blood Flow and Fetal Circulation
It is a prospective clinical trial with random distribution that intends to investigate maternal and fetal effects of ephedrine, phenylephrine and metaraminol during cesarean delivery in patients with pre-eclampsia.
- Trial name
- NCT02245191
- Testing
- Ephedrine, Phenylephrine, Metaraminol
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Incidence of Post-spinal Hypotension
Norepinephrine With Ephedrine Versus Norepinephrine Alone During Spinal Anesthesia for Cesarean Delivery
We hypothesize that the addition of ephedrine to norepinephrine infusion could decrease the incidence of post spinal hypotension(PSH) in parturient undergoing C.S under spinal anesthesia and minimize the changes in heart rate
- Trial name
- NCT07379710
- Testing
- Ephedrine and Norepinephrine infusion, Norepinephrine infusion
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Cairo University
Shivering, Spinal Anesthesia
Use of Iv Tramadol and Ketamine for Prevention of Post Spinal Anesthesia Shivering
*Ketamine:* Ketamine is a medication that can help reduce shivering by blocking certain nerve signals in the brain. It's like a "nerve blocker" that helps calm down the body's shivering response.
- Trial name
- NCT06722742
- Testing
- Ketamine only, Tramadol
- Where
- 3 sites in Pakistan
- Volunteers
- 250 people
- Sponsor
- Liaquat National Hospital & Medical College
Cesarean Section, Pregnancy
Intra-abdominal Pressure, Abdominal Circumference, and Spinal Block Level in Cesarean Section
Spinal anesthesia is commonly used for cesarean section and provides effective anesthesia with rapid onset. However, the spread of spinal anesthesia may vary among pregnant women due to physiological and anatomical changes during…
- Conditions
- Cesarean Section, Pregnancy, Elective Cesarean Section
- Trial name
- NCT07406373
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Kutahya Health Sciences University