Clinical trials: Anesthetic, Inhalation
Anesthesia, General
Effect of Binaural Beats for Maintenance of General Anesthesia
The goal of this clinical trial is to learn about the effects of binaural beats on maintenance of general anesthesia in patients undergoing thyroidectomy without intraoperative neuromonitoring.
- Trial name
- BB (NCT06002568)
- Testing
- Silent, Binaural beats
- Where
- South Korea
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Pharmacokinetics of Inhaled Anesthetics
Ventilatory Effect on Speed of Anesthesia Under Various Inhaled Anesthetics
Three groups of patients are going to have minor surgery under general anesthesia with inhaled anesthetics and different ventilatory setting (Tidal volume: 8, 10, 12 ml/kg, respiratory rate: 10/min each).
- Trial name
- NCT01171833
- Testing
- Sevoflurane, Desflurane, Isoflurane
- Volunteers
- 36 people
- Sponsor
- DongGuk University
Elective Surgical Procedures, Laparoscopy
Nitrous Oxide Added at the End of Sevoflurane Anesthesia and Recovery
Addition of nitrous oxide N2O towards the end of prolonged isoflurane anesthesia hastens patients recovery. The hypothesis is that the addition of N2O at the end of prolonged sevoflurane anaesthesia also hastens early recovery…
- Conditions
- Elective Surgical Procedures, Laparoscopy, Laparotomy, Anesthesia, General
- Trial name
- SEVONATE (NCT03420586)
- Testing
- Nitrous Oxide
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- General Hospital Zadar
Liver Function After Partial Liver Resection
Xenon-anesthesia on Patients Undergoing Major Liver-resection
The aim of this study is to compare the postoperative outcome of patients undergoing major liver resection under xenon- compared to desflurane-anesthesia.
- Trial name
- XeLiv (NCT03504033)
- Testing
- Xenon, Desflurane
- Where
- Germany
- Sponsor
- RWTH Aachen University
Scrotum Disease, Hydrocele Male
Efficacy of Inhaled Methoxyflurane (Penthrox) as Adjunct for Urologic Procedures Under Local Anesthetic: A Pilot Study
We wish to perform a prospective randomized controlled pilot study at the Men's Health Clinic and Health Science's Centre to assess whether or not the use of Penthrox as an adjunct to LA is associated with improved pain tolerance…
- Conditions
- Scrotum Disease, Hydrocele Male, Spermatocele, Scrotal Hematocele
- Trial name
- NCT07192198
- Testing
- Methoxyflurane, Control
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Endotracheal Intubation, Deep Sedation
Inhaled Sedation Using the Anesthetic-conserving Device ( ANACONDA) in Prehospital Emergency Medecine.
Achieving the optimal sedation level for patient management is not always possible using our standard intravenous medications in Pre-hospital Emergency medicine.
- Trial name
- ANACONDA (NCT04141267)
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Anesthetics, Inhalation
Blood Levels of Sevoflurane and Desflurane
16 patients with American Society of AnesthesioIogy (ASA) physical status I-III will recruited to this study. Patients will divided to the 2 groups. %1.5 Sevoflurane will apply in Group S and %6 Desflurane will apply in Group D.
- Trial name
- NCT03015350
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Cukurova University
Colorectal Cancer Metastatic, Survival Rate
The Effects of General Anesthetics on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and Mechanism Involved
The body immunity is important to the development of tumor. The immune system is in charge of monitoring and cleaning tumor cells in circulation. Anesthesia may alter the immune response and affect the elimination of tumor cells.
- Conditions
- Colorectal Cancer Metastatic, Survival Rate, General Anesthetics Toxicity, Lymphocyte Destruction
- Trial name
- NCT03193710
- Testing
- Propofol, Sevoflurane, Remifentanil
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Guizhi Du
ASA Class I/II Patients, General Anesthetic
PCV vs VCV in Low-Flow Anesthesia
The aim of this observational study is to investigate the effects of ventilation modes on intraoperative and postoperative lung functions in patients under general anesthesia.
- Conditions
- ASA Class I/II Patients, General Anesthetic, Low Flow Anesthesia
- Trial name
- NCT07305129
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- HULYA TOPCU, MD
Sore Throat
Inhalation of Lidocaine Before Intubation
We investigate the potential benefits of ultrasound-driven lidocaine inhalation immediately before induction.
- Trial name
- NCT01838993
- Testing
- Lidocaine inhalation
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- New Taipei City Hospital
Oxidative Stress, Cardiac Surgery
The Comparison of Oxidative Stress Between Inhalation Anesthetics
Oxidative stress is an unavoidable event during cardiac surgery. Isoprostanes have been demonstrated to be a reliable biomarker for the evaluation of oxidative stress in vivo.The aims of this study are(1)to develop an accurate…
- Trial name
- NCT00965445
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Exposure to Environmental Pollution, Adverse Effect of Unspecified General Anesthetic
Anesthetic Gas Leakage in Children During Tonsillectomy: a Comparison of Cuffed and Uncuffed Tracheal Tubes
Fires and operating room pollution may occur when anesthesia gases leak into the oropharynx during airway surgery. Investigators sought to measure the concentrations of anesthetic gases that leak into the mouth of children…
- Trial name
- NCT02725164
- Testing
- oxygen concentration, nitrous oxide concentration, carbon dioxide concentration
- Volunteers
- 31 people
- Sponsor
- State University of New York at Buffalo
Intraoperative Hypotension
Bispectral Index Guided Sevoflurane Titration
Electroencephalographic-based monitoring systems such as the bispectral index (BIS) may reduce anaesthetic overdose rates. The investigators hypothesised that goal-directed sevoflurane administration (guided by BIS monitoring)…
- Trial name
- NCT02515019
- Testing
- Bispectral index Monitoring
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Intensive Care Ventilation
Pressure Support Ventilation With the Anesthetic Conserving Device
Sevoflurane inhalational anesthetic has got pulmonary effects such as bronchodilatation. These effects could be of interest in intensive care patients ventilated in pressure support ventilation mode.
- Trial name
- NCT01017744
- Testing
- Anesthetic Conserving Device
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Clermont-Ferrand
Lung Diseases, Total Intravenous Anesthesia
Effects of Adding Different Drugs for Preventing Cough Induced by Bronchoscopic Spraying of Local Anesthetics
Cough is the most unwanted response during bronchoscopic interventions for hemodynamic instability, hypoxemia, and interruption of interventions.
- Conditions
- Lung Diseases, Total Intravenous Anesthesia, Bronchoscopic Interventions
- Trial name
- NCT05072236
- Testing
- bronchoscopic insertion
- Where
- Taiwan
- Volunteers
- 108 people
- Sponsor
- National Taiwan University Hospital
Oxidative Stress, Morbid Obesity
A Comparison of the Effects of Desflurane and TIVA on Antioxidant System in Morbidly Obese Patients
With the development of technology, the safety of anesthesia devices and the progression of monitoring techniques affect the anesthetic management.
- Trial name
- OxSys (NCT03814577)
- Testing
- Total Antioxidant Status, Total Oxidant Status, Bispectral Index
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Inonu University
Lung Cancer, Progression, Disease
The Effects of Using Different Anesthetics on the Prognosis of Primary Lung Tumors and Its Mechanism of Action
This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary early lung cancer.
- Conditions
- Lung Cancer, Progression, Disease, Anesthesia
- Trial name
- NCT05663242
- Testing
- Propofol, Sevoflurane
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Airway Reflexes, Protective, Recovery After Neuromuscular Block
Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block
Protective airway reflexes may be impaired in the postoperative period, creating the potential for aspiration of gastric contents, even after a patient exhibits appropriate response to command.
- Conditions
- Airway Reflexes, Protective, Recovery After Neuromuscular Block, Anesthetic Recovery
- Trial name
- NCT01199237
- Testing
- Sevoflurane, Desflurane, Rocuronium
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- University of California, San Francisco
DNA Damage
The Effect of Desfluran On Global Dna Methylation
The purpose of this study is to demonstrate the molecular effect of desflurane on DNA by measuring the global DNA methylation level in patients under going lumbar spinal stenosis surgery under general anesthesia.
- Trial name
- NCT05111717
- Testing
- Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Muğla Sıtkı Koçman University
General Anesthesia, Children
Effects of Binaural Beats on Inhaled Anesthetic Requirements During General Anesthesia in Pediatric Patients
The hypothesis of this study is that continuously delivering binaural beats with a phase difference corresponding to the slow-delta frequency band during anesthesia in pediatric patients can clinically and significantly reduce…
- Trial name
- NCT06979206
- Testing
- Application of Binarual Beat
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital