Clinical trials: Anesthetics
Needlestick Injuries
The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic
The aim of the study is to find a simple method for pain reduction that can be used in clinical practice when administering digital nerve block with a single subcutaneous injection.
- Trial name
- NCT02086292
- Testing
- 2 ml 1% Lidocaine, 1 ml 2% Lidocaine
- Where
- Norway
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Mastectomy, Postoperative Pain
Comparison of Postoperative Analgesic Effectiveness of Superficial and Deep Serratus Plane Blocks for Mastectomy
Pain after breast surgery can be quite severe and can significantly affect quality of life. By successfully treating acute pain, it is aimed to prevent the formation of pain memory and to ensure that chronic pain never occurs.
- Conditions
- Mastectomy, Postoperative Pain, Analgesia
- Trial name
- NCT06438211
- Testing
- superficial or deep serratus anterior plane block for mastectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- TC Erciyes University
Colonic Diseases, Functional
Adequacy of Anaesthesia for Colonoscopic Procedures
The aim of this randomized prospective trial is to assess the utility of Adequacy of Anaesthesia technique (Response Entropy and Surgical Pleth Index) for monitoring pain perception intraoperatively and its influence on…
- Trial name
- AoAColon (NCT03922815)
- Testing
- rescue fentanyl, rescue propofol
- Where
- Poland
- Volunteers
- 158 people
- Sponsor
- Medical University of Silesia
Pain
Continuous Femoral Nerve Block Following Total Knee Replacement
The purpose of this study is to determine if putting local anesthetic-or numbing medication-through a tiny tube next to the nerves that go to the knee will improve pain control during physical therapy, and ultimately improve the…
- Trial name
- NCT00135889
- Testing
- Femoral perineural infusion
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Music Therapy, Perioperative Care
Effect of Music in Intraoperative Period
Background and Aims: Music therapy has a wide range of uses in health care practice. The aim of this study was to investigate the effects of intraoperative music played during spinal anesthesia operation on the patients'…
- Conditions
- Music Therapy, Perioperative Care, Postoperative Pain, Anxiety
- Trial name
- NCT04485650
- Testing
- music therapy, sedated group, non-sedated group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Abant Izzet Baysal University
Pain
Local Infiltration Analgesia for Hip Arthroscopy
The purpose of this study is to examine if ultrasound guided infiltration of local anesthetic solution around the hip joint will provide effective pain control after hip arthroscopy.
- Trial name
- NCT01454518
- Testing
- Infiltration of local anesthetic, Normal Saline Injection
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Trinity Health Of New England
Breast Cancer
Anesthetic Effect on Immune Cell in Patients With Cancer
Anesthetics agents has an effect on immune response during the cancer surgery.This influence can regulatory to immune activity or cancer cell survival.
- Trial name
- NCT02758249
- Testing
- Sevoflurane, propofol
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Konkuk University Medical Center
Anesthesia
Effect of Gender on Propofol Requirement
Total intravenous anaesthesia (TIVA) has emerged as a viable alternative to inhalational general anaesthesia (GA). Propofol is the preferred drug for providing TIVA due to its favorable pharmacokinetic profile, such as, rapid…
- Trial name
- NCT05725135
- Testing
- Propofol
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Sir Ganga Ram Hospital
Oropharyngeal Microbiology
Probiotics Against Pathogenic Bacteria in Connection With Anaesthesia
Longer surgical procedures require intubation and there is a potential risk of contaminating the lower airways with pathogenic bacteria from the mouth and oropharynx.
- Trial name
- NCT01521650
- Testing
- Probiotics
- Where
- Sweden
- Volunteers
- 42 people
- Sponsor
- Region Skane
Tibial Plateau Fractures
Local Anesthetic for Plateau Fractures
Subjects may receive an injection at the end of the surgery to fix their broken leg that may reduce their pain and hospital stay
- Trial name
- NCT06474949
- Testing
- Bupivacaine injection, Saline
- Volunteers
- 100 people
- Sponsor
- University of Washington
Obstetric Anesthesia Care
Obstetric Anaesthesia And Analgesia Month Attributes - in COVID-19
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia and to evaluate the impact of COVID-19 pandemic on obstetric anesthesia and analgesia in Czech Republic and…
- Trial name
- OBAAMA-COV (NCT04912791)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 5,000 people
- Sponsor
- Brno University Hospital
Anesthesia, General, Anesthesia, Endotracheal
Comparison of Carotid Peak Systolic Velocity Variation With Aortic Peak Systolic Velocity Variation in Pediatric Non-Cardiac Surgery
The purpose of this study is to evaluate whether carotid Doppler peak systolic velocity can be an easy to measure possible surrogate for echocardiographic measurement of aortic peak systolic velocity variation which is an index…
- Conditions
- Anesthesia, General, Anesthesia, Endotracheal, Mechanical Ventilation, Fluid Responsiveness
- Trial name
- NCT03155555
- Testing
- Measurement of aortic and carotid Doppler peak systolic velocity variation
- Where
- India
- Volunteers
- 52 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Ultrasound, Needle
Ultrasound-guided Non-invasive Simulation in Anesthesia Residency Training
Study Aim: This trial evaluates if a novel non-invasive, AI-assisted simulation training improves ultrasound-guided needle visualization skills in anesthesia residents.
- Conditions
- Ultrasound, Needle, Residency, Anesthesiology
- Trial name
- non-invasive (NCT07385885)
- Testing
- Non-invasive Simulated Puncture Teaching Group
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Chronic Shoulder Pain, Shoulder Impingement Syndrome
Ultrasound-Guided Suprascapular Nerve RFA vs Steroid-Local Anesthetic Injection in Chronic Shoulder Pain
This study aims to compare the clinical effectiveness of two interventional treatments for chronic shoulder pain related to suprascapular nerve pathology: ultrasound-guided suprascapular nerve block and suprascapular nerve…
- Conditions
- Chronic Shoulder Pain, Shoulder Impingement Syndrome, Rotator Cuff-Related Shoulder Pain, Suprascapular Nerve-Related Shoulder Pain
- Trial name
- NCT07302490
- Testing
- Pulsed Radiofrequency (PRF) of the Suprascapular Nerve, Suprascapular Nerve Block with Local Anesthetic and Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Nida Koçer Nazlıgül
Postoperative Pain
Single Dose Pharmacokinetics and Pharmacodynamics of Bupivacaine Following Transversus Abdominis Plane (TAP) Block in Neonates
This study is being done to try to learn more about how a child's body breaks down bupivacaine, a local anesthetic medication that is being used for pain control.
- Trial name
- NCT01557985
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Hypotension, Anesthesia
Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Patient undergoing general anesthesia in elective surgery will be assigned to receive either methohexital or propofol general anesthesia.
- Trial name
- NCT02624050
- Testing
- Methohexital, Propofol
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Dermatochalasis of Upper Eyelid, Blepharoplasty
Perioperative Haemostasis, Procedure-Related Pain After Physiological or Pharmacological Modifications of Local Anaesthesia Around the Eyes
The goal of this clinical trial is to determine whether buffering, warming, or addition of hyaluronidase or tranexamic acid to lignocaine during eyelid injection of local anaesthesia reduce injection pain and procedure-related…
- Trial name
- P4LE (NCT07734740)
- Testing
- Sodium Bicarbonate (NaHCO3), Warmed lignocaine, Hyaluronidase Injection
- Where
- 3 sites in Hong Kong
- Volunteers
- 80 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Post Operative Pain, Anesthesia
Dexmedetomidine and Dexamethasone Added as Adjuvant Infraclavicular Brachial Plexus Block in Upper Limb Surgery
The aim of this study was to investigate the effect of dexmedetomidine and dexamethasone added during USG-guided infraclavicular block on block onset time, total block time and time to first analgesic need in patients undergoing…
- Conditions
- Post Operative Pain, Anesthesia, Acute Pain
- Trial name
- NCT06779604
- Testing
- Infraclavicular Block with Dexmedetomidine and Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Umraniye Education and Research Hospital
Health Information Technology
Anesthesiology Control Tower
This study is a pragmatic, comparative effectiveness trial that will randomize approximately 12,000 adult surgical patients on an operating room (OR) level to a control or to an intervention group.
- Trial name
- ACTFAST (NCT02830126)
- Testing
- Anesthesiology Control Tower Feedback
- Where
- United States
- Volunteers
- 15,158 people
- Sponsor
- Washington University School of Medicine
Hot Flashes, Menopause
Pilot Study of Stellate Ganglion Injection to Provide Relief From Hot Flushes
This study is being done to determine whether stellate ganglion injection with local anesthetic (the study procedure) can reduce the number and severity of hot flashes in women who have hot flashes.
- Trial name
- NCT00992914
- Testing
- Sympathetic nerve block with 1% lidocaine 1-2 ml, Superficial subcutaneous injection
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwestern University
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