Clinical trials: Aneurysm Dissecting
Spontaneous Coronary Artery Dissection, SCAD
Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)
The purpose of the research is to identify mutations (defects in the genetic blueprint) that cause spontaneous coronary artery dissection (SCAD), in other words, spontaneous tears in blood vessels that supply the heart.
- Trial name
- NCT01427179
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Fibromuscular Dysplasia, Spontaneous Coronary Artery Dissection
Defining the Basis of Fibromuscular Dysplasia (FMD)
The purpose of this study has evolved and expanded since its inception. Originally the intent was to establish the functional, molecular and genetic profile of fibroblasts from Fibromuscular Dysplasia (FMD) patients as compared…
- Conditions
- Fibromuscular Dysplasia, Spontaneous Coronary Artery Dissection, Cervical Artery Dissection
- Trial name
- DEFINE (NCT01967511)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Vertebral Artery Dissection, Traumatic, Neck Pain
Effects of Spinal Manipulation on Vertebrobasilar and Internal Carotis Arteries in Healthy Population
After lumbar pain, neck pain is the most common cause of patients needing chiropractic care; the second most common cause of spinal manipulation use (1).
- Trial name
- NCT03435159
- Testing
- Doppler Ultrasonography, Manual Chiropractic Spinal Manipulation, Instrumental Chiropractic Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Aortic Aneurysm, Thoracic, Aneurysm, Dissecting
A Registry Study on Genetics and Biomarkers of Thoracic Aortic Aneurysm/Dissection
This is a national registry study to determine genetic risk factor and serial biomarkers of thoracic aortic aneurysm/dissection
- Trial name
- ARSGBTAAD (NCT03010514)
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Connective Tissue Disease, Dissecting Aneurysm
Study of Heritable Connective Tissue Disorders
The purposes of this study are to identify the genes responsible for inherited connective tissue disorders and learn about the range of medical problems they cause.
- Conditions
- Connective Tissue Disease, Dissecting Aneurysm, Ehlers Danlos Syndrome, Marfan Syndrome
- Trial name
- NCT00001641
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Aneurysm Dissecting
Gender-related Differences in Chinese Patients With AAD
Few data exist on gender-related differences in clinical features, management, and outcomes of acute aortic dissection (AAD) in China.
- Trial name
- NCT02200835
- Volunteers
- 2,015 people, healthy volunteers welcome
- Sponsor
- General Hospital of Beijing PLA Military Region
Spontaneous Coronary Artery Dissection
Genetics of Spontaneous Coronary Artery Dissection (SCAD-INSPIRE Genetics)
Spontaneous coronary artery dissection (SCAD) is a rare cause of coronary ischemia and infarction where a tear in blood vessel wall either restricts the flow of blood or the blood becomes trapped in between the layers of the…
- Trial name
- SCAD-INSPIRE (NCT03876847)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Spontaneous Coronary Artery Dissection
A Study of SCAD Using Stress Contrast Echocardiography
This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contrast echocardiography.
- Trial name
- NCT07178509
- Testing
- Stress Echocardiography with Contrast
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Fibromuscular Dysplasia of Arteries, Segmental Arterial Mediolysis
Using Ultrasonography, Shear Wave Elastography, Strain Imaging, and 3-D Volume Ultrasonography on Cardiovascular Disease
The researchers are trying to see whether contrast-enhanced ultrasonography, shear wave elastography, strain imaging, and 3-D volume ultrasonography improves arterial wall visualization and identifies arterial elastic properties…
- Conditions
- Fibromuscular Dysplasia of Arteries, Segmental Arterial Mediolysis, Spontaneous Coronary Artery Dissection, Atherosclerosis of Artery
- Trial name
- NCT03335020
- Testing
- Shear Wave Elastography, Pulse Wave Imaging, Contrast-Enhanced Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spontaneous Coronary Artery Dissection, Healthy
A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection
The purpose of this research is to compare sympathetic function (flight or fight system) and arterial health including structure and mechanics of participants with history of spontaneous coronary artery dissection (SCAD) to age…
- Trial name
- NCT05699200
- Testing
- Arterial Tonometry, Echocardiogram, Carotid Ultrasounds
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Vertebral Artery Dissection, Cerebrovascular Accident
Changes in Cerebral Blood Flow With Spinal Manipulative Therapy vs. Voluntary Motion
The investigators are performing a study to determine whether changes in blood flow occur in the neck and back of the brain following a series of head positions and a manipulation of the upper neck.
- Conditions
- Vertebral Artery Dissection, Cerebrovascular Accident, Cerebrovascular Stroke
- Trial name
- NCT01205490
- Testing
- head positions and spinal manipulation
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Canadian Memorial Chiropractic College
Spontaneous Coronary Artery Dissection, SCAD
The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry
The primary goal of this project is to describe the clinical and physiologic characteristics of Spontaneous Coronary Artery Dissections (SCAD) in order to increase awareness, understanding, treatment and prevention of a…
- Trial name
- SCAD (NCT01429727)
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic