Clinical trials: Aneurysm Dissecting
Thoracoabdominal Aortic Aneurysm, Thoracoabdominal; Aortic, Aneurysm, Dissecting
Frailty and Physician Modified Fenestrated Endograft for Thoracoabdominal Aortic Pathologies
The primary objective of this single arm, prospective feasibility study, Impact of Frailty on Clinical Outcomes of Patients Treated for Thoracoabdominal and Complex Abdominal Aortic Aneurysms with Physician-Modified Fenestrated…
- Conditions
- Thoracoabdominal Aortic Aneurysm, Thoracoabdominal; Aortic, Aneurysm, Dissecting, Pararenal Aneurysm, Frailty Syndrome
- Trial name
- NCT04524247
- Testing
- Physician Modified Endografts
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Southern California
Coronary Artery Disease
Relationship Between Coronary Angiography Findings and Fractional Flow Reserve After Balloon Angioplasty
The goal of this prospective observational study is to learn about in patients who need percutaneous coronary intervention for coronary artery disease.
- Trial name
- PROBE-FFR (NCT05716997)
- Where
- 2 sites in South Korea
- Volunteers
- 43 people
- Sponsor
- Seoul National University Hospital
SCAD, Addison Disease
Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity
This case control study aims to determine whether spontaneous coronary artery dissection (SCAD) is associated with autoimmune diseases and to update the incidence of SCAD in a population-based cohort.
- Conditions
- SCAD, Addison Disease, Ankylosing Spondylitis, Antiphospholipid Antibody Syndrome
- Trial name
- NCT03941184
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Mayo Clinic
Spontaneous Coronary Artery Dissection
Spanish Registry on Spontaneous Coronary Artery Dissection
Multicenter observational prospective registry, Spanish nationwide-based, of consecutive patients diagnosed with Spontaneous Coronary Artery Dissection (SCAD)
- Trial name
- SR-SCAD (NCT03607981)
- Where
- 37 sites in Spain
- Volunteers
- 300 people
- Sponsor
- Spanish Society of Cardiology
Cerebrovascular Disease, Intracranial Aneurysm
Investigation of Hemodynamics and Radiomics Based on High Resolution Magnetic Resonance Imaging for Predicting the Outcomes of Intracranial Dissecting Aneurysm
This study aims to conduct a comprehensive analysis by integrating clinical factors, aneurysm morphological characteristics, and factors reflecting pathophysiological processes (such as hemodynamic and radiomics features), in…
- Conditions
- Cerebrovascular Disease, Intracranial Aneurysm, Intracranial Arterial Dissection
- Trial name
- NCT07335029
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Beijing Neurosurgical Institute
Coronary Artery Dissection, Spontaneous
Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD
An emerging cause of heart attack in young women is a dissection (or tear) in the coronary arteries. Many of these young women continue to have chest pain long after the tear has healed and this is thought to be due to problems…
- Trial name
- SAFER-SCAD (NCT02008786)
- Testing
- ramipril, rosuvastatin
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Cardiology Research UBC
Spontaneous Coronary Artery Dissection, Spontaneous Coronary Artery Haematoma
The Study of the Prevalence Fibromuscular Dysplasia in Patient With Haematoma or Spontaneous Coronary Artery Dissection.
Spontaneous Coronary Artery Dissection (SCAD) is a rare and often misdiagnosed cause of Acute Coronary Syndrome (ACS) affecting predominantly young women without cardiovascular risk factors.
- Trial name
- DISCO (NCT02799186)
- Testing
- blood sample for genetic analysis
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Clermont-Ferrand
Dissecting Aneurysm of Cerebral Artery, Intramural Hematomas
Atorvastatin in the TREATment of Intracranial Unruptured VertebroBasilar Dissecting Aneurysms
This study was designed to whether there is a measurable reduction in inflammation in walls of unruptured vertebrobasilar dissecting aneurysms with atorvastatin.
- Conditions
- Dissecting Aneurysm of Cerebral Artery, Intramural Hematomas, Inflammation Vascular
- Trial name
- ATREAT-VBD (NCT04943783)
- Testing
- Atorvastatin 20mg
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Beijing Neurosurgical Institute
Spontaneous Coronary Artery Dissection
SCAD : a Registry of Spontaneous Coronary Artery Dissection
Spontaneous coronary artery dissection (SCAD) is an increasingly recognised cause of non-atherosclerotic acute coronary syndromes (ACS), predominantly afflicting young women without conventional atherosclerotic risk factors.
- Trial name
- SCAD (NCT06601270)
- Testing
- There are no interventions as the study is purely observational.
- Where
- 73 sites in Argentina, Austria and 22 more
- Volunteers
- 1,500 people
- Sponsor
- European Society of Cardiology
Aortic Arch; Aneurysm, Dissecting
Guo's Aortic Arch Reconstruction: The First in Man Study of WeFlow-Arch Modular Embedded Branch Stent Graft System
This study is the first in man study of WeFlow-Arch Module Embedded Aorta Arch Stent Graft System
- Trial name
- NCT04764370
- Testing
- WeFlow-Ach Moduler Embedded Branch Stent Graft System
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Aortic Dissection, Intramural Hematoma
DARTS I Feasibility Study
The objective of this study is to investigate the feasibility and clinical benefits of the AMDS to treat patients with acute DeBakey type I dissections and/or intramural hematomas (IMH) involving the ascending aorta and aortic…
- Trial name
- DARTS I (NCT03035643)
- Testing
- AMDS
- Where
- 5 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Ascyrus Medical LLC.
Thoracic Aortic Aneurysms, Dissecting, Aneurysm
Endovascular Treatment of Thoracic Aortic Disease
The purpose of this study is to assess the role endovascular therapy to treat aortic disease involving the ascending aorta, the aortic arch, and the visceral segment of the aorta (or thoracoabdominal aorta)
- Conditions
- Thoracic Aortic Aneurysms, Dissecting, Aneurysm, Ascending Aorta Aneurysm, Aortic Arch; Aneurysm, Dissecting
- Trial name
- EVOLVE Aorta (NCT00583817)
- Testing
- Endovascular stent-graft implantation
- Where
- 2 sites in United States
- Volunteers
- 170 people
- Sponsor
- Matthew Eagleton
Vertebral Artery Dissection, Cerebrovascular Accident
Changes in Cerebral Blood Flow With Spinal Manipulative Therapy vs. Voluntary Motion
The investigators are performing a study to determine whether changes in blood flow occur in the neck and back of the brain following a series of head positions and a manipulation of the upper neck.
- Conditions
- Vertebral Artery Dissection, Cerebrovascular Accident, Cerebrovascular Stroke
- Trial name
- NCT01205490
- Testing
- head positions and spinal manipulation
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Canadian Memorial Chiropractic College
Aortic Aneurysm, Aortic Dissection
Clinical Investigation of Clinical Safety and Performance of the SP-GRIPFLOW, Selective Cerebral Perfusion Catheter When Used for Cerebral Perfusion During Aortic Arch Repair
The purpose of this study is to determine if the SP-GRIPFLOW catheter (the catheter designed by Fuji Systems) is safe and how well it functions.
- Conditions
- Aortic Aneurysm, Aortic Dissection, Aortic Arch Aneurysm, Aortic Arch; Aneurysm, Dissecting
- Trial name
- NCT05421130
- Testing
- Selective Cerebral Perfusion Catheter
- Where
- 5 sites in Germany, Netherlands
- Volunteers
- 149 people
- Sponsor
- Fuji Systems Corporation
Spontaneous Coronary Artery Dissection, SCAD
Canadian SCAD Study
Natural history multicenter, prospective, observational registry with 10-year follow-up
- Conditions
- Spontaneous Coronary Artery Dissection, SCAD, Fibromuscular Dysplasia
- Trial name
- NCT04906356
- Testing
- Genetic sub-study
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- Cardiology Research UBC
Cervical Artery Dissection
Antithrombotic Treatment Strategies in Cervical Artery Dissection
The goal of this clinical randomised controlled trial is to compare two treatment strategies - antiplatelet treatment strategy versus anticoagulation treatment strategy - in patients with acute, ischemic Cervical Artery…
- Trial name
- TREAT-CAD 2 (NCT07639892)
- Testing
- Antiplatelet Treatment Strategy, Anticoagulation Treatment Strategy
- Volunteers
- 1,100 people
- Sponsor
- University Department of Geriatric Medicine FELIX PLATTER
PAD - Peripheral Arterial Disease, PAD
Tack Optimized Balloon Angioplasty Post-Market Study
The objective of this study is to obtain outcomes following dissection repair with the Tack Endovascular System in a broad population of patients undergoing endovascular treatment of lesions within the superficial femoral…
- Conditions
- PAD - Peripheral Arterial Disease, PAD, Dissection, Arterial Dissection
- Trial name
- TOBA PMS (NCT05361967)
- Testing
- The Tack Endovascular System
- Where
- 10 sites in United States
- Volunteers
- 6 people
- Sponsor
- Spectranetics Corporation
Aortic Dissection
Study Comparing Hemiarch Replacement and Hemiarch Plus Stent Implantation in Acute Aortic Dissection
Acute DeBakey type I aortic dissection (ATAD) is one of the most lethal surgical emergencies. The conventional operative strategy is hemiarch replacement under cardiopulmonary bypass support to replace the diseased segment of the…
- Trial name
- RADAR (NCT06044259)
- Testing
- AMDS; Artivion, Atlanta, Georgia, US, Conventional hemiarch replacement
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Chinese University of Hong Kong
Horner's Syndrome, Stroke
Pupillometry in Horner's Syndrome
Horner's syndrome (HS) is a result of interruption of the sympathetic innervation to the eye and ocular adnexa, which can occur due to carotid artery dissection (CAD), along which the sympathetic nerve fibers travel to reach the…
- Conditions
- Horner's Syndrome, Stroke, Dissection Carotid Artery
- Trial name
- NCT02978079
- Testing
- Automated pupillometry
- Where
- Switzerland
- Volunteers
- 135 people
- Sponsor
- University of Zurich
Coronary Artery Dissection, Spontaneous
Spontaneous Coronary Artery Dissection anaLysIs of the Brazilian Updated Registry
A retrospective and prospective registry will evaluate demographic and angiographic data in patients with spontaneous coronary artery dissection (SCAD) using medical records, invasive coronary angiography, intravascular imaging…
- Trial name
- SCALIBUR (NCT03398850)
- Where
- Brazil
- Volunteers
- 250 people
- Sponsor
- Hospital Israelita Albert Einstein