Clinical trials: Angina Pectoris With Normal Coronary Arteriogram
Ischemic Heart Disease, Coronary Microvascular Disease
MCG as a Noninvasive Diagnostic Strategy for Suspected INOCA (MICRO2)
A prospective, multicenter, observational, single-arm trial to validate CardioFlux MCG's ability to diagnose myocardial ischemia caused by coronary microvascular dysfunction in patients with suspected ischemia and confirmed no…
- Conditions
- Ischemic Heart Disease, Coronary Microvascular Disease, Angina, Myocardial Ischemia
- Trial name
- MICRO2 (NCT06212466)
- Testing
- CardioFlux
- Where
- 8 sites in United States
- Volunteers
- 136 people
- Sponsor
- Genetesis Inc.
Microvascular Angina, Microvascular Coronary Artery Disease
EUROpean Coronary microCirculatory Resistance and Absolute Flow Trial
Rationale: coronary microvascular disease is a relatively 'new' entity within the field of cardiology. The investigators are able to investigate the microcirculation by measurements performed in the catheterization laboratory.
- Conditions
- Microvascular Angina, Microvascular Coronary Artery Disease, Coronary Vasospasm, Microvascular Resistance
- Trial name
- EURO-ccraft (NCT04598308)
- Testing
- absolute flow and resistance measurements
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Coronary Microvascular Disease, Ischemic Heart Disease
A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction
Among patients with stable ischemic heart disease who are referred for coronary angiography, a substantial proportion have non-obstructive coronary artery disease (CAD).
- Conditions
- Coronary Microvascular Disease, Ischemic Heart Disease, Myocardial Ischemia
- Trial name
- NCT03537586
- Testing
- Bivalirudin, Adenosine, Heparin
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- NYU Langone Health
Microvascular Angina
Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot Study
40% of patients presenting with stable chest pain (angina) have no significant blockage of the main heart arteries. Identifying why these patients have symptoms will mean better treatment options can be developed.
- Trial name
- NCT06070662
- Testing
- Coronary microvascular disease testing during coronary angiography, Cardiac magnetic resonance scan including exercise, Additional analysis of already acquired CT scan
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Leicester
Metabolic Syndrome X
The Improvements of Dietary Supplement of Black Rice on Metabolic Syndrome
The purpose of this study is to thoroughly investigate how the interaction between black rice and human gut microbiota affects metabolic diseases, this study will recruit patients with Metabolic Syndrome (MS) and provide them…
- Trial name
- IDSBRMS (NCT02407522)
- Testing
- Black rice, follow-up
- Volunteers
- 101 people
- Sponsor
- Sun Yat-sen University
Coronary Microvascular Dysfunction, Coronary Microvascular Disease
Insulin Resistance and Coronary Microvascular Dysfunction in Patients With Myocardial Ischemia and Non-obstructive Coronary Artery Disease
The goal of this prospective study is to assess the correlation between coronary microvascular disfunction and insulin resistance in patients with INOCA.
- Conditions
- Coronary Microvascular Dysfunction, Coronary Microvascular Disease, Insulin Resistance
- Trial name
- IRIN (NCT06597851)
- Testing
- Thermodilution based assessment of coronary microcirculation, Hyperinsulinemic-euglycemic Clamp test
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Stomach Neoplasms, Metabolic Syndrome X
Effects of Prehabilitation in Gastric Cancer Patients With Metabolic Syndrome on Perioperative Outcome
A prospective randomised controlled trial to investigate the effects of a pre-operative prehabilitation protocol on clinical outcomes of gastric cancer patients with metabolic syndrome who undergo laparoscopic radical…
- Trial name
- NCT02649348
- Testing
- pre-operative prehabilitation
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Qingdao University
Cardiovascular Diseases, Heart Diseases
Peripheral Effects of Exercise on Cardiovascular Health (STRRIDE I)
To investigate the separate effects of the amount of exercise and exercise intensity on cardiovascular risk factors in overweight men and women with mild to moderate dyslipidemia.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Hyperlipidemia
- Trial name
- NCT00200993
- Testing
- physical activity
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Leukemia, Metabolic Syndrome X
Adipokines as Predictors of the Metabolic Syndrome in ALL Survivors
Background: Acute Lymphoblastic Leukemia (ALL) is the most common malignancy in children. It accounts for 25% of all childhood cancers. Peak incidence occurs between 2 to 5 years of age.
- Trial name
- NCT00566566
- Testing
- sample without DNA
- Volunteers
- 150 people
- Sponsor
- Sheba Medical Center
Metabolic Syndrome X
Effect of Dapagliflozin Administration on Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion
The Metabolic Syndrome is a high prevalence disease worldwide. About a quarter of the adult population suffers the disease. Dapagliflozin is an inhibitor of the sodium-glucose co-transporter SGLT2 in the kidney and is a novel…
- Trial name
- NCT02113241
- Testing
- Dapagliflozin
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- University of Guadalajara
Metabolic Syndrome X
ProAlgaZyme Novel Algae Infusion: Applications in Metabolic Syndrome
The purpose of this study is to compare the effects of supplementation with ProAlgaZyme (a novel fermentation product of a freshwater algae ecosystem) vs.
- Trial name
- NCT00489333
- Testing
- ProAlgaZyme
- Where
- Cameroon
- Volunteers
- 52 people
- Sponsor
- Health Enhancement Products, Inc.
Coronary Microvascular Disease, CMD
Impact of Exercise Training on Ischemia With Non-Obstructive Coronary Arteries (INOCA): The ExINOCA Study
The purpose of the study is to identify causes of chest pain in patients experiencing chest pain with no signs of narrowing of the coronary arteries of the heart, and to investigate whether physical exercise can improve coronary…
- Trial name
- ExINOCA (NCT06529848)
- Testing
- Exercise training
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Bispebjerg Hospital
Coronary Microvascular Disease
An Observational Study of Coronary Microvascular Disease of China
Non-obstructive coronary heart disease refers to patients with angina pectoris without significant narrowing of the epicardial vessels.
- Trial name
- CCMD (NCT06676137)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Metabolic Syndrome X, Lifestyle-related Condition
Metabolic Risk Management, Physical Exercise and Lifestyle Counselling in Low-active Adults; Controlled Randomized Trial
The purpose of this study is evaluate the effectiveness of different doses of supervised exercise training intensity -concomitant to lifestyle counselling- as a Primary Health Care intervention tool for the management of the…
- Conditions
- Metabolic Syndrome X, Lifestyle-related Condition, Lifestyle Risk Reduction, Cardiovascular Risk Factor
- Trial name
- BELLUGAT (NCT02832453)
- Testing
- Lifestyle, Aerobic interval training, Traditional continous training
- Where
- Spain
- Volunteers
- 77 people
- Sponsor
- INEFC-Lleida
Morbid Obesity, Metabolic Syndrome X
Randomized Comparison of Laparoscopic Sleeve Gastrectomy and Gastric Bypass for Morbid Obesity
Bariatric surgery is the most effective treatment for morbid obesity. Roux-en-Y gastric bypass (RYGB) is a bariatric procedure with known safety and effectiveness.
- Conditions
- Morbid Obesity, Metabolic Syndrome X, Diabetes Mellitus, Dyslipidemia
- Trial name
- NCT01806506
- Testing
- Laparoscopic sleeve gastrectomy, Roux-en-Y Gastric Bypass
- Where
- Poland
- Volunteers
- 72 people
- Sponsor
- Medical University of Warsaw
Metabolic Syndrome X, Heart Disease
Dairy Products and Metabolic Effects (Norwegian Part)
Foods containing more dairy fat (and thus a higher proportion of short and medium chain fatty acids and possibly some other nutrients or micronutrients with effect on energy intake, satiety or energy metabolism) affect energy…
- Trial name
- NCT00140816
- Testing
- Increased intake of dairy products
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Metabolic Syndrome X, Nutritional and Metabolic Diseases
Nutrition and Lifestyle Behaviour Peer Support Program Among Malaysian Adults With Metabolic Syndrome (PERSUADE)
The outlook of a community-based intervention targeting nutrition and lifestyle behaviour modification among adults with metabolic syndrome (MetS) has not been fully explored.
- Conditions
- Metabolic Syndrome X, Nutritional and Metabolic Diseases, Health Behavior
- Trial name
- PERSUADE (NCT03417128)
- Testing
- Peer support
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Monash University
Overweight, Metabolic Syndrome X
Effects of NUTRIOSE®FB Dietary Fiber Supplementation on Satiety, Body Fat, and Metabolic Syndrome in Overweight Adult Men
The purpose of this study was to determine the effects of NUTRIOSE® supplementation on body composition, satiety, and determinants of metabolic syndrome in overweight men.
- Trial name
- NCT01044680
- Testing
- NUTRIOSE
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Roquette Freres
Prediabetic State, Obesity
Pancreatic Islet Function, Insulin Sensitivity, and Chronic Complications in Pre-Diabetes
We, the investigators at National Taiwan University Hospital, want to compare patients' islet cell function, insulin sensitivity and risk of chronic complications with normal subjects.
- Conditions
- Prediabetic State, Obesity, Metabolic Syndrome X
- Trial name
- NCT00172796
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Metabolic Syndrome X
ROMEO (Rosuvastatin in Metabolic syndrOme)
The primary objective of this study is to compare the effect of rosuvastatin 10mg with atorvastatin 10mg after 6 weeks of treatment in the ratio of ApoB/ApoA1 in subjects with metabolic syndrome.
- Trial name
- NCT00395486
- Testing
- Rosuvastatin, Atorvastatin
- Where
- 3 sites in South Korea
- Volunteers
- 258 people
- Sponsor
- AstraZeneca