Clinical trials: Anginal Pain
Coronary Artery Disease, Angina (stable)
Performance of the Acoustic Based CADScor System in Coronary Artery Disease
The purpose of this study is to determine if the CAD Score, collected from the CADscore system, performs as well as the Coronary CTA in determining Coronary Artery Disease, in low to intermediate risk patients that are referred…
- Trial name
- NCT06655779
- Testing
- Acoustic Detection of Blood Flow
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- INTEGRIS Baptist Medical Center
Acute Myocardial Infarction, Cardiovascular Morbidity
Dapagliflozin Effects on Mayor Adverse Cardiovascular Events in Patients With Acute Myocardial Infarction (DAPA-AMI)
The actual evidence is solid about the use of de SGLT2-inhibitors in wide spectrum of cardiorenal targets, which has been shown in a great amount of randomized clinical trials compared with placebo.
- Conditions
- Acute Myocardial Infarction, Cardiovascular Morbidity, Heart Failure, Angina, Unstable
- Trial name
- DAPA-AMI (NCT04717986)
- Testing
- Dapagliflozin 10Mg Tab
- Where
- Mexico
- Volunteers
- 188 people
- Sponsor
- Instituto Mexicano del Seguro Social
Coronary Artery Disease, Angina Pectoris
The OCT SORT-OUT VIII Study
The purpose of this study is to compare early vessel healing after implantation of SYNERGY drug eluting stent (DES) or BioMatrix NeoFlex DES at one and three months in two cohorts.
- Conditions
- Coronary Artery Disease, Angina Pectoris, Myocardial Infarction
- Trial name
- OCT SORT-OUT (NCT02253108)
- Testing
- Everolimus eluting bioresorbable polymer stent, Biolimus eluting bioresorbable polymer stent
- Where
- 2 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- Aarhus University Hospital Skejby
Unstable Angina
Research on the Clinical Effect of Effective Prescription in Treating Unstable Angina.
This study evaluates the clinical efficacy of the famous prescription in the treatment of unstable angina pectoris. All of the patients will be divided into 4 arms according to their syndrome type.
- Trial name
- NCT03171597
- Testing
- Anti-Platelet Drugs, Lipid Regulating Drugs, Coronary Vasodilator
- Volunteers
- 240 people
- Sponsor
- Jun Li
Stroke, Stroke, Ischemic
Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis
REDUCING INFLAMMATION IN ISCHEMIC STROKE WITH COLCHICINE, AND TICAGRELOR IN HIGH-RISK PATIENTS-EXTENDED TREATMENT IN ISCHEMIC STROKE.
- Conditions
- Stroke, Stroke, Ischemic, Atherosclerosis, Myocardial Infarction
- Trial name
- RIISC-THETIS (NCT05476991)
- Testing
- Colchicine 0.5 MG, Ticagrelor 90mg, Aspirin 75-300mg
- Where
- France
- Volunteers
- 2,800 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease, Stable Angina
Physiology as Guidance to Evaluate the Direct Impact of Coronary Lesion Treatment: The PREDICT Study
The purpose of this study is to assess whether the use of physiology parameters as guidance post-percutaneous coronary interventions (PCI) is associated with less risks of target vessel failure (TVF) and angina-related events…
- Conditions
- Coronary Artery Disease, Stable Angina, Unstable Angina, Ischemic Heart Disease
- Trial name
- EASY-PREDICT (NCT04929496)
- Testing
- post-PCI FFR
- Where
- Canada
- Volunteers
- 221 people
- Sponsor
- Laval University
Coronary Heart Disease, Angina Pectoris
Aspirin Non-responsiveness and Clopidogrel Endpoint Trial.
In the ASCET study, 1000 patients with documented coronary heart disease will be randomized to either continued treatment with aspirin 160 mg/d or change to clopidogrel 75mg/d.
- Conditions
- Coronary Heart Disease, Angina Pectoris, Atherosclerosis
- Trial name
- ASCET (NCT00222261)
- Testing
- aspirin, clopidogrel
- Where
- Norway
- Volunteers
- 1,001 people
- Sponsor
- Ullevaal University Hospital
Acute Coronary Syndrome, Myocardial Infarction
Rule Out Myocardial Infarction by Computer Assisted Tomography
The goal of this research is to determine noninvasively whether detection of coronary stenosis and plaque by multidetector computed tomography (MDCT) in patients with acute chest pain suspected of acute coronary syndrome (ACS)…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Unstable Angina Pectoris
- Trial name
- ROMICAT (NCT00990262)
- Testing
- Cardiac Computed Tomography
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- Massachusetts General Hospital
Coronary Microvascular Disease
An Observational Study of Coronary Microvascular Disease of China
Non-obstructive coronary heart disease refers to patients with angina pectoris without significant narrowing of the epicardial vessels.
- Trial name
- CCMD (NCT06676137)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Stroke, Not Specified as Hemorrhage or Infarction, Angina Pectoris
Clinical Study of Medicinal Product Cardionat® Using in Health Athlete Volunteers
The objective of this study is to evaluate the long-term plasma and urine pharmacokinetic parameters of Cardionat®, capsules 250 mg, when used in healthy athlete volunteers. The study consists of four steps: Step 1.
- Trial name
- NCT02758912
- Testing
- оral intake of study drug capsules; study drug - Cardionat ® (trimethylhydrazinium propionate dihydrate), oral capsules 250 mg
- Where
- Russia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Burnasyan Federal Medical Biophysical Center
Stable Angina
Comparison of Vascular Remodeling Between Different Antianginal Medication Evaluated by Noninvasive ECG-gated Fundus Photographic Evaluation
Treatments for stable angina includes drug therapy such as calcium-channel blocker, beta blocker, and ACEI/ARB. To obtain good prognosis in patients with coronary artery disease,preventing or correcting the progression of…
- Trial name
- NCT01162902
- Testing
- Diltiazem treated group, Bisoprolol treated group, Candesartan treated group
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Angina Pectoris
Myocardial Ischemia After Coronary Sinus Reduction Stent Implantation
Chronic angina pectoris refractory to medical and revascularization therapies is a disabling medical condition and a major public health problem. Patients with refractory angina have limited treatment options.
- Trial name
- MICS-Reduce (NCT06033495)
- Testing
- Coronary sinus reduction stent
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Stable Angina, Coronary Artery Disease
Impact of Rotational Atherectomy on Coronary Microcirculation
The purpose of this observational study is to compare the impact of rotational atherectomy to conventional stenting and to investigate how it may affect coronary microcirculation in patients with calcified coronary artery lesions…
- Trial name
- MICRO-ROTA (NCT05771961)
- Testing
- coronary pressure/temperature sensor-tipped guidewire, Angiography-derived index of microcirculatory resistance (IMRangio)
- Where
- Lithuania
- Volunteers
- 300 people
- Sponsor
- Lithuanian University of Health Sciences
Coronary Artery Disease
The "CAD-Man" EXTEND Study
CAD-Man Extend is the long-term follow-up (clinical, laboratory, and computed tomography (CT) imaging) of a single-center, randomized, controlled CAD-Man trial comparing a CT-first strategy with a direct- invasive coronary…
- Trial name
- CAD-Man-EXTEND (NCT06237673)
- Testing
- CT, invasive coronary angiography (ICA)
- Where
- Germany
- Volunteers
- 318 people
- Sponsor
- Charite University, Berlin, Germany
Myocardial Infarction, Unstable Angina
CORonary Diet Intervention With Olive Oil and Cardiovascular PREVention
The purpose of this study is to compare the effects of the consumption of two different dietary patterns (low fat versus Mediterranean Diet) on the incidence of cardiovascular events of persons with coronary disease.
- Conditions
- Myocardial Infarction, Unstable Angina, Malignancy, Cognitive Decline
- Trial name
- CORDIOPREV (NCT00924937)
- Testing
- Mediterranean Diet, Low Fat Diet
- Where
- Spain
- Volunteers
- 1,002 people
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Thromboembolism
Michelangelo - Oasis 5
Study Objectives PRIMARY OBJECTIVE: To evaluate whether fondaparinux is at least as effective as or superior to enoxaparin in preventing death, myocardial infarction or refactory ischemia up to Day 9 in the acute treatment of…
- Trial name
- NCT00139815
- Testing
- Fondaparinux, enoxaparin
- Volunteers
- 20,078 people
- Sponsor
- GlaxoSmithKline
Coronary Artery Disease, Angina
Ivabradine and Post-revascularisation Microcirculatory Dysfunction
The aim of the study is to test whether, in patients with angina and flow limiting epicardial coronary artery disease, pre-treatment with Ivabradine, as opposed to beta blockers, will reduce post percutaneous coronary…
- Trial name
- MICRO-PCI (NCT02507050)
- Testing
- Ivabradine
- Where
- United Kingdom
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Coronary Artery Disease, Angina (Stable)
Coronary Sinus Reducer Therapy for Persisting Angina
Refractory angina due to advanced obstructive coronary artery disease (CAD) remains a major clinical problem with limited evidence-based treatment options.
- Trial name
- REDUCE ANGINA (NCT07485985)
- Testing
- Coronary sinus reducer
- Volunteers
- 25 people
- Sponsor
- UMC Utrecht
Multivessel Coronary Artery Disease, Vessel Disease
Functional Testing Underlying Coronary Revascularisation
The objective of this trial is to compare the clinical outcomes and cost-effectiveness of 2 therapeutic strategies, one based on coronary angiography guidance and the other based on coronary angiography with fractional flow…
- Conditions
- Multivessel Coronary Artery Disease, Vessel Disease, Stable Angina, Unstable Angina or Stabilized Non-ST Elevated Myocardial Infarction
- Trial name
- FUTURE (NCT01881555)
- Testing
- invasive coronary angiography, Functional testing by fractional flow reserve measurement
- Where
- France
- Volunteers
- 941 people
- Sponsor
- Hospices Civils de Lyon
Triple Vessel Disease, Unstable Angina
Comparison of Saphenous Vein Graft Harvested From Upper Versus Lower Leg in Coronary Artery Bypass Grafting
In coronary artery bypass grafting, saphenous veins are widely used as a composite grafts that are Y-anastomosed to in-situ left internal thoracic artery.
- Conditions
- Triple Vessel Disease, Unstable Angina, Stable Angina, Myocardial Infarction
- Trial name
- COSAVEGUL-1 (NCT01974492)
- Testing
- Upper leg vein harvesting, Lower leg vein harvesting
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Seoul National University Hospital
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