Clinical trials: Anginal Pain
Coronary Artery Disease
BIOFLOW III Satellite-ELADIS Orsiro Stent System
This registry is a clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT02029092
- Where
- 14 sites in Spain
- Volunteers
- 404 people
- Sponsor
- C.E.M. Biotronik, S.A.
Coronary Artery Disease, Myocardial Infarction
Compressive Elastic Dressing Versus TR Band
Radial approach is widely established in cardiac diagnostic and therapeutic treatments. It has been shown to decrease bleeding, vascular problems, and mortality rates when compared to the femoral approach.
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Angina, Unstable, Angina, Stable
- Trial name
- Band Vs Gauze (NCT05409716)
- Testing
- Compressive Elastic dressing for hemostasis in cardiac procedure using radial approach, Wristband TR band for hemostasis in cardiac procedure using radial approach
- Where
- 2 sites in Palestinian Territories
- Volunteers
- 400 people
- Sponsor
- An-Najah National University
Stable Angina Pectoris, Acute Coronary Syndrome
Randomized "All-comer" Evaluation of a Permanent Polymer Resolute Integrity Stent Versus a Polymer Free Cre8 Stent
The study objective is to assess the safety and efficacy of the Permanent Polymer Zotarolimus-Eluting Stent Resolute Integrity™ to the Polymer Free Amphilimus-Eluting Stent Cre8™ compared in an all-comer patient population.
- Trial name
- NCT02328898
- Testing
- Cre8 Stent, Resolute Integrity stent
- Where
- 3 sites in Luxembourg, Netherlands
- Volunteers
- 1,532 people
- Sponsor
- UMC Utrecht
Ekg Change Ischemia Lateral
Diagnostic Value of Electrocardiographic St-t Wave Changes in Patients With Chronic Stable Angina
The electrocardiogram (ECG) is a simple and non-invasive bedside diagnostic tool with a well-established role in the diagnosis of (CAD).
- Trial name
- ECG (NCT02027506)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Alexandria University
Angina Pectoris, Variant, Statins, HMG-CoA
Statin Therapy In Patients With Vasospastic Angina
The purpose of this study is to evaluate whether statin is effective in the treatment of vasospastic angina.
- Trial name
- STAVA (NCT02790528)
- Testing
- Atorvastatin
- Where
- South Korea
- Sponsor
- Seung-Jung Park
Stable Angina, Non ST Segment Elevation Myocardial Infarction
INsTantenous wavE-Free Ratio-guided PCI Versus Fractional Flow REserve-Guided PCI in rouTine Clinical Practice, Prospective, Multicenter Registry
The current study sought to evaluate the clinical relevance of iFR-guided strategy in real world clinical practice using unrestricted study population from stable angina to acute coronary syndrome including acute ST-segment…
- Conditions
- Stable Angina, Non ST Segment Elevation Myocardial Infarction, ST-segment Elevation Myocardial Infarction, Silent Myocardial Ischemia
- Trial name
- INTERPRET (NCT03338309)
- Testing
- Instantaneous wave-free ratio measurement
- Where
- 4 sites in South Korea
- Volunteers
- 1,200 people
- Sponsor
- Samsung Medical Center
Coronary Heart Disease, Unstable Angina
Efficacy and Safety of Wen Xin Granules for the Treatment of Unstable Angina Pectoris
This is a double-blind, randomized placebo-controlled trial which aims to evaluate the efficacy and safety of Wen Xin granule in patients with unstable angina pectoris.
- Conditions
- Coronary Heart Disease, Unstable Angina, Chinese Herbal Medicine
- Trial name
- NCT04661709
- Testing
- Wen Xin granule, Clopidogrel Hydrogen Sulfate 75 MG Oral Tablet, Atorvastatin Calcium
- Volunteers
- 502 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Coronary Microvascular Disease
Clinical Evaluation of Aromatic Wentong in the Treatment of Coronary Microvascular Disease
Coronary Microvascular Disease (CMD) is a condition where patients experience chest pain (angina) even though their coronary arteries appear normal on angiography.
- Trial name
- NCT06901570
- Testing
- Kuangxiong Aerosol
- Where
- China
- Volunteers
- 528 people
- Sponsor
- China-Japan Friendship Hospital
Coronary Microvascular Disease, Cardiac Pacemaker Syndrome
The Effects of Trans Venous Cardiac Pacing on Coronary Microvascular Function and Hemodynamics
The study will examine role of transvenous pacing on coronary microcirculation.
- Trial name
- NCT03917251
- Testing
- Coronary flow and pressure measurement in patients with ventricular pacing
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Angina
Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina
The purpose of this study is to evaluate the effect of febuxostat, once daily (QD), compared to placebo as an add on to stable anti-anginal therapy, on the total exercise time of participants with Chronic Stable Angina.
- Trial name
- NCT01549977
- Testing
- Febuxostat
- Where
- 21 sites in United States
- Volunteers
- 1 people
- Sponsor
- Takeda
Acute Coronary Syndrome, Percutaneous Coronary Intervention
A Cohort of Patients Undergoing Percutaneous Coronary Intervention
To investigate the risk factors involved in the occurrence and prognosis of the patients with acute coronary syndrome, patients undergoing percutaneous coronary intervention will be recruited and followed up for at least 2 years.
- Conditions
- Acute Coronary Syndrome, Percutaneous Coronary Intervention, Myocardial Infarction, Unstable Angina
- Trial name
- APCIcohort (NCT05719545)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Su Guohai
Acute Coronary Syndrome
A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome
Ticagrelor is a new, reversible binding, anti-platelet medication. Anti-platelet medications work to prevent the formation of blood clots.
- Trial name
- PLATO (NCT00391872)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 672 sites in United States, Argentina and 42 more
- Volunteers
- 18,624 people
- Sponsor
- AstraZeneca
Angina Pectoris
Women With Chest Pain and no Significant Coronary Artery Stenosis; A Study on Microvascular Resistance
Female patients presenting with persistent chest pain despite no obstructive coronary artery disease have impaired prognosis. Stress tests are often positive or inconclusive.
- Trial name
- NCT01582165
- Testing
- Rosuvastatin
- Where
- Norway
- Volunteers
- 66 people
- Sponsor
- Oslo University Hospital
Coronary Artery Disease, Atherosclerosis, Coronary
Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
The objective of this study is to assess the safety and efficacy of the Orsiro Sirolimus Eluting Coronary Stent System in the treatment of subjects with up to three native de novo or restenotic (standard PTCA only) coronary…
- Conditions
- Coronary Artery Disease, Atherosclerosis, Coronary, Myocardial Ischemia, Ischemic Heart Disease
- Trial name
- BIOFLOW-V (NCT02389946)
- Testing
- Orsiro DES, Xience DES
- Where
- 92 sites in United States, Australia and 11 more
- Volunteers
- 1,334 people
- Sponsor
- Biotronik, Inc.
Angina (Stable), Ischemic Heart Disease (IHD)
Angina After PCI: a Systems Medicine Study
Angina may persist or recur in patients treated by coronary angioplasty. The angioplasty involves a balloon treatment to open a blocked heart blood vessel and usually a stent (thin metal tube) is placed.
- Trial name
- CorMicA-PCI (NCT06854302)
- Testing
- Cardiovascular magnetic resonance imaging, Coronary physiology
- Where
- 4 sites in United Kingdom
- Volunteers
- 600 people
- Sponsor
- NHS National Waiting Times Centre Board
Coronary Stenosis, Angina Pectoris
Evaluation of the Correlation Between the Coronary Stenosis Degree With FFRCT and the Grade of Stable Angina Pectoris
Angina pectoris is the most common clinical manifestation of coronary heart disease（CHD）, which is the main feature of chest pain caused by transient myocardial ischemia.
- Trial name
- NCT02802046
- Testing
- Computed tomographic angiography of coronary artery
- Volunteers
- 20 people
- Sponsor
- Guiyang No.4 People's Hospital
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Myocardial Infarction
Telerehabilitation in Coronary Heart Disease
Cardiovascular diseases are the main cause of death worldwide. Aerobic fitness is related to long-term survival and a reduction in mortality and recurrent nonfatal myocardial infarction in subjects with cardiovascular disease.
- Conditions
- Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Myocardial Infarction, Percutaneous Transluminal Cutting Balloon Angioplasty of Popliteal Vein Using Fluoroscopic Guidance
- Trial name
- TRiCH (NCT02047942)
- Testing
- Center-based cardiac rehabilitation, Home-based training with telemonitoring guidance
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Coronary Artery Disease, Stable Angina
Optimal Predilatation Treatment Before Implantation of a Magmaris Bioresorbable Scaffold in Coronary Artery Stenosis
The aim of the study is to investigate if lesion preparation with a ScoreFlex balloon compared to a standard non-compliant balloon improve vascular healing and minimize lumen reduction after implantation of a Magmaris…
- Conditions
- Coronary Artery Disease, Stable Angina, Coronary Artery Stenosis, Myocardial Infarction
- Trial name
- OPTIMIS (NCT04666584)
- Testing
- ScoreFlex balloon, Device: standard non-compliant balloon
- Where
- Denmark
- Volunteers
- 82 people
- Sponsor
- Odense University Hospital
Microvascular Angina
PRIZE ET Sub-Study
Microvascular angina (MVA) is caused by abnormalities of the small blood vessels in the heart. Endothelin-1 (ET-1) is a chemical messenger that circulates and accumulates in the blood vessel walls, causing them to narrow or go…
- Trial name
- NCT04508998
- Testing
- Blood tests including genotyping, Exercise Tolerance Test
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Coronary Artery Disease, Angina Pectoris
PREcise Percutaneous Coronary Intervention for Stent OptimizatION in Treatment of COMPLEX Lesion (PRECISION-COMPLEX)
The aim of the study is to compare post-interventional fractional flow reserve (FFR) value between optical coherence tomography(OCT)-guided and angiography-guided strategy for treatment of complex coronary lesion.
- Trial name
- NCT05493904
- Testing
- OCT-guided PCI, Angiography-guided PCI, Drug-eluting stent
- Where
- 4 sites in South Korea
- Volunteers
- 320 people
- Sponsor
- Chonnam National University Hospital
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