Clinical trials: Animal Model
Lymphedema of Upper Limb
Novel MRI Techniques on Evaluation of Lymphedema
In this project, the investigators aim to investigate the imaging approaches for breast cancer-related secondary lymphedema. The clinical study aims to optimize the conventional MRI methods for mapping lymphedema and assess the…
- Trial name
- NCT05804643
- Testing
- Diffusion magnetic resonance imaging
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Dietary Habits
Adhering to Dietary Approaches for Personal Taste (ADAPT)
Understanding the impact of dietary patterns, exercise, and behavior change in the prevention of disease is paramount to improving the health and well-being of future generations and economies.
- Trial name
- NCT03226938
- Where
- United States
- Volunteers
- 3,001 people, healthy volunteers welcome
- Sponsor
- Tufts University
Eating Behavior
An Application of Models Predicting the Eating Rate of Bread Using Sensory and Instrumental Texture
Rationale: The world-wide rising obesity rates are a major health problem. Therefore, people should moderate food intake. A lower eating rate will decrease the energy intake.
- Trial name
- BOP (NCT05185765)
- Testing
- Bread
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Language and Speech Disorder, Psychiatric Nursing, Mental Health, Pet Therap
The Effect of Animal-Assisted Activity Programme Based on Human Caring Theory on Perceived Stress, Social Adaptation and Communication Skills of Children With Speech and Language Disorders
Animal-assisted practice is an intervention method explained with different mechanisms and theories that provides protection and development of health through human-animal interaction.
- Trial name
- NCT07512180
- Testing
- Nursing Care
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Şeyma Demiralay
The Apparatus for Processing the Tubular Graft Modification Will be Designed and Evaluated., The On-site Capturing of the Endothelial (Progenitor) Cells by Peptide-mediated Selective Adhesion in Vitro and in Vivo Will Also be Elucidated.
Endothelialized ePTFE Graft by Nanobiotechnology
The replacement of autologous blood vessels by artificial grafts is urgently needed in clinical applications. Expanded polytetrafluoroethylene (ePTFE) grafts are the most clinically used artificial blood vessels because of its…
- Conditions
- The Apparatus for Processing the Tubular Graft Modification Will be Designed and Evaluated., The On-site Capturing of the Endothelial (Progenitor) Cells by Peptide-mediated Selective Adhesion in Vitro and in Vivo Will Also be Elucidated., The Patency Rate of ITRI-made Artificial Blood Vessels Will be Evaluated by the Porcine Animal Model.
- Trial name
- NCT02002104
- Where
- Taiwan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
HIV Infections
The Effectiveness of Human Antibodies in Influencing an AIDS-Like Disease in Monkeys
The purpose of this study is to see if an investigational vaccine can make antibodies (proteins found in blood) in humans that will influence the course of an AIDS-like disease in monkeys.
- Trial name
- NCT00031109
- Testing
- gp160 MN/LAI-2, Aluminum hydroxide
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
CMT, CMT (Charcot Marie Tooth Disease)
A Multi-omic Approach to the Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A Disease (CMT1A)
The most common inherited neuropathy is Charcot-Marie-Tooth disease type 1A (CMT1A), caused by a duplication of the gene expressing PMP22.
- Conditions
- CMT, CMT (Charcot Marie Tooth Disease), CMT - Charcot-Marie-Tooth Disease, CMT1A
- Trial name
- CMT-MODs (NCT07476365)
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Sjogren's Syndrome
Functional Analysis of Salivary Glands and Correlation With Sialoscintigraphy in Sjogren's Syndrome
Sjögren's syndrome is a complex autoimmune disorder. The investigators hypothesize that striated ductal cells may function as non-professional antigen-presenting cells in Sjögren's syndrome.
- Trial name
- NCT06536075
- Testing
- Sialoscintigraphy
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus, Type 2, Pre-diabetes
Models of Nutrition From Continuous Glucose Monitors
With this study, researchers want to conduct ambulatory studies in which people (healthy, with T2D, or at-risk of T2D) will consume a variety of pre-set and conventional meals in free-living conditions while wearing one or more…
- Conditions
- Diabetes Mellitus, Type 2, Pre-diabetes, Diet Habit, Diet, Healthy
- Trial name
- NCT04991142
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Cryptosporidium Infection, Cryptosporidiosis
Study of Efficacy and Safety of ABO809 in Healthy Participants
The purpose of this Phase I controlled human infection model (CHIM) study was to determine if oral administration of a good manufacturing practice (GMP) supply of Cryptosporidium parvum oocysts (ABO809) to healthy volunteers…
- Trial name
- NCT05036668
- Testing
- Cryptosporidium parvum oocysts (ABO809)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Musculoskeletal Pain, Sedentary Behavior
Multidisciplinary Health Monitoring for Esports Players
This study aims to develop a holistic, multidisciplinary health monitoring/screening module that evaluates the health and performance parameters of esports players, and to apply and assess the effectiveness of an individualized…
- Conditions
- Musculoskeletal Pain, Sedentary Behavior, Diet Habit, Physiological Stress
- Trial name
- NCT07665333
- Testing
- Multidisciplinary Preventive Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Immobilization, Tonic, Fasting
A New Model of Acute Febrile Disease
The investigators want to establish a new model of acute febrile disease by mimicking the conditions seen in hospitalized patients in regards to inflammation, immobilisation and fasting.
- Conditions
- Immobilization, Tonic, Fasting, Endotoxemia, Metabolism
- Trial name
- NCT03158363
- Testing
- LPS, 36 hour immobilization and fast
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Comparison of Epitheliotrophic Ability Between Human Serum and Commercialized Human Platelet- Cell and Animal Model
The Effect of Platelet Lysate on Corneal Epithelial Wound healing---the Collection of Human Serum From Volunteers
"Poor corneal epithelialization problem" can be found in a lot of ocular surface disorders, including limbal insufficiency, dry eye, chemical burn and neurotrophic disorders.
- Trial name
- NCT02720146
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Childhood Obesity Pevention, Diet Quality
Healthy Children, Healthy Communities: Effectiveness of a Multilevel Rural Community Engagement Model for Improving Children's Dietary Intake in Family Child Care Homes
The purpose of this study is to find out whether a program called "Healthy Children, Healthy Communities" can help young children in rural areas eat healthier and improve their health.
- Conditions
- Childhood Obesity Pevention, Diet Quality, Feeding Behaviors, Health Behavior Change
- Trial name
- NCT07160530
- Testing
- EAT Family Style, Better Kid Care
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Vision Disorders
Bridging Animal and Human Models of Exercise-induced Visual Rehabilitation
This study will determine whether blood biomarker changes predict sight-saving benefits of exercise.
- Trial name
- NCT02911805
- Testing
- Aerobic exercise, Balance exercise
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Food Habits
Modifications in the Eating Habits of Adolescents of Secondary Education as a Result of a Nutritional Intervention
The objective of the study was to demonstrate the efficacy of a nutritional intervention based on the Social Cognitive Theory and the Transtheoric Model in the favorable modification of eating habits in adolescents of secondary…
- Trial name
- NCT03206476
- Testing
- Nutritional intervention based on the SCT and the TM, Nutritional information
- Where
- Mexico
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Gabriela Macedo Ojeda
Animal Model
Smart-gloves Hand Motion Tracking for Live Endoscopic Submucosal Dissection Training
Learning endoscopic submucosal dissection (ESD) is undertaken by experienced endoscopists in endoscopic mucosal resection and management of complications.
- Trial name
- EndoHandView (NCT06683326)
- Testing
- ROKOKO smart-glove
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Carol Davila University of Medicine and Pharmacy
ASD, GDD
Developmental Regression-related Disease Research and Achievement Transformation Innovation Team
The incidence rate of developmental regression is gradually increasing. In the early stages of children's development, both ASD and DD patients can experience developmental regression, which in turn aggravates cognitive function…
- Trial name
- NCT06155214
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chen Li
Time Restricted Feeding, Feeding Behavior
The Effects of Time-Restricted Eating Model
There is increasing evidence of the effects of the time-restricted diet model based on the daily intake of energy within a period of 8-12 hours on body weight control and metabolic parameters.
- Conditions
- Time Restricted Feeding, Feeding Behavior, Impulsive Behavior
- Trial name
- NCT04960969
- Testing
- Time-restricted feeding for 4 weeks
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Elif Emiroğlu
Animal Model, Pediatric
The Effect Of Animal-Assisted Intervention
The aim of the study is to examine the effect of animal-assisted practice on fear in children admitted to the emergency room.
- Conditions
- Animal Model, Pediatric, Emergencies, Fear
- Trial name
- NCT05824624
- Testing
- ANIMAL-ASSISTED INTERVENTION, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University