Clinical trials: Ankle Ligament Injury
Ankle Fracture
Is Deltoid Ligament Repair for Ankle Fracture Necessary?
The investigator hypothesizes that primary acute ankle deltoid ligament repair can help restore ankle radiographic congruity and functional outcomes.
- Trial name
- AnkleFX (NCT02863042)
- Testing
- Repair Deltoid Tendon, Ankle Fracture Without Deltoid Tendon Repair
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Ankle Sprains, Instability, Joint
Evaluation of Proprioception in Patients Treated With Surgical External Ankle Ligament Recontruction for Traumatic Ankle Instability
The objective of the study is to evaluate post-operatively the postural control through the Delos system with the Riva method of patients already treated surgically of external capsulo-ligament reconstruction due to ankle…
- Trial name
- ANKLE-PRO (NCT05868681)
- Testing
- Delos instrument (computerized balance board)
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- Istituto Ortopedico Rizzoli
Healthy, Chronic Ankle Instability, CAI
Relationship Between Muscle Strength and Balance
This study aims to examine the relationship between lower extremity muscle strength and balance and to compare these parameters between healthy individuals and individuals with lower extremity injuries.
- Conditions
- Healthy, Chronic Ankle Instability, CAI, Anterior Cruciate Ligament Injury, Muscle Strengh
- Trial name
- NCT07419750
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Biruni University
Ankle Sprains, Instability, Joint
Evaluation of Ankle Propriocement and Stability
The objective of the study is to evaluate the postural control and proprioception before and after external capsulo-ligament reconstruction for ankle instability.
- Trial name
- ANKLE-INT (NCT04362488)
- Testing
- Preoperative evaluation, Postoperative evaluation
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction
Donor Ankle Sensorimotor Recovery After ACL Reconstruction With a Peroneus Longus Tendon Autograft
This prospective longitudinal observational cohort study will characterize recovery of donor-ankle sensorimotor function in adults who have undergone primary anterior cruciate ligament reconstruction using a peroneus longus…
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction, Donor Site Complication
- Trial name
- NCT07762989
- Testing
- Anterior Cruciate Ligament Reconstruction Using a Peroneus Longus Tendon Autograft
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Gazi University
Ankle Fractures, Deltoid Ligament; Sprain (Strain) (Ankle)
The Benefit of Repairing the Deltoid Ligament in Unstable Ankle Fractures
Ankle fractures occur in 1 out of 800 persons a year and is a common injury. The deltoid ligament is necessary for the stability of the joint and guides choice of treatment.
- Trial name
- NCT06568276
- Testing
- Additional deep deltoid ligament suture
- Where
- 9 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Ostfold Hospital Trust
Ankle Sprain
Surgical Management of Lateral Ankle Instability: Modified Broström-Gould Versus Arthroscopic Allograft Reconstruction of the Anterior Talofibular and Calcaneofibular Ligaments.
Primary Objective: To clarify whether arthroscopic reconstruction with allograft provides tangible benefits over the modified open Broström-Gould technique, or if both are equivalent in efficacy and safety.
- Trial name
- NCT07200271
- Testing
- Arthroscopic reconstruction surgery, Open surgery
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad Francisco de Vitoria
Sprain
Etoricoxib in Acute Ankle Ligament Sprains
The aim of the study is to measure the effectiveness of treatment over 7 days with commonly used anti-inflammatory medications namely etoricoxib and diclofenac (Voltaren) on reducing the severity of pain, swelling and loss of…
- Trial name
- NCT00954785
- Testing
- Ankle brace, Diclofenac 50 mg tds, Etoricoxib 120 mg mane
- Where
- 2 sites in South Africa
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Cape Town
Lateral Ankle Sprain, Ankle Injuries
PRICE vs PEACE and LOVE in Adolescent Lateral Ankle Sprain Rehabilitation
This study compared two early management strategies for adolescents with first-time lateral ankle sprain: the traditional PRICE protocol (Protection, Rest, Ice, Compression, Elevation) combined with non-steroidal…
- Conditions
- Lateral Ankle Sprain, Ankle Injuries, Sprain of Lateral Ligament, Rupture of Ligaments at Ankle and Foot Level
- Trial name
- NCT07287020
- Testing
- PRICE + NSAIDs protocol, PEACE and LOVE protocol
- Where
- Lithuania
- Volunteers
- 76 people
- Sponsor
- Lithuanian University of Health Sciences
Acute Ankle Sprain, Ankle Ligament Rupture
Functional Treatment for Acute Ankle Sprains: Softcast Wrap Versus MOKcast
In this study we compare two treatment options for ankle sprains. 100 patients were randomised between a flexible cast treatment and a removable and adjustable brace made out of the same materials. Follow-up was 4 months.
- Conditions
- Acute Ankle Sprain, Ankle Ligament Rupture, Ankle Injuries
- Trial name
- NCT01586390
- Testing
- Functional treatment for ankle sprain using ankle cast, Ankle sprain treated with removable ankle support
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Spaarne Gasthuis
Ankle Injury
Surgical Versus Functional Treatment for Acute Ruptures of the Lateral Ligament Complex of the Ankle in Young Males - A Randomized Controlled Trial With a Mean of 14 Years Follow-up
The aim of this prospective randomized controlled trial was to compare the effectiveness of surgical and conservative treatment in acute lateral ligament injury of ankle.
- Trial name
- NCT00954330
- Testing
- lateral ligament surgery, functional treatment
- Where
- Finland
- Volunteers
- 51 people
- Sponsor
- Finnish Defense Forces
Sprains and Strains
Kinesio Tape Effects on Ankle Proprioception
The aim of the present study was to establish whether Kinesio Tape (KT) on the ankle (Kase protocol for the lateral ankle ligament) improves Joint Position Sense (JPS) in healthy volunteers immediately after its application and…
- Trial name
- NCT01792908
- Testing
- Kinesio tape
- Where
- Spain
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
ATFL, Lateral Ankle Instability
BioBrace® in Arthroscopic Brostrom Lateral Ankle Ligament Repair
The purpose of this investigation is to evaluate pre- and post-operative patient reported outcomes and functional scores after an all-arthroscopic Brostrom repair using either a suture anchor construct alone or suture anchors…
- Conditions
- ATFL, Lateral Ankle Instability, Anterior Talofibular Ligament, Anterior Talofibular Ligament Injury
- Trial name
- NCT07401095
- Testing
- Brostrom repair with augmentation, Brostrom repair without augmentation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Hancock Orthopedics
Ankle (Ligaments); Instability (Old Injury), Ankle Sprain
A Study on Reducing Opioid Use After Ankle Arthroscopy
Study Title Effect of a Postoperative Multimodal Analgesic Protocol Predominantly Based on Non-Opioid Medications vs Opioid-Based Analgesia on Pain After Ankle Arthroscopy: A Noninferiority Randomized Clinical Trial Purpose This…
- Conditions
- Ankle (Ligaments); Instability (Old Injury), Ankle Sprain, Talus Osteochondral Defect, Opioid Analgesia
- Trial name
- NCT07154433
- Testing
- Opioid Analgesic Regimen, Non-opioid analgesic regimen
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ankle (Ligaments); Instability (Old Injury)
Cryo-ultrasound Versus LASER Therapy on Ankle Sprain in Tennis Players
the effect cryo-ultrasound therapy and LASER therapy on the short-term recovery of tennis players with acute lateral ankle sprains.
- Trial name
- NCT06766318
- Testing
- group A will receive cryo-ultrasound therapy combined with conventional physical therapy for two months, LASER therapy
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- October 6 University
Ankle Sprain, Ankle (Ligaments); Instability (Old Injury)
Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy
Ankle arthroscopy is increasingly performed as a day-case procedure, making rapid recovery and efficient discharge critical. Anesthetic technique substantially influences postoperative recovery, yet high-quality evidence…
- Conditions
- Ankle Sprain, Ankle (Ligaments); Instability (Old Injury), Pain Management, ERAS
- Trial name
- NCT07460310
- Testing
- Total intravenous anesthesia combined with peripheral nerve block (TIVA + PNB) group, General anesthesia combined with peripheral nerve block (GA + PNB) group, Spinal anesthesia
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Instability, Joint, Ankle Sprains
Italian Version of The Cumberland Ankle Instability Tool (CAIT)
Study Design: Evaluation of the psychometric properties of a translated, culturally adapted questionnaire. Objective: Translating, culturally adapting, and validating the Italian version of the Cumberland Ankle Instability Tool…
- Conditions
- Instability, Joint, Ankle Sprains, Ankle Injuries, Sport Injury
- Trial name
- CAIT-I (NCT04644601)
- Where
- Italy
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Grade II and III Acute Lateral Ankle Ligament Injuries
Tape Versus Semirigid Versus Lace-up Ankle Support in the Treatment of Acute Lateral Ankle Ligament Injury.
The objective of this study is to compare tape versus semi rigid support versus lace up brace treatment for acute lateral ankle ligament injuries with regard to clinical outcome and cost effectiveness.
- Trial name
- NCT01126242
- Testing
- Tape, Semi rigid brace, Lace-up brace
- Where
- Netherlands
- Volunteers
- 182 people
- Sponsor
- Gelre Hospitals
ACL Injury, Kinesiotape
Kinesio Taping for the Knee and Ankle: Acute Impact on Balance, Proprioception, and ACL Risk
This study aims to evaluate and compare the acute effects of Kinesio taping applied to the knee and ankle on balance, proprioception, and anterior cruciate ligament (ACL) injury risk using the Landing Error Scoring System (LESS).
- Conditions
- ACL Injury, Kinesiotape, Balance, Proprioception
- Trial name
- ACL (NCT07138573)
- Testing
- Kinesio Taping (KT) applied to the knee then ankle, Kinesio Taping (KT) applied to the ankle then knee
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Ankle Sprains, Ligament Sprain
Construction and Validation of a Score Evaluating the Residual Instability of the Patient After Ankle Ligamentoplasty
The goal of this prospective, open label study is the construction and the evaluation of a composite score evaluating the residual instability in patients who have undergone an ankle's ligamentoplasty (the Ankle Go Test score).
- Trial name
- NCT05331365
- Testing
- Construction and evaluation of a composite score evaluating post ankle surgery residual instability by completing questionnaires and undergoing physical tests
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Elsan