Clinical trials: Anorectal Surgeries
Anorectal Diseases, Hemorrhoids
Comparative Analysis of Hypobaric Versus Hyperbaric Bupivacaine for Spinal Anesthesia in Day-Case Anorectal Surgery
Spinal anesthesia for anorectal surgery ( fistulotomy, fissure repair, pilonidal sinus excision,hemorrhoidectomy..) is a popular and widely used method characterized by rapid onset, delivery, easy mobilization and short hospital…
- Conditions
- Anorectal Diseases, Hemorrhoids, Anal Polyp, Pilonidal Sinus
- Trial name
- NCT05409820
- Testing
- use of different spinal anesthesia techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Pain, Postoperative
The Effect of Pain Education on Pain and Comfort
The study was planned as quasi-experimental to determine the effect of pain training given to patients who will undergo surgery for anorectal diseases on postoperative pain and comfort.
- Trial name
- NCT05692193
- Testing
- pain education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Okan University
Rectal Prolapse, Pelvic Organ Prolapse (POP)
RECTOSACROUTEROPEXY vs. WELLS
The goal of this clinical trial was to compare two surgical techniques in female patients with full-thickness rectal prolapse. The main questions it aimed to answer were: 1.
- Trial name
- RSUP (NCT07673406)
- Testing
- Modified rectosacrouteropexy, Wells rectopexy
- Where
- Azerbaijan
- Volunteers
- 36 people
- Sponsor
- Azerbaijan Medical University
Rectal Prolapse, Procidentia
An International Double Cohort Study to Compare Laparoscopic Ventral Rectopexy With Laparoscopic Resection Rectopexy
Background: Rectal prolapse (RP) is the descent of the upper rectum and is a common problem in the western world. Surgery is the only definite treatment and is preferably performed minimally invasive.
- Trial name
- LaProS (NCT01595412)
- Testing
- Laparoscopic Resection Rectopexy, Laparoscopic Ventral Rectopexy
- Where
- 6 sites in United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic
Anal Fistula, Anal Fissure Chronic
Effect of Enhanced Recovery After Surgery for Benign Anorectal Conditions
This study aims to assess the role of Enhanced recovery after surgery(ERAS) protocol in reducing postoperative urine retention (POUR) after surgery for benign anorectal conditions.
- Conditions
- Anal Fistula, Anal Fissure Chronic, Haemorrhoid, Enhanced Recovery After Surgery (ERAS) Protocol
- Trial name
- NCT06803550
- Testing
- Enhanced recovery after surgery protocol, Routine pathway
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Anorectal Disorder
Caudal Block,Saddle Block, Anorectal Surgery
Anorectal surgery includes pilonidal sinus, hemorrhoidectomy, anal fissure, and anal fistula operations. Various surgical and anesthetic techniques have been used to increase the level of analgesia in perioperative period and…
- Trial name
- NCT03498547
- Testing
- caudal block, saddle block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Anorectal Surgery Haemodynamic Changes
Haemodynamic Effects During Anorectal Surgery: a Comparison of the Jack -Knife and Lithotomy Position
Background and Goal of Study: Minimal dose of spinal hyperbaric bupivacaine is commonly performed for adult anorectal surgery. This kind of anaesthesia can cause sinus bradycardia and hypotension wich reason is body position…
- Trial name
- NCT02115178
- Testing
- Lithotomy or Prone position
- Where
- Lithuania
- Volunteers
- 155 people
- Sponsor
- Lithuanian University of Health Sciences
Hirschsprung Disease, Anorectal Malformations
Feasibility of Use of Indocyanine Green in Pediatric Colorectal Surgery
Hirschsprung's Disease (HD) and anorectal malformations (ARM) are both paediatric diseases of the colon and rectum. Both of these conditions require surgery in order to correct them, frequently needing sections of the bowel to be…
- Trial name
- NCT04904081
- Testing
- Indocyanine green
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Children, Anorectal Disorder
3D High Resolution Anorectal Manometry in Children After Surgery for Anorectal Disorders
3D high resolution anorectal manometry (3DHRAM) is the most precise tool to assess function and 3D topographic picture of pressures along the anal canal.
- Conditions
- Children, Anorectal Disorder, Anorectal Atresia, Hirschsprung Disease
- Trial name
- NCT02296008
- Testing
- 3D high resolution anorectal manometry
- Where
- Poland
- Volunteers
- 43 people
- Sponsor
- Medical University of Warsaw
Anorectal Malformations
Outcomes in ARMs: Comparison Between Surgical Techniques in Patients With Perineal or Vestibular Fistula - a Multicenter Italian Study
This is a national, multicenter, retro-prospective longitudinal cohort study evaluating mid- and long-term outcomes of different surgical techniques used for the correction of anorectal malformations (ARM) with perineal or…
- Trial name
- MAR-ITA (NCT07438691)
- Where
- 21 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Meyer Children's Hospital IRCCS
Department of Anorectal Surgery, Changhai Hospital Affiliated to Naval Medical University
A Randomized, Controlled, Multicenter, Noninferiority Clinical Study of Perioperative and Oncological Safety in Patients With Rectal Cancer
Laparoscopic natural orifice specimen extraction surgery (NOSES) for low rectal cancer has a good minimally invasive effect. However, the NOSES prognosis studies are all small sample retrospective studies.
- Trial name
- NCT05503381
- Testing
- Laparoscopic radical resection of low rectal cancer with transanal specimens
- Volunteers
- 500 people
- Sponsor
- Changhai Hospital
Rectum Cancer, Faecal Incontinence
Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer.
The occurrence of colorectal cancer has increased from the third most common cancer in 2018 to the second most common cancer in 2023.
- Conditions
- Rectum Cancer, Faecal Incontinence, Faecal Incontinence with Faecal Urgency, Low Anterior Resection Syndrome
- Trial name
- NCT06601985
- Testing
- J-pouch anastomosis, direct anastomosis
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Shanghai 10th People's Hospital
Anesthesia, Local
Ice as an Adjunct for Local Anesthesia During Anorectal Surgeries
The purpose of this study is to determine, among patients receiving elective anorectal surgery, does application of ice to the perianal area prior to the procedure, lead to use of decreased amounts of intravenous (IV) anesthesia?…
- Trial name
- NCT04000191
- Testing
- MAC, Perianal ice application
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Anorectal Diseases
Physiotherapy Applications in Children With Bladder and Bowel Symptoms After Anorectal Malformation Surgery
The aim of our study was to investigate the effects of physiotherapy applications in children with bladder and bowel symptoms after anorectal malformation surgery.
- Trial name
- NCT07075692
- Testing
- Physiotherapy
- Volunteers
- 20 people
- Sponsor
- Ankara Yildirim Beyazıt University
Hemorrhoids, Fissure in Ano
Pre-Emptive Analgesia in Ano-Rectal Surgery
The perianal region is the region around the anus. Administering a pain medication before a surgery starts is called preemptive analgesia.
- Conditions
- Hemorrhoids, Fissure in Ano, Rectal Fistula, Anal Condyloma
- Trial name
- PEAARS (NCT02402543)
- Testing
- Gabapentin, Ketamine, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Vermont
Fissure;Anal, Fistula;Rectal
Efficacy and Safety of CLIFE1 Gel in Benign Anorectal Surgery
Double-blinded multicenter randomized clinical trial to evaluate the efficacy and safety of CLIFE2 (lidocaine, referred as treatment A) respect CLIFE1 (lidocaine plus diclofenac, referred as treatment B) in benign anorectal…
- Conditions
- Fissure;Anal, Fistula;Rectal, Hemorrhoids
- Trial name
- NCT02961855
- Testing
- anesthesics plus antiinflammatory, CLIFE1, local anesthesics, CLIFE2
- Volunteers
- 120 people
- Sponsor
- Hospital de Viladecans
Anorectal Malformation, Hirschprung's Disease
Long-Term Health Outcomes in Children Born With Hirschsprung's Disease and Anorectal Malformations at the Colorectal Centre of Excellence in Quebec
The COCOE Registry is a long-term research registry based at the Montreal Children's Hospital Colorectal Centre of Excellence (COCOE) in Montreal, Quebec.
- Conditions
- Anorectal Malformation, Hirschprung's Disease, Colo-rectal Surgery, Fecal Incontinence
- Trial name
- NCT07603232
- Testing
- No intervention (observational study)
- Where
- Canada
- Volunteers
- 999 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Complications, Postoperative
Spontaneous Void Requirements for Patients Undergoing Ambulatory Anorectal Surgery
The objective of this study is to assess if not requiring patients to spontaneous void prior to discharge from the post-anesthesia care unit (PACU) will results in shorter lengths of stay in the post-anesthesia care unit without…
- Trial name
- NCT03812536
- Testing
- No Void
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Syed Husain
Anorectal Surgery, Pain Management
A Multidisciplinary Perioperative Pain Management
Objective: This study aimed to evaluate the clinical value of a multidisciplinary collaboration (MDC)-based perioperative pain management model.
- Trial name
- NCT07150819
- Testing
- Standard Nursing Care Protocol, MDC-based Pain Management
- Where
- China
- Sponsor
- China-Japan Friendship Hospital
Acute Pain, Post Operative Pain
Intrathecal Hydromorphone for Postoperative Pain of Anorectal Surgery
Anorectal problems, such as hemorrhoids, fistula, fissures, Etc., often require surgical treatment. Patients often have postoperative pain after these surgeries, which increases discomfort and hospital length of stay.
- Conditions
- Acute Pain, Post Operative Pain, Anorectal Disorder, Analgesia
- Trial name
- IMPAS (NCT05579223)
- Testing
- Intrathecal Hydromorphone Mono Injection
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine