Clinical trials: Anterior Cruciate Ligament (ACL)
Patellar Dislocation, ACL Injury
The Faroese Knee Cohort: Etiology and Long-term Implications of Trochlear Dysplasia and Patellar Dislocations.
The investigators intend to establish a national cohort including all persons in the ages from 15-20 years old with patellar instability (PI) or a prior knee injury (ACL-ruptur or meniscus damage) .
- Conditions
- Patellar Dislocation, ACL Injury, Meniscus Lesion, Trochlear Dysplasia
- Trial name
- FKC (NCT04607538)
- Testing
- No intervention is made
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
ACL, Anterior Cruciate Ligament Injury
Decreasing Knee Injury Risk Factors With Neuromuscular Training
Anterior cruciate ligament (ACL) tears are disabling injuries that place a significant burden on the athlete. Roughly 80% of these injuries are linked to a noncontact mechanism, with more than 70% of them occurring while landing…
- Trial name
- NCT01433718
- Testing
- Neuromuscular and Resistance Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio University
Anterior Cruciate Ligament Injury
Differential Biomechanical Effects of an ACL Injury Prevention Program in Women's Basketball and Soccer Players
Anterior cruciate ligament injury programs are less successful in women's basketball than soccer players, yet the reason for this discrepancy is unknown.
- Trial name
- NCT02530333
- Testing
- Neuromuscular Prevention Program
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- High Point University
Anterior Cruciate Ligament Injury, ACL
Mechanical Perturbation Training for ACL Injury Prevention
A prospective trial will be used to evaluate the efficacy of prophylactic mechanical perturbation training program. 24 female athletes who are regular participants in activities that involve cutting, pivoting, jumping, and…
- Trial name
- NCT03080402
- Testing
- Mechanical Perturbation Training
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Sports Injury, Orthopedic Disorder
Training of Falling Techniques on Landing Mechanics
The overall purpose of this study is to quantify the effect and retention of one-week training of falling techniques on landing biomechanics associated with anterior cruciate ligament (ACL) loading compared to soft-landing…
- Conditions
- Sports Injury, Orthopedic Disorder, Knee Injuries, Anterior Cruciate Ligament Injuries
- Trial name
- NCT04768088
- Testing
- Falling Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Anterior Cruciate Ligament Injuries
Adding Neurocognitive Component to Balance Test
By introducing BlazePods as a neurocognitive addition to the YBT, this study aims to determine whether this addition impacts balance performance and/or reach distances between the operative and non-operative limbs of patients…
- Trial name
- NCT06827483
- Testing
- Neurocognitive Component
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Football Players, Sport Injury
Neuromuscular and Proprioceptive Training in Football Players
The objective of this study was to determine the effect of proprioceptive and neuromuscular training on landing errors and balance of the football players.
- Conditions
- Football Players, Sport Injury, Sports Physical Therapy
- Trial name
- NCT04051554
- Testing
- Neuromuscular and Proprioceptive Training, Conventional Training
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Knee Injuries, Athletic Injuries
Risk Factors for Anterior Cruciate Ligament (ACL) Injury
The anterior cruciate ligament (ACL) is located inside the knee joint and provides stability to the knee. ACL injuries occur more frequently in women than men; the reason for this is unknown.
- Trial name
- NCT00124319
- Where
- 3 sites in United States
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- Steve Marshall
ACL Injury, Postoperative Pain
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2.
- Trial name
- NCT04246554
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
ACL Injury, Gait
The Influence of Running to ACL Deficiency
The aim of this study is to investigate the influence of running to kinematic parameters of patients with anterior cruciate ligament.
- Trial name
- NCT03135600
- Testing
- Procedure
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
ACL - Anterior Cruciate Ligament Rupture, ACL Injury
Longitudinal Assessment of Cartilage Injury and Remodeling After Anterior Cruciate Ligament Rupture and Reconstruction:
The proposed study will establish novel relationships between intra-articular mesenchymal stem cell (MSC) recruitment, synovial inflammation, biomarkers of cartilage degeneration and joint inflammation, clinical patient factors…
- Conditions
- ACL - Anterior Cruciate Ligament Rupture, ACL Injury, Healthy
- Trial name
- NCT03497780
- Testing
- Anterior cruciate ligament reconstruction
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
ACL Injury
Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes
Females who participate in cutting and landing sports suffer anterior cruciate ligament (ACL) injuries at a 2 to 10-fold greater rate than males participating in the same high-risk sports.
- Trial name
- NCT01034527
- Testing
- Neuromuscular Training
- Where
- United States
- Volunteers
- 593 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Injury of Anterior Cruciate Ligament
Feasibility Trial Using Imaging and Biochemical Technologies to Measure Knee Cartilage Composition in Acute ACL Injury
This study will evaluate the bio-mechanical and biochemical abnormalities in acute ACL-injured knees over time. Data will be collected through advanced quantitative MR imaging, functional testing, and bio-specimen collection.
- Trial name
- NCT02010125
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anterior Cruciate Ligament Tear, Medial Collateral Ligament
A Study to Evaluate the Incrediwear Products Immediately After ACL Repair
To assess the benefits of using the Incrediwear knee products after ACL or ACL+MCL arthroscopic surgery, on the postoperative pain, range of motion and effusion.
- Trial name
- NCT06668376
- Testing
- Leg Sleeve
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Texas Bone and Joint
Scarring
Medipore Tape Study
This is a prospective, single-blinded, two-arm, randomized, parallel, pragmatic, effectiveness trial that will enroll patients undergoing arthroscopic anterior cruciate ligament reconstruction in order to evaluate the efficacy of…
- Trial name
- NCT02676115
- Testing
- Standard Post Operative Skin Care, Medipore Tape
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Anterior Cruciate Ligament Injury
Maximum Oxygen Uptake in ACL-injured Professional Soccer Players
Our purpose is to evaluate maximum oxygen uptake (VO2max) in ACL-injured professional soccer players and after a six-month period of post-operative rehabilitation, compared to a control group of healthy professional soccer…
- Trial name
- NCT02674282
- Testing
- ACL reconstruction
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
ACL Injury
Effects of HMB Supplementation on Recovery Following ACL Surgery
The anterior cruciate ligament (ACL) is a primary stabilizer of the knee, and thus when ACL injury occurs participation in physical activity is compromised.
- Trial name
- NCT02602561
- Testing
- HMB
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
ACL - Anterior Cruciate Ligament Rupture
BioACL Reconstruction With Amnion Collagen Matrix Wrap and Stem Cells Case Series
The objective of this study is to evaluate the use of wrapping an ACL graft with a collagen matrix tissue wrap and injecting autologous bone marrow aspirate concentrate under the wrapping and into the graft.
- Trial name
- BioACL(CS) (NCT03294720)
- Testing
- Bio-ACL, amnion wrap and BMAC
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Andrews Research & Education Foundation
Double Leg Vertical Jump (DLVJ), Single Leg Squat (SLS)
ESSKA/ESMA ACL Injury Prevention Program in Czech Sport
This study aims to address the rising incidence of ACL injuries, particularly among adolescents, by developing and implementing a comprehensive prevention program based on the evidence-based "ACL Prevention for ALL" framework…
- Conditions
- Double Leg Vertical Jump (DLVJ), Single Leg Squat (SLS), Single Leg Drop Landing (SLDL), Drop Jump Test (DJ Test)
- Trial name
- NCT07019727
- Testing
- ESSKA/ESMA 'ACL Prevention for All' methodology
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Rehabilitative Nutrition for Muscle Recovery From ACL Reconstruction
Protein in Feeding Strategies to Accelerate Muscle Recovery From ACL Reconstruction
Musculoskeletal injury, particularly injuries requiring surgical repair, induce significant muscle atrophy, resulting in diminished physical function.
- Trial name
- NCT03492021
- Testing
- Diet Intervention_AP-CPT, Diet Intervention_PP-PPT
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Connecticut