Clinical trials: Anthocyanins
Type 2 Diabetes
Effect of Soft Fruit on Postprandial Blood Glucose
Dietary strategies for alleviating health complications associated with type 2 diabetes (T2D) are being pursued as alternatives to pharmaceutical interventions.
- Trial name
- NCT02291250
- Testing
- Blackcurrants with polycal OGTT, Greencurrants with polycal OGTT, Blackcurrants with glucose OGTT
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Inflammation
The Effects of Antioxidants in Blueberry Powder on Inflammation Induced by a Single High Fat Meal.
The goal of the study is to find out whether a high fat meal increases blood lipids and causes monocyte (white blood cell) activation, and whether blueberry intake at the same meal lessens monocyte activation in healthy people.
- Trial name
- FL89 (NCT01594008)
- Testing
- Breakfast meal with 2 serving equivalents of blueberries, Breakfast meal with 4 serving equivalents of blueberries
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Toxicity Due to Radiotherapy
Supplementation With Dietary Anthocyanins and Side Effects of Radiotherapy for Breast Cancer
Attention has been focused recently on the development of modalities that can protect healthy organs from the harmful effects of radiation applied during different cancer treatment schedules.
- Trial name
- ATHENA (NCT02195960)
- Testing
- intake anthocyanin-rich corn extract
- Where
- Italy
- Volunteers
- 242 people
- Sponsor
- Neuromed IRCCS
Cognition - Other, Depression, Anxiety
Effects of a Black Rice Extract and Anthocyanidin Metabolites on the Synthesis and Release of BDNF in Healthy Subjects
The goal of this clinical trial is to investigate the effect of black rice extract (BRE) supplementation on levels of BDNF, which is a key molecule in cognition in healthy volunteers.
- Trial name
- NCT06594848
- Testing
- Black rice extract
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy, Metabolic Syndrome
Effect of Cherry Juice on Fat Oxidation and Cardio-metabolic Markers
The present study examined the effect of Montmorency tart cherry juice and FATMAX (intensity eliciting maximal fat oxidation) exercise on fat oxidation rates, body composition and blood-based cardio-metabolic markers.
- Trial name
- NCT02999256
- Testing
- Montmorency Tart Cherry Juice
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Hertfordshire
Vascular Stiffness, Inflammation
Anthocyanin-rich Blackcurrant and Vascular Function
Regular consumption of fruits and vegetables may improve human health and reduce the risk of chronic diseases, such as heart disease, certain cancers and type 2 diabetes, but the active components and the underlying mechanisms…
- Trial name
- NCT02459756
- Testing
- Beverage: Spray dried blackcurrant powder dissolved in water
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Reading
Hyperlipidemia
Bilberry Fruit and Black Rice Derived Anthocyanins on Lipid Status
The primary aim of this study is to directly compare the two major types of anthocyanins found in the diet (cyanidin-type and delphinidin-type) on lipid status in adults.
- Trial name
- NCT03213288
- Testing
- Delphinidin type anthocyanins, Cyanidin type anthocyanins
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Metabolic Syndrome
Pivotal Assessment of the Effects of Bioactive on Health and Wellbeing. From Human Genome to Food Industry
This is a multi-centre, randomised, double-blind, placebo-controlled, parallel-arm dietary intervention study. In total, 800 men and women at risk for Metabolic Syndrome (MS) will be recruited.
- Trial name
- PATHWAY-27 (NCT02702713)
- Testing
- Dairy BEF, Egg BEF, Bakery BEF
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Colorectal Cancer
Anthocyanin-Rich Berry Supplementation in Patients With Colorectal Cancer
This prospective, open-label interventional study evaluated the effects of short-term supplementation with an anthocyanin-rich freeze-dried black raspberry and strawberry preparation in patients undergoing treatment for…
- Trial name
- NCT07819539
- Testing
- Anthocyanin-Rich Freeze-Dried Berry Supplement
- Where
- Poland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Coffee, Anthocyanins
Short-term Effects of Caffeine and a Multi-ingredient Pre-workout on Exercise Performance
The investigators are conducting a study to see how a commercial pre-workout supplement, coffee, and water affect how well people perform. The study is conducted across four visits.
- Conditions
- Coffee, Anthocyanins, Exercise Performance
- Trial name
- NCT07024940
- Testing
- Ethiopian Coffee, Supplement
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Iron Deficiencies, Inflammation
Effect of Supplementation With Anthocyanins on Iron Metabolism in Female Swimmers
The study included 8-weeks supplementation of black chokeberry extract with 18% standardization of the anthocyanins content (dose 2×200 mg per day), or a placebo product that was made from chokeberry fiber.
- Conditions
- Iron Deficiencies, Inflammation, Oxidative Stress, Female Athlete Triad
- Trial name
- NCT06486623
- Testing
- Black chokeberry extract in capsules with 18% standardization of the anthocyanins content, Chokeberry fiber in capsules
- Where
- Poland
- Volunteers
- 22 people
- Sponsor
- Poznan University of Physical Education
Healthy
Anthocyanin & Phenolic Acids Bioavailability & Antioxidant Capacity After Consumption of Purple Wheat Products in Adults
This study will determine the bioavailability of anthocyanins and phenolic compounds from two purple wheat products, i.e. bran-enriched wholegrain purple wheat crackers and bran-enriched wholegrain purple wheat granola bars.
- Trial name
- NCT02730910
- Testing
- Purple Wheat Crackers, Purple Wheat Granola Bars
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Guelph
General Anxiety Disorders, Systemic Inflammation
Effects of Mulberry Juice on Inflammatory Status and Clinical Symptoms in Patients With General Anxiety Disorder
Anxiety and depression are normally associated with inflammation reactions and interleukin (IL) related pathways are most evidently involved.
- Conditions
- General Anxiety Disorders, Systemic Inflammation, Interleukin
- Trial name
- NCT03935061
- Testing
- Mulberry juice
- Where
- Taiwan
- Volunteers
- 104 people
- Sponsor
- Taipei Medical University
Blindness and Low Vision
Blueberry Effects on Dark Vision and Glare Recovery
Clinical evidence for effects of plant anthocyanins on vision, and particularly night vision is controversial. Two clinical trials were conducted to investigate whether blueberry juice consumption affected visual dark adaptation…
- Trial name
- NCT01942746
- Testing
- Blueberry Juice S2, Blueberry Capsules S2, Blueberry Juice L1
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Atlantic Food and Horticulture Research Center
Cardiovascular Disease
The Orange Juice and Cardiovascular Disease Study
This study aims to compare the effect of an anthocyanin-rich blood orange juice with a standard (no anthocyanin) blonde orange juice on markers of cardiovascular disease (CVD).
- Trial name
- OJ & CVD (NCT02195934)
- Testing
- Standard (blonde) orange juice, Blood orange juice
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Overweight and Obesity
Effect of Açaí Juçara Consumption on Endothelial Function and Arterial Stiffness
This study evaluates the consumption of Açaí Juçara pulp in endothelial function and arterial stiffness in overwheight and obese individuals.
- Trial name
- NCT04434534
- Testing
- Hipocaloric Diet with Açaí Juçara, Hipocaloric Diet
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Dry Eye
Bilberry-containing Capsules for Dry Eye Mitigation
This study investigates whether the oral intake of a bilberry capsule product may relieve dry eye symptoms. Participants will be aged between 20 - 65 years of age, with confirmed diagnosis of dry eye status.
- Trial name
- NCT05737108
- Testing
- Bilberry capsule product
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chung Shan Medical University
Depressive Symptoms
Blueberries, Inflammation, Motivation, and Physical Activity
The purpose of this study is to determine the feasibility and preliminary efficacy of daily supplementation of freeze-dried blueberry to modulate inflammation-driven lack of motivation in 40 sedentary, older adults with…
- Trial name
- NCT05735587
- Testing
- Freeze-dried Blueberry Powder
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Hebrew SeniorLife
Myopia, Visual Fatigue
Discussion on the Effectiveness of Tea on Blood Pressure, Body Composition and Vision Problems in College Students
Background: Tea is a universal beverage and one of the most popular drinks around the world. Some cell and animal experiments have pointed out that drinking tea may be related to hypotension, body composition and vision problems…
- Conditions
- Myopia, Visual Fatigue, Blood Pressure, Body Composition
- Trial name
- NCT06570226
- Testing
- hibiscus tea
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Gout
Pharmacokinetics and Pharmacodynamics of Anthocyanins
The purpose of the study is to establish the pharmacokinetic parameters of cherry juice concentrate and identify its potential to alter inflammatory markers in gout patients.
- Trial name
- NCT03650140
- Testing
- Tart cherry extract 60 mL, Tart cherry extract 120 mL
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rutgers, The State University of New Jersey