Clinical trials: Anti-Infective Agents
HIV Infections, HIV Seronegativity
HIV Prevention Preparedness Study
The purpose of this study is to provide researchers with information that will help them prepare for a future study to test the efficacy of two anti-HIV vaginal gels.
- Trial name
- NCT00048282
- Where
- 10 sites in South Africa, Tanzania and 1 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Antibacterial Agents
Evaluation of a Customizable Antibiotic Stewardship Program Tailored to French Nursing Homes
To tackle antimicrobial resistance (AMR), i.e., one of the top 10 global health threats, antimicrobial stewardship (AMS) programs, i.e., coherent sets of actions promoting responsible use of antimicrobials, have been developed.
- Trial name
- ORANEAT (NCT07246382)
- Testing
- The ORANEAT program
- Where
- 2 sites in France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Lorraine
Covid19
the Investigation Into Beneficial Effects of High-dose Interferon Beta 1-a, Compared to Low-dose Interferon Beta 1-a in Moderate to Severe Covid-19
The present study is a randomized clinical trial, with the approval of the ethics committee will be conducted on patients who have a positive test confirming COVID-19 in Loghman Hakim Medical Education Center in Tehran.
- Trial name
- NCT04521400
- Testing
- High dose Interferon-beta 1a, Lopinavir/Ritonavir, Low dose Interferon-beta 1a
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Bacterial Infection, Anti-infective Agents
Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction
Antibiotics are used routinely in postoperative tissue expander based breast reconstruction (TE) and autologous flap (AF) breast reconstruction procedures.
- Conditions
- Bacterial Infection, Anti-infective Agents, Breast Implantation
- Trial name
- NCT01244698
- Testing
- Cefadroxil discontinued early, Cefadroxil until drain removal
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Tuberculosis, Tuberculosis, Pulmonary
Pharmacokinetics, Safety and Tolerability of Escalating Rifapentine Doses in Healthy Volunteers
The aim of this study is to evaluate (1) the safety and tolerability of escalating doses of rifapentine (RPT) administered daily by oral; (2) the effect of increasing doses of RPT on cytochrome P450 isoform 3A (CYP3A) enzyme…
- Trial name
- TBTC S29B (NCT01162486)
- Testing
- Rifampin & midazolam, rifapentine & midazolam, rifapentine and midazolam
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Vaccines, Antiviral Agents
Screening of Volunteers for Clinical Trials of Investigational or Licensed Vaccines or Antiviral Products
Background: Vaccines and antiviral therapies help prevent and treat diseases. Researchers need a group of healthy volunteers for clinical trials. Clinical trials are studies that test these vaccines and therapies in people.
- Conditions
- Vaccines, Antiviral Agents, Immunologic Factors, Physiological Effects of Drugs
- Trial name
- NCT02242968
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Hepatitis B, Chronic
Safety and Acceptability of a Vaginal Microbicide
The purpose of this study is to determine the safety and acceptability of a vaginal microbicide in HIV uninfected sexually active women.
- Trial name
- NCT00111943
- Testing
- 1% tenofovir gel
- Where
- 3 sites in United States, India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Diarrhea
Impact of Bismuth Subsalicylate on Antimicrobial Use Among Adult Diarrhea Outpatients--Pakistan
The purpose of this study is to learn whether bismuth subsalicylate can reduce use of antibiotics among adults with diarrhea in Pakistan.
- Trial name
- NCT02047162
- Testing
- Bismuth subsalicylate
- Where
- Pakistan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Periodontitis
Clarithromycin is an Adjunct to Scaling and Root Planing
The present study was done to evaluate the effect of clarithromycin as an adjunct to scaling and root planning at baseline, three months and six months intervals .
- Trial name
- CASRCMI (NCT02359721)
- Testing
- tablet clarithromycin 500 mg (Clarino-500) orally
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre