Clinical trials: Anticoagulant Toxicity
Atrial Fibrillation, Medication Adherence
Adherence and Coagulation Assays in Dabigatran-treated Patients With Atrial Fibrillation
In patients with non-valvular atrial fibrillation treated with dabigatran etexilate, the level of adherence will be measured using a questionnaire, the Danish National Prescription Registry and pillcount and will be related to…
- Conditions
- Atrial Fibrillation, Medication Adherence, Blood Coagulation Tests, Anticoagulants; Circulating, Hemorrhagic Disorder
- Trial name
- ARCADE (NCT03280368)
- Testing
- Bloodtest, Questionnaires
- Where
- Denmark
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Hospitalsenheden Vest
Safety Issues, Anticoagulant Toxicity
Clinical Pharmacist Anticoagulant Stewardship
Initiative to improve direct anticoagulant utilization involving programmatic review by clinical pharmacists in collaboration with multidisciplinary team.
- Trial name
- NCT03527615
- Testing
- Clinical Pharmacist Medication Review
- Where
- Israel
- Volunteers
- 4,000 people
- Sponsor
- Hadassah Medical Organization
ESRD, Anticoagulant Toxicity
Apixaban in End-stage Kidney Disease : A Pharmacokinetics Study
Apixaban is a novel oral direct factor Xa inhibitor; In patients with atrial fibrillation, apixaban was superior to warfarin in preventing stroke or systemic embolism, caused less bleeding, and resulted in lower mortality (the…
- Trial name
- NCT03456648
- Testing
- apixaban
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Anticoagulant Antagonist Toxicity
Strategies for Protamine Dosing After Anticoagulation in Cardiovascular Surgery
In cardiovascular surgery, patients are anticoagulated with heparin during cardiopulmonary bypass, subsequently, anticoagulation is reversed with protamine to reduce bleeding due to residual heparin-induced coagulopathy, which…
- Trial name
- SEPARATION (NCT04628884)
- Testing
- Conventional dose, Dosing according residual heparin
- Where
- Colombia
- Volunteers
- 136 people
- Sponsor
- Fundación Clínica Shaio
Hemodialysis Complication, Acute Kidney Injury
Evaluation of Regional Anticoagulation With Citrate in Extended Hemodialysis
Data on regional citrate anticoagulation in patients with acute kidney injury (AKI) treated by hybrid or extended dialysis are scarce and heterogeneous.
- Conditions
- Hemodialysis Complication, Acute Kidney Injury, Anticoagulant Toxicity
- Trial name
- NCT04297839
- Testing
- Citrate Anticoagulation Solution, Control Group (heparin or continuous saline)
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo General Hospital