Clinical trials: Anxiety, Generalized
Anxiety Disorders, Separation Anxiety Disorder
Treatment Study for Rural Latino Youth With Anxiety
This pilot study will examine the feasibility of two modes of service delivery (e.g., a minimal therapist contact, self-help program, and a more intensive therapist supported, telephone-based approach) in a rural, primarily…
- Conditions
- Anxiety Disorders, Separation Anxiety Disorder, Social Anxiety Disorder, Specific Phobia
- Trial name
- NCT01491880
- Testing
- Therapist-Assisted by Telephone, Self-Help
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of California, San Diego
Social Phobia, Generalized Anxiety Disorder
Brain Markers of Anxiety Disorders and SSRI/CBT Treatment in Children and Adolescents
This study will attempt to identify gene and brain activity markers that predict whether children and adolescents with anxiety disorders will respond to selective serotonin reuptake inhibitor medications or Cognitive Behavioral…
- Conditions
- Social Phobia, Generalized Anxiety Disorder, Separation Anxiety Disorder
- Trial name
- NCT01160588
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Generalized Anxiety Disorder
A Study of Duloxetine in Elderly Generalized Anxiety Disorder
The purpose of this study is to test the safety and efficacy of duloxetine versus placebo in elderly patients suffering from generalized anxiety disorder (GAD).
- Trial name
- NCT01118780
- Testing
- Duloxetine
- Where
- 25 sites in United States, Argentina and 7 more
- Volunteers
- 291 people
- Sponsor
- Eli Lilly and Company
Generalized Anxiety Disorder
A Clinical Trial to Study the Effects of Sensoril® for Patients With Generalized Anxiety Disorder
Sensoril - Extracts of Withania somnifera (Ashwagandha in Ayurvedic Medicine) have shown potent anti-stress, cortisol lowering, GABAergic, serotonergic and antioxidant properties in animal and human studies.
- Trial name
- NCT01311180
- Testing
- Sensoril®
- Where
- 7 sites in India
- Volunteers
- 120 people
- Sponsor
- Natreon, Inc.
Generalized Anxiety Disorder
A Study of JNJ-99245354 (ITI-1284) as an Adjunctive Treatment in Participants With Generalized Anxiety Disorder (GAD) Who Have an Inadequate Response to GAD Treatment
The purpose of this study is to assess if JNJ-99245354 administered once daily works better to reduce anxiety compared to placebo when given as an additional (adjunctive) therapy in participants with generalized anxiety disorder…
- Trial name
- NCT07856420
- Testing
- JNJ-99245354
- Volunteers
- 705 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Generalized Anxiety Disorder
Study of Efficacy and Safety of Vortioxetine (Lu AA21004) in Treating Generalized Anxiety Disorder
The purpose of this study is to evaluate the safety and efficacy of 2.5 mg and 10 mg vortioxetine, once daily (QD), in adults with generalized anxiety disorder.
- Trial name
- NCT00731120
- Testing
- Vortioxetine
- Where
- 40 sites in United States
- Volunteers
- 457 people
- Sponsor
- Takeda
Generalized Anxiety Disorder, Anxiety Disorder NOS
Calmer Life: Testing the Effectiveness of a Treatment for Anxiety
The overall goals of the proposed research study are to: (1) examine quantitative outcomes in a well-conducted randomized clinical trial of Calmer Life, relative to Enhanced Community Care, an information and referral…
- Trial name
- NCT01702220
- Testing
- CBT, ECC
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Baylor College of Medicine
Generalized Anxiety Disorder
Efficacy and Safety Study of a IMSS Developed Phytopharmaceutical for the Treatment of Anxiety.
The investigator's group at the Mexican Institute of Social Security has worked for more than 20 years in the scientific research of the plant species Galphimia glauca Cav., which is used in Mexican Traditional Medicine for the…
- Trial name
- Alpra (NCT03702803)
- Testing
- Galphimia glauca standardized extract, alprazolam 1mg
- Where
- Mexico
- Volunteers
- 122 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Suicide, Depression
Adaptation of a French E-health Tool for Suicide Prevention in Young Populations
"France's suicide rate is among the highest in Europe, with the young among the more at risk. Several European projects have demonstrated the effectiveness of using e-tools in suicide prevention particularly for hard-to-reach…
- Conditions
- Suicide, Depression, Psychological Distress, Anxiety Disorders
- Trial name
- E-psYouth (NCT04946955)
- Testing
- Application and website with or without promotion
- Where
- France
- Volunteers
- 12,000,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depressive Disorder, Major
Identifying Very Early Response to Seroquel Extended Release (XR) Augmentation for Major Depressive Disorder
The proposed study is for a 6 week open-label clinical trial in which Seroquel XR is added to a selective serotonin reuptake inhibitor (SSRI) medication for the treatment of depressive and/or anxiety symptoms.
- Trial name
- NCT00892463
- Testing
- Quetiapine (Seroquel) XR
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Sunnybrook Health Sciences Centre
Excessive Worry
Development of a Scientifically Informed Written Exposure Procedure (The SCRIPTS Study)
Generalized anxiety disorder (GAD) is characterized by excessive and uncontrollable worry and anxiety. When people with GAD worry, they tend to think about problems and feared situations in a vague way.
- Trial name
- NCT03654625
- Testing
- Standard Written Exposure, Enhanced Written Exposure, Control Condition
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Toronto Metropolitan University
Anxiety Disorders
Prevention of Relapse Study of SR58611A in Improved Patients With Generalized Anxiety Disorder
The purpose of the study is to evaluate the efficacy and safety of SR58611A (350 mg BID) compared to placebo in the prevention of relapse of anxiety, in patients with Generalized Anxiety Disorder improved after 12 weeks of…
- Trial name
- VEGA (NCT00397098)
- Testing
- SR58611A
- Where
- 9 sites in Australia, Chile and 7 more
- Volunteers
- 257 people
- Sponsor
- Sanofi
Generalized Anxiety, Introspective & Anxiety-Prone Patient
Validation of a Rapid Screening Tool for Anxiety-depressive Disorders in Children, Adolescents and Young Adults Treated in Oncology. Multicenter Study.
In France today, it is estimated that one in every 850 people aged between 20 and 45 is a childhood cancer survivor (CCS), equivalent to around 40,000 to 50,000 people.
- Conditions
- Generalized Anxiety, Introspective & Anxiety-Prone Patient, Depression, Anxiety, Survivors of Childhood Cancer
- Trial name
- HARMONY-Tool (NCT07117058)
- Testing
- New rapid screening tool for anxiety and depressive disorders, SCARED-R-51 (Screen for Child Anxiety Related Emotional Disorders-Revised), HADS (Hospital Anxiety and Depression Scale)
- Where
- 7 sites in France
- Volunteers
- 545 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Oral Surgical Procedures, Surgery, Oral
Effect Site Controlled, Reaction Time Safeguarded, Patient Maintained Sedation With Propofol in Anxious Patients
Whether patient-maintained sedation (the patient controls his/her degree of sedation using a hand-held device) using the drug propofol is safer and more effective when using deteriorating reaction time as an added safeguard…
- Conditions
- Oral Surgical Procedures, Surgery, Oral, Dental Anxiety, Surgery
- Trial name
- NCT00355693
- Testing
- Pump for propofol delivery
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Glasgow
Anxiety Disorders
An Eight-Week Study to Evaluate the Efficacy and Safety of SR58611A in Patients With Generalized Anxiety Disorder
The purpose of the study is to evaluate the efficacy and safety of SR58611A in patients with Generalized Anxiety Disorder. The primary objective is to evaluate the efficacy of a 700 mg dose of SR58611A compared to placebo in…
- Trial name
- AQUARIUS (NCT00266747)
- Testing
- SR58611A
- Where
- 7 sites in Argentina, Austria and 5 more
- Volunteers
- 366 people
- Sponsor
- Sanofi
Phobia, Social, Panic Disorder
Sertraline in Generalized Social Phobia With Co-Occurring Anxiety and Mood Disorders
Selective serotonin reuptake inhibitors (SSRIs) including sertraline have been found to be effective in the treatment of generalized social phobia (GSP).
- Conditions
- Phobia, Social, Panic Disorder, Agoraphobia, Obsessive-Compulsive Disorder
- Trial name
- NCT00182533
- Testing
- Sertraline
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- Hamilton Health Sciences Corporation
Generalized Anxiety Disorder
Attention Training for Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) has high prelevance (up to 8.5%; Roy-Byrne \& Wagner, 2004) and leads to functional impairment (Wittchen et al., 2002; Ballenger et al., 2001).
- Trial name
- NCT00602563
- Testing
- AMP, Applied Relaxation (AR), Clinical Monitoring (CM)
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- San Diego State University
Anxiety Disorders, Cardiovascular Diseases
Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population
The treatment of generalized anxiety disorder (GAD) in an accessible manner represents an unmet need for those with cardiovascular disease (CVD), given that patients with CVD experience numerous barriers for in-person treatment…
- Conditions
- Anxiety Disorders, Cardiovascular Diseases, Anxiety, Health Behavior
- Trial name
- NCT04895995
- Testing
- Daylight dCBT Application
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston University Charles River Campus
Preoperative Anxiety, Perioperative Complication
Binaural Beat Stimulation to Improve Patient Outcome After Surgery and Anesthesia
We plan to evaluate the potential of binaural beat stimulation as a cost-effective tool to improve perioperative patient outcome.
- Trial name
- NCT05533112
- Testing
- Binaural Beat Stimulation
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Technical University of Munich
Generalized Anxiety Disorder
Short-Term Efficacy and Mechanisms of Change of a Worry Postponement Intervention for Generalized Anxiety Disorder
Worry postponement is a commonly recommended treatment component in cognitive behavioral therapy for Generalized Anxiety Disorder in which people are asked to postpone naturally occurring instances of worry to a designated 30…
- Trial name
- NCT02806271
- Testing
- Worry Postponement, Worry Monitoring
- Where
- Canada
- Volunteers
- 83 people
- Sponsor
- Toronto Metropolitan University